-
1
-
-
0033610801
-
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain
-
Bakos E, Evers R, Szakacs G, Tusnady GE, Welker E, Szabo K, de Haas M, van Deemter L, Borst P, Varadi A, Sarkadi B 1998 Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. J Biol Chem 273: 32167-32175
-
(1998)
J Biol Chem
, vol.273
, pp. 32167-32175
-
-
Bakos, E.1
Evers, R.2
Szakacs, G.3
Tusnady, G.E.4
Welker, E.5
Szabo, K.6
De Haas, M.7
Van Deemter, L.8
Borst, P.9
Varadi, A.10
Sarkadi, B.11
-
2
-
-
0030014846
-
Membrane topology and glycosylation of the human multidrug resistance-associated protein
-
Bakos E, Hegedus T, Rollo Z, Welker E, Tusnady GE, Zaman GJ, Flens MJ, Paradi A, Sarkadi B 1996 Membrane topology and glycosylation of the human multidrug resistance-associated protein. J Biol Chem 271: 12322-12326
-
(1996)
J Biol Chem
, vol.271
, pp. 12322-12326
-
-
Bakos, E.1
Hegedus, T.2
Rollo, Z.3
Welker, E.4
Tusnady, G.E.5
Zaman, G.J.6
Flens, M.J.7
Paradi, A.8
Sarkadi, B.9
-
3
-
-
0031965130
-
Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione
-
Barnouin K, Leier I, Jedlitschky G, Pourtier-Manzanedo A. König J, Lehmann WD, Keppler D 1998 Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione. Br J Cancer 77: 201-209
-
(1998)
Br J Cancer
, vol.77
, pp. 201-209
-
-
Barnouin, K.1
Leier, I.2
Jedlitschky, G.3
Pourtier-Manzanedo, A.4
König, J.5
Lehmann, W.D.6
Keppler, D.7
-
4
-
-
0031715907
-
Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump
-
Bartosz G, König J, Keppler D, Hagmann W 1998 Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump. Biol Chem 379: 1121-1126
-
(1998)
Biol Chem
, vol.379
, pp. 1121-1126
-
-
Bartosz, G.1
König, J.2
Keppler, D.3
Hagmann, W.4
-
5
-
-
0023748077
-
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine
-
Beck WT, Cirtain MC, Glover CJ, Felsted RL, Safa AR 1988 Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine. Biochem Biophys Res Commun 153: 959-966
-
(1988)
Biochem Biophys Res Commun
, vol.153
, pp. 959-966
-
-
Beck, W.T.1
Cirtain, M.C.2
Glover, C.J.3
Felsted, R.L.4
Safa, A.R.5
-
6
-
-
0031158790
-
Do cMOAT (MRP2), other MRP homologues, and LRP play a role in MDR?
-
Borst P, Kool M, Evers R 1997 Do cMOAT (MRP2), other MRP homologues, and LRP play a role in MDR? Semin Cancer Biol 8: 205-213
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 205-213
-
-
Borst, P.1
Kool, M.2
Evers, R.3
-
8
-
-
0025366661
-
Chemistry and biology of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids: Fluorescent probes of biological and model membranes
-
Chattopadhyay A 1990 Chemistry and biology of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids: fluorescent probes of biological and model membranes. Chem Phys Lipids 53: 1-15
-
(1990)
Chem Phys Lipids
, vol.53
, pp. 1-15
-
-
Chattopadhyay, A.1
-
9
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EV, Duncan AM, Deeley RG 1992 Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258: 1650-1654
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.V.8
Duncan, A.M.9
Deeley, R.G.10
-
10
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C, O'Brien JP, Casals D, Rittman-Grauer L, Biedler A, Melamed MR, Bertino A 1989 Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci USA 86: 695-698
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, A.5
Melamed, M.R.6
Bertino, A.7
-
11
-
-
0032553014
-
Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: Outward-directed transport by the multidrug resistance protein 1 (MRP1)
-
Dekkers DW, Comfurius P, Schroit AJ, Bevers EM, Zwaal RF 1998 Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1). Biochemistry 37: 14833-14837
-
(1998)
Biochemistry
, vol.37
, pp. 14833-14837
-
-
Dekkers, D.W.1
Comfurius, P.2
Schroit, A.J.3
Bevers, E.M.4
Zwaal, R.F.5
-
12
-
-
0026636418
-
Protein involvement in transmembrane lipid asymmetry
-
Devaux PF 1992 Protein involvement in transmembrane lipid asymmetry. Annu Rev Biophys Biomol Struct 21: 417-439
-
(1992)
Annu Rev Biophys Biomol Struct
, vol.21
, pp. 417-439
-
-
Devaux, P.F.1
-
13
-
-
0031449603
-
Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1
-
Evers R, Cnubben NH, Wijnholds J, van Deemter L, van Bladeren PJ, Borst P 1997 Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1. FEBS Lett 419: 112-116
-
(1997)
FEBS Lett
, vol.419
, pp. 112-116
-
-
Evers, R.1
Cnubben, N.H.2
Wijnholds, J.3
Van Deemter, L.4
Van Bladeren, P.J.5
Borst, P.6
-
14
-
-
0031695039
-
Blood-brain barrier permeation: Molecular parameters governing passive diffusion
-
Fischer H, Gottschlich R. Seelig A 1998 Blood-brain barrier permeation: molecular parameters governing passive diffusion. J Membr Biol 165: 201-211
-
(1998)
J Membr Biol
, vol.165
, pp. 201-211
-
-
Fischer, H.1
Gottschlich, R.2
Seelig, A.3
-
15
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM, Pastan I 1993 Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62: 385-427
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
16
-
-
0022993652
-
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
-
Cros P, Croop J, Housman D 1986 Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 47: 371-380
-
(1986)
Cell
, vol.47
, pp. 371-380
-
-
Cros, P.1
Croop, J.2
Housman, D.3
-
18
-
-
0030863293
-
Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus
-
Hipfner DR, Almquist KC, Leslie EM, Gerlach JH, Grant CE, Deeley RG, Cole SP 1997 Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus. J Biol Chem 272: 23623-23630
-
(1997)
J Biol Chem
, vol.272
, pp. 23623-23630
-
-
Hipfner, D.R.1
Almquist, K.C.2
Leslie, E.M.3
Gerlach, J.H.4
Grant, C.E.5
Deeley, R.G.6
Cole, S.P.7
-
19
-
-
0030668526
-
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepalocyte canalicular isoform MRP2
-
Jedlitschky G, Leier I, Buchholz U, Hummel-Eisenbeiss J, Burchell B, Keppler D 1997 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepalocyte canalicular isoform MRP2. Biochem J 327: 305-310
-
(1997)
Biochem J
, vol.327
, pp. 305-310
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Hummel-Eisenbeiss, J.4
Burchell, B.5
Keppler, D.6
-
20
-
-
0032562137
-
Epitope insertion favors a six-transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein
-
Kast C, Gros P 1998 Epitope insertion favors a six-transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein. Biochemistry 37: 2305-2313
-
(1998)
Biochemistry
, vol.37
, pp. 2305-2313
-
-
Kast, C.1
Gros, P.2
-
21
-
-
0030752006
-
Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2
-
Keppler D, Leier I, Jedlitschky G 1997 Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2. Biol Chem 378: 787-791
-
(1997)
Biol Chem
, vol.378
, pp. 787-791
-
-
Keppler, D.1
Leier, I.2
Jedlitschky, G.3
-
22
-
-
0027415179
-
Progesterone regulates the murine multidrug resistance mdr1b gene
-
Piekarz RL, Cohen D, Horwitz SB 1993 Progesterone regulates the murine multidrug resistance mdr1b gene. J Biol Chem 268: 7613-7616
-
(1993)
J Biol Chem
, vol.268
, pp. 7613-7616
-
-
Piekarz, R.L.1
Cohen, D.2
Horwitz, S.B.3
-
23
-
-
0032577901
-
Doxorubicin-and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump
-
Priebe W, Krawczyk M, Kuo MT, Yamane Y, Savaraj N, Ishikawa T 1998 Doxorubicin-and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump. Biochem Biophys Res Commun 247: 859-863
-
(1998)
Biochem Biophys Res Commun
, vol.247
, pp. 859-863
-
-
Priebe, W.1
Krawczyk, M.2
Kuo, M.T.3
Yamane, Y.4
Savaraj, N.5
Ishikawa, T.6
-
24
-
-
0033058419
-
The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane
-
Raggers RJ, van Helvoort A, Evers R, van Meer G 1999 The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane. J Cell Sci 112: 415-422
-
(1999)
J Cell Sci
, vol.112
, pp. 415-422
-
-
Raggers, R.J.1
Van Helvoort, A.2
Evers, R.3
Van Meer, G.4
-
25
-
-
0032509502
-
ATP-dependent transport of reduced glutathione on YCR. The yeast orthologue of mammalian multidrug resistance-associated proteins
-
Rebbeor JF, Connolly GC, Dumont ME, Ballatori N 1998 ATP-dependent transport of reduced glutathione on YCR. the yeast orthologue of mammalian multidrug resistance-associated proteins. J Biol Chem 273: 33449-33454
-
(1998)
J Biol Chem
, vol.273
, pp. 33449-33454
-
-
Rebbeor, J.F.1
Connolly, G.C.2
Dumont, M.E.3
Ballatori, N.4
-
26
-
-
0032472791
-
Effects of cardiovascular drugs on ATPase activity of P-glycoprotein in plasma membranes and in purified reconstituted form
-
Rebbeor JF, Senior AE 1998 Effects of cardiovascular drugs on ATPase activity of P-glycoprotein in plasma membranes and in purified reconstituted form. Biochim Biophys Acta 1369: 85-93
-
(1998)
Biochim Biophys Acta
, vol.1369
, pp. 85-93
-
-
Rebbeor, J.F.1
Senior, A.E.2
-
27
-
-
0014062165
-
Use of helical wheels to represent the structures of proteins and to identify segments with helical potential
-
Schiffer M, Edmundson AB 1967 Use of helical wheels to represent the structures of proteins and to identify segments with helical potential. Biophys J 7: 121-135
-
(1967)
Biophys J
, vol.7
, pp. 121-135
-
-
Schiffer, M.1
Edmundson, A.B.2
-
28
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CA, van Deemter L 1996 P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 97: 2517-2524
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Van Deemter, L.4
-
29
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinated up-regulate these proteins in human colon carcinoma cells
-
Schuetz EC, Beck WT, Schuetz JD 1996 Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinated up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 49: 311-318
-
(1996)
Mol Pharmacol
, vol.49
, pp. 311-318
-
-
Schuetz, E.C.1
Beck, W.T.2
Schuetz, J.D.3
-
30
-
-
0032518454
-
A general pattern for substrate recognition by P-glycoprotein
-
Seelig A 1998 A general pattern for substrate recognition by P-glycoprotein. Eur J Biochem 251: 252-261
-
(1998)
Eur J Biochem
, vol.251
, pp. 252-261
-
-
Seelig, A.1
-
31
-
-
0031821697
-
Uncouplers of mitochondrial oxidative phosphorylation are not substrates of the erythrocyte glutathione-S-conjugate pump
-
Sokal A, Bartosz G 1998 Uncouplers of mitochondrial oxidative phosphorylation are not substrates of the erythrocyte glutathione-S-conjugate pump. Arch Biochem Biophys 349: 113-121
-
(1998)
Arch Biochem Biophys
, vol.349
, pp. 113-121
-
-
Sokal, A.1
Bartosz, G.2
-
32
-
-
0031780225
-
Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel
-
Su GM, Davey MW, Davey RA 1998 Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel. Int J Cancer 76: 702-708
-
(1998)
Int J Cancer
, vol.76
, pp. 702-708
-
-
Su, G.M.1
Davey, M.W.2
Davey, R.A.3
-
33
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC 1987 Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84: 7735-7738
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
34
-
-
0007544439
-
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
-
van Helvoort A, Smith AJ, Sprong H, Fritzsche I, Schinkel AH, Borst P, van Meer G 1996 MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 87: 507-517
-
(1996)
Cell
, vol.87
, pp. 507-517
-
-
Van Helvoort, A.1
Smith, A.J.2
Sprong, H.3
Fritzsche, I.4
Schinkel, A.H.5
Borst, P.6
Van Meer, G.7
-
36
-
-
0028901538
-
Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1
-
Zhang X, Collins KI, Greenberger LM 1995 Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1. J Biol Chem 270: 5441-5448
-
(1995)
J Biol Chem
, vol.270
, pp. 5441-5448
-
-
Zhang, X.1
Collins, K.I.2
Greenberger, L.M.3
-
37
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-pi binding site in the nicotinic receptor
-
Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA 1998 From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc Natl Acad Sci USA 95: 12088-12093
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
Gallivan, J.P.2
Zhang, Y.3
Li, L.4
Lester, H.A.5
Dougherty, D.A.6
|