Effect of cytochrome P450 1A induction on oxidative damage in rat brain

Molecular and Cellular Biochemistry

Volumn 223, Issue 1-2, 2001, Pages 89-94

  Liu, L ^a   Bridges, R J ^a   Eyer, C L ^a  

^a UNIVERSITY OF MONTANA   (United States)

Author keywords

3 methylcholanthrene (3 MC); Cytochrome P450 1A induction; Glutamine synthetase; Oxidative damage; Rat brain

Indexed keywords

3 METHYLCHOLANTHRENE; ANTIOXIDANT; CYTOCHROME P450 1A1; ETHOXYRESORUFIN DEETHYLASE; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; HALOGENATED HYDROCARBON; POLYCYCLIC AROMATIC HYDROCARBON; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FLUORESCENCE; HOMEOSTASIS; IN VIVO STUDY; LIPID OXIDATION; LIVER LEVEL; MALE; MEASUREMENT; NONHUMAN; OXIDATIVE STRESS; RAT; TIME;

ANIMALS; BIOLOGICAL MARKERS; BRAIN; CYTOCHROME P-450 CYP1A1; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; ISOENZYMES; LIVER; MALE; METHYLCHOLANTHRENE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0034799622     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017904912654     Document Type: Article

References (30)

1. Signal transduction in environmental neurotoxicity
2. The aryl hydrocarbon receptor complex
3. Mechanism of signal transduction by the basic helix-loop-helix dioxin receptor
4. Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain
5. Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver
6. Oxidative stress in neurodegenerative diseases
7. Oxidants and the central nervous system: Some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?
8. Glutamate neurotoxicity and diseases of the nervous system
9. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain
10. Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes
11. Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic alcohol consumption
12. Ethanol increases cytochrome P450 2E1 and induces oxidative stress in astrocytes
13. Interrelation of oxygen anion-radical generation and lipid peroxidation in liver microsomes
14. Induction of cytochrome P450 1A by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin or indolo (3, 2-b) carbazole is associated with oxidative DNA damage
15. Cytochrome P-450 dependent monooxygenases in neuronal and glial cells: Inducibility and specificity
16. Biochemical effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds on the central nervous system
17. Induction of CYP1A by beta-naphthoflavone in IEC-18 rat intestinal epithelial cells and potentiation of induction by dibutyryl cAMP
18. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced ethoxyresorufin-O-deethylase (EROD) and aldehyde dehydrogenase (ALDH3) activities in the brain and liver. A comparison between the most rat strain
19. Microsomal lipid peroxidation
20. Protein damage and degradation by oxygen radicals. II. Modification of amino acids
21. Glutamine synthetase from mammalian tissues
22. The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation
23. Expression, induction and regulation of the cytochrome P450 monooxygenase system in the rat glioma C6 cell line
24. Environmental occurrence, abundance, and potential toxicity of polychlorinated biphenyl congeners: Considerations for a congener-specific analysis
25. Effect of phenobarbital or 3-methylcholanthrene pretreatment on carbon tetrachloride-induced lipid peroxidation in rat liver
26. Alcohol and antioxidant systems
27. Purification of a protease from Escherichia coli with specificity for oxidized glutamine synthetase
28. Fine structural localization of glutamine synthetase in astrocytes of rat brain
29. Antioxidant defense of the brain: A role for astrocytes
30. Distribution and induction of cytochrome P450 1A1 and 1A2 in the rat brain