Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 27145-27151

  Reuther, Gary W ^a,c   Lambert, Que T ^a   Booden, Michelle A ^a   Wennerberg, Krister ^a   Becknell, Brian ^b   Marcucci, Guido ^b   Sondek, John ^a   Caligiuri, Michael A ^b   Der, Channing J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; BIOCHEMISTRY; CHEMICAL ACTIVATION; HUMAN ENGINEERING; MUTAGENESIS; PATIENT TREATMENT;

LEUKEMIA;

PROTEINS;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; LEUKEMIA ASSOCIATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PLECKSTRIN; PROTEIN CDC42; PROTEIN DBL; RAC PROTEIN; RAC1 PROTEIN; RAF PROTEIN; RAF1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERUM RESPONSE FACTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ARHGEF12 PROTEIN, HUMAN; DNA BINDING PROTEIN; NUCLEAR PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CANCER; CELL LINEAGE; CELL STRAIN 3T3; COMPLEX FORMATION; EMBRYO; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; MALIGNANT TRANSFORMATION; MOUSE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; CELL TRANSFORMATION; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALIA;

CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MALE; NUCLEAR PROTEINS; RHOA GTP-BINDING PROTEIN; SERUM RESPONSE FACTOR;

EID: 0035920247     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103565200     Document Type: Article

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