Cytochrome P450 1B1 mRNA in the human central nervous system

Journal of Clinical Pathology - Molecular Pathology

Volumn 51, Issue 3, 1998, Pages 138-142

  Rieder, C R M ^a   Ramsden, D B ^a   Williams, A C ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

CYP1B1; Cytochrome P450; Neurodegenerative diseases; Parkinson's disease

Indexed keywords

CYTOCHROME P450; MESSENGER RNA;

ARTICLE; BRAIN METABOLISM; DEGENERATIVE DISEASE; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NERVE CELL CULTURE; NEUROLOGIC DISEASE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE;

EID: 0031926298     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.51.3.138     Document Type: Article

References (46)

1. Denison M, Whitlock J. Xenobiotic-inducible transcription of cytochrome P450 genes. J Biol Chem 1995;270:18175-8.
2. Gonzalez F. Human cytochromes P450: problems and prospects. Trends Pharmacol Sci 1992;13:346-52.
3. Neben D, Gonzalez F. P450 genes: structure, evolution, and regulation. Annu Rev Biochem 1987;56:945-93.
4. Nebert D, Nelson DR, Coon MJ, et al. The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol 1991;10:1-14.
5. Hirvonen A. Genetic factors in individual responses to environmental exposures. J Occupat Environ Med 1995;37:37-43.
6. Guengerich FP. Human cytochrome P-450 enzymes. Life Sci 1992;50:1471-8.
7. Mesnil M, Testa B, Jenner P. Xenobiotic metabolism by brain monooxygenases and other cerebral enzymes. Adv Drug Res 1984;13:95-207.
8. Ravindranath V, Bhamre S, Bhagwat SV, et al. Xenobiotic metabolism in brain. Toxicol Lett 1995;82:633-8.
9. Bhagwat S, Boyd M, Ravindranath V. Brain mitochondrial cytochromes P450: Xenobiotic metabolism, presence of multiple forms and their selective inducibility. Arch Biochem Biophys 1995;320:73-83.
10. Mills JC, Nelson D, Erecinska M, et al. Metabolic and energetic changes during apoptosis in neural cells. J Neurochem 1995;65:1721-30.
11. Anandatheerthavarada HK, Shankar SK, Ravindranath V. Rat-brain cytochromes P-450: catalytic, immunochemical properties and inducibility of multiple forms. Brain Res 1990;536:339-43.
12. Montoliu C, Sanchotello M, Azorin I, et al. Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes. J Neurochem 1995;65:2561-70.
13. Smith CAD, Gough AC, Leigh PN, et al. Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's-disease. Lancet 1992;339:1375-7.
14. Armstrong M, Daly A, Cholerton S, et al. Mutant debrisoquine hydroxylation genes in Parkinson's disease. Lancet 1992;339:1017-18.
15. 5 Agundez JAG, Jimenez-Jimenez FJ, Luengo A, et al. Association between the oxidative polymorphism and early-onset of Parkinson's-disease. Clin Pharmacol Ther 1995;57: 291-8.
16. Takakubo F, Yamamoto M, Ogawa N, et al. Genetic association between cytochrome P450IA1 gene and susceptibility to Parkinson's-disease. J Neurol Transm 1996;103:843-9.
17. Coleman T, Ellis SW, Martin IJ, et al. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4: implications for susceptibility to Parkinson's-disease. J Pharmacol Exper Ther 1996;277:685-690.
18. Gilham DE, Cairns W, Paine MJI, et al. Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization. Xenobiotica 1997;27:111-25.
19. Narimatsu S, Tachibana M, Masubuchi Y, et al. Cytochrome P4502D and P4502C enzymes catalyze the oxidative N-demethylation of the Parkinsonism-inducing substance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rat-liver microsomes. Chem Res Toxicol 1996;9:93-8.
20. Pai KS, Ravindranath V. Protection and potentiation Of MPTP-induced toxicity by cytochrome-P-450 inhibitors and inducer: in vitro studies with brain-slices. Brain Res 1991;555:239-44.
21. Sriram K, Pai KS, Ravindranath V. Protection and potentiation of 1-methyl-4-phenylpyridinium induced toxicity by cytochrome-P450 inhibitors and inducer may be due to the altered uptake of the toxin. J Neurochem 1995;64:1203-8.
22. Anandatheerthavarada HK, Boyd MR, Ravindranath V. Characterization of a phenobarbital-inducible cytochrome-P-450, NADPH-cytochrome P-450 reductase and reconstituted cytochrome-P-450 monooxygenase system from rat-brain: evidence for constitutive presence in rat and human brain. Biochem J 1992;288:483-8.
23. Bhagwat SV, Leelavathi BC, Shankar SK, et al. Cytochrome-P450 and associated monooxygenase activities in the rat and human spinal-cord: induction, immunological characterization and immunocytochemical localization. Neuroscience 1995;68:593-601.
24. Walther B, Ghersiegea JF, Minn A, et al. Subcellular-distribution of cytochrome-P-450 in the brain. Brain Res 1986;375:338-44.
25. Walther B, Ghersiegea JF, Jayyosi Z, et al. Ethoxyresorufin O-deethylase activity in rat-brain subcellular-fractions. Neurosci Lett 1987;76:58-62.
26. Iscan M, Reuhl K, Weiss B, et al. Regional and subcellular-distribution of cytochrome-P-450-dependent drug-metabolism in monkey brain: the olfactory-bulb and the mitochondrial-fractinn have high-levels of activity. Biochem Biophys Res Commun 1990;169:858-63.
27. Bhamre S, Anandatheerthavarada HK, Shankar SK, et al. Microsomal cytochrome P450 in human brain-regions. Biochem Pharmacol 1992;44:1223-5.
28. Ravindranath V, Anandatheerthavarada HK, Shankar SK. Xenobiotic metabolism in human-brain: presence of cytochrome-P-450 and associated mono-oxygenases. Brain Res 1989;496:331-5.
29. Ghersi-Egea JF, Perrin R, Leiningermuller B, et al. Subcellular-localization of cytochrome-P450, and activities of several enzymes responsible for drug-metabolism in the human brain. Biochem Pharmacol 1993;45:647-58.
30. Schilter B, Omiecinski CJ. Regional distribution and expression modulation of cytochrome-P-450 and epoxide hydrolase messenger-RNAs in the rat-brain. Mol Pharmacol 1993;44:990-6.
31. Riedl AG, Watts PM, Edwards RJ, et al. Selective localisation of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera. Brain Res 1996;743:324-328.
32. Farin FM, Omiecinski CJ. Regiospecific expression of cytochrome-P-450s and microsomal epoxide hydrolase in human brain-tissue. J Toxicol Environ Health 1993;40:317-35.
33. Sutter TR, Tang YM, Haves CL, et al. Complete cDNA sequence of a human dioxin-inducible messenger-RNA identifies a new gene subfamily of cytochrome-P450 that maps to chromosome-2. J Biol Chem 1994;269:13092-9.
34. Tang WM, Wo YYP, Stewart J, et al. Isolation and characterization of the human cytochrome-P450 CYP1B1 gene. J Biol Chem 1996;271:28324-30.
35. Shimada T, Haves CL, Yamazaki H, et al. Activation of chemically diverse procarcinogens by human cytochrome-P-450 1B1. Cancer Res 1996;56:2979-84.
36. Otto S, Marcus C, Pidgeon C, et al. A novel adrenocorticotropin-inducible cytochrome P450 from rat adrenal microsomes catalyzes polycyclic aromatic hydrocarbon metabolism. Endocrinology 1991;129:970-81.
37. Hakkola J, Pasanen M, Pelkonen O, et al. Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. Carcinogenesis 1997;18:391-7.
38. Bhattacharyya KK, Brake PB, Eltom SE, et al. Identification of a rat adrenal cytochrome-P450 active in polycyclic-hydrocarbon metabolism as rat CYP1B1: demonstration of a unique tissue-specific pattern of hormonal and arylhydrocarbon receptor-linked regulation. J Biol Chem 1995; 270:11595-602.
39. Walker NJ, Gastel JA, Costa LT, et al. Rat CYP1B1: an adrenal cytochrome-P450 that exhibits sex-dependent expression in livers and kidneys of TCDD-treated animals. Carcinogenesis 1995;16:1319-27.
40. Spink DC, Haves CL, Young NR, et al. The effects of 2,3,7,8-tetrachlorodibenzo-P-dioxin on estrogen metabolism in MCF-7 breast-cancer cells: evidence for induction of a novel 17-beta-estradiol 4-hydroxylase. J Steroid Bioehem Mol Biol 1994;51:251-8.
41. Przedborski S, Levivier M, Jiang H, et al. Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine. Neuroscience 1995;67:631-47.
42. Herkenham M, Little MD, Bankiewicz K, et al. Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study. Neuroscience 1991;40:133-58.
43. Murray GI, Taylor MC, McFadyen MCE, et al. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 1997;57:3026-31.
44. Przedborski S, Levivier M, Jiang H, et al. Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine. Neuscience 1995;67;631-47.
45. + within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study. Neuroscience 1991;40:133-58.
46. Britto M, Pj W. Cytochrome P-450 in the brain. Potential evolutionary and therapeutic relevance of localization of drug-metabolizing enzymes. Drug Metab Disp 1992;20: 446-50.