Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity

Journal of Neuroscience

Volumn 18, Issue 18, 1998, Pages 7178-7188

  Ingi, Tatsuya ^a   Krumins, Andrejs M ^b   Chidiac, Peter ^b   Brothers, Greg M ^c   Chung, Stephen ^c   Snow, Bryan E ^c   Barnes, Carol A ^d   Lanahan, Anthony A ^a   Siderovski, David P ^c   Ross, Elliott M ^b   Gilman, Alfred G ^b   Worley, Paul F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c AMGEN INSTITUTE   (Canada)

^d UNIVERSITY OF ARIZONA   (United States)

Author keywords

G protein; GTPase activating proteins; Immediate early genes; MAP kinase; Neuronal plasticity; RGS; Seizure

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; IMMEDIATE EARLY GENE; MALE; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION;

EID: 17344374133     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-18-07178.1998     Document Type: Article

References (15)

1. Agranoff BW (1981) Learning and memory: biochemical approaches. Boston: Little, Brown.
2. Bailey CH, Kaang BK, Chen M, Martin KC, Lim CS, Casadio A, Kandel ER (1997) Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons. Neuron 18:913-924.
3. Barnes CA, Jung MW, McNaughton BL, Korol DL, Andreasson K, Worley PF (1994) LTP saturation and spatial learning disruption: effects of task variables and saturation levels. J Neurosci 14:5793-5806.
4. Berman DM, Gilman AG (1998) Mammalian RGS protein: barbarians at the gate. J Biol Chem 273:1269-1272.
5. Berman DM, Wilkie TM, Gilman AG (1996) GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86:445-452.
6. Bhat RV, Baraban JM (1993) Activation of transcription factor genes in striatum by cocaine: role of both serotonin and dopamine systems. J Pharmacol Exp Ther 267:496-505.
7. Biddlecome GH, Berstein G, Ross EM (1996) Regulation of phospholipase C-betal by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation. J Biol Chem 271:7999-8007.
8. Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF (1997) Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386:284-288.
9. Carlson JH, Bergstrom DA, Walters JR (1986) Neurophysiological evidence that D-1 dopamine receptor blockade attenuates postsynaptic but not autoreceptor-mediated effects of dopamine agonists. Eur J Pharmacol 123:237-251.
10. Chan RK, Otte CA (1982a) Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones. Mol Cell Biol 2:11-20.
11. Chan RK, Otte CA (1982b) Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones. Mol Cell Biol 2:21-29.
12. Chatterjee TK, Eapen AK, Fisher RA (1997) A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C. J Biol Chem 272:15481-15487.
13. Chen CK, Wieland T, Simon MI (1996) RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling. Proc Natl Acad Sci USA 93:12885-12889.
14. Cole AJ, Abu-Shakra S, Saffen DW, Baraban JM, Worley PF (1990) Rapid rise in transcription factor mRNAs in rat brain after electroshock-induced seizures. J Neurochem 55:1920-1927.
15. Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ (1997) Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2: and Src kinase. J Biol Chem 272:19125-19132.