Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

Journal of Biological Chemistry

Volumn 277, Issue 44, 2002, Pages 41326-41333

  Haimeur, Anass ^a   Deeley, Roger G ^a   Cole, Susan P C ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; CELLS; HYDROGEN BONDS; NEGATIVE IONS; PROTEINS;

MULTIDRUG RESISTANCE;

BIOCHEMISTRY;

ABC TRANSPORTER; AMINO ACID; APIGENIN; ESTRADIOL; ESTRONE SULFATE; LEUKOTRIENE C4; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTER;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; HYDROGEN BOND; KIDNEY CELL; KINETICS; MEMBRANE TRANSPORT; MEMBRANE VESICLE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CELL MEMBRANE; ESTRADIOL; ESTRONE; GLUTATHIONE; HUMANS; LEUKOTRIENE C4; METHOTREXATE; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0036828695     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206228200     Document Type: Article

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