-
2
-
-
0034626735
-
Oxidants, oxidative stress and the biology of aging
-
Finkel T, Holbrook NJ: Oxidants, oxidative stress and the biology of aging. Nature 2000, 408: 239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
3
-
-
0034626769
-
The age of cancer
-
DePinho RA: The age of cancer. Nature 2000, 408: 248-254.
-
(2000)
Nature
, vol.408
, pp. 248-254
-
-
Depinho, R.A.1
-
4
-
-
0034626747
-
Genetic pathways that regulate aging in model organisms
-
Guarente L, Kenyon C: Genetic pathways that regulate aging in model organisms. Nature 2000, 408: 255-262.
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
5
-
-
0034626770
-
Lessons from human progeroid syndromes
-
Martin GM, Oshima J: Lessons from human progeroid syndromes. Nature 2000, 408: 263-266.
-
(2000)
Nature
, vol.408
, pp. 263-266
-
-
Martin, G.M.1
Oshima, J.2
-
6
-
-
0034626766
-
The future of ageing
-
Hayflick L: The future of ageing. Nature 2000, 408: 267-269.
-
(2000)
Nature
, vol.408
, pp. 267-269
-
-
Hayflick, L.1
-
8
-
-
0000055057
-
Pleitrophy, natural selection and the evolution of senescence
-
Williams GC: Pleitrophy, natural selection and the evolution of senescence. Evolutions 1957, 11: 398-411.
-
(1957)
Evolutions
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
9
-
-
0030016821
-
Longevity, genes and aging
-
Jazwinski SM: Longevity, genes and aging. Science 1996, 273: 54-59.
-
(1996)
Science
, vol.273
, pp. 54-59
-
-
Jazwinski, S.M.1
-
12
-
-
0026314114
-
Evolution of senescence: Late survival sacrificed for reproduction
-
Kirkwood TB, Rose MR: Evolution of senescence: late survival sacrificed for reproduction. Philos Trans R Soc Lond B Biol Sci 1991, 332: 15-24.
-
(1991)
Philos Trans R Soc Lond B Biol Sci
, vol.332
, pp. 15-24
-
-
Kirkwood, T.B.1
Rose, M.R.2
-
13
-
-
0030782088
-
The evolution of human longevity
-
Holliday R: The evolution of human longevity. Perspect Biol Med 1996, 40: 100-107.
-
(1996)
Perspect Biol Med
, vol.40
, pp. 100-107
-
-
Holliday, R.1
-
14
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn EH: Structure and function of telomeres. Nature 1991, 350: 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
15
-
-
0015844590
-
A theory of marginotomy: The incomplete copying of template margin in enzymic synthesis of pronucleotides and biological significance of the phenomenon
-
Olovnikov AM: A theory of marginotomy: the incomplete copying of template margin in enzymic synthesis of pronucleotides and biological significance of the phenomenon. J Theor Biol 1973, 41: 181-190.
-
(1973)
J Theor Biol
, vol.41
, pp. 181-190
-
-
Olovnikov, A.M.1
-
16
-
-
0015515155
-
Origin of concatemeric T7 DNA
-
Watson JD: Origin of concatemeric T7 DNA. Nature New Biol 1972, 239: 197-201.
-
(1972)
Nature New Biol
, vol.239
, pp. 197-201
-
-
Watson, J.D.1
-
17
-
-
0026735646
-
Telomere end-replication problem and cell aging
-
Levy MZ, Allsopp RC, Futcher AB, et al.: Telomere end-replication problem and cell aging. J Mol Biol 1992, 225: 951-960.
-
(1992)
J Mol Biol
, vol.225
, pp. 951-960
-
-
Levy, M.Z.1
Allsopp, R.C.2
Futcher, A.B.3
-
18
-
-
0022402513
-
Identification of a specific telomere terminal transferase enzyme with two kinds of primer specificity
-
Greider CW, Blackburn EH: Identification of a specific telomere terminal transferase enzyme with two kinds of primer specificity. Cell 1985, 51: 405-413.
-
(1985)
Cell
, vol.51
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
19
-
-
0024325562
-
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
-
Morin GB: The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 1989, 59: 521-529.
-
(1989)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.B.1
-
20
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura TM, Morin GB, Chapman KB, et al.: Telomerase catalytic subunit homologs from fission yeast and human. Science 1997, 277: 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
-
21
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk WD, Wang S-S, et al.: The RNA component of human telomerase. Science 1995, 269: 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.-S.3
-
22
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp RC, Vaziri H, Patterson C, et al.: Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A 1992, 89: 10114-10118.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
-
23
-
-
0028856794
-
Telomere length and replicative aging in human vascular tissues
-
Chang E, Harley CB: Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci U S A 1995, 92: 11190-11194.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11190-11194
-
-
Chang, E.1
Harley, C.B.2
-
24
-
-
8944258925
-
Shortened telomeres in the expanded CD28- CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
-
Effros RB, Allsopp R, Chiu C-P, et al.: Shortened telomeres in the expanded CD28-CD8+T cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 1996, 10:F17-F22. (Pubitemid 26229506)
-
(1996)
AIDS
, vol.10
, Issue.8
-
-
Effros, R.B.1
Allsopp, R.2
Chiu, C.-P.3
Hausner, M.A.4
Hirji, K.I.5
Wang, L.6
Harley, C.B.7
Villeponteau, B.8
West, M.D.9
Giorgi, J.V.10
-
25
-
-
0026628668
-
The telomere hypothesis of cellular aging
-
Harley CB, Vaziri H, Counter CM, et al.: The telomere hypothesis of cellular aging. Exp Gerontol 1992, 27: 375-382.
-
(1992)
Exp Gerontol
, vol.27
, pp. 375-382
-
-
Harley, C.B.1
Vaziri, H.2
Counter, C.M.3
-
26
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie ND, Dempster M, Dunlop MG, et al.: Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990, 346: 866-868.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
-
27
-
-
0031041024
-
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease
-
Kojima H, Yokosuka O, Imazeki F, et al.: Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease. Gastroenterology 1997, 112: 493-500.
-
(1997)
Gastroenterology
, vol.112
, pp. 493-500
-
-
Kojima, H.1
Yokosuka, O.2
Imazeki, F.3
-
28
-
-
0026043444
-
In vivo loss of telomeric repeats with age in humans
-
Lindsey J, McGill NI, Lindsey LA, et al.: In vivo loss of telomeric repeats with age in humans. Mutat Res 1991, 256: 45-48.
-
(1991)
Mutat Res
, vol.256
, pp. 45-48
-
-
Lindsey, J.1
McGill, N.I.2
Lindsey, L.A.3
-
29
-
-
10544224540
-
Telomere length in human liver diseases
-
Urabe Y, Nouso K, Higashi T, et al.: Telomere length in human liver diseases. Liver 1996, 16: 293-297.
-
(1996)
Liver
, vol.16
, pp. 293-297
-
-
Urabe, Y.1
Nouso, K.2
Higashi, T.3
-
30
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
Vaziri H, Schachter F, Uchida I, et al.: Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 1993, 52: 661-667.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
-
31
-
-
0031463644
-
Tales of tails: Regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging
-
Weng N-P, Palmer LD, Levine BL, et al.: Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging. Immunol Rev 1997, 160: 43-54.
-
(1997)
Immunol Rev
, vol.160
, pp. 43-54
-
-
Weng, N.-P.1
Palmer, L.D.2
Levine, B.L.3
-
32
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter CM, Avilion AA, LeFeuvre CE, et al.: Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992, 11: 1921-1929.
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
Lefeuvre, C.E.3
-
33
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, et al.: Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266: 2011-2014.
-
(1994)
Science
, vol.266
, pp. 2011-2014
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
-
34
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33: 777-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 777-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
35
-
-
0029872174
-
Telomerase activity in human germline and embryonic tissues and cells
-
Wright WE, Piatyszek MA, Rainey WE, et al.: Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 1996, 18: 173-179.
-
(1996)
Dev Genet
, vol.18
, pp. 173-179
-
-
Wright, W.E.1
Piatyszek, M.A.2
Rainey, W.E.3
-
36
-
-
0030579071
-
Mechanism of telomerase induction during T cell activation
-
Bodnar A, Kim NW, Effros RB, et al.: Mechanism of telomerase induction during T cell activation. Exp Cell Res 1996, 228: 58-64.
-
(1996)
Exp Cell Res
, vol.228
, pp. 58-64
-
-
Bodnar, A.1
Kim, N.W.2
Effros, R.B.3
-
37
-
-
0029066169
-
Telomerase activity in normal and malignant hematopoietic cells
-
Broccoli D, Young JW, de Lange T: Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci U S A 1995, 92: 9082-9086.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9082-9086
-
-
Broccoli, D.1
Young, J.W.2
De Lange, T.3
-
38
-
-
0029940570
-
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
-
Chiu C-P, Dragowska W, Kim NW, et al.: Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 1996, 14: 239-248.
-
(1996)
Stem Cells
, vol.14
, pp. 239-248
-
-
Chiu, C.-P.1
Dragowska, W.2
Kim, N.W.3
-
39
-
-
0029091386
-
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells
-
Hiyama K, Hirai Y, Kyoizumi S, et al.: Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 1995, 155: 3711-3715.
-
(1995)
J Immunol
, vol.155
, pp. 3711-3715
-
-
Hiyama, K.1
Hirai, Y.2
Kyoizumi, S.3
-
40
-
-
0029019717
-
Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas
-
Tahara H, Nakanishi T, Kitamoto M, et al.: Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res 1995, 55: 2734-2736.
-
(1995)
Cancer Res
, vol.55
, pp. 2734-2736
-
-
Tahara, H.1
Nakanishi, T.2
Kitamoto, M.3
-
41
-
-
0030010433
-
Detection of telomerase activity in malignant and nonmalignant skin conditions
-
Taylor RS, Ramirez RD, Ogoshi M, et al.: Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 1996, 106: 759-765.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 759-765
-
-
Taylor, R.S.1
Ramirez, R.D.2
Ogoshi, M.3
-
42
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
Harley CB: Telomere loss: mitotic clock or genetic time bomb? Mut Res 1991, 256: 271-282.
-
(1991)
Mut Res
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
43
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar AG, Ouellette M, Frolkis M, et al.: Extension of life-span by introduction of telomerase into normal human cells. Science 1998, 279: 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
-
44
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn WC, Stewart SA, Brooks MW, et al.: Inhibition of telomerase limits the growth of human cancer cells. Nature Med 1999, 5: 1164-1170.
-
(1999)
Nature Med
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
-
45
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn WC, Counter CM, Lundberg AS, et al.: Creation of human tumour cells with defined genetic elements. Nature 1999, 400: 464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
-
46
-
-
0032567967
-
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
-
Vaziri H, Benchimol S: Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr Biol 1998, 8: 279-282.
-
(1998)
Curr Biol
, vol.8
, pp. 279-282
-
-
Vaziri, H.1
Benchimol, S.2
-
47
-
-
0033568462
-
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
-
Zhang X, Mar V, Harrington L, et al.: Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genet Dev 1999, 13: 2388-2399.
-
(1999)
Genet Dev
, vol.13
, pp. 2388-2399
-
-
Zhang, X.1
Mar, V.2
Harrington, L.3
-
48
-
-
0029040101
-
Developmental and tissue specific regulation of mouse telomerase and telomere length
-
Prowse KR, Greider CW: Developmental and tissue specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci U S A 1995, 92: 4818-4822.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
49
-
-
0025597974
-
Extensive telomere repeat arrays in mouse are hypervariable
-
Starling JA, Maule J, Hastie ND, et al.: Extensive telomere repeat arrays in mouse are hypervariable. Nucleic Acids Res 1990, 18: 6881-6888.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6881-6888
-
-
Starling, J.A.1
Maule, J.2
Hastie, N.D.3
-
50
-
-
0033834247
-
Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
-
Wright WE, Shay JW: Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology. Nature Med 2000, 6: 849-851.
-
(2000)
Nature Med
, vol.6
, pp. 849-851
-
-
Wright, W.E.1
Shay, J.W.2
-
51
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee HW, Hande MP, et al.: Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 1997, 91: 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
-
52
-
-
0033553516
-
P53 Deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L, Artandi SE, Shen Q, et al.: p53 Deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 1999, 97: 527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
-
53
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a 2/3 cancer-prone mouse
-
Greenberg RA, Chin L, Femino A, et al.: Short dysfunctional telomeres impair tumorigenesis in the INK4a 2/3 cancer-prone mouse. Cell 1999, 97: 515-525.
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
-
54
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
Herrera E, Martinez-A C, Blasco MA: Impaired germinal center reaction in mice with short telomeres. EMBO J 2000, 19: 472-481.
-
(2000)
EMBO J
, vol.19
, pp. 472-481
-
-
Herrera, E.1
Martinez-A, C.2
Ma, B.3
-
55
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
Herrera E, Samper E, Martin-Caballero J, Flores, et al.: Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J 1999, 18: 2950-2960.
-
(1999)
EMBO J
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Flores, M.J.3
-
56
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee H-W, Blasco MA, Gottlieb G, et al.: Essential role of mouse telomerase in highly proliferative organs. Nature 1998, 392: 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.-W.1
Blasco, M.A.2
Gottlieb, G.3
-
57
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph KL, Chang S, Lee H-W, et al.: Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 1999, 96: 701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.-W.3
-
58
-
-
0034681457
-
Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery
-
Rudolph KL, Chang S, Millard M, et al.: Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science 2000, 287: 1253-1258.
-
(2000)
Science
, vol.287
, pp. 1253-1258
-
-
Rudolph, K.L.1
Chang, S.2
Millard, M.3
-
59
-
-
0343228751
-
Telomerasedeficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez, E, Samper E, Flores JM, et al.: Telomerasedeficient mice with short telomeres are resistant to skin tumorigenesis. Nature Genet 2000, 26: 1-4.
-
(2000)
Nature Genet
, vol.26
, pp. 1-4
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
-
60
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and development of epithelial cancers in mice
-
Artandi SE, Chang S, Lee S-L, et al.: Telomere dysfunction promotes non-reciprocal translocations and development of epithelial cancers in mice. Nature 2000, 406: 641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.-L.3
-
61
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN: The free radical theory of aging matures. Physiol Rev 1998, 78: 547-581.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
62
-
-
0032439245
-
Mitochonderial free radical production and aging in mammals and birds
-
Barja G: Mitochonderial free radical production and aging in mammals and birds. Ann N Y Acad Sci 1998, 854: 224-238.
-
(1998)
Ann N y Acad Sci
, vol.854
, pp. 224-238
-
-
Barja, G.1
-
63
-
-
0033963704
-
Oxidative stress and gene regulation
-
Allen RG, Tresini M: Oxidative stress and gene regulation. Free Rad Biol Med 2000, 28: 463-499.
-
(2000)
Free Rad Biol Med
, vol.28
, pp. 463-499
-
-
Allen, R.G.1
Tresini, M.2
-
64
-
-
0032718726
-
Redox signals that regulate the vascular response to injury
-
Berk BC: Redox signals that regulate the vascular response to injury. Thromb Haemost 1999, 82: 810-817.
-
(1999)
Thromb Haemost
, vol.82
, pp. 810-817
-
-
Berk, B.C.1
-
65
-
-
0033655446
-
Regulation of glutathione synthesis
-
Lu S: Regulation of glutathione synthesis. Curr Top Cel Regul 2000, 26: 95-116.
-
(2000)
Curr Top Cel Regul
, vol.26
, pp. 95-116
-
-
Lu, S.1
-
67
-
-
0003693103
-
-
London: University of London Press
-
Pearl R: The Rate of Living. London: University of London Press; 1928.
-
(1928)
The Rate of Living
-
-
Pearl, R.1
-
68
-
-
84867595508
-
Metabolic rate and life span
-
Edited by Witler R. Basel, Switzerland: Karger;
-
Sohl RS: Metabolic rate and life span. In Cellular Aging: Concepts and Mechanisms. Edited by Witler R. Basel, Switzerland: Karger; 1976: 25-40.
-
(1976)
Cellular Aging: Concepts and Mechanisms
, pp. 25-40
-
-
Sohl, R.S.1
-
70
-
-
0034677947
-
NAD(P)H oxidase role in cardiovascular biology and disease
-
Griendling KK, Sorescu D, Ushio-Fukai M: NAD(P)H oxidase role in cardiovascular biology and disease. Circ Res 2000, 86: 494-501.
-
(2000)
Circ Res
, vol.86
, pp. 494-501
-
-
Griendling, K.K.1
Sorescu, D.2
Ushio-Fukai, M.3
-
72
-
-
0030988742
-
Biochemistry and pathobiology of radical-mediated protein oxidation
-
Dean RT, Fu S, Stocker R, et al.: Biochemistry and pathobiology of radical-mediated protein oxidation. Biochem J 1997, 324: 1-18.
-
(1997)
Biochem J
, vol.324
, pp. 1-18
-
-
Dean, R.T.1
Fu, S.2
Stocker, R.3
-
73
-
-
0033013980
-
Differential roles of cyclin-dependent kinase inhibitors P21 and P16 in the mechanisms of senescence and differentiation in human fibroblasts
-
Stein GH, Drulinger LF, Soulard A, et al.: Differential roles of cyclin-dependent kinase inhibitors P21 and P16 in the mechanisms of senescence and differentiation in human fibroblasts. Mol Cell Biol 1999, 19: 2109-2117.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2109-2117
-
-
Stein, G.H.1
Drulinger, L.F.2
Soulard, A.3
-
74
-
-
0030761351
-
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translateral activation of p53 protein involving poly (AR-ribose) polymerase
-
Vaziri H, West MD, Alsopp RC, et al.: ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translateral activation of p53 protein involving poly (AR-ribose) polymerase. EMBO J 1997, 16: 6018-6033.
-
(1997)
EMBO J
, vol.16
, pp. 6018-6033
-
-
Vaziri, H.1
West, M.D.2
Alsopp, R.C.3
-
75
-
-
0032054781
-
Accelerated telomere shortening in fibroblasts after extended periods of confluency
-
Sitte N, Saretzki G, von Zglinicki T: Accelerated telomere shortening in fibroblasts after extended periods of confluency. Free Radic Biol Med 1998, 24: 885-893.
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 885-893
-
-
Sitte, N.1
Saretzki, G.2
Von Zglinicki, T.3
-
76
-
-
0033942779
-
Role of oxidative stress in telomere length regulation and replicative senescence
-
von Zglinicki T: Role of oxidative stress in telomere length regulation and replicative senescence. Ann N Y Acad Sci 2000, 908: 99-110.
-
(2000)
Ann N y Acad Sci
, vol.908
, pp. 99-110
-
-
Von Zglinicki, T.1
-
77
-
-
0030723881
-
Oxidative stress in the Dahl hypertensive rat
-
Swei A, Lacy F, DeLano FA, et al.: Oxidative stress in the Dahl hypertensive rat. Hypertension 1997, 30: 1628-1633.
-
(1997)
Hypertension
, vol.30
, pp. 1628-1633
-
-
Swei, A.1
Lacy, F.2
Delano, F.A.3
-
78
-
-
0032516037
-
Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats
-
Suzuki H, DeLano FA, Parks DA, et al.: Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Natl Acad Sci U S A 1998, 95: 4754-4759.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4754-4759
-
-
Suzuki, H.1
Delano, F.A.2
Parks, D.A.3
-
79
-
-
0029055276
-
In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: Hydroethidine microfluorography
-
Suzuki H, Swei A, Zweifach BW, et al.: In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: hydroethidine microfluorography. Hypertension 1995, 25: 1083-1089.
-
(1995)
Hypertension
, vol.25
, pp. 1083-1089
-
-
Suzuki, H.1
Swei, A.2
Zweifach, B.W.3
-
80
-
-
0031749824
-
Role of increased free radical activity in the pathogenesis of uremic hypertension
-
Vaziri ND, Oveisi F, Ding Y: Role of increased free radical activity in the pathogenesis of uremic hypertension. Kidney Int 1998, 53: 1748-1754.
-
(1998)
Kidney Int
, vol.53
, pp. 1748-1754
-
-
Vaziri, N.D.1
Oveisi, F.2
Ding, Y.3
-
81
-
-
0031749824
-
Increased nitgric oxide inactivation by reactive oxygen species in lead-induced hypertension
-
Vaziri ND, Liang K, Ding Y: Increased nitgric oxide inactivation by reactive oxygen species in lead-induced hypertension. Kidney Int 1998, 53: 1748-1754.
-
(1998)
Kidney Int
, vol.53
, pp. 1748-1754
-
-
Vaziri, N.D.1
Liang, K.2
Ding, Y.3
-
82
-
-
0031748655
-
Role of reactive oxygen species in the signaling cascade of cyclosporine A-mediated up-regulation of eNOS in vascular endothelial cells
-
Lopez-Ongil S, Hernandez-Perera O, Navarro-Antolin J, et al.: Role of reactive oxygen species in the signaling cascade of cyclosporine A-mediated up-regulation of eNOS in vascular endothelial cells. Br J Pharmacol 1998, 124: 447-454.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 447-454
-
-
Lopez-Ongil, S.1
Hernandez-Perera, O.2
Navarro-Antolin, J.3
-
83
-
-
0033854560
-
Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats
-
Vaziri ND, Wang XQ, Oveisi F, et al.: Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension 2000, 36: 142-146.
-
(2000)
Hypertension
, vol.36
, pp. 142-146
-
-
Vaziri, N.D.1
Wang, X.Q.2
Oveisi, F.3
-
84
-
-
0031888499
-
Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension
-
Lacy F, O'Connor DT, Schmid-Schonbein GW: Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension. J Hypertens 1998, 16: 291-303.
-
(1998)
J Hypertens
, vol.16
, pp. 291-303
-
-
Lacy, F.1
O'Connor, D.T.2
Schmid-Schonbein, G.W.3
-
85
-
-
0033695425
-
Plasma hydrogen peroxide production in human essential hypertension. Role of heredity, gender, and ethnicity
-
Lacy F, Kailasam MT, O'Connor DT, et al.: Plasma hydrogen peroxide production in human essential hypertension. Role of heredity, gender, and ethnicity. Hypertension 2000, 36: 878-884.
-
(2000)
Hypertension
, vol.36
, pp. 878-884
-
-
Lacy, F.1
Kailasam, M.T.2
O'Connor, D.T.3
-
86
-
-
0030859450
-
Superoxide dismutase, catalase and glutathione peroxidase activities in human blood: Influence of sex, age and cigarette smoking
-
Bolzan AD, Bianchi MS, Bianchi NO: Superoxide dismutase, catalase and glutathione peroxidase activities in human blood: influence of sex, age and cigarette smoking. Clin Biochem 1997, 30: 449-454.
-
(1997)
Clin Biochem
, vol.30
, pp. 449-454
-
-
Bolzan, A.D.1
Bianchi, M.S.2
Bianchi, N.O.3
-
87
-
-
0030044606
-
Estrogens protect against hydrogen peroxide and arachidonic acid induced DNA damage
-
Tang M, Subbiah MT: Estrogens protect against hydrogen peroxide and arachidonic acid induced DNA damage. Biochem Biophys Acta 1996, 1299: 155-159.
-
(1996)
Biochem Biophys Acta
, vol.1299
, pp. 155-159
-
-
Tang, M.1
Subbiah, M.T.2
-
88
-
-
0342275215
-
Novel estrogens and their radical scavenging effects, iron-chelating and total antioxidative activities: 17 alpha-substituted analogs of delta 9 (11)-dehydro-17 beta estradiol
-
Romer W, Oettel M, Menzenbach B, et al.: Novel estrogens and their radical scavenging effects, iron-chelating and total antioxidative activities: 17 alpha-substituted analogs of delta 9 (11)-dehydro-17 beta estradiol. Steroids 1997, 62: 688-694.
-
(1997)
Steroids
, vol.62
, pp. 688-694
-
-
Romer, W.1
Oettel, M.2
Menzenbach, B.3
-
89
-
-
0033816392
-
Telomere attrition of the human abdominal aorta: Relationships with age and atherosclerosis
-
Okuda K, Khan MY, Skurnick J, et al.: Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis. Atherosclerosis 2000, 152: 391-398.
-
(2000)
Atherosclerosis
, vol.152
, pp. 391-398
-
-
Okuda, K.1
Khan, M.Y.2
Skurnick, J.3
-
90
-
-
0034678050
-
Homocysteine accelerates endothelial cell senescence
-
Xu D, Neville R, Finkel T: Homocysteine accelerates endothelial cell senescence. FEBS Lett 2000, 470: 20-24.
-
(2000)
FEBS Lett
, vol.470
, pp. 20-24
-
-
Xu, D.1
Neville, R.2
Finkel, T.3
-
91
-
-
0032886789
-
Pulse pressure: Is this a clinically useful risk factor?
-
O'Rourke M, Frohlich ED: Pulse pressure: is this a clinically useful risk factor? Hypertension 1999, 34: 372-374.
-
(1999)
Hypertension
, vol.34
, pp. 372-374
-
-
O'Rourke, M.1
Frohlich, E.D.2
-
92
-
-
0034181905
-
Clinical Advisory Statement. Importance of systolic blood pressure in older Americans
-
Izzo JL Jr, Levy D, Black HR: Clinical Advisory Statement. Importance of systolic blood pressure in older Americans. Hypertension 2000, 35: 1021-1024.
-
(2000)
Hypertension
, vol.35
, pp. 1021-1024
-
-
Izzo Jr., J.L.1
Levy, D.2
Black, H.R.3
-
93
-
-
0033670492
-
Estrogen replacement reduces age-associated remodeling in rat mesenteric arteries
-
Zhang Y, Stewart KG, Dandge ST: Estrogen replacement reduces age-associated remodeling in rat mesenteric arteries. Hypertension 2000, 36: 970-974.
-
(2000)
Hypertension
, vol.36
, pp. 970-974
-
-
Zhang, Y.1
Stewart, K.G.2
Dandge, S.T.3
-
94
-
-
0033901259
-
Telomere length inversely correlates with pulse pressure and is highly familial
-
Jeanclos E, Schork NJ, Kyvik KO, et al.: Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension 2000, 36: 195-200.
-
(2000)
Hypertension
, vol.36
, pp. 195-200
-
-
Jeanclos, E.1
Schork, N.J.2
Kyvik, K.O.3
-
95
-
-
0035256310
-
Telomere length as an indicator of biological aging: The gender effect and relation with pulse pressure and pulse wave velocity
-
in press
-
Benetos A, Okuda K, Lajemi M, et al.: Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity. Hypertension 2001, in press.
-
(2001)
Hypertension
-
-
Benetos, A.1
Okuda, K.2
Lajemi, M.3
-
96
-
-
0033747604
-
Short telomeres in patients with vascular dementia: An indicator of low antioxidative capacity and possible risk factor?
-
von Zglinicki T, Serra V, Lorenz M, et al.: Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and possible risk factor? Lab Invest 2000, 80: 1739-1747.
-
(2000)
Lab Invest
, vol.80
, pp. 1739-1747
-
-
Von Zglinicki, T.1
Serra, V.2
Lorenz, M.3
-
97
-
-
0027993344
-
Genetic determination of telomere size in humans: A twin study of three age groups
-
Slagboom PE, Droog S, Boomsma DI: Genetic determination of telomere size in humans: a twin study of three age groups. Am J Hum Genet 1994, 55: 876-882.
-
(1994)
Am J Hum Genet
, vol.55
, pp. 876-882
-
-
Slagboom, P.E.1
Droog, S.2
Boomsma, D.I.3
-
98
-
-
0033406452
-
Estrogen activates telomerase
-
Kyo S, Takakura M, Kanaya T, et al.: Estrogen activates telomerase. Cancer Res 1999, 59: 5917-5921.
-
(1999)
Cancer Res
, vol.59
, pp. 5917-5921
-
-
Kyo, S.1
Takakura, M.2
Kanaya, T.3
-
99
-
-
0023007274
-
Suppression of tumor growth by senescence in virally transformed human fibroblasts
-
O'Brien W, Stenman G, Sager R: Suppression of tumor growth by senescence in virally transformed human fibroblasts. Proc Natl Acad Sci U S A 1986, 83: 8659-8663.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 8659-8663
-
-
O'Brien, W.1
Stenman, G.2
Sager, R.3
|