NMR structure of free RGS4 reveals an induced conformational change upon binding Gα

Biochemistry

Volumn 39, Issue 24, 2000, Pages 7063-7073

  Moy, Franklin J ^a   Chanda, Pranab K ^a   Cockett, Mark I ^a   Edris, Wade ^a   Jones, Philip G ^a   Mason, Kim ^a   Semus, Simon ^a   Powers, Robert ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; GEOMETRY; HYDROGEN BOND; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RGS PROTEINS; SIGNAL TRANSDUCTION;

EID: 0034691314     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992760w     Document Type: Article

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