메뉴 건너뛰기




Volumn 366, Issue 2, 1996, Pages 244-258

Regional distribution of cytochrome P450 2D1 in the rat central nervous system

Author keywords

catecholamine metabolism; neurotoxin; Parkinson's disease; polymorphism; xenobiotics

Indexed keywords

CYTOCHROME P450; NEUROTOXIN;

EID: 0030053243     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960304)366:2<244::AID-CNE5>3.0.CO;2-5     Document Type: Article
Times cited : (50)

References (48)
  • 2
    • 0025598114 scopus 로고
    • Rat brain cytochromes P-450: Catalytic, immunochemical properties and inducibility of multiple forms
    • Anandatheerthavarada, H.K., S.K. Shankar, and V. Ravindranath (1990) Rat brain cytochromes P-450: catalytic, immunochemical properties and inducibility of multiple forms. Brain Res. 536:339-343.
    • (1990) Brain Res. , vol.536 , pp. 339-343
    • Anandatheerthavarada, H.K.1    Shankar, S.K.2    Ravindranath, V.3
  • 3
    • 0023187594 scopus 로고
    • 3H] GBR-12935 binding in vitro to rat striatal membranes: Labelling of the dopamine uptake complex
    • 3H] GBR-12935 binding in vitro to rat striatal membranes: labelling of the dopamine uptake complex. J Neurochem. 48.1887-1896.
    • (1987) J Neurochem. , vol.48 , pp. 1887-1896
    • Anderson, P.H.1
  • 4
    • 0026589459 scopus 로고
    • Mutant debrisoquine hydroxylation genes in Parkinson's disease
    • Armstrong, M., A.K. Daly, S. Cholerton, D.N. Bateman, and J.R. Idle (1992) Mutant debrisoquine hydroxylation genes in Parkinson's disease. Lancet 339:1017-1018.
    • (1992) Lancet , vol.339 , pp. 1017-1018
    • Armstrong, M.1    Daly, A.K.2    Cholerton, S.3    Bateman, D.N.4    Idle, J.R.5
  • 5
    • 0022408175 scopus 로고
    • Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
    • Barbeau, A., M. Roy, S Paris, T. Cloutier, L. Plasse, and J. Poirier (1985) Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 2:1213-1216
    • (1985) Lancet , vol.2 , pp. 1213-1216
    • Barbeau, A.1    Roy, M.2    Paris, S.3    Cloutier, T.4    Plasse, L.5    Poirier, J.6
  • 6
    • 0027244082 scopus 로고
    • Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities
    • Bhamre, S., H.K. Anandatheerathavarada, S.K. Shankar, M.R. Boyd, and V Ravindranath (1993) Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities. Arch. Biochem Biophys 301 251-255.
    • (1993) Arch. Biochem Biophys , vol.301 , pp. 251-255
    • Bhamre, S.1    Anandatheerathavarada, H.K.2    Shankar, S.K.3    Boyd, M.R.4    Ravindranath, V.5
  • 7
    • 0026569583 scopus 로고
    • Membrane topology of the mammalian P450 cytochromes
    • Black, S.D. (1992) Membrane topology of the mammalian P450 cytochromes. FASEB J. 6:680-681.
    • (1992) FASEB J. , vol.6 , pp. 680-681
    • Black, S.D.1
  • 8
    • 0026496950 scopus 로고
    • The role of individual human cytochromes P450 in drug metabolism and clinical response
    • Cholerton, S., A K. Daly, and J.R. Idle (1992) The role of individual human cytochromes P450 in drug metabolism and clinical response. Trends Pharmacol. Sci. 13:434-439.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 434-439
    • Cholerton, S.1    Daly, A.K.2    Idle, J.R.3
  • 9
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczyski, P , and N. Sacchi (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczyski, P.1    Sacchi, N.2
  • 11
    • 0023568113 scopus 로고
    • MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufl, P450db1) catalyzing debrisoquine 4-hydroxylation
    • Fonne-Pfister, R., M.J. Bargetzi, and U.A. Meyer (1987) MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufl, P450db1) catalyzing debrisoquine 4-hydroxylation. Biochem. Biophys Res. Commun. 148:1144-1150.
    • (1987) Biochem. Biophys Res. Commun. , vol.148 , pp. 1144-1150
    • Fonne-Pfister, R.1    Bargetzi, M.J.2    Meyer, U.A.3
  • 13
    • 0027535205 scopus 로고
    • Molecular characterization of the dopamine transporter
    • Giros, B., and M.G. Caron (1993) Molecular characterization of the dopamine transporter. Trends Pharmacol. Sci. 14:43-49.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 43-49
    • Giros, B.1    Caron, M.G.2
  • 14
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450s
    • Gonzalez, F. J. (1989) The molecular biology of cytochrome P450s. Pharmacol. Rev. 40:243-288
    • (1989) Pharmacol. Rev. , vol.40 , pp. 243-288
    • Gonzalez, F.J.1
  • 15
    • 0023154962 scopus 로고
    • Debrisoquine 4-hydroxylase: Characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism
    • Gonzalez, F.J., T. Matsunaga, K. Nagata, U.A. Meyer, D.W. Nebert, J. Pastewka, C.A. Kozak, J. Gillette, H.V. Gelboin, and J.P. Hardwick (1987) Debrisoquine 4-hydroxylase: Characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism. DNA 6:149-161.
    • (1987) DNA , vol.6 , pp. 149-161
    • Gonzalez, F.J.1    Matsunaga, T.2    Nagata, K.3    Meyer, U.A.4    Nebert, D.W.5    Pastewka, J.6    Kozak, C.A.7    Gillette, J.8    Gelboin, H.V.9    Hardwick, J.P.10
  • 18
    • 0026507870 scopus 로고
    • Human cytochrome P-450 enzymes
    • Guengerich, F. P. (1992) Human cytochrome P-450 enzymes. Life Sci. 50.1471-1478.
    • (1992) Life Sci. , vol.50 , pp. 1471-1478
    • Guengerich, F.P.1
  • 19
    • 0020084018 scopus 로고
    • Cytochrome P-450 dependent monooxygenase activity in rat nasal epithelial membranes
    • Hadley, W.M., and A R. Dahl (1982) Cytochrome P-450 dependent monooxygenase activity in rat nasal epithelial membranes. Toxicol. Lett. 10:417-422.
    • (1982) Toxicol. Lett. , vol.10 , pp. 417-422
    • Hadley, W.M.1    Dahl, A.R.2
  • 20
    • 0021215509 scopus 로고
    • Presence of NADPH-cytochrome P450 reductase in central catecholammergic neurones
    • Haglund, L., C. Kohler, T. Haaparanta, M. Goldstein, and J.-Å. Gustafsson (1984) Presence of NADPH-cytochrome P450 reductase in central catecholammergic neurones. Nature 307.259-262.
    • (1984) Nature , vol.307 , pp. 259-262
    • Haglund, L.1    Kohler, C.2    Haaparanta, T.3    Goldstein, M.4    Gustafsson, J.-Å.5
  • 21
    • 0025356936 scopus 로고
    • Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system
    • Hansson, T., N. Tindberg, M. Ingelman-Sundberg, and C. Köhler (1990) Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system. Neuroscience 34:451-463.
    • (1990) Neuroscience , vol.34 , pp. 451-463
    • Hansson, T.1    Tindberg, N.2    Ingelman-Sundberg, M.3    Köhler, C.4
  • 23
    • 0027419153 scopus 로고
    • Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction
    • Hodgson, A.V., T.B. White, J.W. White, and H.W. Strobel (1993) Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction. Mol. Cell. Biochem. 120:171-179.
    • (1993) Mol. Cell. Biochem. , vol.120 , pp. 171-179
    • Hodgson, A.V.1    White, T.B.2    White, J.W.3    Strobel, H.W.4
  • 24
    • 0019423594 scopus 로고
    • The use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques. A comparison between ABC and unlabeled antibody (PAP) procedure
    • Hsu, S.M., L. Raine, and H Fanger (1982) The use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques. A comparison between ABC and unlabeled antibody (PAP) procedure. J. Histochem Cytochem 59:577-580.
    • (1982) J. Histochem Cytochem , vol.59 , pp. 577-580
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 25
    • 0025369152 scopus 로고
    • Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: The olfactory bulb and the mitochondrial fraction have high levels of activity
    • Iscan, M., K Reuhl, B. Weiss, and M.D. Maines (1990) Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: The olfactory bulb and the mitochondrial fraction have high levels of activity. Biochem. Biophys. Res. Commun. 169:858-863
    • (1990) Biochem. Biophys. Res. Commun. , vol.169 , pp. 858-863
    • Iscan, M.1    Reuhl, K.2    Weiss, B.3    Maines, M.D.4
  • 26
    • 0028211714 scopus 로고
    • Up-regulation of nitric oxide synthase (NOS) gene expression together with NOS activity in the rat hypothalamo-hypophysial system after chronic salt loading: Evidence of a neuromodulatory role of nitric oxide in arginine vasopressin and oxytocin secretion
    • Kadowaki, K., J. Kishimoto, G. Leng, and P.C. Emson (1994) Up-regulation of nitric oxide synthase (NOS) gene expression together with NOS activity in the rat hypothalamo-hypophysial system after chronic salt loading: evidence of a neuromodulatory role of nitric oxide in arginine vasopressin and oxytocin secretion. Endocrinology 134:1011-1017.
    • (1994) Endocrinology , vol.134 , pp. 1011-1017
    • Kadowaki, K.1    Kishimoto, J.2    Leng, G.3    Emson, P.C.4
  • 29
    • 0027515851 scopus 로고
    • A novel P450 expressed at the high level in rat brain
    • Komori, M. (1993) A novel P450 expressed at the high level in rat brain. Biochem. Biophys. Res. Commun. 196:721-728.
    • (1993) Biochem. Biophys. Res. Commun. , vol.196 , pp. 721-728
    • Komori, M.1
  • 30
    • 0027502074 scopus 로고
    • Variations in drug metabolism due to genetic polymorphism. A review of the debrisoquine/sparteme type
    • Lledó, P. (1993) Variations in drug metabolism due to genetic polymorphism. A review of the debrisoquine/sparteme type Drug Invest. 5:19-34.
    • (1993) Drug Invest. , vol.5 , pp. 19-34
    • Lledó, P.1
  • 31
    • 0023821395 scopus 로고
    • 3H]GBR-12935 binding to dopamine uptake sites in the human brain
    • 3H]GBR-12935 binding to dopamine uptake sites in the human brain. Brain Res. 457:122-129.
    • (1988) Brain Res. , vol.457 , pp. 122-129
    • Mareusson, J.1    Eriksson, K.2
  • 36
    • 0028246977 scopus 로고
    • Localization of NADPH cytochrome P450 oxidoreductase in rat brain by immunohistochemistry and in situ hybridization and a comparison with the distribution of neuronal NADPH-diaphorase staining
    • Norris, P.J., J.P. Hardwick, and P.C. Emson (1994) Localization of NADPH cytochrome P450 oxidoreductase in rat brain by immunohistochemistry and in situ hybridization and a comparison with the distribution of neuronal NADPH-diaphorase staining. Neuroscience 61:331-350.
    • (1994) Neuroscience , vol.61 , pp. 331-350
    • Norris, P.J.1    Hardwick, J.P.2    Emson, P.C.3
  • 37
    • 0025136874 scopus 로고
    • Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal-model of a poor debrisoquine metabolizer
    • Ohta, S., O. Tachikawa, Y. Makino, Y Tasaki, and M. Hirobe (1990) Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal-model of a poor debrisoquine metabolizer. Life Sci. 46:599-605.
    • (1990) Life Sci. , vol.46 , pp. 599-605
    • Ohta, S.1    Tachikawa, O.2    Makino, Y.3    Tasaki, Y.4    Hirobe, M.5
  • 38
    • 0025819615 scopus 로고
    • Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducers: In vitro studies with brain slices
    • Pai, K.S., and V. Ravindranath (1991) Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducers: in vitro studies with brain slices. Brain Res. 555:239-244
    • (1991) Brain Res. , vol.555 , pp. 239-244
    • Pai, K.S.1    Ravindranath, V.2
  • 39
    • 0022375615 scopus 로고
    • The protective effect of 1-tert, butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration causedby 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Przuntek, H., H. Russ, K. Henning, and U. Pindur (1985) The protective effect of 1-tert, butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration causedby 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Life Sci. 37:1195-2000.
    • (1985) Life Sci. , vol.37 , pp. 1195-2000
    • Przuntek, H.1    Russ, H.2    Henning, K.3    Pindur, U.4
  • 40
    • 0024315016 scopus 로고
    • Xenobiotic metabolism in human brain - Presence of cytochrome P-450 and associated mono-oxygenases
    • Ravindranath, V., H K. Anandatheerthavarada, and S.K. Shankar (1989) Xenobiotic metabolism in human brain - presence of cytochrome P-450 and associated mono-oxygenases. Brain Res. 496:331-335.
    • (1989) Brain Res. , vol.496 , pp. 331-335
    • Ravindranath, V.1    Anandatheerthavarada, H.K.2    Shankar, S.K.3
  • 42
    • 0024570529 scopus 로고
    • Studies on the interactions of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) with the cytochrome P-450 enzyme system - Clues to a possible aetiological factor in Parkinson's disease
    • Shahi, G.S , S.M. Moochhala, E.J.D. Lee, and N.P. Das (1989) Studies on the interactions of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) with the cytochrome P-450 enzyme system - clues to a possible aetiological factor in Parkinson's disease. Ann. Acad. Med. 18:93-97.
    • (1989) Ann. Acad. Med. , vol.18 , pp. 93-97
    • Shahi, G.S.1    Moochhala, S.2    Lee, E.J.D.3    Das, N.P.4
  • 43
    • 0345638787 scopus 로고
    • Two mutant alleles of the human cytochrome P-450db1 gene (P4502D1) associated with genetically deficient metabolism of debrisoquine and other drugs
    • Skoda, R.C., F.J. Gonzalez, A. Demierre, and U.A. Meyer (1988) Two mutant alleles of the human cytochrome P-450db1 gene (P4502D1) associated with genetically deficient metabolism of debrisoquine and other drugs. Proc Natl. Acad. Sci U.S A 85:5240-5243.
    • (1988) Proc Natl. Acad. Sci U.S A , vol.85 , pp. 5240-5243
    • Skoda, R.C.1    Gonzalez, F.J.2    Demierre, A.3    Meyer, U.A.4
  • 45
    • 0026512229 scopus 로고
    • Cytochrome P450 isozymes catayzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroquinoline in rat liver microsomes
    • Suzuki, T., S. Fujita, S. Narimatsu, Y. Masubuchi, M. Tachibana, S. Ohta, and M Hirobe (1992) Cytochrome P450 isozymes catayzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroquinoline in rat liver microsomes. FASEB J. 6:771-776.
    • (1992) FASEB J. , vol.6 , pp. 771-776
    • Suzuki, T.1    Fujita, S.2    Narimatsu, S.3    Masubuchi, Y.4    Tachibana, M.5    Ohta, S.6    Hirobe, M.7
  • 47
    • 0025779409 scopus 로고
    • Neuronal cytochrome CYP2D1 (debrisoquine/sparteinetype): Potent inhibition of activity by (-)-cocaine and nucleotide sequence identity with human hepatic P450 gene CYP2D6
    • Tyndale, R.F , R Sunahara, T. Inaba, W. Kalow, F.J. Gonzalez, and H B. Niznik (1991) Neuronal cytochrome CYP2D1 (debrisoquine/sparteinetype): Potent inhibition of activity by (-)-cocaine and nucleotide sequence identity with human hepatic P450 gene CYP2D6. Mol Pharmacol. 40:63-68.
    • (1991) Mol Pharmacol. , vol.40 , pp. 63-68
    • Tyndale, R.F.1    Sunahara, R.2    Inaba, T.3    Kalow, W.4    Gonzalez, F.J.5    Niznik, H.B.6
  • 48
    • 0023948926 scopus 로고
    • Regional distribution of cytochrome P-450 in the rat brain: Spectral quantification and contribution of P-450b,e and P-450c,d
    • Warner, M., C. Köhler, T. Hansson, and J.-Å. Gustafsson (1988) Regional distribution of cytochrome P-450 in the rat brain: spectral quantification and contribution of P-450b,e and P-450c,d. J. Neurochem. 50.1057-1065.
    • (1988) J. Neurochem. , vol.50 , pp. 1057-1065
    • Warner, M.1    Köhler, C.2    Hansson, T.3    Gustafsson, J.-Å.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.