Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells

Cancer Research

Volumn 62, Issue 11, 2002, Pages 3226-3232

  Huang, Jun Jian ^a,b   Bai, Yun Xiu ^a   Han, Su Wen ^a   Lin, Jian ^a   Xu, Bing ^a   Huang, Cui Fen ^a   Lin, Marie C ^b   Kung, Hsiang Fu ^b   Jing, Da Dao ^c   Wong, Benjamin C Y ^c  

^a BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPEPTIDE; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CARBOXY TERMINAL SEQUENCE; CARCINOGENICITY; CHROMOSOME; CONTROLLED STUDY; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; SENESCENCE; TELOMERE; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; CELL DIVISION; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; MICE; MICE, NUDE; PEPTIDE FRAGMENTS; TELOMERASE; TELOMERE; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036606586     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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