Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport

Cancer Research

Volumn 61, Issue 19, 2001, Pages 7225-7232

  Zeng, Hao ^a   Chen, Zhe Sheng ^a   Belinsky, Martin G ^a   Rea, Philip A ^b   Kruh, Gary D ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4,6 DIMETHYL 1,3,2 DIOXAPHOSPHORINAN 2 YL) 2,6 DIMETHYL 4 (3 NITROPHENYL) 3 PYRIDINECARBOXYLIC ACID 2 (4 BENZHYDRYL 1 PIPERAZINYL)ETHYL ESTER P OXIDE; ANTIMETABOLITE; DOXORUBICIN; ETOPOSIDE; FOLIC ACID ANTAGONIST; FOLIC ACID DERIVATIVE; FOLINIC ACID; GLUTATHIONE; GLYCOCHOLIC ACID; METHOTREXATE; METHOTREXATE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; PRANLUKAST; PROBENECID; RALTITREXED; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; VALSPODAR; VERAPAMIL; VERLUKAST; VINCRISTINE;

ANIMAL CELL; ARTICLE; CANCER; CANCER CHEMOTHERAPY; CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG TRANSPORT; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; DRUG RESISTANCE, MULTIPLE; FOLIC ACID; HUMANS; LEUCOVORIN; METHOTREXATE; MICE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OSMOLAR CONCENTRATION; POLYGLUTAMIC ACID; TRITIUM;

EID: 0035476729     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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