Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase

Biochemical Journal

Volumn 365, Issue 3, 2002, Pages 765-772

  Kim, Hyunggee ^a   Farris, James ^a   Christman, Shelly A ^a   Kong, Byung Whi ^a   Foster, Linda K ^a   O'Grady, Scott M ^a   Foster, Douglas N ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Immortalization; Myc; p16INK4a; p53

Indexed keywords

CATALYSIS; DNA; ENZYMES;

GENETIC ALTERATIONS;

CELLS;

BETA GALACTOSIDASE; PROTEIN P16; PROTEIN P53; TELOMERASE; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

ARTICLE; BREAST EPITHELIUM; CELL IMMORTALIZATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ONCOGENE C MYC; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TELOMERE;

ANIMALS; BREAST; CATALYTIC DOMAIN; CELL AGING; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; GENES, MYC; GENES, P16; GENES, P53; HUMANS; MIDDLE AGED; TELOMERASE; TELOMERE; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036684533     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20011848     Document Type: Article

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