-
1
-
-
0023948926
-
Regional distribution of cytochrome P450 in the rat brain: Spectral quantitation and contribution of P-450b,e and P-450c,d
-
Warner M, Kohler C, Hansson T, Gustafsson J-A. Regional distribution of cytochrome P450 in the rat brain: spectral quantitation and contribution of P-450b,e and P-450c,d. J Neurochem 1988;50:1057-65.
-
(1988)
J Neurochem
, vol.50
, pp. 1057-1065
-
-
Warner, M.1
Kohler, C.2
Hansson, T.3
Gustafsson, J.-A.4
-
3
-
-
0034017040
-
Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment
-
Miksys S, Hoffmann E, Tyndale RF, Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment. Biochem Pharmacol 2000;59:1501-11.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1501-1511
-
-
Miksys, S.1
Hoffmann, E.2
Tyndale, R.F.3
-
4
-
-
0036736195
-
Regional and cellular expression of CYP2D6 in human brain: Higher levels in alcoholics
-
Miksys S, Rao Y, Hoffmann E, Mash DC, Tyndale RF. Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics. J Neurochem 2002;82(6):1376-87.
-
(2002)
J Neurochem
, vol.82
, Issue.6
, pp. 1376-1387
-
-
Miksys, S.1
Rao, Y.2
Hoffmann, E.3
Mash, D.C.4
Tyndale, R.F.5
-
5
-
-
0035049437
-
Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain
-
Siegle I, Fritz P, Eckhardt K, Zanger UM, Eichelbaum M. Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain. Pharmacogenetics 2001;11:237-45.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 237-245
-
-
Siegle, I.1
Fritz, P.2
Eckhardt, K.3
Zanger, U.M.4
Eichelbaum, M.5
-
7
-
-
0027976519
-
Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs
-
Ghersi-Egea JF, Leininger-Muller B, Suleman G, Siest G, Minn A. Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J Neurochem 1994;62:1089-96.
-
(1994)
J Neurochem
, vol.62
, pp. 1089-1096
-
-
Ghersi-Egea, J.F.1
Leininger-Muller, B.2
Suleman, G.3
Siest, G.4
Minn, A.5
-
8
-
-
0033049368
-
Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization
-
Dey A, Jones JE, Nebert DW. Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization. Biochem Pharmacol 1999;58:525-37.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 525-537
-
-
Dey, A.1
Jones, J.E.2
Nebert, D.W.3
-
9
-
-
0034418176
-
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P450 1A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor nuclear translocator in rat brain pituitary
-
Huang P, Rannug A, Ahlbom E, Hakansson H, Ceccatelli S. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P450 1A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor nuclear translocator in rat brain pituitary. Toxicol Appl Pharmacol 2000;169:159-67.
-
(2000)
Toxicol Appl Pharmacol
, vol.169
, pp. 159-167
-
-
Huang, P.1
Rannug, A.2
Ahlbom, E.3
Hakansson, H.4
Ceccatelli, S.5
-
11
-
-
0025859111
-
Mapping of phenytoin-inducible cytochrome P450 immunoreactivity in the mouse central nervous system
-
Volk B, Hettmannsperger U, Papp T, Amelizad Z, Oesch F, Knoth R. Mapping of phenytoin-inducible cytochrome P450 immunoreactivity in the mouse central nervous system. Neurosci 1991;42:215-35.
-
(1991)
Neurosci
, vol.42
, pp. 215-235
-
-
Volk, B.1
Hettmannsperger, U.2
Papp, T.3
Amelizad, Z.4
Oesch, F.5
Knoth, R.6
-
12
-
-
0033947897
-
Regional and cellular distribution of CYP2D subfamily members in rat brain
-
Miksys S, Rao Y, Sellers EM, Kwan M, Mendis D, Tyndale RF. Regional and cellular distribution of CYP2D subfamily members in rat brain. Xenobiotica 2000;30:547-64.
-
(2000)
Xenobiotica
, vol.30
, pp. 547-564
-
-
Miksys, S.1
Rao, Y.2
Sellers, E.M.3
Kwan, M.4
Mendis, D.5
Tyndale, R.F.6
-
13
-
-
0030053243
-
Regional distribution of cytochrome P450 2D1 in the rat central nervous system
-
Norris PJ, Hardwick JP, Emson PC. Regional distribution of cytochrome P450 2D1 in the rat central nervous system. J Comp Neurol 1996;366:244-58.
-
(1996)
J Comp Neurol
, vol.366
, pp. 244-258
-
-
Norris, P.J.1
Hardwick, J.P.2
Emson, P.C.3
-
14
-
-
0027443245
-
Regiospecific expression of cytochrome P-450s and microsomal expoxide hydrolase in human brain tissue
-
Farin FM, Omiecinski CJ. Regiospecific expression of cytochrome P-450s and microsomal expoxide hydrolase in human brain tissue. J Toxicol Environ Health 1993;40:317-35.
-
(1993)
J Toxicol Environ Health
, vol.40
, pp. 317-335
-
-
Farin, F.M.1
Omiecinski, C.J.2
-
15
-
-
0030447180
-
Selective localisation of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera
-
Riedl AG, Watts PM, Edwards RJ, Boobis AR, Jenner P, Marsden CD. Selective localisation of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera. Brain Res 1996;743:324-8.
-
(1996)
Brain Res
, vol.743
, pp. 324-328
-
-
Riedl, A.G.1
Watts, P.M.2
Edwards, R.J.3
Boobis, A.R.4
Jenner, P.5
Marsden, C.D.6
-
16
-
-
0027359523
-
Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain
-
Schilter B, Omiecinski CJ. Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain. Mol Pharmacol 1993;44:990-6.
-
(1993)
Mol Pharmacol
, vol.44
, pp. 990-996
-
-
Schilter, B.1
Omiecinski, C.J.2
-
17
-
-
0031776805
-
Modulation of CYP1A2 enzyme activity by indoleamines: Inhibition by serotonin and tryptamine
-
Agundez JA, Gallardo L, Martinez C, Gervasini G, Benitez J. Modulation of CYP1A2 enzyme activity by indoleamines: inhibition by serotonin and tryptamine. Pharmacogenetics 1998;8:251-8.
-
(1998)
Pharmacogenetics
, vol.8
, pp. 251-258
-
-
Agundez, J.A.1
Gallardo, L.2
Martinez, C.3
Gervasini, G.4
Benitez, J.5
-
19
-
-
0032520750
-
Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain
-
McFadyen MCE, Melvin WT, Murray GI. Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain. Biochem Pharmacol 1998;55:825-30.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 825-830
-
-
McFadyen, M.C.E.1
Melvin, W.T.2
Murray, G.I.3
-
20
-
-
0030812372
-
Tumor-specific expression of cytochrome P450 CYP1B1
-
Murray GI, Taylor MC, McFadyen MC, McKay JA, Greenlee WF, Burke MD, et al. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 1997;57:3026-31.
-
(1997)
Cancer Res
, vol.57
, pp. 3026-3031
-
-
Murray, G.I.1
Taylor, M.C.2
McFadyen, M.C.3
McKay, J.A.4
Greenlee, W.F.5
Burke, M.D.6
-
21
-
-
0033988383
-
Human brain cytochrome P450 1B1: Immunohistochemical localization in human temporal lobe and induction by dimethylbenz(a)anthracene in astrocytoma cell line (MOG-GCCM)
-
Rieder CRM, Parsons RB, Fitch NJS, Williams AC, Ramsden DB. Human brain cytochrome P450 1B1: immunohistochemical localization in human temporal lobe and induction by dimethylbenz(a)anthracene in astrocytoma cell line (MOG-GCCM). Neurosci Lett 2000;278:177-80.
-
(2000)
Neurosci Lett
, vol.278
, pp. 177-180
-
-
Rieder, C.R.M.1
Parsons, R.B.2
Fitch, N.J.S.3
Williams, A.C.4
Ramsden, D.B.5
-
22
-
-
0031926298
-
Cytochrome P450 1B1 mRNA in the human central nervous system
-
Rieder CRM, Ramsden DB, Williams AC. Cytochrome P450 1B1 mRNA in the human central nervous system. Mol Pathol 1998;51:138-42.
-
(1998)
Mol Pathol
, vol.51
, pp. 138-142
-
-
Rieder, C.R.M.1
Ramsden, D.B.2
Williams, A.C.3
-
23
-
-
0035150691
-
In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues
-
Muskhelishvili L, Thomplson PA, Kusewitt DF, Wang C. In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. J Histochem Cytochem 2001;49:229-36.
-
(2001)
J Histochem Cytochem
, vol.49
, pp. 229-236
-
-
Muskhelishvili, L.1
Thomplson, P.A.2
Kusewitt, D.F.3
Wang, C.4
-
24
-
-
0025598114
-
Rat brain cytochromes P450: Catalytic, immunochemical properties and inducibility of multiple forms
-
Anandatheerthavarada HK, Shankar SK, Ravindranath V. Rat brain cytochromes P450: catalytic, immunochemical properties and inducibility of multiple forms. Brain Res 1990;536:339-43.
-
(1990)
Brain Res
, vol.536
, pp. 339-343
-
-
Anandatheerthavarada, H.K.1
Shankar, S.K.2
Ravindranath, V.3
-
25
-
-
0029583277
-
Localization and characterization of cytochrome P450 in the brain. In vivo and in vitro investigations on phenytoin- and phenobarbital-inducible forms
-
Volk B, Meyer RP, von Lintig F, Ibach B, Knoth R. Localization and characterization of cytochrome P450 in the brain. In vivo and in vitro investigations on phenytoin- and phenobarbital-inducible forms. Toxicol Lett 1995;82-83:655-62.
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 655-662
-
-
Volk, B.1
Meyer, R.P.2
Von Lintig, F.3
Ibach, B.4
Knoth, R.5
-
26
-
-
0035142758
-
Expression and localization of the CYP2B subfamily predominantly in neurones of rat brain
-
Rosenbrock H, Hagemeyer CE, Ditter M, Knoth R, Volk B. Expression and localization of the CYP2B subfamily predominantly in neurones of rat brain. J Neurochem 2001;76:332-40.
-
(2001)
J Neurochem
, vol.76
, pp. 332-340
-
-
Rosenbrock, H.1
Hagemeyer, C.E.2
Ditter, M.3
Knoth, R.4
Volk, B.5
-
27
-
-
0033972055
-
Multiple forms of cytochrome P450 and associated monooxygenase activities in human brain mitochondria
-
Bhagwat SV, Boyd MR, Ravindranath V. Multiple forms of cytochrome P450 and associated monooxygenase activities in human brain mitochondria. Biochem Pharmacol 2000;59:573-82.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 573-582
-
-
Bhagwat, S.V.1
Boyd, M.R.2
Ravindranath, V.3
-
28
-
-
0027244082
-
Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalitic activities
-
Bhamre S, Anandatheerathavarada HK, Shankar SK. Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalitic activities. Arch Biochem Biophys 1993;301:251-5.
-
(1993)
Arch Biochem Biophys
, vol.301
, pp. 251-255
-
-
Bhamre, S.1
Anandatheerathavarada, H.K.2
Shankar, S.K.3
-
29
-
-
0032791111
-
Human CYP2B6 expression, inducibility and catalytic activities
-
Gervot L, Rochat B, Gautier JC, Bohnenestengel F, Kroemer H, Berardinis VD, et al. Human CYP2B6 expression, inducibility and catalytic activities. Pharmacogenetics 1999;9:295-306.
-
(1999)
Pharmacogenetics
, vol.9
, pp. 295-306
-
-
Gervot, L.1
Rochat, B.2
Gautier, J.C.3
Bohnenestengel, F.4
Kroemer, H.5
Berardinis, V.D.6
-
30
-
-
0001078850
-
Nicotine-metabolizing CYP2B6 enzyme in human brain regions: Higher levels in smokers and smoking alcoholics
-
Miksys SL, Schoedel KA, Mash DC, Tyndale RF. Nicotine-metabolizing CYP2B6 enzyme in human brain regions: higher levels in smokers and smoking alcoholics. FASEB J 2001;15:A573.
-
(2001)
FASEB J
, vol.15
-
-
Miksys, S.L.1
Schoedel, K.A.2
Mash, D.C.3
Tyndale, R.F.4
-
31
-
-
0032195382
-
Immunohistochemical localization of cytochrome P450 enzymes 2C and 4A in the normal rat brain
-
Huang CB. Immunohistochemical localization of cytochrome P450 enzymes 2C and 4A in the normal rat brain. Clin Med J 1998;111:1007-12.
-
(1998)
Clin Med J
, vol.111
, pp. 1007-1012
-
-
Huang, C.B.1
-
32
-
-
0032167962
-
Cloning and expression of murine CYP2Cs and their ability to metabolize arachadonic acid
-
Luo G, Zeldin DC, Blaisdell JA, Hodgson E, Goldstein JA. Cloning and expression of murine CYP2Cs and their ability to metabolize arachadonic acid. Arch Biochem Biophys 1998;357:45-57.
-
(1998)
Arch Biochem Biophys
, vol.357
, pp. 45-57
-
-
Luo, G.1
Zeldin, D.C.2
Blaisdell, J.A.3
Hodgson, E.4
Goldstein, J.A.5
-
33
-
-
0034672795
-
Expression and distribution of CYP2C enzymes in rat basal ganglia
-
Riedl AG, Watts PM, Douek DC, Edwards RJ, Boobis AR, Rose S, et al. Expression and distribution of CYP2C enzymes in rat basal ganglia. Synapse 2000;38:392-402.
-
(2000)
Synapse
, vol.38
, pp. 392-402
-
-
Riedl, A.G.1
Watts, P.M.2
Douek, D.C.3
Edwards, R.J.4
Boobis, A.R.5
Rose, S.6
-
34
-
-
0032604625
-
Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs
-
Klose TS, Blaisdell JA, Goldstein JA. Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs. J Biochem Mol Toxicol 1999;13:289-95.
-
(1999)
J Biochem Mol Toxicol
, vol.13
, pp. 289-295
-
-
Klose, T.S.1
Blaisdell, J.A.2
Goldstein, J.A.3
-
35
-
-
0032101152
-
Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase
-
Watts PM, Riedl AG, Douek DC, Edwards RJ, Boobis AR, Jenner P, et al. Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase. Neurosci 1998;86:511-9.
-
(1998)
Neurosci
, vol.86
, pp. 511-519
-
-
Watts, P.M.1
Riedl, A.G.2
Douek, D.C.3
Edwards, R.J.4
Boobis, A.R.5
Jenner, P.6
-
36
-
-
0033586335
-
Expression and localization of CYP2D enzymes in rat basal ganglia
-
Riedl AG, Watts PM, Edwards RJ, Schulz-Utermoehl T, Boobis AR, Jenner P, et al. Expression and localization of CYP2D enzymes in rat basal ganglia. Brain Res 1999;822:175-91.
-
(1999)
Brain Res
, vol.822
, pp. 175-191
-
-
Riedl, A.G.1
Watts, P.M.2
Edwards, R.J.3
Schulz-Utermoehl, T.4
Boobis, A.R.5
Jenner, P.6
-
37
-
-
0025779409
-
Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): Potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6
-
Tyndale RF, Sunahara R, Inaba T, Kalow W, Gonzalez FJ, Niznik HB. Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6. Mol Pharmacol 1991;40:63-8.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 63-68
-
-
Tyndale, R.F.1
Sunahara, R.2
Inaba, T.3
Kalow, W.4
Gonzalez, F.J.5
Niznik, H.B.6
-
38
-
-
0025356936
-
Regional distribution of ethanol-inducible cytochrome P450 IIEI in the rat central nervous system
-
Hansson T, Tindberg N, Ingelman-Sundberg M, Kohler C. Regional distribution of ethanol-inducible cytochrome P450 IIEI in the rat central nervous system. Neuroscience 1990;34:451-63.
-
(1990)
Neuroscience
, vol.34
, pp. 451-463
-
-
Hansson, T.1
Tindberg, N.2
Ingelman-Sundberg, M.3
Kohler, C.4
-
39
-
-
0027889530
-
Immunohistochemical demonstration of ethanol-inducible P450 2E1 in rat brain
-
Sohda T, Shimizu M, Kamimura S, Okumura M. Immunohistochemical demonstration of ethanol-inducible P450 2E1 in rat brain. Alcohol Alcohol Suppl 1993;1B:69-75.
-
(1993)
Alcohol Alcohol Suppl
, vol.1 B
, pp. 69-75
-
-
Sohda, T.1
Shimizu, M.2
Kamimura, S.3
Okumura, M.4
-
40
-
-
0029823019
-
Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
-
Tindberg N, Ingelman-Sundberg M. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system. J Neurochem 1996;67:2066-73.
-
(1996)
J Neurochem
, vol.67
, pp. 2066-2073
-
-
Tindberg, N.1
Ingelman-Sundberg, M.2
-
41
-
-
0031566260
-
Identification of cytochrome P450 2E1 in rat brain
-
Yoo M, Ryu HM, Shin SW, Yun CH, Lee SC, Ji YM, et al. Identification of cytochrome P450 2E1 in rat brain. Biochem Biophys Res Commun 1997;231:254-6.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 254-256
-
-
Yoo, M.1
Ryu, H.M.2
Shin, S.W.3
Yun, C.H.4
Lee, S.C.5
Ji, Y.M.6
-
42
-
-
0033958619
-
Cytochrome P4502E (CYP2E) in brain: Constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization
-
Upadhya SC, Tirumalai PS, Boyd MR, Mori T, Ravindranath V. Cytochrome P4502E (CYP2E) in brain: constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization. Arch Biochem Biophys 2000;373:23-34.
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 23-34
-
-
Upadhya, S.C.1
Tirumalai, P.S.2
Boyd, M.R.3
Mori, T.4
Ravindranath, V.5
-
43
-
-
0031577540
-
Expression of CYP2E1 during embryogenesis and fetogenesis in human cephalic tissues: Implications for the fetal alcohol syndrome
-
Boutelet-Bochan H, Huang Y, Juchau MR. Expression of CYP2E1 during embryogenesis and fetogenesis in human cephalic tissues: implications for the fetal alcohol syndrome. Biochem Biophys Res Comm 1997;238:443-7.
-
(1997)
Biochem Biophys Res Comm
, vol.238
, pp. 443-447
-
-
Boutelet-Bochan, H.1
Huang, Y.2
Juchau, M.R.3
-
44
-
-
0033060750
-
Catalytic activity and quantitation of cytochrome P450 2E1 in prenatal human brain
-
Brzezinski MR, Boutelet-Bochan H, Person RE, Fantel AG, Juchau MR. Catalytic activity and quantitation of cytochrome P450 2E1 in prenatal human brain. J Pharmacol Exp Ther 1999;289:1648-53.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1648-1653
-
-
Brzezinski, M.R.1
Boutelet-Bochan, H.2
Person, R.E.3
Fantel, A.G.4
Juchau, M.R.5
-
45
-
-
0035048387
-
Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β-hydroxylase
-
Dai D, Bai R, Hodgson E, Rose RL. Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β-hydroxylase. J Biochem Mol Toxicol 2001;15:90-9.
-
(2001)
J Biochem Mol Toxicol
, vol.15
, pp. 90-99
-
-
Dai, D.1
Bai, R.2
Hodgson, E.3
Rose, R.L.4
-
47
-
-
17744397194
-
Genomic organization of the human CYP3A locus: Identification of a new, inducible CYP3A gene
-
Gellner K, Eiselt R, Hustert E, Arnold H, Koch I, Haberl M, et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. Pharmacogenetics 2001;11:111-21.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 111-121
-
-
Gellner, K.1
Eiselt, R.2
Hustert, E.3
Arnold, H.4
Koch, I.5
Haberl, M.6
-
49
-
-
0029610431
-
cDNA cloning of three new forms of rat brain cytochrome P450 belonging to the CYP4F subfamily
-
Kawashima H, Strobel HW. cDNA cloning of three new forms of rat brain cytochrome P450 belonging to the CYP4F subfamily. Biochem Biophys Res Comm 1995;217:1137-44.
-
(1995)
Biochem Biophys Res Comm
, vol.217
, pp. 1137-1144
-
-
Kawashima, H.1
Strobel, H.W.2
-
51
-
-
0025369528
-
Presence of functional cytochrome P-450 on isolated rat hepatocyte plasma membrane
-
Loeper J, Descatoire V, Maurice M, Beaune P, Feldmann G, Larrey D, et al. Presence of functional cytochrome P-450 on isolated rat hepatocyte plasma membrane. Hepatology 1990;11:850-8.
-
(1990)
Hepatology
, vol.11
, pp. 850-858
-
-
Loeper, J.1
Descatoire, V.2
Maurice, M.3
Beaune, P.4
Feldmann, G.5
Larrey, D.6
-
52
-
-
0030630618
-
Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis
-
Robin M, LeRoy M, Descatoire V, Pessayre D. Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis. J Hepatology 1997;26:23-30.
-
(1997)
J Hepatology
, vol.26
, pp. 23-30
-
-
Robin, M.1
LeRoy, M.2
Descatoire, V.3
Pessayre, D.4
-
53
-
-
0026503184
-
Presence of functionally active cytochrome P-450IIEI in the plasma membrane of rat hepatocytes
-
Wu D, Cederbaum AI. Presence of functionally active cytochrome P-450IIEI in the plasma membrane of rat hepatocytes. Hepatology 1992;15:515-24.
-
(1992)
Hepatology
, vol.15
, pp. 515-524
-
-
Wu, D.1
Cederbaum, A.I.2
-
54
-
-
0024267599
-
Hepatic mitochondrial coumarin 7-hydroxylase: Comparison with the microsomal enzyme
-
Honkakoski P, Kojo A, Raunio H, Pasanen M, Juvonen R, Lang MA. Hepatic mitochondrial coumarin 7-hydroxylase: comparison with the microsomal enzyme. Arch Biochem Biophys 1988;267:558-67.
-
(1988)
Arch Biochem Biophys
, vol.267
, pp. 558-567
-
-
Honkakoski, P.1
Kojo, A.2
Raunio, H.3
Pasanen, M.4
Juvonen, R.5
Lang, M.A.6
-
55
-
-
0030587579
-
Enzyme-specific transport of rat liver cytochrome P450 to the golgi apparatus
-
Neve EPA, Eliasson E, Pronzato MA, Albano E, Marinari U, Ingelman-Sundberg M. Enzyme-specific transport of rat liver cytochrome P450 to the golgi apparatus. Arch Biochem Biophys 1996;333:459-65.
-
(1996)
Arch Biochem Biophys
, vol.333
, pp. 459-465
-
-
Neve, E.P.A.1
Eliasson, E.2
Pronzato, M.A.3
Albano, E.4
Marinari, U.5
Ingelman-Sundberg, M.6
-
56
-
-
0028905014
-
Cytochrome P4502B follows a vesicular route to the plasma membrane in cultured rat hepatocytes
-
Robin MA, Maratrat M, Loeper J, Durand-Schneider AM, Tinel M, Ballet F, et al. Cytochrome P4502B follows a vesicular route to the plasma membrane in cultured rat hepatocytes. Gastroenterology 1995;108:1110-23.
-
(1995)
Gastroenterology
, vol.108
, pp. 1110-1123
-
-
Robin, M.A.1
Maratrat, M.2
Loeper, J.3
Durand-Schneider, A.M.4
Tinel, M.5
Ballet, F.6
-
57
-
-
0022486795
-
Subcellular distribution of cytochrome P-450 in the brain
-
Walther B, Ghersi-Egea JF, Minn A, Siest G. Subcellular distribution of cytochrome P-450 in the brain. Brain Res 1986;375:338-44.
-
(1986)
Brain Res
, vol.375
, pp. 338-344
-
-
Walther, B.1
Ghersi-Egea, J.F.2
Minn, A.3
Siest, G.4
-
58
-
-
0029018854
-
Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord: Induction, immunological characterization and immunocytochemical localization
-
Bhagwat SV, Leelavathi BC, Shankar SK, Boyd MR, Ravindranath V. Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord: induction, immunological characterization and immunocytochemical localization. Neuroscience 1995;68:593-601.
-
(1995)
Neuroscience
, vol.68
, pp. 593-601
-
-
Bhagwat, S.V.1
Leelavathi, B.C.2
Shankar, S.K.3
Boyd, M.R.4
Ravindranath, V.5
-
59
-
-
0025369152
-
Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: The olfactory bulb and the mitochondrial fraction have high levels of activity
-
Iscan M, Reuhl K, Weiss R, Maines MD. Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: the olfactory bulb and the mitochondrial fraction have high levels of activity. Biochem Biophys Res Comm 1990;169:858-63.
-
(1990)
Biochem Biophys Res Comm
, vol.169
, pp. 858-863
-
-
Iscan, M.1
Reuhl, K.2
Weiss, R.3
Maines, M.D.4
-
60
-
-
0023135191
-
Ethoxyresorufin O-deethylase activity in rat brain subcellular fraction
-
Walther B, Ghersi-Egea JF, Jayyosi Z, Minn A, Siest G. Ethoxyresorufin O-deethylase activity in rat brain subcellular fraction. Neurosci Lett 1987;76:58-62.
-
(1987)
Neurosci Lett
, vol.76
, pp. 58-62
-
-
Walther, B.1
Ghersi-Egea, J.F.2
Jayyosi, Z.3
Minn, A.4
Siest, G.5
-
64
-
-
0029959286
-
Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18 catalyzing imipramine N-demethylation
-
Kawashima H, Sequeira DJ, Nelson DR, Strobel HW. Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18 catalyzing imipramine N-demethylation. J Biol Chem 1996;271:28176-89.
-
(1996)
J Biol Chem
, vol.271
, pp. 28176-28189
-
-
Kawashima, H.1
Sequeira, D.J.2
Nelson, D.R.3
Strobel, H.W.4
-
65
-
-
0027515851
-
A novel P450 expressed at the high level in rat brain
-
Komori M. A novel P450 expressed at the high level in rat brain. Biochem Biophys Res Comm 1993;196:721-8.
-
(1993)
Biochem Biophys Res Comm
, vol.196
, pp. 721-728
-
-
Komori, M.1
-
66
-
-
0031574143
-
Expression of four rat CYP2D isoforms in saccharomyces cerevisiae and their catalytic specificity
-
Wan J, Imaoka S, Chow T, Hiroi T, Yabusaki Y, Funae Y. Expression of four rat CYP2D isoforms in saccharomyces cerevisiae and their catalytic specificity. Arch Biochem Biophys 1997;348:383-90.
-
(1997)
Arch Biochem Biophys
, vol.348
, pp. 383-390
-
-
Wan, J.1
Imaoka, S.2
Chow, T.3
Hiroi, T.4
Yabusaki, Y.5
Funae, Y.6
-
67
-
-
0023552253
-
Inducibility of rat brain drug-metabolizing enzymes
-
Ghersi-Egea JF, Walther B, Perrin R, Minn A, Siest G. Inducibility of rat brain drug-metabolizing enzymes. Eur J Drug Metab Pharmacokinet 1987;12:263-5.
-
(1987)
Eur J Drug Metab Pharmacokinet
, vol.12
, pp. 263-265
-
-
Ghersi-Egea, J.F.1
Walther, B.2
Perrin, R.3
Minn, A.4
Siest, G.5
-
68
-
-
0033846723
-
Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers
-
Schilter B, Anderson MR, Acharya C, Omiecinski CJ. Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers. J Pharmacol Exp Ther 2000;294:916-22.
-
(2000)
J Pharmacol Exp Ther
, vol.294
, pp. 916-922
-
-
Schilter, B.1
Anderson, M.R.2
Acharya, C.3
Omiecinski, C.J.4
-
69
-
-
0034799622
-
Effect of cytochrome P450 1A induction on oxidative damage in rat brain
-
Liu L, Bridges RJ, Eyer CL. Effect of cytochrome P450 1A induction on oxidative damage in rat brain. Mol Cell Biochem 2001;223:89-94.
-
(2001)
Mol Cell Biochem
, vol.223
, pp. 89-94
-
-
Liu, L.1
Bridges, R.J.2
Eyer, C.L.3
-
70
-
-
0028042339
-
Cytochrome P450 in rat astrocytes in vivo and in vitro: Intracellular localization and induction by phenytoin
-
Kempermann G, Knoth R, Gebicke-Haerter PJ, Stolz BJ, Volk B. Cytochrome P450 in rat astrocytes in vivo and in vitro: intracellular localization and induction by phenytoin. J Neurosci Res 1994;39:576-88.
-
(1994)
J Neurosci Res
, vol.39
, pp. 576-588
-
-
Kempermann, G.1
Knoth, R.2
Gebicke-Haerter, P.J.3
Stolz, B.J.4
Volk, B.5
-
71
-
-
0032775358
-
Testosterone metabolism in rat brain is differentially enhanced by phentoin-inducible cytochrome P450 isoforms
-
Rosenbrock H, Hagemeyer CE, Singec I, Knoth R, Volk B. Testosterone metabolism in rat brain is differentially enhanced by phentoin-inducible cytochrome P450 isoforms. J Neuroendocrinol 1999;11:597-604.
-
(1999)
J Neuroendocrinol
, vol.11
, pp. 597-604
-
-
Rosenbrock, H.1
Hagemeyer, C.E.2
Singec, I.3
Knoth, R.4
Volk, B.5
-
72
-
-
0030858099
-
Regulation of expression of cytochrome P-450 2D mRNA in rat brain with steroid hormones
-
Baum LO, Strobel HW. Regulation of expression of cytochrome P-450 2D mRNA in rat brain with steroid hormones. Brain Res 1997;765:67-73.
-
(1997)
Brain Res
, vol.765
, pp. 67-73
-
-
Baum, L.O.1
Strobel, H.W.2
-
73
-
-
0027513539
-
Induction of brain cytochrome P450IIEI by chronic ethanol treatment
-
Anandatheerthavarada HK, Shankar SK, Bhamre S, Boyd MR, Song B-J, Ravindranath V. Induction of brain cytochrome P450IIEI by chronic ethanol treatment. Brain Res 1993;601:279-85.
-
(1993)
Brain Res
, vol.601
, pp. 279-285
-
-
Anandatheerthavarada, H.K.1
Shankar, S.K.2
Bhamre, S.3
Boyd, M.R.4
Song, B.-J.5
Ravindranath, V.6
-
74
-
-
0028856361
-
Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes
-
Montoliu C, Sancho-Tello M, Azorin I, Burgal M, Valles S, Renau-Piqueras J, et al. Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes. J Neurochem 1995;65:2561-70.
-
(1995)
J Neurochem
, vol.65
, pp. 2561-2570
-
-
Montoliu, C.1
Sancho-Tello, M.2
Azorin, I.3
Burgal, M.4
Valles, S.5
Renau-Piqueras, J.6
-
75
-
-
0027946058
-
Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic alcohol consumption
-
Montoliu C, Valles S, Renau-Piqueras J, Guerri C. Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: effect of chronic alcohol consumption. J Neurochem 1994;63:1855-62.
-
(1994)
J Neurochem
, vol.63
, pp. 1855-1862
-
-
Montoliu, C.1
Valles, S.2
Renau-Piqueras, J.3
Guerri, C.4
-
76
-
-
0028118901
-
Effect of ethanol on cytochrome P450 in the rat brain
-
Warner M, Gustafsson JA. Effect of ethanol on cytochrome P450 in the rat brain. Proc Natl Acad Sci U S A 1994;91:1019-23.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 1019-1023
-
-
Warner, M.1
Gustafsson, J.A.2
-
77
-
-
0035501355
-
Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain
-
Schoedel KA, Sellers EM, Tyndale RF. Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain. Biochem Pharmacol 2001;62:1025-36.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1025-1036
-
-
Schoedel, K.A.1
Sellers, E.M.2
Tyndale, R.F.3
-
78
-
-
0020616457
-
Widespread neuroanatomical damage and learning deficits following chronic alcohol consumption or vitamin-B1 (thiamine) deficiency in rats
-
Irle E, Markowitsch HJ. Widespread neuroanatomical damage and learning deficits following chronic alcohol consumption or vitamin-B1 (thiamine) deficiency in rats. Behav Brain Res 1983;9:277-94.
-
(1983)
Behav Brain Res
, vol.9
, pp. 277-294
-
-
Irle, E.1
Markowitsch, H.J.2
-
79
-
-
0027213570
-
Differential effect of chronic nicotine administration on brain cytochrome P4501A1/2 and P4502E1
-
Anandatheervarada HK, Williams JF, Wecker L. Differential effect of chronic nicotine administration on brain cytochrome P4501A1/2 and P4502E1. Biochem Biophys Res Commun 1993;194:312-8.
-
(1993)
Biochem Biophys Res Commun
, vol.194
, pp. 312-318
-
-
Anandatheervarada, H.K.1
Williams, J.F.2
Wecker, L.3
-
80
-
-
0027190772
-
The chronic administration of nicotine induces cytochrome P450 in rat brain
-
Anandatheerthavarada HK, WIlliams JF, Wecker L. The chronic administration of nicotine induces cytochrome P450 in rat brain. J Neurochem 1993;60:1941-4.
-
(1993)
J Neurochem
, vol.60
, pp. 1941-1944
-
-
Anandatheerthavarada, H.K.1
Williams, J.F.2
Wecker, L.3
-
81
-
-
0031831381
-
Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines
-
Hecht SS. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 1998;11:559-603.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 559-603
-
-
Hecht, S.S.1
-
82
-
-
0034092057
-
Identification of the human cytochromes P450 involved in the oxidative metabolism of "Ecstasy"-related designer drugs
-
Kreth K, Kovar K, Schwab M, Zanger UM. Identification of the human cytochromes P450 involved in the oxidative metabolism of "Ecstasy"-related designer drugs. Biochem Pharmacol 2000;59:1563-71.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1563-1571
-
-
Kreth, K.1
Kovar, K.2
Schwab, M.3
Zanger, U.M.4
-
83
-
-
0028069445
-
Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats
-
Kumagai Y, Lin LY, Hiratsuka A, Narimatsu S, Suzuki T, Yamada H, et al. Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats. Mol Pharmacol 1994;45:359-65.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 359-365
-
-
Kumagai, Y.1
Lin, L.Y.2
Hiratsuka, A.3
Narimatsu, S.4
Suzuki, T.5
Yamada, H.6
-
84
-
-
0033695681
-
Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver
-
Pellinen P, Kulmala L, Konttila J, Auriola S, Pasanen M, Juvonen R. Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver. Arch Toxicol 2000;74:511-20.
-
(2000)
Arch Toxicol
, vol.74
, pp. 511-520
-
-
Pellinen, P.1
Kulmala, L.2
Konttila, J.3
Auriola, S.4
Pasanen, M.5
Juvonen, R.6
-
85
-
-
0028245664
-
Inactivation of cytohromes P450 2B protects against cocaine-mediated toxicity
-
Poet TS, Brendel K, Halpert JR. Inactivation of cytohromes P450 2B protects against cocaine-mediated toxicity. Toxicol Appl Pharmacol 1994;126:26-32.
-
(1994)
Toxicol Appl Pharmacol
, vol.126
, pp. 26-32
-
-
Poet, T.S.1
Brendel, K.2
Halpert, J.R.3
-
86
-
-
0035887395
-
Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts
-
Albores A, Ortega-Mantilla G, Sierra-Santoyo A, Cebrian ME, Munoz-Sanchez JL, Calderon-Salinas JV, et al. Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts. Toxicol Lett 2001;124:1-10.
-
(2001)
Toxicol Lett
, vol.124
, pp. 1-10
-
-
Albores, A.1
Ortega-Mantilla, G.2
Sierra-Santoyo, A.3
Cebrian, M.E.4
Munoz-Sanchez, J.L.5
Calderon-Salinas, J.V.6
-
87
-
-
0026625806
-
Reconstitution of the brain mixed function oxidase system: Purification of NADPH-cytochrome P450 reductase and partial purification of cytochrome P450 from whole brain
-
Bergh AF, Strobel HW. Reconstitution of the brain mixed function oxidase system: purification of NADPH-cytochrome P450 reductase and partial purification of cytochrome P450 from whole brain. J Neurochem 1992;59:575-81.
-
(1992)
J Neurochem
, vol.59
, pp. 575-581
-
-
Bergh, A.F.1
Strobel, H.W.2
-
88
-
-
0025123839
-
Distribution of cytochrome P450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions, and isolated cerebral microvessels
-
Perrin R, Minn A, Gheris-Egea JF, Grassiot MC, Siest G. Distribution of cytochrome P450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions, and isolated cerebral microvessels. Biochem Pharmacol 1990;40:2145-51.
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 2145-2151
-
-
Perrin, R.1
Minn, A.2
Gheris-Egea, J.F.3
Grassiot, M.C.4
Siest, G.5
-
89
-
-
0027473732
-
Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain
-
Ghersi-Egea JF, Perrin R, Leininger-Muller B, Jeandel MCGC, Floquet J, Cuny G, et al. Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain. Biochem Pharmacol 1993;45:647-58.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 647-658
-
-
Ghersi-Egea, J.F.1
Perrin, R.2
Leininger-Muller, B.3
Jeandel, M.C.G.C.4
Floquet, J.5
Cuny, G.6
-
90
-
-
0024315016
-
Xenobiotic metabolism in human brain-presence of cytochrome P-450 and associated mono-oxygenases
-
Ravindranath V, Anandatheerthavarada HK, Shankar SK. Xenobiotic metabolism in human brain-presence of cytochrome P-450 and associated mono-oxygenases. Brain Res 1989;496:331-5.
-
(1989)
Brain Res
, vol.496
, pp. 331-335
-
-
Ravindranath, V.1
Anandatheerthavarada, H.K.2
Shankar, S.K.3
-
91
-
-
0032809128
-
Characterization of cytochrome P-450 2D1 activity in rat brain; high-affinity kinetics for dextromethorphan
-
Tyndale RF, Li Y, Li N-Y, Messina E, Miksys S, Sellers EM. Characterization of cytochrome P-450 2D1 activity in rat brain; high-affinity kinetics for dextromethorphan. Drug Metab Dispos 1999;27:924-30.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 924-930
-
-
Tyndale, R.F.1
Li, Y.2
Li, N.-Y.3
Messina, E.4
Miksys, S.5
Sellers, E.M.6
-
92
-
-
0032211208
-
Isolation of partially purified P450 2D18 and characterization of activity toward the tricyclic antidepressants imipramine and desipramine
-
Thompson CM, Kawashima H, Strobel HW. Isolation of partially purified P450 2D18 and characterization of activity toward the tricyclic antidepressants imipramine and desipramine. Arch Biochem Biophys 1998;359:115-21.
-
(1998)
Arch Biochem Biophys
, vol.359
, pp. 115-121
-
-
Thompson, C.M.1
Kawashima, H.2
Strobel, H.W.3
-
93
-
-
0032832513
-
Cytochrome P450 (P450) isoenzyme specific dealkylation of alkoxyresorufins in rat brain microsomes
-
Dhawan A, Parmar D, Dayal M, Seth PK. Cytochrome P450 (P450) isoenzyme specific dealkylation of alkoxyresorufins in rat brain microsomes. Mol Cell Biochem 1999;200:169-76.
-
(1999)
Mol Cell Biochem
, vol.200
, pp. 169-176
-
-
Dhawan, A.1
Parmar, D.2
Dayal, M.3
Seth, P.K.4
-
94
-
-
0031790097
-
Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain
-
Parmar D, Dhawan A, Seth PK. Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain. Mol Cell Biochem 1998;189:201-5.
-
(1998)
Mol Cell Biochem
, vol.189
, pp. 201-205
-
-
Parmar, D.1
Dhawan, A.2
Seth, P.K.3
-
95
-
-
0028876877
-
Dextromethorphan O-demethylase activity in rat brain microsomes
-
Jolivalt C, Minn A, Vincent-Viry M, Galteau M-M, Siest G. Dextromethorphan O-demethylase activity in rat brain microsomes. Neurosci Lett 1995;187:65-8.
-
(1995)
Neurosci Lett
, vol.187
, pp. 65-68
-
-
Jolivalt, C.1
Minn, A.2
Vincent-Viry, M.3
Galteau, M.-M.4
Siest, G.5
-
96
-
-
0034645927
-
Cytochrome P-450 activities in human and rat brain microsomes
-
Voirol P, Jonzier-Perey M, Porchet F, Reymond MJ, Janzer RC, Bouras C, et al. Cytochrome P-450 activities in human and rat brain microsomes. Brain Res 2000;855:235-43.
-
(2000)
Brain Res
, vol.855
, pp. 235-243
-
-
Voirol, P.1
Jonzier-Perey, M.2
Porchet, F.3
Reymond, M.J.4
Janzer, R.C.5
Bouras, C.6
-
97
-
-
0033848496
-
The 1′-hydroxylation of Rac-bufuralol by rat brain microsomes
-
Coleman T, Spellman EF, Rostami-Hodjegan A, Lennard MS, Tucker GT. The 1′-hydroxylation of Rac-bufuralol by rat brain microsomes. Drug Metab Dispos 2000;28:1094-9.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1094-1099
-
-
Coleman, T.1
Spellman, E.F.2
Rostami-Hodjegan, A.3
Lennard, M.S.4
Tucker, G.T.5
-
98
-
-
0032940062
-
Biphasic kinetics of imipramine N-oxidation in rat brain microsomes
-
Narimatsu S, Yamamoto S, Koitabashi T, Kato R, Masubuchi Y, Suzuki T, et al. Biphasic kinetics of imipramine N-oxidation in rat brain microsomes. Biol Pharm Bull 1999;22:253-6.
-
(1999)
Biol Pharm Bull
, vol.22
, pp. 253-256
-
-
Narimatsu, S.1
Yamamoto, S.2
Koitabashi, T.3
Kato, R.4
Masubuchi, Y.5
Suzuki, T.6
-
99
-
-
0026745577
-
Different regiospecificity in the hydroxylation of the antidepressant desmethylimipramine between rat brain and liver
-
Hansson T, vonBahr C, Marklund M, Svensson JO, Ingelman-Sundberg M, Lundstrom J. Different regiospecificity in the hydroxylation of the antidepressant desmethylimipramine between rat brain and liver. Pharmacol Toxicol 1992;71:416-9.
-
(1992)
Pharmacol Toxicol
, vol.71
, pp. 416-419
-
-
Hansson, T.1
VonBahr, C.2
Marklund, M.3
Svensson, J.O.4
Ingelman-Sundberg, M.5
Lundstrom, J.6
-
100
-
-
0031030608
-
Metabolites of nicotine in rat brain after peripheral nicotine administration
-
Crooks PA, Li M, Dwoskin LP. Metabolites of nicotine in rat brain after peripheral nicotine administration. Drug Metab Dispos 1997;25:47-54.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 47-54
-
-
Crooks, P.A.1
Li, M.2
Dwoskin, L.P.3
-
101
-
-
0031413947
-
Metabolism of (-)-(S)-nicotine by guinea pig and rat brain: Identification of cotinine
-
Jacob P 3rd, Ulgen M, Gorrod JW. Metabolism of (-)-(S)-nicotine by guinea pig and rat brain: identification of cotinine. Eur J Drug Metab Pharmacokinet 1997;22:391-4.
-
(1997)
Eur J Drug Metab Pharmacokinet
, vol.22
, pp. 391-394
-
-
Jacob P. III1
Ulgen, M.2
Gorrod, J.W.3
-
102
-
-
0030967588
-
Brain microsomal metabolism of phencyclidine in male and female rats
-
Laurenzana EM, Owens SM. Brain microsomal metabolism of phencyclidine in male and female rats. Brain Res 1997;756:256-65.
-
(1997)
Brain Res
, vol.756
, pp. 256-265
-
-
Laurenzana, E.M.1
Owens, S.M.2
-
103
-
-
0025342558
-
Morphine formation from codeine in rat brain: A possible mechanism of codeine analgesia
-
Chen AR, Irvine RJ, Bochner F, Somogyi AA. Morphine formation from codeine in rat brain: a possible mechanism of codeine analgesia. Life Sciences 1990;46:1067-74.
-
(1990)
Life Sciences
, vol.46
, pp. 1067-1074
-
-
Chen, A.R.1
Irvine, R.J.2
Bochner, F.3
Somogyi, A.A.4
-
104
-
-
0026731379
-
Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes
-
Lin LY, Kumagai Y, Cho AK. Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes. Chem Res Toxicol 1992;5:401-6.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 401-406
-
-
Lin, L.Y.1
Kumagai, Y.2
Cho, A.K.3
-
105
-
-
0024591188
-
Activation and degradation of the phosphorothionate insecticides parathion and EPN by rat brain
-
Forsyth CS, Chambers JE. Activation and degradation of the phosphorothionate insecticides parathion and EPN by rat brain. Biochem Pharmacol 1989;38:1597-603.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 1597-1603
-
-
Forsyth, C.S.1
Chambers, J.E.2
-
106
-
-
0027258089
-
Progress in psychiatry (1)
-
Michels R, Marzuk PM. Progress in psychiatry (1) [review]. N Engl J Med 1993;329:552-60.
-
(1993)
N Engl J Med
, vol.329
, pp. 552-560
-
-
Michels, R.1
Marzuk, P.M.2
-
107
-
-
0002255855
-
Debrisoquine.sparteine monooxygenase and other P-450s in brain
-
Kalow W, editor. New York: Pergamon Press
-
Kalow W, Tyndale RF. Debrisoquine.sparteine monooxygenase and other P-450s in brain. In: Kalow W, editor. Pharmacogenetics of drug metabolism. New York: Pergamon Press; 1992. p. 649-56.
-
(1992)
Pharmacogenetics of Drug Metabolism
, pp. 649-656
-
-
Kalow, W.1
Tyndale, R.F.2
-
108
-
-
0032980471
-
Metabolism, pharmacogenetics, and metabolic drug-drug interactions of antipsychotic drugs
-
Fang J, Gorrod JW. Metabolism, pharmacogenetics, and metabolic drug-drug interactions of antipsychotic drugs. Cell Mol Neurobiol 1999;19:491-510.
-
(1999)
Cell Mol Neurobiol
, vol.19
, pp. 491-510
-
-
Fang, J.1
Gorrod, J.W.2
-
109
-
-
0344110152
-
Pharmacokinetics of selective serotonin reuptake inhibitors
-
Hiemke C, Hartter S. Pharmacokinetics of selective serotonin reuptake inhibitors. Pharmacol Ther 2000;85:11-28.
-
(2000)
Pharmacol Ther
, vol.85
, pp. 11-28
-
-
Hiemke, C.1
Hartter, S.2
-
111
-
-
0026685066
-
Cytochrome P450 in the brain. Potential evolutionary and therapeutic relevance of localization of drug-metabolizing enzymes
-
Britto MR, Wedlund PJ. Cytochrome P450 in the brain. Potential evolutionary and therapeutic relevance of localization of drug-metabolizing enzymes. Drug Metabol Dispos 1992;20:446-50.
-
(1992)
Drug Metabol Dispos
, vol.20
, pp. 446-450
-
-
Britto, M.R.1
Wedlund, P.J.2
-
114
-
-
0030951095
-
Tryptamine: A possible endogenous substrate for CYP2D6
-
Martinez C, Agundez JAG, Gervasini G, Martin R, Benitez J. Tryptamine: a possible endogenous substrate for CYP2D6. Pharmacogenetics 1997;7:85-93.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 85-93
-
-
Martinez, C.1
Agundez, J.A.G.2
Gervasini, G.3
Martin, R.4
Benitez, J.5
-
115
-
-
0033846716
-
Recombinant cytochrome P450 2D18 metabolism of dopamine and arachadonic acid
-
Thompson CM, Capdevila JH, Strobel HW. Recombinant cytochrome P450 2D18 metabolism of dopamine and arachadonic acid. J Pharmacol Exper Ther 2000;294:1120-30.
-
(2000)
J Pharmacol Exper Ther
, vol.294
, pp. 1120-1130
-
-
Thompson, C.M.1
Capdevila, J.H.2
Strobel, H.W.3
-
116
-
-
0035877348
-
Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substanti nigra: A new metabolic pathway?
-
Nissbrandt H, Bergquist F, Jonason J, Engberg F. Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substanti nigra: a new metabolic pathway? Synapse 2001;40:294-301.
-
(2001)
Synapse
, vol.40
, pp. 294-301
-
-
Nissbrandt, H.1
Bergquist, F.2
Jonason, J.3
Engberg, F.4
-
118
-
-
0034091750
-
CYP2D6 ultrarapid metabolizer genotype as a potential modifier of smoking behaviour
-
Saarikoski ST, Sata F, Husgafvel-Pursiainen K, Rautalahti M, Haukka J, Impivaara O, et al. CYP2D6 ultrarapid metabolizer genotype as a potential modifier of smoking behaviour. Pharmacogenetics 2000;10:5-10.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 5-10
-
-
Saarikoski, S.T.1
Sata, F.2
Husgafvel-Pursiainen, K.3
Rautalahti, M.4
Haukka, J.5
Impivaara, O.6
-
119
-
-
0029050430
-
Frequency of a specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson disease
-
Akhmedova SN, Pushnova EA, Yakimovsky AF, Avtonomov VV, Schwartz EI. Frequency of a specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson disease. Biochem Mol Med 1995;54:88-90.
-
(1995)
Biochem Mol Med
, vol.54
, pp. 88-90
-
-
Akhmedova, S.N.1
Pushnova, E.A.2
Yakimovsky, A.F.3
Avtonomov, V.V.4
Schwartz, E.I.5
-
120
-
-
0027330416
-
Variant cytochrome P450 CYP2D6 alleleic frequencies in Parkinson's disease
-
Kurth MC, Kurth JH. Variant cytochrome P450 CYP2D6 alleleic frequencies in Parkinson's disease. Am J Med Genet 1993;48:166-8.
-
(1993)
Am J Med Genet
, vol.48
, pp. 166-168
-
-
Kurth, M.C.1
Kurth, J.H.2
-
121
-
-
0027200680
-
A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease
-
Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y. A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease. J Biochem 1993;114:263-6.
-
(1993)
J Biochem
, vol.114
, pp. 263-266
-
-
Tsuneoka, Y.1
Matsuo, Y.2
Iwahashi, K.3
Takeuchi, H.4
Ichikawa, Y.5
-
122
-
-
0027172563
-
Sparteine oxidation by hepatic cytochrome P-450 in patients with Parkinson's disease
-
Yoshino H, Hattori Y, Imai H, Narabayashi H, Chiba K. Sparteine oxidation by hepatic cytochrome P-450 in patients with Parkinson's disease [In Japanese]. Rinsho Shinkeigaku 1993;33:261-5.
-
(1993)
Rinsho Shinkeigaku
, vol.33
, pp. 261-265
-
-
Yoshino, H.1
Hattori, Y.2
Imai, H.3
Narabayashi, H.4
Chiba, K.5
-
123
-
-
0032609801
-
P450 and heme oxygenase enzymes in the basal ganglia and their roles in Parkinson's disease
-
Riedl AG, Watts PM, Brown CT, Jenner P. P450 and heme oxygenase enzymes in the basal ganglia and their roles in Parkinson's disease. Adv Neurol 1999;80:271-86.
-
(1999)
Adv Neurol
, vol.80
, pp. 271-286
-
-
Riedl, A.G.1
Watts, P.M.2
Brown, C.T.3
Jenner, P.4
-
125
-
-
0029122803
-
The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimers disease
-
Chen X, Xia Y, Alford M, DeTeresa R, Hansen L, Klauber MR, et al. The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimers disease. Ann Neurol 1995;38:653-8.
-
(1995)
Ann Neurol
, vol.38
, pp. 653-658
-
-
Chen, X.1
Xia, Y.2
Alford, M.3
DeTeresa, R.4
Hansen, L.5
Klauber, M.R.6
-
126
-
-
0028921457
-
The CYP2D6B mutant allele is overrepresented in the Lewy body vaiant of Alzheimer's disease
-
Saitoh T, Xia Y, Chen X, Masliah E, Galasko D, Shults C, et al. The CYP2D6B mutant allele is overrepresented in the Lewy body vaiant of Alzheimer's disease. Ann Neurol 1995;37:110-2.
-
(1995)
Ann Neurol
, vol.37
, pp. 110-112
-
-
Saitoh, T.1
Xia, Y.2
Chen, X.3
Masliah, E.4
Galasko, D.5
Shults, C.6
-
127
-
-
0031779185
-
Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease
-
Tanaka S, Chen X, Xia Y, Kang DE, Matoh N, Sundsmo M, et al. Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease. Neurology 1998;50:1556-62.
-
(1998)
Neurology
, vol.50
, pp. 1556-1562
-
-
Tanaka, S.1
Chen, X.2
Xia, Y.3
Kang, D.E.4
Matoh, N.5
Sundsmo, M.6
-
128
-
-
0035137665
-
Inhibition of cytochrome P450 2C9 activity in vitro by 5-hydroxytryptamine and adrenaline
-
Gervasini G, Martinez C, Agundez AAG, Garcia-Gamito FJ, Benitez J. Inhibition of cytochrome P450 2C9 activity in vitro by 5-hydroxytryptamine and adrenaline. Pharmacogenetics 2001;11:29-37.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 29-37
-
-
Gervasini, G.1
Martinez, C.2
Agundez, A.A.G.3
Garcia-Gamito, F.J.4
Benitez, J.5
-
129
-
-
0027940480
-
Regio- and stereoselective epoxidation of arachidonic acid aby human cytochromes P450 2C8 and 2C9
-
Daikh BE, Lasker JM, Raucy JL, Koop DR. Regio- and stereoselective epoxidation of arachidonic acid aby human cytochromes P450 2C8 and 2C9. J Pharmacol Exp Ther 1994;271:1427-33.
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1427-1433
-
-
Daikh, B.E.1
Lasker, J.M.2
Raucy, J.L.3
Koop, D.R.4
-
130
-
-
0035816583
-
Cytochrome P450 CYP2J9, a new mouse arachidonic acid ω-1 hydroxylase predominantly expressed in brain
-
Qu W, Bradbury JA, Tsao C, Maronpot R, Harry GJ, Parker CE, et al. Cytochrome P450 CYP2J9, a new mouse arachidonic acid ω-1 hydroxylase predominantly expressed in brain. J Biol Chem 2001;276:25467-79.
-
(2001)
J Biol Chem
, vol.276
, pp. 25467-25479
-
-
Qu, W.1
Bradbury, J.A.2
Tsao, C.3
Maronpot, R.4
Harry, G.J.5
Parker, C.E.6
-
131
-
-
0029039791
-
Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes
-
Rifkind AB, Lee C, Chang TK, Waxman DJ. Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes. Arch Biochem Biophys 1995;320:380-9.
-
(1995)
Arch Biochem Biophys
, vol.320
, pp. 380-389
-
-
Rifkind, A.B.1
Lee, C.2
Chang, T.K.3
Waxman, D.J.4
-
132
-
-
0031049745
-
The cytochrome P450 4 (CYP4) family
-
Simpson AE. The cytochrome P450 4 (CYP4) family. Gen Pharmac 1997;28:351-9.
-
(1997)
Gen Pharmac
, vol.28
, pp. 351-359
-
-
Simpson, A.E.1
-
133
-
-
0029122098
-
Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform
-
Zeldin DC, DuBois RN, Falck JR, Capdevila JH. Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochern Biophys 1995;322:76-86.
-
(1995)
Arch Biochern Biophys
, vol.322
, pp. 76-86
-
-
Zeldin, D.C.1
DuBois, R.N.2
Falck, J.R.3
Capdevila, J.H.4
-
134
-
-
0029825785
-
CYP2J subfamily P450s in the lung: Expression, localization, and potential functional significance
-
Zeldin DC, Foley J, Ma J, Boyle JE, Pascual JM, Moomaw CR, et al. CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. Mol Pharmacol 1996;50:1111-7.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1111-1117
-
-
Zeldin, D.C.1
Foley, J.2
Ma, J.3
Boyle, J.E.4
Pascual, J.M.5
Moomaw, C.R.6
-
135
-
-
0028930148
-
The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway; characterization and significance
-
Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, et al. The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway; characterization and significance. J Clin Invest 1995;95:2150-60.
-
(1995)
J Clin Invest
, vol.95
, pp. 2150-2160
-
-
Zeldin, D.C.1
Plitman, J.D.2
Kobayashi, J.3
Miller, R.F.4
Snapper, J.R.5
Falck, J.R.6
-
136
-
-
0002595605
-
Cytochrome P450 and the metabolism of arachidonic acid and oxygenated eicosanoids
-
Ortiz de Montellano PR, editor. New York: Plenum Press
-
Capdevila JH, Zeldin D, Makita K, Karara A, Falck JR. Cytochrome P450 and the metabolism of arachidonic acid and oxygenated eicosanoids. In: Ortiz de Montellano PR, editor. Cytochrome P450: structure, mechanism, biochemistry. New York: Plenum Press; 1995. p. 443-71.
-
(1995)
Cytochrome P450: Structure, Mechanism, Biochemistry
, pp. 443-471
-
-
Capdevila, J.H.1
Zeldin, D.2
Makita, K.3
Karara, A.4
Falck, J.R.5
-
137
-
-
33750807720
-
Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow
-
Alkayed NJ, Birks EK, Hudetz AG, Roman RJ, Henderson L, Harder DR. Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol 1996;271:1541-6.
-
(1996)
Am J Physiol
, vol.271
, pp. 1541-1546
-
-
Alkayed, N.J.1
Birks, E.K.2
Hudetz, A.G.3
Roman, R.J.4
Henderson, L.5
Harder, D.R.6
-
138
-
-
0029930387
-
Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes
-
Alkayed NJ, Narayanan J, Gebremedhin D, Medhora M, Roman RJ, Harder DR. Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke 1996;27:971-9.
-
(1996)
Stroke
, vol.27
, pp. 971-979
-
-
Alkayed, N.J.1
Narayanan, J.2
Gebremedhin, D.3
Medhora, M.4
Roman, R.J.5
Harder, D.R.6
-
139
-
-
0026584785
-
Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid
-
Amruthesh SC, Falck JR, Ellis EF. Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid. J Neurochem 1992;58:503-10.
-
(1992)
J Neurochem
, vol.58
, pp. 503-510
-
-
Amruthesh, S.C.1
Falck, J.R.2
Ellis, E.F.3
-
140
-
-
0025133442
-
Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid
-
Ellis EF, Police RJ, Yancey L, McKinney JS, Amruthesh SC. Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid. Am J Physiol 1990;259:H1171-7.
-
(1990)
Am J Physiol
, vol.259
-
-
Ellis, E.F.1
Police, R.J.2
Yancey, L.3
McKinney, J.S.4
Amruthesh, S.C.5
-
141
-
-
0034617142
-
Production of 20-HETE and its role in autoregulation of cerebral blood flow
-
Gebremedhin D, Lange AR, Lowry TF, RezaTaheri M, Birks EK, Hundetz AG, et al. Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res 2000;87:60-5.
-
(2000)
Circ Res
, vol.87
, pp. 60-65
-
-
Gebremedhin, D.1
Lange, A.R.2
Lowry, T.F.3
RezaTaheri, M.4
Birks, E.K.5
Hundetz, A.G.6
-
142
-
-
0026758963
-
Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle
-
Gebremedhin D, Ma YH, Falck JR, Roman RJ, VanRollins M, Harder DR. Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol 1992;263:519-25.
-
(1992)
Am J Physiol
, vol.263
, pp. 519-525
-
-
Gebremedhin, D.1
Ma, Y.H.2
Falck, J.R.3
Roman, R.J.4
VanRollins, M.5
Harder, D.R.6
-
143
-
-
0032425022
-
A common pathway for regulation of nutritive blood flow to the brain: Arterial muscle membrane potential and cytochrome P450 metabolites
-
Harder DR, Roman RJ, Gebremedhin D, Birks EK, Lange AR. A common pathway for regulation of nutritive blood flow to the brain: arterial muscle membrane potential and cytochrome P450 metabolites. Acta Physiol Scand 1998;164:527-32.
-
(1998)
Acta Physiol Scand
, vol.164
, pp. 527-532
-
-
Harder, D.R.1
Roman, R.J.2
Gebremedhin, D.3
Birks, E.K.4
Lange, A.R.5
-
144
-
-
0020510129
-
Novel hypothalamic arachidonate products stimulate somatostatin release from the median eminence
-
Capdevila J, Chacos N, Falck JR, Manna S, Negro-Vilar A, Ojeda SR. Novel hypothalamic arachidonate products stimulate somatostatin release from the median eminence. Endocrinology 1983;113:421-3.
-
(1983)
Endocrinology
, vol.113
, pp. 421-423
-
-
Capdevila, J.1
Chacos, N.2
Falck, J.R.3
Manna, S.4
Negro-Vilar, A.5
Ojeda, S.R.6
-
145
-
-
0023201055
-
Epoxy derivatives of arachidonic acid are potent stimulators of prolactin secretion
-
Cashman JR, Hanks D, Weiner RI. Epoxy derivatives of arachidonic acid are potent stimulators of prolactin secretion. Neuroendocrinology 1987;46:246-51.
-
(1987)
Neuroendocrinology
, vol.46
, pp. 246-251
-
-
Cashman, J.R.1
Hanks, D.2
Weiner, R.I.3
-
146
-
-
0025264864
-
Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin
-
Junier MP, Dray F, Blair I, Capdevila J, Dishman E, Falck JR, et al. Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin. Endocrinology 1990;126:1534-40.
-
(1990)
Endocrinology
, vol.126
, pp. 1534-1540
-
-
Junier, M.P.1
Dray, F.2
Blair, I.3
Capdevila, J.4
Dishman, E.5
Falck, J.R.6
-
147
-
-
0025603721
-
Contribution of arachidonate metabolites to basal and thyrotropin releasing-hormone-stimulated release of prolactin from purified lactotrophs in primary culture
-
Junier MP, Israel JM, Dray F, Vincent JD. Contribution of arachidonate metabolites to basal and thyrotropin releasing-hormone-stimulated release of prolactin from purified lactotrophs in primary culture. Life Sci 1990;47:1829-36.
-
(1990)
Life Sci
, vol.47
, pp. 1829-1836
-
-
Junier, M.P.1
Israel, J.M.2
Dray, F.3
Vincent, J.D.4
-
148
-
-
0020525067
-
Action of luteinizing hormone-releasing hormone: Involvement of novel arachidonic acid metabolites
-
Snyder GD, Capdevila J, Chacos N, Manna S, Falck JR. Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites. Proc Natl Acad Sci U S A 1983;80:3504-7.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 3504-3507
-
-
Snyder, G.D.1
Capdevila, J.2
Chacos, N.3
Manna, S.4
Falck, J.R.5
-
149
-
-
0032521122
-
Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current
-
Gebremedhin D, Lange AR, Narayanan J, Aebly MR, Jacobs ER, Harder DR. Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current. J Physiol 1998;507:771-81.
-
(1998)
J Physiol
, vol.507
, pp. 771-781
-
-
Gebremedhin, D.1
Lange, A.R.2
Narayanan, J.3
Aebly, M.R.4
Jacobs, E.R.5
Harder, D.R.6
-
150
-
-
0035206892
-
Neurosteroid metabolism in the human brain
-
Stoffel-Wagner B. Neurosteroid metabolism in the human brain. Eur J Endocrinol 2001;145:669-79.
-
(2001)
Eur J Endocrinol
, vol.145
, pp. 669-679
-
-
Stoffel-Wagner, B.1
-
151
-
-
0032824251
-
Neurosteroid biosynthesis in vertebrate brains
-
Tsutsui K, Ukena K, Takase M, Kohchi C, Lea RW. Neurosteroid biosynthesis in vertebrate brains. Comp Biochem Physiol C 1999;124:121-9.
-
(1999)
Comp Biochem Physiol C
, vol.124
, pp. 121-129
-
-
Tsutsui, K.1
Ukena, K.2
Takase, M.3
Kohchi, C.4
Lea, R.W.5
-
152
-
-
0029118238
-
Cytochrome P450 in the brain: Neuroendocrine functions
-
Warner M, Gustafsson J-A. Cytochrome P450 in the brain: neuroendocrine functions. Front Neuroendocrinol 1995;16:224-36.
-
(1995)
Front Neuroendocrinol
, vol.16
, pp. 224-236
-
-
Warner, M.1
Gustafsson, J.-A.2
-
153
-
-
0034913104
-
Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis
-
Kimoto T, Tsurugizawa T, Ohta Y, Makino J, Tamura H, Hojo Y, et al. Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology 2001;142:3578-89.
-
(2001)
Endocrinology
, vol.142
, pp. 3578-3589
-
-
Kimoto, T.1
Tsurugizawa, T.2
Ohta, Y.3
Makino, J.4
Tamura, H.5
Hojo, Y.6
-
154
-
-
0032910967
-
Dehydroepiandrosterone: Biosynthesis and metabolism in the brain
-
Zwain IH, Yen SS. Dehydroepiandrosterone: biosynthesis and metabolism in the brain. Endocrinology 1999;140:880-7.
-
(1999)
Endocrinology
, vol.140
, pp. 880-887
-
-
Zwain, I.H.1
Yen, S.S.2
-
155
-
-
0033305132
-
Neurosteroidogenesis in astrocytes, oligodendrocytes and neurons of cerebral cortex of rat brain
-
Zwain IH, Yen SS. Neurosteroidogenesis in astrocytes, oligodendrocytes and neurons of cerebral cortex of rat brain. Endocrinolgy 1999;140:3843-52.
-
(1999)
Endocrinolgy
, vol.140
, pp. 3843-3852
-
-
Zwain, I.H.1
Yen, S.S.2
-
156
-
-
0034800442
-
Role of human cytochrome P450 1A1, 1A2, 1B1 and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol
-
Badawi AF, Cavalieri EL, Rogan EG. Role of human cytochrome P450 1A1, 1A2, 1B1 and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol. Metabolism 2001;50:1001-3.
-
(2001)
Metabolism
, vol.50
, pp. 1001-1003
-
-
Badawi, A.F.1
Cavalieri, E.L.2
Rogan, E.G.3
-
157
-
-
0031283159
-
Dehydroepiandrosterone 7alpha- and 7beta-hydroxylation in mouse brain micrsomes. Effects of cytochrome P450 inhibitors and structure-specific inhibition by steroid hormones
-
Doostzadeh J, Cotillon AC, Morfin R. Dehydroepiandrosterone 7alpha- and 7beta-hydroxylation in mouse brain micrsomes. Effects of cytochrome P450 inhibitors and structure-specific inhibition by steroid hormones. J Neuroendocrinol 1997;9:923-8.
-
(1997)
J Neuroendocrinol
, vol.9
, pp. 923-928
-
-
Doostzadeh, J.1
Cotillon, A.C.2
Morfin, R.3
-
158
-
-
0030720779
-
Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metablites of pregnenolone in mouse brain microsomes
-
Doostzadeh J, Morfin R. Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metablites of pregnenolone in mouse brain microsomes. J Endocrinol 1997;155:343-50.
-
(1997)
J Endocrinol
, vol.155
, pp. 343-350
-
-
Doostzadeh, J.1
Morfin, R.2
-
159
-
-
0030436261
-
Pregnenolone-7 beta-hydroxylating activities of yeast expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes
-
Doostzadeh J, Urban P, Pompon D, Morfin R. Pregnenolone-7 beta-hydroxylating activities of yeast expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes. Eur J Biochem 1996;242:641-7.
-
(1996)
Eur J Biochem
, vol.242
, pp. 641-647
-
-
Doostzadeh, J.1
Urban, P.2
Pompon, D.3
Morfin, R.4
-
160
-
-
0034869539
-
Progesterone oxidation by cytochrome P450 2D isoforms in the brain
-
Hiroi T, Kishimoto W, Chow T, Imaoka S, Igarashi T, Funae Y. Progesterone oxidation by cytochrome P450 2D isoforms in the brain. Endocrinology 2001;142:3901-8.
-
(2001)
Endocrinology
, vol.142
, pp. 3901-3908
-
-
Hiroi, T.1
Kishimoto, W.2
Chow, T.3
Imaoka, S.4
Igarashi, T.5
Funae, Y.6
-
161
-
-
0033656861
-
Cytochrome P450 3A9 catalyzes the metabolism of progesterone and other steroid hormones
-
Wang H, Napoli KL, Strobel HW. Cytochrome P450 3A9 catalyzes the metabolism of progesterone and other steroid hormones. Mol Cell Biochem 2000;213:127-35.
-
(2000)
Mol Cell Biochem
, vol.213
, pp. 127-135
-
-
Wang, H.1
Napoli, K.L.2
Strobel, H.W.3
-
163
-
-
0035968215
-
Neurosteroid hydroxylase CYP7B vivd reporter activity in dentate gyrus of gene-targeted mice and abolition of a widspread pathway of steroid and oxysterol hydroxylation
-
Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, et al. Neurosteroid hydroxylase CYP7B vivd reporter activity in dentate gyrus of gene-targeted mice and abolition of a widspread pathway of steroid and oxysterol hydroxylation. J Biol Chem 2001;276:23937-44.
-
(2001)
J Biol Chem
, vol.276
, pp. 23937-23944
-
-
Rose, K.1
Allan, A.2
Gauldie, S.3
Stapleton, G.4
Dobbie, L.5
Dott, K.6
-
164
-
-
12644253822
-
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7 alpha-hydroxy dehydroepiandrosterone and 7 alpha-hydroxy pregnenolone
-
Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, et al. Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7 alpha-hydroxy dehydroepiandrosterone and 7 alpha-hydroxy pregnenolone. Proc Natl Acad Sci U S A 1997;94:4925-30.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4925-4930
-
-
Rose, K.A.1
Stapleton, G.2
Dott, K.3
Kieny, M.P.4
Best, R.5
Schwarz, M.6
-
165
-
-
0029812219
-
Anatomical distribution of NADPH-cytochrome P450 reductase and cytochrome P4502D forms in rat brain: Effects of xenobiotics and sex steroids
-
Bergh AF, Strobel HW. Anatomical distribution of NADPH-cytochrome P450 reductase and cytochrome P4502D forms in rat brain: effects of xenobiotics and sex steroids. Mol Cell Biochem 1996;162:31-41.
-
(1996)
Mol Cell Biochem
, vol.162
, pp. 31-41
-
-
Bergh, A.F.1
Strobel, H.W.2
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