-
1
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley, C B , Futcher, A. B., and Greider, C W. Telomeres shorten during ageing of human fibroblasts Nature (Lond ), 345: 458-460, 1990.
-
(1990)
Nature (Lond )
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
2
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie, N. D., Dempster, M., Dunlop, M G , Thompson, A. M., Green, D. K., and Allshire, R. C. Telomere reduction in human colorectal carcinoma and with ageing. Nature (Lond.), 346: 866-868, 1990.
-
(1990)
Nature (Lond.)
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
3
-
-
0025115349
-
Structure and variability of human chromosome ends
-
de Lange, T., Shiue, L., Myers, R , Cox, D. R., Naylor, S. L., Killery, A M , and Varmus, H. E. Structure and variability of human chromosome ends. Mol. Cell. Biol., 10: 518-527, 1990.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 518-527
-
-
De Lange, T.1
Shiue, L.2
Myers, R.3
Cox, D.R.4
Naylor, S.L.5
Killery, A.M.6
Varmus, H.E.7
-
4
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Washington DC
-
Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M D , Ho, P. L., Coviello, G. M., Wright, W. E , Weinrich, S L., and Shay, J. W Specific association of human telomerase activity with immortal cells and cancer. Science (Washington DC), 266: 2011-2014, 1994.
-
(1994)
Science
, vol.266
, pp. 2011-2014
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
5
-
-
0002309826
-
Telomere dynamics and genomic instability in human cancer
-
E. H. Blackburn and C. W. Greider (eds.), Cold Spring Harbor, NY. Cold Spring Harbor Laboratory
-
de Lange, T. Telomere dynamics and genomic instability in human cancer. In: E. H. Blackburn and C. W. Greider (eds.), Telomeres, pp. 265-293. Cold Spring Harbor, NY. Cold Spring Harbor Laboratory, 1995
-
(1995)
Telomeres
, pp. 265-293
-
-
De Lange, T.1
-
6
-
-
0029114679
-
Telomeres and telomerase in human cancer
-
Bacchetti, S., and Counter, C. M. Telomeres and telomerase in human cancer (Review). Int. J. Oncol., 7: 423-432, 1995.
-
(1995)
Int. J. Oncol.
, vol.7
, pp. 423-432
-
-
Bacchetti, S.1
Counter, C.M.2
-
7
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider, C W., and Blackburn, E H. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell, 43: 405-413, 1985.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
8
-
-
0023663881
-
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
-
Greider, C. W., and Blackburn, E. H. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell, 51: 887-898, 1987.
-
(1987)
Cell
, vol.51
, pp. 887-898
-
-
Greider, C.W.1
Blackburn, E.H.2
-
9
-
-
0029872174
-
Telomerase activity in human germline and embryonic tissues and cells
-
in press
-
Wright, W. E., Piatyszek, M. A., Rainey, W. E , Bryd, W., and Shay, J. W. Telomerase activity in human germline and embryonic tissues and cells. Dev Genet., in press, 1996.
-
(1996)
Dev Genet.
-
-
Wright, W.E.1
Piatyszek, M.A.2
Rainey, W.E.3
Bryd, W.4
Shay, J.W.5
-
10
-
-
0001934324
-
Telomeres and aging
-
E. H. Blackburn and C. W. Greider (eds.), Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Harley, C. B. Telomeres and aging. In: E. H. Blackburn and C. W. Greider (eds.), Telomeres, pp. 247-263. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1995.
-
(1995)
Telomeres
, pp. 247-263
-
-
Harley, C.B.1
-
11
-
-
0029991014
-
Telomerase activity in human cancer
-
in press
-
Shay, J W., and Wright, W. E Telomerase activity in human cancer. Curr. Opin. Oncol , in press, 1996.
-
(1996)
Curr. Opin. Oncol
-
-
Shay, J.W.1
Wright, W.E.2
-
12
-
-
0028981143
-
Time telomeres and tumors: Is cellular senescence more than an anti-cancer mechanism?
-
Wright, W E , and Shay, J. W. Time telomeres and tumors: is cellular senescence more than an anti-cancer mechanism? Trends Cell. Biol., 5: 293-297, 1995.
-
(1995)
Trends Cell. Biol.
, vol.5
, pp. 293-297
-
-
Wright, W.E.1
Shay, J.W.2
-
13
-
-
0028673260
-
Telomerase, cell immortality and cancer
-
Harley, C. B., Kim, N. W., Prowse, K. R., Weinrich, S. L., Hirsh, K. S., West, M. D., Bacchetti, S , Hirte, H W., Counter, C. M., Greider, C. W., Wright, W. E , Shay, J. W. Telomerase, cell immortality and cancer. Cold Spring Harbor Symp. Quant. Biol., 59: 307-315, 1994.
-
(1994)
Cold Spring Harbor Symp. Quant. Biol.
, vol.59
, pp. 307-315
-
-
Harley, C.B.1
Kim, N.W.2
Prowse, K.R.3
Weinrich, S.L.4
Hirsh, K.S.5
West, M.D.6
Bacchetti, S.7
Hirte, H.W.8
Counter, C.M.9
Greider, C.W.10
Wright, W.E.11
Shay, J.W.12
-
14
-
-
0029395466
-
Aging and cancer: Are telomeres and telomerase the connection?
-
Shay, J. W. Aging and cancer: are telomeres and telomerase the connection? Mol. Med. Today, 1: 376-382, 1995.
-
(1995)
Mol. Med. Today
, vol.1
, pp. 376-382
-
-
Shay, J.W.1
-
15
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B., and Bacchetti, S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J , 11: 1921-1929, 1992
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
Lefeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
16
-
-
0028198679
-
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transfromed human B lymphocytes
-
Counter, C. M., Botelho, F. M., Wang, P., Harley, C. B., and Bacchetti, S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transfromed human B lymphocytes. J. Virol., 68: 3410-3414, 1994.
-
(1994)
J. Virol.
, vol.68
, pp. 3410-3414
-
-
Counter, C.M.1
Botelho, F.M.2
Wang, P.3
Harley, C.B.4
Bacchetti, S.5
-
17
-
-
0027263711
-
E6 of human papiloma type 16 can overcome the M1 stage of immortalization in human mammary epithelial cells but not in human fibroblasts
-
Shay, J. W., Wright, W. E , Brasiskyte, D., and Van der Hagen, B. A. E6 of human papiloma type 16 can overcome the M1 stage of immortalization in human mammary epithelial cells but not in human fibroblasts. Oncogene, 8, 1407-1413, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 1407-1413
-
-
Shay, J.W.1
Wright, W.E.2
Brasiskyte, D.3
Van Der Hagen, B.A.4
-
18
-
-
0027944347
-
TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
-
Washington DC
-
Singer, M. S., and Gottschling, D E. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science (Washington DC), 266: 404-409, 1994.
-
(1994)
Science
, vol.266
, pp. 404-409
-
-
Singer, M.S.1
Gottschling, D.E.2
-
19
-
-
0029102354
-
Runaway telomere elongation caused by telomerase RNA gene mutations
-
McEachern, M. J., and Blackburn, E K. Runaway telomere elongation caused by telomerase RNA gene mutations. Nature (Lond.), 376: 403-409, 1995.
-
(1995)
Nature (Lond.)
, vol.376
, pp. 403-409
-
-
McEachern, M.J.1
Blackburn, E.K.2
-
20
-
-
0029096515
-
The human telomerase RNA component
-
Washington DC
-
Feng, J., Funk, W., Wang, S., Weinrich, S., Avilion, A., Chiu, C-P., Adams, R , Chang, E., Yu, J., Le, S., West, M , Harley, C B., Andrews, W., Greider, C W., Villeponteau, B The human telomerase RNA component. Science (Washington DC), 269: 1236-1241, 1995
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.2
Wang, S.3
Weinrich, S.4
Avilion, A.5
Chiu, C.-P.6
Adams, R.7
Chang, E.8
Yu, J.9
Le, S.10
West, M.11
Harley, C.B.12
Andrews, W.13
Greider, C.W.14
Villeponteau, B.15
-
21
-
-
0344252789
-
Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)
-
Piatyszek, M. A , Kim, N. W., Weinrich, S. L., Hiyama, K., Hiyama, E., Wright, W. E., and Shay, J. W. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci., 17 1-15, 1995
-
(1995)
Methods Cell Sci.
, vol.17
, pp. 1-15
-
-
Piatyszek, M.A.1
Kim, N.W.2
Weinrich, S.L.3
Hiyama, K.4
Hiyama, E.5
Wright, W.E.6
Shay, J.W.7
-
22
-
-
0004270170
-
-
New York: Wiley and Sons, Inc
-
Ausubel, F. M., Brent, R , Kingston, R., Moore, D., Seidman, J. G., Smith, J A., and Struhl, K. Current Protocols in Molecular Biology. New York: Wiley and Sons, Inc , 1993.
-
(1993)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.3
Moore, D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
23
-
-
0028938262
-
Telomerase activity in normal leukocytes and in hematologic malignancies
-
Counter, C. M., Gupta, J , Harley, C. B., Leber, B., and Bacchetti, S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood, 85 2315-2320, 1995.
-
(1995)
Blood
, vol.85
, pp. 2315-2320
-
-
Counter, C.M.1
Gupta, J.2
Harley, C.B.3
Leber, B.4
Bacchetti, S.5
-
24
-
-
0029066169
-
Telomerase activity in normal and malignant heamatopoietic cells
-
Broccoli, D., Young, J W., and de Lange, T. Telomerase activity in normal and malignant heamatopoietic cells. Proc. Natl. Acad Sci. USA, 92: 9082-9086, 1995
-
(1995)
Proc. Natl. Acad Sci. USA
, vol.92
, pp. 9082-9086
-
-
Broccoli, D.1
Young, J.W.2
De Lange, T.3
-
25
-
-
0029091386
-
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells
-
Hiyama, K., Hirai, Y , Kyoizumi, S , Akiyama, M., Hiyama, E., Piatyszek, M. A., Shay, J., Ishioka, S., and Yamakido, M Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J. Immunol., 155: 3711-3715, 1995.
-
(1995)
J. Immunol.
, vol.155
, pp. 3711-3715
-
-
Hiyama, K.1
Hirai, Y.2
Kyoizumi, S.3
Akiyama, M.4
Hiyama, E.5
Piatyszek, M.A.6
Shay, J.7
Ishioka, S.8
Yamakido, M.9
-
26
-
-
0028958708
-
Telomeres and telomerase in aging and cancer
-
Harley, C. B., and Villeponteau, B. Telomeres and telomerase in aging and cancer. Curr. Opin Genet. Dev , 5: 249-255, 1995.
-
(1995)
Curr. Opin Genet. Dev
, vol.5
, pp. 249-255
-
-
Harley, C.B.1
Villeponteau, B.2
-
27
-
-
0028883950
-
Restoration of the cellular senescence program and repression of telomerase by chromosome 3
-
Ohmura, H., Tahara, H , Suzuki, M., Ide, T., Shimizu, M., Yoshida, M. A., Tahara, E., Shay, J. W., Barrett, J. C , and Oshimura, M Restoration of the cellular senescence program and repression of telomerase by chromosome 3 Jpn. J. Cancer Res., 86: 899-904, 1995.
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 899-904
-
-
Ohmura, H.1
Tahara, H.2
Suzuki, M.3
Ide, T.4
Shimizu, M.5
Yoshida, M.A.6
Tahara, E.7
Shay, J.W.8
Barrett, J.C.9
Oshimura, M.10
-
28
-
-
0025279059
-
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
-
Yu, G-L., Bradley, J. D , Attardi, L. D , and Blackburn, E H In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature (Lond.), 344: 126-132, 1990.
-
(1990)
Nature (Lond.)
, vol.344
, pp. 126-132
-
-
Yu, G.-L.1
Bradley, J.D.2
Attardi, L.D.3
Blackburn, E.H.4
-
29
-
-
0028990123
-
Purification of Tetrahymena telomerase and cloning of the genes for the two protein components of the enzyme
-
Collins, K., Koybayashi, R., and Greider, C W. Purification of Tetrahymena telomerase and cloning of the genes for the two protein components of the enzyme. Cell. 81: 677-686, 1995
-
(1995)
Cell
, vol.81
, pp. 677-686
-
-
Collins, K.1
Koybayashi, R.2
Greider, C.W.3
-
30
-
-
0029162563
-
Telomere elongation in immortal human cells without detectable telomerase activity
-
Bryan, T. R , Englezou, A., Gupta, J , Bacchetti, S., and Reddel, R. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J., 14: 4240-4248, 1995.
-
(1995)
EMBO J.
, vol.14
, pp. 4240-4248
-
-
Bryan, T.R.1
Englezou, A.2
Gupta, J.3
Bacchetti, S.4
Reddel, R.5
-
31
-
-
85088671963
-
Experimental elongation of telomeres in immortal human cells extends the lifespan of immortal x normal cell hybrids
-
in press
-
Wright, W. e., Brasiskyte, D., Piatyszek, M. A., and Shay, J. W. Experimental elongation of telomeres in immortal human cells extends the lifespan of immortal x normal cell hybrids. EMBO J., in press, 1996.
-
(1996)
EMBO J.
-
-
Wright, W.E.1
Brasiskyte, D.2
Piatyszek, M.A.3
Shay, J.W.4
-
32
-
-
0029156035
-
Telomere shortening is associated with cell division in vitro and in vivo
-
Allsopp, R. C., Chang, E., Kashefi-Aazam, M., Rogaev, E. I , Piatyszek, M A., Shay, J., and Harley, C. B. Telomere shortening is associated with cell division in vitro and in vivo Exp. Cell Res., 220: 194-200, 1995.
-
(1995)
Exp. Cell Res.
, vol.220
, pp. 194-200
-
-
Allsopp, R.C.1
Chang, E.2
Kashefi-Aazam, M.3
Rogaev, E.I.4
Piatyszek, M.A.5
Shay, J.6
Harley, C.B.7
-
33
-
-
0028262113
-
Telomerase activity in human ovarian carcinoma
-
Counter, G. M , Hirte, H W , Bacchetti, S , and Harley, C. B. Telomerase activity in human ovarian carcinoma. Proc. Natl Acad Sci. USA, 91: 2900-2904, 1994
-
(1994)
Proc. Natl Acad Sci. USA
, vol.91
, pp. 2900-2904
-
-
Counter, G.M.1
Hirte, H.W.2
Bacchetti, S.3
Harley, C.B.4
-
34
-
-
0030070054
-
Differential regulation of telomerase activity and telomerase RNA during multistage tumorigenesis
-
in press
-
Blasco, M., Rizen, M., Grieder, C. W., and Hanahan, D. Differential regulation of telomerase activity and telomerase RNA during multistage tumorigenesis. Nat. Genet., in press, 1996
-
(1996)
Nat. Genet.
-
-
Blasco, M.1
Rizen, M.2
Grieder, C.W.3
Hanahan, D.4
|