메뉴 건너뛰기




Volumn 17, Issue 8, 1997, Pages 4677-4686

Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; CYTOKINE; GROWTH FACTOR; HORMONE; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TYROSINE;

EID: 0030795313     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.8.4677     Document Type: Article
Times cited : (112)

References (42)
  • 1
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • Akira, S., Y. Nishio, M. Inoue, X.-J. Wang, S. Wei, T. Matsusaka, K. Yoshida, T. Sudo, M. Naruto, and T. Kishimoto. 1994. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77:63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3    Wang, X.-J.4    Wei, S.5    Matsusaka, T.6    Yoshida, K.7    Sudo, T.8    Naruto, M.9    Kishimoto, T.10
  • 2
    • 0030056861 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93(fes), STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes
    • Brizzi, M. F., M. G. Aronica, A. Rosso, G. P. Bagnara, Y. Yarden, and L. Pegoraro. 1996. Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93(fes), STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes. J. Biol. Chem. 271:3562-3567.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3562-3567
    • Brizzi, M.F.1    Aronica, M.G.2    Rosso, A.3    Bagnara, G.P.4    Yarden, Y.5    Pegoraro, L.6
  • 4
    • 0028952414 scopus 로고
    • Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone
    • Campbell, G. S., D. J. Meyer, R. Raz, D. E. Levy, J. Schwartz, and C. Carter-Su. 1995. Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. J. Biol. Chem. 270:3974-3979.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3974-3979
    • Campbell, G.S.1    Meyer, D.J.2    Raz, R.3    Levy, D.E.4    Schwartz, J.5    Carter-Su, C.6
  • 6
    • 0029965272 scopus 로고    scopus 로고
    • Activation of protein kinase A inhibits Interferon induction of the Jak/Stat pathway in U266 cells
    • David, M., E. Petricoin III, and A. C. Larner. 1996. Activation of protein kinase A inhibits Interferon induction of the Jak/Stat pathway in U266 cells. J. Biol. Chem. 271:4585-4588.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4585-4588
    • David, M.1    Petricoin III, E.2    Larner, A.C.3
  • 7
    • 0030022386 scopus 로고    scopus 로고
    • The membranedistal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation
    • Dekoning, J. P., F. Dong, L. Smith, A. M. Schelen, R. Barge, D. C. Vanderplas, L. H. Hoefsloot, B. Lowenberg, and I. P. Touw. 1996. The membranedistal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation. Blood 87:1335-1342.
    • (1996) Blood , vol.87 , pp. 1335-1342
    • Dekoning, J.P.1    Dong, F.2    Smith, L.3    Schelen, A.M.4    Barge, R.5    Vanderplas, D.C.6    Hoefsloot, L.H.7    Lowenberg, B.8    Touw, I.P.9
  • 8
    • 0026723419 scopus 로고
    • A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)
    • Fu, X. Y. 1992. A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s). Cell 70:323-335.
    • (1992) Cell , vol.70 , pp. 323-335
    • Fu, X.Y.1
  • 9
    • 0026686488 scopus 로고
    • The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction
    • Fu, X. Y., C. Schindler, T. Improta, R. Aebersold, and J. E. Darnell, Jr. 1992. The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc. Natl. Acad. Sci. USA 89:7840-7843.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7840-7843
    • Fu, X.Y.1    Schindler, C.2    Improta, T.3    Aebersold, R.4    Darnell Jr., J.E.5
  • 11
    • 0029887373 scopus 로고    scopus 로고
    • Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin-6 signal transducer gp130. Definition of a novel phosphotyrosine motif mediating STAT1 activation
    • Gerhartz, C., B. Heesel, J. Sasse, U. Hemmann, C. Landgraf, J. Schneider-Mergener, F. Horn, P. C. Heinrich, and L. Graeve. 1996. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin-6 signal transducer gp130. Definition of a novel phosphotyrosine motif mediating STAT1 activation. J. Biol. Chem. 271: 12991-12998.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12991-12998
    • Gerhartz, C.1    Heesel, B.2    Sasse, J.3    Hemmann, U.4    Landgraf, C.5    Schneider-Mergener, J.6    Horn, F.7    Heinrich, P.C.8    Graeve, L.9
  • 12
    • 17544381717 scopus 로고    scopus 로고
    • Application of genomic DNA affinity chromatography identifies multiple interferon-alpha-regulated Stat2 complexes
    • Ghislain, J. J., and E. N. Fish. 1996. Application of genomic DNA affinity chromatography identifies multiple interferon-alpha-regulated Stat2 complexes. J. Biol. Chem. 271:12408-12413.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12408-12413
    • Ghislain, J.J.1    Fish, E.N.2
  • 13
    • 0028979707 scopus 로고
    • Stat recruitment by tyrosine-phosphorylated cytokine receptors: An ordered reversible affinity-driven process
    • Greenlund, A. C., M. O. Morales, B. L. Viviano, H. Yan, J. Krolewski, and R. D. Schreiber. 1995. Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. Immunity 2:677-687.
    • (1995) Immunity , vol.2 , pp. 677-687
    • Greenlund, A.C.1    Morales, M.O.2    Viviano, B.L.3    Yan, H.4    Krolewski, J.5    Schreiber, R.D.6
  • 14
    • 0028946158 scopus 로고
    • Contribution of STAT SH2 groups to specific interferon signaling by the JAKSTAT pathway
    • Heim, M. H., I. M. Kerr, G. R. Stark, and J. E. Darnell, Jr. 1995. Contribution of STAT SH2 groups to specific interferon signaling by the JAKSTAT pathway. Science 267:1347-1349.
    • (1995) Science , vol.267 , pp. 1347-1349
    • Heim, M.H.1    Kerr, I.M.2    Stark, G.R.3    Darnell Jr., J.E.4
  • 15
    • 0029991793 scopus 로고    scopus 로고
    • Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin-6 signal transducer gp130. II. Src homology SH2 domains define the specificity of STAT factor activation
    • Hemmann, U., C. Gerhartz, B. Heesel, J. Sasse, G. Kurapkat, J. Grötzinger, A. Wollmer, Z. Zhong, J. E. Darnell Jr., L. Graeve, P. C. Heinrich, and F. Horn. 1996. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin-6 signal transducer gp130. II. Src homology SH2 domains define the specificity of STAT factor activation. J. Biol. Chem. 271:12999-13007.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12999-13007
    • Hemmann, U.1    Gerhartz, C.2    Heesel, B.3    Sasse, J.4    Kurapkat, G.5    Grötzinger, J.6    Wollmer, A.7    Zhong, Z.8    Darnell Jr., J.E.9    Graeve, L.10    Heinrich, P.C.11    Horn, F.12
  • 16
    • 85036488517 scopus 로고    scopus 로고
    • Unpublished observations
    • Hemmann, U., and F. Horn. Unpublished observations.
    • Hemmann, U.1    Horn, F.2
  • 17
    • 0028913109 scopus 로고
    • A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
    • Horvath, C. M., Z. L. Wen, and J. E. Darnell, Jr. 1995. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev. 9:984-994.
    • (1995) Genes Dev. , vol.9 , pp. 984-994
    • Horvath, C.M.1    Wen, Z.L.2    Darnell Jr., J.E.3
  • 20
    • 0028938929 scopus 로고
    • Interleukin-6-induced serine phosphorylation of transcription factor APRF: Evidence for a role in interleukin-6 target gene induction
    • 19a.Lütticken, C., P. Coffer, J. Yuan, C. Schwartz, C. Schindler, W. Kruijer, P. C. Heinrich, and F. Horn. 1995. Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction. FEBS Lett. 360:137-143.
    • (1995) FEBS Lett. , vol.360 , pp. 137-143
    • Lütticken, C.1    Coffer, P.2    Yuan, J.3    Schwartz, C.4    Schindler, C.5    Kruijer, W.6    Heinrich, P.C.7    Horn, F.8
  • 22
    • 0029975904 scopus 로고    scopus 로고
    • STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line
    • Minami, M., M. lnoue, S. Wei, K. Takeda, M. Matsumoto, T. Kishimoto, and S. Akira. 1996. STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line. Proc. Natl. Acad. Sci. USA 93:3963-3966.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3963-3966
    • Minami, M.1    Lnoue, M.2    Wei, S.3    Takeda, K.4    Matsumoto, M.5    Kishimoto, T.6    Akira, S.7
  • 23
    • 0030052617 scopus 로고    scopus 로고
    • Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets
    • Miyakawa, Y., A. Oda, B. J. Druker, H. Miyazaki, M. Handa, H. Ohashi, and Y. Ikeda. 1996. Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets. Blood 87:439-446.
    • (1996) Blood , vol.87 , pp. 439-446
    • Miyakawa, Y.1    Oda, A.2    Druker, B.J.3    Miyazaki, H.4    Handa, M.5    Ohashi, H.6    Ikeda, Y.7
  • 25
    • 0027434082 scopus 로고
    • Complementation of a mutant cell line: Central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway
    • Müller, M., C. Laxton, J. Briscoe, C. Schindler, T. Improta, J. E. Darnell, Jr., G. R. Stark, and I. M. Kerr. 1993. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway. EMBO J. 12:4221-4228.
    • (1993) EMBO J. , vol.12 , pp. 4221-4228
    • Müller, M.1    Laxton, C.2    Briscoe, J.3    Schindler, C.4    Improta, T.5    Darnell Jr., J.E.6    Stark, G.R.7    Kerr, I.M.8
  • 26
    • 0028826595 scopus 로고
    • Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts
    • Novak, U., A. G. Harpur, L. Paradiso, V. Kanagasundaram, A. Jaworowski, A. F. Wilks, and J. A. Hamilton. 1995. Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 86:2948-2956.
    • (1995) Blood , vol.86 , pp. 2948-2956
    • Novak, U.1    Harpur, A.G.2    Paradiso, L.3    Kanagasundaram, V.4    Jaworowski, A.5    Wilks, A.F.6    Hamilton, J.A.7
  • 27
    • 0028085525 scopus 로고
    • Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver
    • Ruff-Jamison, S., Z. Zhong, Z. Wen, K. Chen, J. E. Darnell, Jr., and S. Cohen. 1994. Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver. J. Biol. Chem. 269:21933-21935.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21933-21935
    • Ruff-Jamison, S.1    Zhong, Z.2    Wen, Z.3    Chen, K.4    Darnell Jr., J.E.5    Cohen, S.6
  • 28
    • 0029075875 scopus 로고
    • Cooperative transcriptional activity of Jun and Stat3β, a short form of Stat3
    • Schaefer, T. S., L. K. Sanders, and D. Nathans. 1995. Cooperative transcriptional activity of Jun and Stat3β, a short form of Stat3. Proc. Natl. Acad. Sci. USA 92:9097-9101.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9097-9101
    • Schaefer, T.S.1    Sanders, L.K.2    Nathans, D.3
  • 29
    • 0026725868 scopus 로고
    • Proteins of transcription factor ISGF-3: One gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha
    • Schindler, C., X. Y. Fu, T. Improta, R. Aebersold, and J. E. Darnell, Jr. 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc. Natl. Acad. Sci. USA 89:7836-7839.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7836-7839
    • Schindler, C.1    Fu, X.Y.2    Improta, T.3    Aebersold, R.4    Darnell Jr., J.E.5
  • 30
    • 0029001660 scopus 로고
    • Components of a Stat recognition code: Evidence for two layers of molecular selectivity
    • Schindler, U., P. Wu, M. Rothe, M. Brasseur, and S. L. McKnight. 1995. Components of a Stat recognition code: evidence for two layers of molecular selectivity. Immunity 2:689-697.
    • (1995) Immunity , vol.2 , pp. 689-697
    • Schindler, U.1    Wu, P.2    Rothe, M.3    Brasseur, M.4    McKnight, S.L.5
  • 32
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
    • Shuai, K., C. M. Horvath, L. H. T. Huang, S. A. Qureshi, D. Cowburn, and J. E. Darnell, Jr. 1994. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 76:821-828.
    • (1994) Cell , vol.76 , pp. 821-828
    • Shuai, K.1    Horvath, C.M.2    Huang, L.H.T.3    Qureshi, S.A.4    Cowburn, D.5    Darnell Jr., J.E.6
  • 33
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91-kD-DNA binding protein
    • Shuai, K., C. Schindler, V. R. Prezioso, and J. E. Darnell, Jr. 1992. Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91-kD-DNA binding protein. Science 258:1808-1812.
    • (1992) Science , vol.258 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell Jr., J.E.4
  • 34
    • 0029742102 scopus 로고    scopus 로고
    • Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1
    • 32a.Shuai, K., J. Liao, and M. M. Song. 1996. Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1. Mol. Cell. Biol. 16:4932-4941.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4932-4941
    • Shuai, K.1    Liao, J.2    Song, M.M.3
  • 35
    • 0028931604 scopus 로고
    • Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
    • Stahl, N., T. J. Farruggella, T. G. Boulton, Z. Zhong, J. E. Darnell, Jr., and G. D. Yancopoulos. 1995. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267:1349-1353.
    • (1995) Science , vol.267 , pp. 1349-1353
    • Stahl, N.1    Farruggella, T.J.2    Boulton, T.G.3    Zhong, Z.4    Darnell Jr., J.E.5    Yancopoulos, G.D.6
  • 36
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stöcklin, E., M. Wissler, F. Gouilleux, and B. Groner. 1996. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383:726-728.
    • (1996) Nature , vol.383 , pp. 726-728
    • Stöcklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 37
    • 0025639009 scopus 로고
    • The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
    • Wagner, B. J., T. E. Hayes, C. J. Hoban, and B. H. Cochran. 1990. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 9:4477-4484.
    • (1990) EMBO J. , vol.9 , pp. 4477-4484
    • Wagner, B.J.1    Hayes, T.E.2    Hoban, C.J.3    Cochran, B.H.4
  • 38
    • 0027441586 scopus 로고
    • Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level
    • Wegenka, U. M., J. Buschmann, C. Lütticken, P. C. Heinrich, and F. Horn. 1993. Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level. Mol. Cell. Biol. 13:276-288.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 276-288
    • Wegenka, U.M.1    Buschmann, J.2    Lütticken, C.3    Heinrich, P.C.4    Horn, F.5
  • 39
    • 0028274299 scopus 로고
    • The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family
    • Wegenka, U. M., C. Lütticken, J. Buschmann, J. Yuan, F. Lottspeich, W. Müller-Esterl, C. Schindler, E. Roeb, P. C. Heinrich, and F. Horn. 1994. The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family. Mol. Cell. Biol. 14:3186-3196.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3186-3196
    • Wegenka, U.M.1    Lütticken, C.2    Buschmann, J.3    Yuan, J.4    Lottspeich, F.5    Müller-Esterl, W.6    Schindler, C.7    Roeb, E.8    Heinrich, P.C.9    Horn, F.10
  • 40
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 41
    • 0028211553 scopus 로고
    • The signaling pathways of interleukin-6 and interferon-γ converge by the activation of different transcription factors which bind to common responsive DNA elements
    • Yuan, J., U. M. Wegenka, C. Lütticken, J. Buschmann, T. Decker, C. Schindler, P. C. Heinrich, and F. Horn. 1994. The signaling pathways of interleukin-6 and interferon-γ converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol. Cell. Biol. 14:1657-1668.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1657-1668
    • Yuan, J.1    Wegenka, U.M.2    Lütticken, C.3    Buschmann, J.4    Decker, T.5    Schindler, C.6    Heinrich, P.C.7    Horn, F.8
  • 42
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong, Z., Z. Wen, and J. E. Darnell, Jr. 1994. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.