Regulators of G-protein signalling as new central nervous system drug targets

Nature Reviews Drug Discovery

Volumn 1, Issue 3, 2002, Pages 187-197

  Neubig, Richard R ^a   Siderovski, David P ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; ADENYLATE CYCLASE; CATECHOLAMINE; CORTICOSTERONE; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATE; LIPOPOLYSACCHARIDE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; OPIATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN INHIBITOR; PROTEIN KINASE (CALCIUM,CALMODULIN); RGS PROTEIN; RGS PROTEIN INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CENTRAL NERVOUS SYSTEM AGENTS; GUANINE NUCLEOTIDE BINDING PROTEIN;

ALZHEIMER DISEASE; BIOCHEMISTRY; BRAIN REGION; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; DEPRESSION; DRUG RESEARCH; DRUG TARGETING; EPILEPSY; HUMAN; MOUSE; NONHUMAN; PAIN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; SPASTICITY; TISSUE SPECIFICITY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION;

ANIMALS; CENTRAL NERVOUS SYSTEM AGENTS; GTP-BINDING PROTEINS; HOMEOSTASIS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTORS, CELL SURFACE; RGS PROTEINS; SIGNAL TRANSDUCTION;

EID: 0036490096     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd747     Document Type: Review

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