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Volumn 67, Issue 5, 1996, Pages 2066-2073

Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system

Author keywords

Cerebral cortex; Chlormethiazole; Chlorzoxazone; Ethanol; Hippocampus; Organic solvents

Indexed keywords

ALCOHOL; CHLORZOXAZONE; CLOMETHIAZOLE; CYTOCHROME P450; ORGANIC SOLVENT;

EID: 0029823019     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67052066.x     Document Type: Article
Times cited : (67)

References (42)
  • 3
    • 0027213570 scopus 로고
    • Differential effect of chronic nicotine administration on brain cytochrome P450 1A1/2 and P450 2E1
    • Anandatheerthavarada H. K., Williams J. F., and Wecker L. (1993b) Differential effect of chronic nicotine administration on brain cytochrome P450 1A1/2 and P450 2E1. Biochem. Biophys. Res. Commun. 194, 312-318.
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , pp. 312-318
    • Anandatheerthavarada, H.K.1    Williams, J.F.2    Wecker, L.3
  • 4
    • 0029054656 scopus 로고
    • Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
    • Badger T. M., Ronis M. J. J., Ingelman-Sundberg M., and Hakkak R. (1995) Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions. Eur. J. Biochem. 230, 914-919.
    • (1995) Eur. J. Biochem. , vol.230 , pp. 914-919
    • Badger, T.M.1    Ronis, M.J.J.2    Ingelman-Sundberg, M.3    Hakkak, R.4
  • 5
    • 0025923190 scopus 로고
    • Immunocytochemical staining of the RLM6 form of cytochrome P450 in oligodendrocytes and myelin of rat brain
    • Cammer W., Downing M., Clarke W., and Schenkman J. B. (1991) Immunocytochemical staining of the RLM6 form of cytochrome P450 in oligodendrocytes and myelin of rat brain. J. Histochem. Cytochem. 39, 1089-1094.
    • (1991) J. Histochem. Cytochem. , vol.39 , pp. 1089-1094
    • Cammer, W.1    Downing, M.2    Clarke, W.3    Schenkman, J.B.4
  • 8
    • 0023905495 scopus 로고
    • Transcription of the dystrophin gene in human muscle and non-muscle tissues
    • Chelly J., Kaplan J.-C, Maire P., Gautron S., and Kahn A. (1988) Transcription of the dystrophin gene in human muscle and non-muscle tissues. Nature 333, 858-860.
    • (1988) Nature , vol.333 , pp. 858-860
    • Chelly, J.1    Kaplan, J.-C.2    Maire, P.3    Gautron, S.4    Kahn, A.5
  • 9
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thio-cyanate-phenol-chloroform extraction
    • Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thio-cyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 10
    • 0024546914 scopus 로고
    • Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450
    • Ekström G. and Ingelman-Sundberg M. (1989) Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450. Biochem. Pharmacol. 38, 1313-1319.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1313-1319
    • Ekström, G.1    Ingelman-Sundberg, M.2
  • 11
    • 0023854490 scopus 로고
    • Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures
    • Eliasson E., Johansson I., and Ingelman-Sundberg M. (1988) Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures. Biochem. Biophys. Res. Commun. 150, 436-443.
    • (1988) Biochem. Biophys. Res. Commun. , vol.150 , pp. 436-443
    • Eliasson, E.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 12
    • 0029112792 scopus 로고
    • Rationale for therapy for alcoholic liver disease
    • French S. W. (1995) Rationale for therapy for alcoholic liver disease. Gastroenterology 109, 617-620.
    • (1995) Gastroenterology , vol.109 , pp. 617-620
    • French, S.W.1
  • 13
    • 0028304678 scopus 로고
    • Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics
    • Girre C., Lucas D., Hispard E., Menez C., Dally S., and Menez J.-F. (1994) Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics. Biochem. Pharmacol. 47, 1503-1508.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1503-1508
    • Girre, C.1    Lucas, D.2    Hispard, E.3    Menez, C.4    Dally, S.5    Menez, J.-F.6
  • 14
    • 73049155988 scopus 로고
    • The isolation of nerve endings from brain: An electron-microscopic study of cell fragments derived by homogenization and centrifugation
    • Gray E. G. and Whittaker V. P. (1962) The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. J. Anat. 96, 79-87.
    • (1962) J. Anat. , vol.96 , pp. 79-87
    • Gray, E.G.1    Whittaker, V.P.2
  • 16
    • 0025356936 scopus 로고
    • Regional distribution of cytochrome P-450 2E1 in the rat central nervous system
    • Hansson T., Tindberg N., Ingelman-Sundberg M., and Köhler C. (1990) Regional distribution of cytochrome P-450 2E1 in the rat central nervous system. Neuroscience 34, 451-463.
    • (1990) Neuroscience , vol.34 , pp. 451-463
    • Hansson, T.1    Tindberg, N.2    Ingelman-Sundberg, M.3    Köhler, C.4
  • 18
    • 0027731547 scopus 로고
    • Ethanol-inducible cytochrome P450 2E1: Genetic polymorphism, regulation and possible role in the etiology of alcohol-induced liver disease
    • Ingelman-Sundberg M., Johansson I., Hu Y., Terelius Y., Eliasson E., Clot P., and Albano E. (1993) Ethanol-inducible cytochrome P450 2E1: genetic polymorphism, regulation and possible role in the etiology of alcohol-induced liver disease. Alcohol 10, 447-452.
    • (1993) Alcohol , vol.10 , pp. 447-452
    • Ingelman-Sundberg, M.1    Johansson, I.2    Hu, Y.3    Terelius, Y.4    Eliasson, E.5    Clot, P.6    Albano, E.7
  • 19
    • 0022550277 scopus 로고
    • Hydroxylation of acetone by ethanol- and acetone-inducible cytochrome P-450 in liver microsomes and reconstituted membranes
    • Johansson I., Eliasson E., Norsten C., and Ingelman-Sundberg M. (1986) Hydroxylation of acetone by ethanol- and acetone-inducible cytochrome P-450 in liver microsomes and reconstituted membranes. FEBS Lett. 196, 59-64.
    • (1986) FEBS Lett. , vol.196 , pp. 59-64
    • Johansson, I.1    Eliasson, E.2    Norsten, C.3    Ingelman-Sundberg, M.4
  • 20
    • 0023900010 scopus 로고
    • Ethanol-, fasting- and acetone-inducible cytochromes P450 in the rat liver: Regulation and characteristics of enzymes belonging to the 2B and 2E gene subfamilies
    • Johansson I., Ekström G., Scholte B., Puzycki D., Jörnvall H., and Ingelman-Sundberg M. (1988) Ethanol-, fasting- and acetone-inducible cytochromes P450 in the rat liver: regulation and characteristics of enzymes belonging to the 2B and 2E gene subfamilies. Biochemistry 27, 1925-1934.
    • (1988) Biochemistry , vol.27 , pp. 1925-1934
    • Johansson, I.1    Ekström, G.2    Scholte, B.3    Puzycki, D.4    Jörnvall, H.5    Ingelman-Sundberg, M.6
  • 21
    • 0002255855 scopus 로고
    • Debrisoquine/sparteinemonooxygenase and other P450s in the brain
    • Kalow W., ed, Pergamon Press, New York
    • Kalow W. and Tyndale R. (1992) Debrisoquine/sparteinemonooxygenase and other P450s in the brain, in Pharmacogenetics of Drug Metabolism (Kalow W., ed), pp. 649-656. Pergamon Press, New York.
    • (1992) Pharmacogenetics of Drug Metabolism , pp. 649-656
    • Kalow, W.1    Tyndale, R.2
  • 22
    • 0027515708 scopus 로고
    • Identification of cytochrome P-450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane
    • Kharasch E. D. and Thummel K. E. (1993) Identification of cytochrome P-450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane. Anesthesiology 79, 795-807.
    • (1993) Anesthesiology , vol.79 , pp. 795-807
    • Kharasch, E.D.1    Thummel, K.E.2
  • 23
    • 0022367655 scopus 로고
    • Identification of ethanol-inducible P450 isozyme 3a as the acetone and actetol monooxygenase of rabbit microsomes
    • Koop D. R. and Casazza J. R. (1985) Identification of ethanol-inducible P450 isozyme 3a as the acetone and actetol monooxygenase of rabbit microsomes. J. Biol. Chem. 260, 13607-13612.
    • (1985) J. Biol. Chem. , vol.260 , pp. 13607-13612
    • Koop, D.R.1    Casazza, J.R.2
  • 24
    • 0027164207 scopus 로고
    • Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol inducible cytochrome P450 2E1
    • Laethem R. M., Balazy M., Falck J. R., Laethem C. L., and Koop D. R. (1993) Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol inducible cytochrome P450 2E1. J. Biol. Chem. 268, 12912-12918.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12912-12918
    • Laethem, R.M.1    Balazy, M.2    Falck, J.R.3    Laethem, C.L.4    Koop, D.R.5
  • 26
    • 0019638515 scopus 로고
    • Growth of purified astrocytes in a chemically defined medium
    • Morrison R. S. and de Vellis J. (1981) Growth of purified astrocytes in a chemically defined medium. Proc. Natl. Acad. Sci. USA 78, 7205-7209.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7205-7209
    • Morrison, R.S.1    De Vellis, J.2
  • 31
    • 0028641564 scopus 로고
    • Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less
    • Roberts B. J., Shoaf S. E., Jeong K.-S., and Song B. J. (1994) Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less. Biochem. Biophys. Res. Commun. 205, 1064-1071.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1064-1071
    • Roberts, B.J.1    Shoaf, S.E.2    Jeong, K.-S.3    Song, B.J.4
  • 35
    • 0023645414 scopus 로고
    • Isolation and catalytic activity of cytochrome P-450 from ventral prostate of control rats
    • Sundin M., Warner M., Haaparanta T., and Gustafsson J.-Å. (1987) Isolation and catalytic activity of cytochrome P-450 from ventral prostate of control rats. J. Biol. Chem. 262, 12293-12297.
    • (1987) J. Biol. Chem. , vol.262 , pp. 12293-12297
    • Sundin, M.1    Warner, M.2    Haaparanta, T.3    Gustafsson, J.-Å.4
  • 37
    • 0024386439 scopus 로고
    • Cytochrome P-450 and oxygen toxicity. Oxygen-dependent induction of CYP2E1 in rat liver and lung
    • Tindberg N. and Ingelman-Sundberg M. (1989) Cytochrome P-450 and oxygen toxicity. Oxygen-dependent induction of CYP2E1 in rat liver and lung. Biochemistry 28, 4499-4504.
    • (1989) Biochemistry , vol.28 , pp. 4499-4504
    • Tindberg, N.1    Ingelman-Sundberg, M.2
  • 38
    • 0000858780 scopus 로고
    • Extrahepatic microsomal forms: Brain cytochrome P-450
    • Schenkmann J. B., ed, Springer Verlag, Berlin
    • Warner M. and Gustafsson J.-Å. (1993) Extrahepatic microsomal forms: brain cytochrome P-450, in Cytochrome P-450 - A Handbook (Schenkmann J. B., ed), pp. 387-397. Springer Verlag, Berlin.
    • (1993) Cytochrome P-450 - A Handbook , pp. 387-397
    • Warner, M.1    Gustafsson, J.-Å.2
  • 39
    • 0028118901 scopus 로고
    • Effect of ethanol on cytochrome P-450 in the rat brain
    • Warner M. and Gustafsson J.-Å. (1994) Effect of ethanol on cytochrome P-450 in the rat brain. Proc. Natl. Acad. Sci. USA 91, 1019-1023.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1019-1023
    • Warner, M.1    Gustafsson, J.-Å.2
  • 40
    • 0025099248 scopus 로고
    • Oxidation of glycerol to formaldehyde by rat liver microsomes
    • Winters D. K. and Cederbaum A. I. (1990) Oxidation of glycerol to formaldehyde by rat liver microsomes. Biochem. Pharmacol. 39, 697-705.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 697-705
    • Winters, D.K.1    Cederbaum, A.I.2
  • 41
    • 0028918999 scopus 로고
    • Selectivity of cytochrome P450 2E1 in chlorzoxazone 6-hydroxylation
    • Yamazaki H., Guo Z., and Guengerich F. P. (1995) Selectivity of cytochrome P450 2E1 in chlorzoxazone 6-hydroxylation. Drug Metab. Dispos. 23, 438-440.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 438-440
    • Yamazaki, H.1    Guo, Z.2    Guengerich, F.P.3
  • 42
    • 0027250201 scopus 로고
    • Identification of the major cytochrome P450s of subfamily 2C that are expressed in brain of female rats and in olfactory lobes of ethanol treated male rats
    • Zaphiropoulos P. G. and Wood T. (1993) Identification of the major cytochrome P450s of subfamily 2C that are expressed in brain of female rats and in olfactory lobes of ethanol treated male rats. Biochem. Biaphys. Res. Commun. 193, 1006-1013.
    • (1993) Biochem. Biaphys. Res. Commun. , vol.193 , pp. 1006-1013
    • Zaphiropoulos, P.G.1    Wood, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.