Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current

Journal of Physiology

Volumn 507, Issue 3, 1998, Pages 771-781

  Gebremedhin, Debebe ^b   Lange, Andrew R ^b   Narayanan, Jayashree ^b   Aebly, Mikael R ^b   Jacobs, Elizabeth R ^b   Harder, David R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CALCIUM CHANNEL; CALCIUM ION; COMPLEMENTARY DNA; CYTOCHROME P450; HYDROXYICOSATETRAENOIC ACID; MESSENGER RNA; NIFEDIPINE; 20 HYDROXYICOSATETRAENOIC ACID; CALCIUM CHANNEL L TYPE; CYTOCHROME P450 4A; CYTOCHROME P450 4A2; CYTOCHROME P450 4A3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY MUSCLE; ARTICLE; BRAIN ARTERY; CALCIUM CURRENT; CAT; CELL TYPE; CONTROLLED STUDY; DEPOLARIZATION; DNA SEQUENCE; FEMALE; MALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ADULT; AMINO ACID METABOLISM; CELL MEMBRANE DEPOLARIZATION; CEREBRAL ARTERY MUSCLE; CONCENTRATION (PARAMETERS); GENE EXPRESSION; HUMAN; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SMOOTH MUSCLE FIBER; VASOCONSTRICTION; WHOLE CELL PATCH CLAMP;

ALKANE 1-MONOOXYGENASE; AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; CATS; CEREBRAL ARTERIES; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; MEMBRANE POTENTIALS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; POLYMERASE CHAIN REACTION; RATS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 0032521122     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.771bs.x     Document Type: Article

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