Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency

Journal of Clinical Investigation

Volumn 99, Issue 12, 1997, Pages 2877-2882

  Luo, Xiaoping ^a   Pitkänen, Sari ^b,c   Kassovska Bratinova, Sacha ^b,c   Robinson, Brian H ^b,c   Lehotay, Denis C ^a,c  

^a Division of Orthopedics   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

Cardiomyopathy; Cataracts; Complex I deficiency; Hydroxyl radicals; Lipid peroxidation

Indexed keywords

1 HYDROXY 1 PHENYL 2 PROPANONE; 4 HYDROXYNONENAL; ALDEHYDE; DOXORUBICIN; HEXANAL; HYDROXYL RADICAL; MALONALDEHYDE; MENADIONE; UNCLASSIFIED DRUG;

ARTICLE; CARDIOMYOPATHY; CATARACT; CELL CULTURE; CONTROLLED STUDY; ENZYME DEFICIENCY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; PRIORITY JOURNAL; SKIN FIBROBLAST;

EID: 1842338036     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119481     Document Type: Article

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