메뉴 건너뛰기




Volumn 27, Issue 1, 1997, Pages 96-102

Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients

Author keywords

Aging; Alcoholism; DNA; Mitochondria; Mutations; Steatosis

Indexed keywords

ALCOHOL; DNA; LIPID; MITOCHONDRIAL DNA; NUCLEOTIDE; PROTEIN; REACTIVE OXYGEN METABOLITE;

EID: 0030806434     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80286-3     Document Type: Article
Times cited : (140)

References (20)
  • 2
    • 0016327931 scopus 로고
    • The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells
    • Bogenhagen D, Clayton DA. The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. J Biol Chem. 249:1974;7991-7995.
    • (1974) J Biol Chem , vol.249 , pp. 7991-7995
    • Bogenhagen, D.1    Clayton, D.A.2
  • 3
    • 0026732706 scopus 로고
    • A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
    • Cortopassi GA, Shibata D, Soong NW, Arnheim N. A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci USA. 89:1992;7370-7374.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7370-7374
    • Cortopassi, G.A.1    Shibata, D.2    Soong, N.W.3    Arnheim, N.4
  • 4
    • 0026587335 scopus 로고
    • Mitochondrial genetics: A paradigm for aging and degenerative diseases
    • Wallace DC. Mitochondrial genetics: a paradigm for aging and degenerative diseases. Science. 256:1992;628-632.
    • (1992) Science , vol.256 , pp. 628-632
    • Wallace, D.C.1
  • 6
    • 0003054810 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations and aging
    • N.J. Holbrook, G.R. Martin, Lockshin R.A. New York: John Wiley and Sons
    • Schon EA, Sciacco M, Pallotti F, Chen X, Bonilla E. Mitochondrial DNA mutations and aging. Holbrook NJ, Martin GR, Lockshin RA. Cellular aging and cell death. 19:1996;34 John Wiley and Sons, New York.
    • (1996) Cellular Aging and Cell Death , vol.19 , pp. 34
    • Schon, E.A.1    Sciacco, M.2    Pallotti, F.3    Chen, X.4    Bonilla, E.5
  • 7
    • 0029029471 scopus 로고
    • Modelling the effect of age-related mtDNA mutation accumulation; Complex I deficiency, superoxide and cell death
    • Cortopassi G, Wang E. Modelling the effect of age-related mtDNA mutation accumulation; Complex I deficiency, superoxide and cell death. Biochim Biophys Acta. 1271:1995;171-176.
    • (1995) Biochim Biophys Acta , vol.1271 , pp. 171-176
    • Cortopassi, G.1    Wang, E.2
  • 9
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
    • Fromenty B, Pessayre D. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther. 67:1995;101-154.
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 10
    • 0028332490 scopus 로고
    • Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment
    • Kukielka E, Dicker E, Cederbaum AI. Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment. Arch Biochem Biophys. 309:1994;377-386.
    • (1994) Arch Biochem Biophys , vol.309 , pp. 377-386
    • Kukielka, E.1    Dicker, E.2    Cederbaum, A.I.3
  • 12
    • 0025979356 scopus 로고
    • Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress
    • Fernandez-Checa JC, Garcia-Ruiz C, Ookhtens M, Kaplowitz N. Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress. J Clin Invest. 87:1991;397-405.
    • (1991) J Clin Invest , vol.87 , pp. 397-405
    • Fernandez-Checa, J.C.1    Garcia-Ruiz, C.2    Ookhtens, M.3    Kaplowitz, N.4
  • 13
    • 0029093010 scopus 로고
    • Oxidation of mitochondrial proteins and DNA following administration of ethanol
    • Wieland P, Lauterburg BH. Oxidation of mitochondrial proteins and DNA following administration of ethanol. Biochem Biophys Res Commun. 213:1995;815-819.
    • (1995) Biochem Biophys Res Commun , vol.213 , pp. 815-819
    • Wieland, P.1    Lauterburg, B.H.2
  • 14
    • 0023672576 scopus 로고
    • Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cells
    • Grosovsky AJ, De Boer JG, De Jong PJ, Drobetsky EA, Glickman BW. Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cells. Proc Natl Acad Sci USA. 85:1988;185-188.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 185-188
    • Grosovsky, A.J.1    De Boer, J.G.2    De Jong, P.J.3    Drobetsky, E.A.4    Glickman, B.W.5
  • 15
    • 0026554148 scopus 로고
    • Implication of free radical mechanisms in ethanol-induced cellular injury
    • Nordmann R, Ribière C, Rouach H. Implication of free radical mechanisms in ethanol-induced cellular injury. Free Rad Biol Med. 12:1992;219-240.
    • (1992) Free Rad Biol Med , vol.12 , pp. 219-240
    • Nordmann, R.1    Ribière, C.2    Rouach, H.3
  • 16
    • 0021280363 scopus 로고
    • Biochemical and morphological alterations of baboon hepatic mitochondria after chronic ethanol consumption
    • Arai M, Leo MA, Nakano M, Gordon ER, Lieber CS. Biochemical and morphological alterations of baboon hepatic mitochondria after chronic ethanol consumption. Hepatology. 4:1984;165-174.
    • (1984) Hepatology , vol.4 , pp. 165-174
    • Arai, M.1    Leo, M.A.2    Nakano, M.3    Gordon, E.R.4    Lieber, C.S.5
  • 17
    • 0025002623 scopus 로고
    • Effects of chronic ethanol consumption on the synthesis of polypeptides encoded by the hepatic mitochondrial genome
    • Coleman WB, Cunningham CC. Effects of chronic ethanol consumption on the synthesis of polypeptides encoded by the hepatic mitochondrial genome. Biochim Biophys Acta. 1019:1990;142-150.
    • (1990) Biochim Biophys Acta , vol.1019 , pp. 142-150
    • Coleman, W.B.1    Cunningham, C.C.2
  • 18
    • 0019861924 scopus 로고
    • Molecular alterations in the respiratory chain of rat liver after chronic ethanol consumption
    • Thayer WS, Rubin E. Molecular alterations in the respiratory chain of rat liver after chronic ethanol consumption. J Biol Chem. 256:1981;6090-6097.
    • (1981) J Biol Chem , vol.256 , pp. 6090-6097
    • Thayer, W.S.1    Rubin, E.2
  • 20
    • 0028350236 scopus 로고
    • Increased risk of hepatocellular carcinoma development in patients with cirrhosis and with high hepatocellular proliferation
    • Ballardini G, Groff P, Zoli M, Bianchi GP, Giostra F, Francesconi R, et al. Increased risk of hepatocellular carcinoma development in patients with cirrhosis and with high hepatocellular proliferation. J Hepatol. 20:1994;218-222.
    • (1994) J Hepatol , vol.20 , pp. 218-222
    • Ballardini, G.1    Groff, P.2    Zoli, M.3    Bianchi, G.P.4    Giostra, F.5    Francesconi, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.