-
1
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG (2001) Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 10:687-692
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
2
-
-
0025716314
-
DNA methylation and epigenetic inheritance
-
Holliday R (1990) DNA methylation and epigenetic inheritance. Philos Trans R Soc Lond B Biol Sci 326:329-338
-
(1990)
Philos Trans R Soc Lond B Biol Sci
, vol.326
, pp. 329-338
-
-
Holliday, R.1
-
3
-
-
0023788488
-
Effect of HpaII and MspI restriction endonucleases on chronic myelogenous leukemia chromosomes. Detection of CpG dinucleotide demethylation in situ
-
Ferrucci L, Mezzanotte R, Vanni R, Stuppia R, Guanciali-Franchi P, Calabrese G, Palka G, Bianchi U, Sumner AT (1988) Effect of HpaII and MspI restriction endonucleases on chronic myelogenous leukemia chromosomes. Detection of CpG dinucleotide demethylation in situ. Cancer Genet Cytogenet 34:251-256
-
(1988)
Cancer Genet Cytogenet
, vol.34
, pp. 251-256
-
-
Ferrucci, L.1
Mezzanotte, R.2
Vanni, R.3
Stuppia, R.4
Guanciali-Franchi, P.5
Calabrese, G.6
Palka, G.7
Bianchi, U.8
Sumner, A.T.9
-
4
-
-
0032103212
-
Altered patterns of DNA methylation on chromosomes from leukemia cell lines: Identification of 5-methylcytosines by indirect immunodetection
-
Bensaada M, Kiefer H, Tachdjian G, Lapierre LM, Cacheux V, Niveleau A, Metezeau P (1998) Altered patterns of DNA methylation on chromosomes from leukemia cell lines: identification of 5-methylcytosines by indirect immunodetection. Cancer Genet Cytogenet 103:101-109
-
(1998)
Cancer Genet Cytogenet
, vol.103
, pp. 101-109
-
-
Bensaada, M.1
Kiefer, H.2
Tachdjian, G.3
Lapierre, L.M.4
Cacheux, V.5
Niveleau, A.6
Metezeau, P.7
-
5
-
-
0026317881
-
High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer
-
El-Deiry WS, Nelkin BD, Celano P, Yen RW, Falco JP, Hamilton SR, Baylin SB (1991) High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer. Proc Natl Acad Sci USA 88: 3470-3474
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3470-3474
-
-
El-Deiry, W.S.1
Nelkin, B.D.2
Celano, P.3
Yen, R.W.4
Falco, J.P.5
Hamilton, S.R.6
Baylin, S.B.7
-
6
-
-
0030009868
-
Mechanisms for the involvement of DNA methylation in colon carcinogenesis
-
Schmutte C, Yang AS, Nguyen TT, Beart RW, Jones PA (1996) Mechanisms for the involvement of DNA methylation in colon carcinogenesis. Cancer Res 56:2375-2381
-
(1996)
Cancer Res
, vol.56
, pp. 2375-2381
-
-
Schmutte, C.1
Yang, A.S.2
Nguyen, T.T.3
Beart, R.W.4
Jones, P.A.5
-
7
-
-
0029812553
-
Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation
-
Lee PJ, Washer LL, Law DJ, Boland CR, Horon IL, Feinberg AP (1996) Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation. Proc Natl Acad Sci USA 93:10366-10370
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10366-10370
-
-
Lee, P.J.1
Washer, L.L.2
Law, D.J.3
Boland, C.R.4
Horon, I.L.5
Feinberg, A.P.6
-
8
-
-
0027198976
-
Increased cytosine DNA-methyltransferase activity during colon cancer progression
-
Issa JP, Vertino PM, Wu JJ, Sazawal S, Celano P, Nelkin BD, Hamilton SR, Baylin SB (1993) Increased cytosine DNA-methyltransferase activity during colon cancer progression. J Natl Cancer Inst 85:1235-1240
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1235-1240
-
-
Issa, J.P.1
Vertino, P.M.2
Wu, J.J.3
Sazawal, S.4
Celano, P.5
Nelkin, B.D.6
Hamilton, S.R.7
Baylin, S.B.8
-
9
-
-
0030006213
-
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer
-
Belinsky SA, Nikula KJ, Baylin SB, Issa JP (1996) Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer. Proc Natl Acad Sci USA 93:4045-4050
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4045-4050
-
-
Belinsky, S.A.1
Nikula, K.J.2
Baylin, S.B.3
Issa, J.P.4
-
11
-
-
0035283201
-
Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
-
Mizuno S, Chijiwa T, Okamura T, Akashi K, Fukumaki Y, Niho Y, Sasaki H (2001) Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 97:1172-1179
-
(2001)
Blood
, vol.97
, pp. 1172-1179
-
-
Mizuno, S.1
Chijiwa, T.2
Okamura, T.3
Akashi, K.4
Fukumaki, Y.5
Niho, Y.6
Sasaki, H.7
-
12
-
-
0015305183
-
The generation time of human leukemic myeloblasts
-
Greenberg ML, Chanana AD, Cronkite EP, Giacomelli G, Schiffer LM, Stryctmans PA, Vincent PC (1972) The generation time of human leukemic myeloblasts. Lab Invest 26:245-252
-
(1972)
Lab Invest
, vol.26
, pp. 245-252
-
-
Greenberg, M.L.1
Chanana, A.D.2
Cronkite, E.P.3
Giacomelli, G.4
Schiffer, L.M.5
Stryctmans, P.A.6
Vincent, P.C.7
-
13
-
-
0010648051
-
Proliferative activity of blast cells in leukemia and myelofibrosis. Morphological differences between proliferating and non-proliferating blast cells
-
Killmann SA (1965) Proliferative activity of blast cells in leukemia and myelofibrosis. Morphological differences between proliferating and non-proliferating blast cells. Acta Med Scand 178:263-280
-
(1965)
Acta Med Scand
, vol.178
, pp. 263-280
-
-
Killmann, S.A.1
-
14
-
-
0027504621
-
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH-3T3 cells
-
Wu JJ, Issa JP, Herman JG, Bassett DE, Nelkin BD, Baylin SB (1993) Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH-3T3 cells. Proc Natl Acad Sci USA 90:8891-8895
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8891-8895
-
-
Wu, J.J.1
Issa, J.P.2
Herman, J.G.3
Bassett, D.E.4
Nelkin, B.D.5
Baylin, S.B.6
-
15
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Edward Jung W, Li E, Weinberg RA, Jaenisch R (1995) Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81:197-205
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
Dickinson, S.L.4
Edward Jung, W.5
Li, E.6
Weinberg, R.A.7
Jaenisch, R.8
-
16
-
-
0029868994
-
Overproduction of DNA cytosine methyltransferases causes methylation and C→T mutations at non-canonical sites
-
Bandaru B, Gopal J, Bhagwat AS (1996) Overproduction of DNA cytosine methyltransferases causes methylation and C→T mutations at non-canonical sites. J Biol Chem 271:7851-7859
-
(1996)
J Biol Chem
, vol.271
, pp. 7851-7859
-
-
Bandaru, B.1
Gopal, J.2
Bhagwat, A.S.3
-
17
-
-
0025145277
-
5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
-
Rideout III WM, Coetzee GA, Olumi AF, Jones PA (1990) 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249:1288-1290
-
(1990)
Science
, vol.249
, pp. 1288-1290
-
-
Rideout W.M. III1
Coetzee, G.A.2
Olumi, A.F.3
Jones, P.A.4
-
18
-
-
0021101229
-
The 5-methylcytosine content of DNA from human tumors
-
Gama-Sosa MA, Slagel VA, Trewyn RW, Oxenhandler R, Kuo KC, Gehrke CW, Ehrlich M (1983) The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res 11:6883-6894
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6883-6894
-
-
Gama-Sosa, M.A.1
Slagel, V.A.2
Trewyn, R.W.3
Oxenhandler, R.4
Kuo, K.C.5
Gehrke, C.W.6
Ehrlich, M.7
-
19
-
-
17144460958
-
Hypomethylation of DNA: A nongenotoxic mechanism involved in tumor promotion
-
Counts JL, Goodman JI (1995) Hypomethylation of DNA: a nongenotoxic mechanism involved in tumor promotion. Toxicol Lett 82/83:663-672
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 663-672
-
-
Counts, J.L.1
Goodman, J.I.2
-
20
-
-
0029824194
-
Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma
-
Cravo M, Pinto R, Fidalgo P, Chaves P, Gloria L, Nobreleitao C, Mira FC (1996) Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma. Gut 39:434-438
-
(1996)
Gut
, vol.39
, pp. 434-438
-
-
Cravo, M.1
Pinto, R.2
Fidalgo, P.3
Chaves, P.4
Gloria, L.5
Nobreleitao, C.6
Mira, F.C.7
-
21
-
-
0026786945
-
Genomic hypomethylation in human chronic lymphocytic leukemia
-
Wahlfors J, Hiltunen H, Heinonen K, Hamalainen E, Alhonen L, Jänne J (1992) Genomic hypomethylation in human chronic lymphocytic leukemia. Blood 80:2074-2080
-
(1992)
Blood
, vol.80
, pp. 2074-2080
-
-
Wahlfors, J.1
Hiltunen, H.2
Heinonen, K.3
Hamalainen, E.4
Alhonen, L.5
Jänne, J.6
-
22
-
-
0027256637
-
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency
-
Christman JK, Sheikhnejad G, Dizik M, Abileah S, Wainfan E (1993) Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency. Carcinogenesis 14:551-557
-
(1993)
Carcinogenesis
, vol.14
, pp. 551-557
-
-
Christman, J.K.1
Sheikhnejad, G.2
Dizik, M.3
Abileah, S.4
Wainfan, E.5
-
23
-
-
0028925741
-
Breaks in genomic DNA and within the p53gene are associated with hypomethylation in livers of folate/methyl-deficient rats
-
Pogribny IP, Basnakian AG, Miller BJ, Lopatina NG, Poirier LA, James SJ (1995) Breaks in genomic DNA and within the p53gene are associated with hypomethylation in livers of folate/methyl-deficient rats. Cancer Res 55:1894-1901
-
(1995)
Cancer Res
, vol.55
, pp. 1894-1901
-
-
Pogribny, I.P.1
Basnakian, A.G.2
Miller, B.J.3
Lopatina, N.G.4
Poirier, L.A.5
James, S.J.6
-
24
-
-
0031149098
-
Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat
-
Pogribny IP, Miller BJ, James SJ (1997) Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat. Cancer Lett 115:31-38
-
(1997)
Cancer Lett
, vol.115
, pp. 31-38
-
-
Pogribny, I.P.1
Miller, B.J.2
James, S.J.3
-
25
-
-
17144441661
-
A microassay for measuring cytosine DNA methyltransferase activity during tumor progression
-
Belinsky SA, Nikula KJ, Baylin SB, Issa JP (1995) A microassay for measuring cytosine DNA methyltransferase activity during tumor progression. Toxicol Lett 82/83:335-340
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 335-340
-
-
Belinsky, S.A.1
Nikula, K.J.2
Baylin, S.B.3
Issa, J.P.4
-
27
-
-
0031656598
-
Hypomethylation in cervical tissue: Is there a correlation with folate status?
-
Fowler BM, Giuliano AR, Piyathilake C, Nour M, Hatch K (1998) Hypomethylation in cervical tissue: is there a correlation with folate status? Cancer Epidemiol Biomarkers Prev 7:901-906
-
(1998)
Cancer Epidemiol Biomarkers Prev
, vol.7
, pp. 901-906
-
-
Fowler, B.M.1
Giuliano, A.R.2
Piyathilake, C.3
Nour, M.4
Hatch, K.5
-
29
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
Walsh CP, Chaillet JR, Bestor TH (1998) Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet 20:116-117
-
(1998)
Nat Genet
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
30
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301:89-92
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
31
-
-
0032468051
-
Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines
-
Nakamura N, Takenaga K (1998) Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines. Clin Exp Metastasis 16:471-479
-
(1998)
Clin Exp Metastasis
, vol.16
, pp. 471-479
-
-
Nakamura, N.1
Takenaga, K.2
-
32
-
-
0032403478
-
Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias
-
Nakayama M, Wada M, Harada T, Nagayama J, Kusaba H, Ohshima K, Kozuru M, Komatsu H, Ueda R, Kuwano M (1998) Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias. Blood 92:4296-4307
-
(1998)
Blood
, vol.92
, pp. 4296-4307
-
-
Nakayama, M.1
Wada, M.2
Harada, T.3
Nagayama, J.4
Kusaba, H.5
Ohshima, K.6
Kozuru, M.7
Komatsu, H.8
Ueda, R.9
Kuwano, M.10
-
33
-
-
0030983076
-
DNA methylation and genetic instability in colorectal cancer cells
-
Lengauer C, Kinzler KW, Vogelstein B (1997) DNA methylation and genetic instability in colorectal cancer cells. Proc Natl Acad Sci USA 94:2545-2550
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2545-2550
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
34
-
-
0025159811
-
Presence of cell lineage-specific hypomethylated sites in the major breakpoint cluster region
-
Litz CE, Goldfarb AN, Strickler JG, Brunning RD (1990) Presence of cell lineage-specific hypomethylated sites in the major breakpoint cluster region. Cancer Res 50:4984-4990
-
(1990)
Cancer Res
, vol.50
, pp. 4984-4990
-
-
Litz, C.E.1
Goldfarb, A.N.2
Strickler, J.G.3
Brunning, R.D.4
-
35
-
-
0028113752
-
Hypomethylated status, but not RAG-1, is required for T-cell receptor-beta-chain gene rearrangement in acute leukemia cells
-
Kawakubo K, Ohyashiki JH, Ohyashiki K, Tauchi T, Kimura N, Nakazawa S, Toyama K (1994) Hypomethylated status, but not RAG-1, is required for T-cell receptor-beta-chain gene rearrangement in acute leukemia cells. Cancer Genet Cytogenet 78:40-45
-
(1994)
Cancer Genet Cytogenet
, vol.78
, pp. 40-45
-
-
Kawakubo, K.1
Ohyashiki, J.H.2
Ohyashiki, K.3
Tauchi, T.4
Kimura, N.5
Nakazawa, S.6
Toyama, K.7
-
36
-
-
0026443770
-
T-cell receptor beta chain gene rearrangement in acute myeloid leukemia always occurs at the allele that contains the undermethylated J beta 1 region
-
Ohyashiki JH, Ohyashiki K, Kawakubo K, Tauchi T, Nakazawa S, Kimura N, Toyama K (1992) T-cell receptor beta chain gene rearrangement in acute myeloid leukemia always occurs at the allele that contains the undermethylated J beta 1 region. Cancer Res 52:6598-6602
-
(1992)
Cancer Res
, vol.52
, pp. 6598-6602
-
-
Ohyashiki, J.H.1
Ohyashiki, K.2
Kawakubo, K.3
Tauchi, T.4
Nakazawa, S.5
Kimura, N.6
Toyama, K.7
-
38
-
-
0030847733
-
Undermethylation of Alu sequences in ICF syndrome: Molecular and in situ analysis
-
Miniou P, Bourchis D, Gomes DM, Jeanpierre M, Viegas-Pequignot E (1997) Undermethylation of Alu sequences in ICF syndrome: molecular and in situ analysis. Cytogenet Cell Genet 77:308-313
-
(1997)
Cytogenet Cell Genet
, vol.77
, pp. 308-313
-
-
Miniou, P.1
Bourchis, D.2
Gomes, D.M.3
Jeanpierre, M.4
Viegas-Pequignot, E.5
-
39
-
-
0035667192
-
DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes
-
Ehrlich M, Buchanan KL, Tsien F, Jiang G, Sun B, Uicker W, Weemaes CM, Smeets D, Sperling K, Belohradsky BH et al. (2001) DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. Hum Mol Genet 10:2917-2931
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2917-2931
-
-
Ehrlich, M.1
Buchanan, K.L.2
Tsien, F.3
Jiang, G.4
Sun, B.5
Uicker, W.6
Weemaes, C.M.7
Smeets, D.8
Sperling, K.9
Belohradsky, B.H.10
-
40
-
-
0028898746
-
Transcriptional silencing of human alu sequences and inhibition of protein binding in the box b regulatory elements by 5′-CG-3′ methylation
-
Kochanek S, Renz D, Doerfler W (1995) Transcriptional silencing of human alu sequences and inhibition of protein binding in the box b regulatory elements by 5′-CG-3′ methylation. FEBS Lett 360:115-120
-
(1995)
FEBS Lett
, vol.360
, pp. 115-120
-
-
Kochanek, S.1
Renz, D.2
Doerfler, W.3
-
42
-
-
0027304429
-
Nucleosome interactions with a human alu element - Transcriptional repression and effects of template methylation
-
Englander EW, Wolffe AP, Howard BH (1993) Nucleosome interactions with a human alu element - transcriptional repression and effects of template methylation. J Biol Chem 268:19565-19573
-
(1993)
J Biol Chem
, vol.268
, pp. 19565-19573
-
-
Englander, E.W.1
Wolffe, A.P.2
Howard, B.H.3
-
43
-
-
0034720284
-
CpG methylation is maintained in human cancer cells lacking DNMT1
-
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG, Kinzler KW, Vogelstein B, Baylin SB, Schuebel KE (2000) CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 404:1003-1007
-
(2000)
Nature
, vol.404
, pp. 1003-1007
-
-
Rhee, I.1
Jair, K.W.2
Yen, R.W.3
Lengauer, C.4
Herman, J.G.5
Kinzler, K.W.6
Vogelstein, B.7
Baylin, S.B.8
Schuebel, K.E.9
-
44
-
-
0033179375
-
Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
-
Melki JR, Vincent PC, Clark SJ (1999) Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 59:3730-3740
-
(1999)
Cancer Res
, vol.59
, pp. 3730-3740
-
-
Melki, J.R.1
Vincent, P.C.2
Clark, S.J.3
-
45
-
-
0035874532
-
Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci
-
Rush LJ, Dai Z, Smiraglia DJ, Gao X, Wright FA, Fruhwald M, Costello JF, Held WA, Yu L, Krahe R et al. (2001) Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci. Blood 97:3226-3233
-
(2001)
Blood
, vol.97
, pp. 3226-3233
-
-
Rush, L.J.1
Dai, Z.2
Smiraglia, D.J.3
Gao, X.4
Wright, F.A.5
Fruhwald, M.6
Costello, J.F.7
Held, W.A.8
Yu, L.9
Krahe, R.10
-
46
-
-
0032578509
-
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
Belinsky SA, Nikula KJ, Palmisano WA, Michels R, Saccomanno G, Gabrielson E, Baylin SB, Herman JG (1998) Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA 95:11891-11896
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikula, K.J.2
Palmisano, W.A.3
Michels, R.4
Saccomanno, G.5
Gabrielson, E.6
Baylin, S.B.7
Herman, J.G.8
-
47
-
-
0030925099
-
Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors
-
Stirzaker C, Millar DS, Paul CL, Warnecke PM, Harrison J, Vincent PC, Frommer M, Clark SJ (1997) Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res 57:2229-2237
-
(1997)
Cancer Res
, vol.57
, pp. 2229-2237
-
-
Stirzaker, C.1
Millar, D.S.2
Paul, C.L.3
Warnecke, P.M.4
Harrison, J.5
Vincent, P.C.6
Frommer, M.7
Clark, S.J.8
-
48
-
-
0033545329
-
Detailed methylation analysis of the glutathione S-transferase Pi (GSTP1) gene in prostate cancer
-
Millar DS, Ow KK, Paul CL, Russell PJ, Molloy PL, Clark SJ (1999) Detailed methylation analysis of the glutathione S-transferase Pi (GSTP1) gene in prostate cancer. Oncogene 18:1313-1324
-
(1999)
Oncogene
, vol.18
, pp. 1313-1324
-
-
Millar, D.S.1
Ow, K.K.2
Paul, C.L.3
Russell, P.J.4
Molloy, P.L.5
Clark, S.J.6
-
49
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC et al. (2000) Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24:132-138
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
-
50
-
-
0031025368
-
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies
-
Herman JG, Civin CI, Issa JP, Collector MI, Sharkis SJ, Baylin SB (1997) Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Res 57:837-841
-
(1997)
Cancer Res
, vol.57
, pp. 837-841
-
-
Herman, J.G.1
Civin, C.I.2
Issa, J.P.3
Collector, M.I.4
Sharkis, S.J.5
Baylin, S.B.6
-
51
-
-
0030063853
-
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms
-
Issa JP, Zehnbauer BA, Civin CI, Collector MI, Sharkis SJ, Davidson NE, Kaufmann SH, Baylin SB (1996) The estrogen receptor CpG island is methylated in most hematopoietic neoplasms. Cancer Res 56:973-977
-
(1996)
Cancer Res
, vol.56
, pp. 973-977
-
-
Issa, J.P.1
Zehnbauer, B.A.2
Civin, C.I.3
Collector, M.I.4
Sharkis, S.J.5
Davidson, N.E.6
Kaufmann, S.H.7
Baylin, S.B.8
-
52
-
-
0025900902
-
Acceleration of chronic myeloid leukemia correlates with calcitonin gene hypermethylation
-
Malinen T, Palotie A, Pakkala S, Peltonen L, Ruutu T, Jansson SE (1991) Acceleration of chronic myeloid leukemia correlates with calcitonin gene hypermethylation. Blood 77:2435-2440
-
(1991)
Blood
, vol.77
, pp. 2435-2440
-
-
Malinen, T.1
Palotie, A.2
Pakkala, S.3
Peltonen, L.4
Ruutu, T.5
Jansson, S.E.6
-
53
-
-
0032949084
-
Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia
-
Li Q, Kopecky KJ, Mohan A, Willman CL, Appelbaum FR, Weick JK, Issa JP (1999) Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia. Clin Cancer Res 5:1077-1084
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1077-1084
-
-
Li, Q.1
Kopecky, K.J.2
Mohan, A.3
Willman, C.L.4
Appelbaum, F.R.5
Weick, J.K.6
Issa, J.P.7
-
56
-
-
0033215453
-
p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing
-
Cameron EE, Baylin SB, Herman JG (1999) p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing. Blood 94:2445-2451
-
(1999)
Blood
, vol.94
, pp. 2445-2451
-
-
Cameron, E.E.1
Baylin, S.B.2
Herman, J.G.3
-
57
-
-
85047695221
-
Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells
-
in press
-
Song JZ, Stirzaker C, Harrison J, Melki JR, Clark SJ (2002) Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells. Oncogene (in press)
-
(2002)
Oncogene
-
-
Song, J.Z.1
Stirzaker, C.2
Harrison, J.3
Melki, J.R.4
Clark, S.J.5
-
58
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, Strouboulis J, Wolffe AP (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19:187-191
-
(1998)
Nat Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
59
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
60
-
-
0032574859
-
Gene silencing. Methylation meets acetylation
-
Bestor TH (1998) Gene silencing. Methylation meets acetylation. Nature 393:311-312
-
(1998)
Nature
, vol.393
, pp. 311-312
-
-
Bestor, T.H.1
-
61
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB (1999) Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21:103-107
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
62
-
-
0034105545
-
DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: Clinical results and possible mechanisms of action
-
Lubbert M (2000) DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action. Curr Top Microbiol Immunol 249:135-164
-
(2000)
Curr Top Microbiol Immunol
, vol.249
, pp. 135-164
-
-
Lubbert, M.1
-
63
-
-
0031001563
-
Mutagenicity of 5-aza-2′-deoxycytidine is mediated by the mammalian DNA methyltransferase
-
Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R (1997) Mutagenicity of 5-aza-2′-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proc Natl Acad Sci USA 94:4681-4685
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4681-4685
-
-
Jackson-Grusby, L.1
Laird, P.W.2
Magge, S.N.3
Moeller, B.J.4
Jaenisch, R.5
-
64
-
-
0027239823
-
Bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
-
Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC (1993) Bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82:1820-1828
-
(1993)
Blood
, vol.82
, pp. 1820-1828
-
-
Hanada, M.1
Delia, D.2
Aiello, A.3
Stadtmauer, E.4
Reed, J.C.5
-
65
-
-
0024339596
-
Analysis of ras gene mutations and methylation state in human leukemias
-
Browett PJ, Norton JD (1989) Analysis of ras gene mutations and methylation state in human leukemias. Oncogene 4:1029-1036
-
(1989)
Oncogene
, vol.4
, pp. 1029-1036
-
-
Browett, P.J.1
Norton, J.D.2
-
66
-
-
0025895882
-
Changes of DNA methylation and chromatin structure in the human myeloperoxidase gene during myeloid differentiation
-
Lubbert M, Miller CW, Koeffler HP (1991) Changes of DNA methylation and chromatin structure in the human myeloperoxidase gene during myeloid differentiation. Blood 78:345-356
-
(1991)
Blood
, vol.78
, pp. 345-356
-
-
Lubbert, M.1
Miller, C.W.2
Koeffler, H.P.3
-
67
-
-
0026800684
-
A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias
-
Lubbert M, Oster W, Ludwig WD, Ganser A, Mertelsmann R, Herrmann F (1992) A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias. Blood 80:2066-2073
-
(1992)
Blood
, vol.80
, pp. 2066-2073
-
-
Lubbert, M.1
Oster, W.2
Ludwig, W.D.3
Ganser, A.4
Mertelsmann, R.5
Herrmann, F.6
-
68
-
-
0033758181
-
Promoter demethylation accompanies reactivation of the HOX11 proto-oncogene in leukemia
-
Watt PM, Kumar R, Kees UR (2000) Promoter demethylation accompanies reactivation of the HOX11 proto-oncogene in leukemia. Genes Chromosomes Cancer 29:371-377
-
(2000)
Genes Chromosomes Cancer
, vol.29
, pp. 371-377
-
-
Watt, P.M.1
Kumar, R.2
Kees, U.R.3
-
69
-
-
0026086464
-
Increased methylation of the c-fms protooncogene in acute myelomonocytic leukemias
-
Felgner J, Kreipe H, Heidorn K, Jaquet K, Zschunke F, Radzun HJ, Parwaresch MR (1991) Increased methylation of the c-fms protooncogene in acute myelomonocytic leukemias. Pathobiology 59:293-298
-
(1991)
Pathobiology
, vol.59
, pp. 293-298
-
-
Felgner, J.1
Kreipe, H.2
Heidorn, K.3
Jaquet, K.4
Zschunke, F.5
Radzun, H.J.6
Parwaresch, M.R.7
-
70
-
-
0028035056
-
Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia
-
Zion M, Ben Yehuda D, Avraham A, Cohen O, Wetzler M, Melloul D, Ben Neriah Y (1994) Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia. Proc Natl Acad Sci USA 91:10722-10726
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10722-10726
-
-
Zion, M.1
Ben Yehuda, D.2
Avraham, A.3
Cohen, O.4
Wetzler, M.5
Melloul, D.6
Ben Neriah, Y.7
-
71
-
-
0025874367
-
Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia
-
Nelkin BD, Przepiorka D, Burke PJ, Thomas ED, Baylin SB (1991) Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia. Blood 77:2431-2434
-
(1991)
Blood
, vol.77
, pp. 2431-2434
-
-
Nelkin, B.D.1
Przepiorka, D.2
Burke, P.J.3
Thomas, E.D.4
Baylin, S.B.5
-
72
-
-
0027302339
-
Development of molecular genetic methods for monitoring myeloid malignancies
-
Palotie A, Syvanen AC (1993) Development of molecular genetic methods for monitoring myeloid malignancies. Scand J Clin Lab Invest Suppl
-
(1993)
Scand J Clin Lab Invest Suppl
-
-
Palotie, A.1
Syvanen, A.C.2
-
73
-
-
0033740401
-
E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia
-
Corn PG, Smith BD, Ruckdeschel ES, Douglas D, Baylin SB, Herman JG (2000) E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia. Clin Cancer Res 6:4243-4248
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4243-4248
-
-
Corn, P.G.1
Smith, B.D.2
Ruckdeschel, E.S.3
Douglas, D.4
Baylin, S.B.5
Herman, J.G.6
-
74
-
-
0030969482
-
HIC1 hypermethylation is a late event in hematopoietic neoplasms
-
Issa JP, Zehnbauer BA, Kaufmann SH, Biel MA, Baylin SB (1997) HIC1 hypermethylation is a late event in hematopoietic neoplasms. Cancer Res 57:1678-1681
-
(1997)
Cancer Res
, vol.57
, pp. 1678-1681
-
-
Issa, J.P.1
Zehnbauer, B.A.2
Kaufmann, S.H.3
Biel, M.A.4
Baylin, S.B.5
-
75
-
-
0033046553
-
Cancer-specific region of hypermethylation identified within the HIC1 putative tumour suppressor gene in acute myeloid leukaemia
-
Melki JR, Vincent PC, Clark SJ (1999) Cancer-specific region of hypermethylation identified within the HIC1 putative tumour suppressor gene in acute myeloid leukaemia. Leukemia 13:877-883
-
(1999)
Leukemia
, vol.13
, pp. 877-883
-
-
Melki, J.R.1
Vincent, P.C.2
Clark, S.J.3
-
76
-
-
0030046322
-
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B
-
Herman JG, Jen J, Merlo A, Baylin SB (1996) Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res 56:722-727
-
(1996)
Cancer Res
, vol.56
, pp. 722-727
-
-
Herman, J.G.1
Jen, J.2
Merlo, A.3
Baylin, S.B.4
-
77
-
-
0034192151
-
Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: Biological implications
-
Nguyen TT, Mohrbacher AF, Tsai YC, Groffen J, Heisterkamp N, Nichols PW, Yu MC, Lubbert M, Jones PA (2000) Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implications. Blood 95:2990-2992
-
(2000)
Blood
, vol.95
, pp. 2990-2992
-
-
Nguyen, T.T.1
Mohrbacher, A.F.2
Tsai, Y.C.3
Groffen, J.4
Heisterkamp, N.5
Nichols, P.W.6
Yu, M.C.7
Lubbert, M.8
Jones, P.A.9
-
78
-
-
0033188280
-
Homozygous deletion and methylation of p16 and p15 gene in acute leukemia
-
Chen W, Zhang W, Zhu J (1999) Homozygous deletion and methylation of p16 and p15 gene in acute leukemia. Zhonghua Xue Ye Xue Za Zhi 20:474-476
-
(1999)
Zhonghua Xue Ye Xue Za Zhi
, vol.20
, pp. 474-476
-
-
Chen, W.1
Zhang, W.2
Zhu, J.3
-
79
-
-
0033991683
-
Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia
-
Guo SX, Taki T, Ohnishi H, Piao HY, Tabuchi K, Bessho F, Hanada R, Yanagisawa M, Hayashi Y (2000) Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia. Leuk Res 24:39-46
-
(2000)
Leuk Res
, vol.24
, pp. 39-46
-
-
Guo, S.X.1
Taki, T.2
Ohnishi, H.3
Piao, H.Y.4
Tabuchi, K.5
Bessho, F.6
Hanada, R.7
Yanagisawa, M.8
Hayashi, Y.9
-
80
-
-
0035028445
-
Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation
-
Liu M, Taketani T, Li R, Takita J, Taki T, Yang HW, Kawaguchi H, Ida K, Matsuo Y, Hayashi Y (2001) Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation. Leuk Res 25:441-447
-
(2001)
Leuk Res
, vol.25
, pp. 441-447
-
-
Liu, M.1
Taketani, T.2
Li, R.3
Takita, J.4
Taki, T.5
Yang, H.W.6
Kawaguchi, H.7
Ida, K.8
Matsuo, Y.9
Hayashi, Y.10
-
81
-
-
0035353188
-
Methylation profiling in acute myeloid leukemia
-
Toyota M, Kopecky KJ, Toyota MO, Jair KW, Willman CL, Issa JP (2001) Methylation profiling in acute myeloid leukemia. Blood 97:2823-2829
-
(2001)
Blood
, vol.97
, pp. 2823-2829
-
-
Toyota, M.1
Kopecky, K.J.2
Toyota, M.O.3
Jair, K.W.4
Willman, C.L.5
Issa, J.P.6
-
82
-
-
0033215506
-
Cloning and characterization of EphA3 (Hek) gene promoter: DNA methylation regulates expression in hematopoietic tumor cells
-
Dottori M, Down M, Huttmann A, Fitzpatrick DR, Boyd AW (1999) Cloning and characterization of EphA3 (Hek) gene promoter: DNA methylation regulates expression in hematopoietic tumor cells. Blood 94:2477-2486
-
(1999)
Blood
, vol.94
, pp. 2477-2486
-
-
Dottori, M.1
Down, M.2
Huttmann, A.3
Fitzpatrick, D.R.4
Boyd, A.W.5
-
83
-
-
0034662782
-
Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2
-
Tatarelli C, Linnenbach A, Mimori K, Croce CM (2000) Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2. Genomics 68:1-12
-
(2000)
Genomics
, vol.68
, pp. 1-12
-
-
Tatarelli, C.1
Linnenbach, A.2
Mimori, K.3
Croce, C.M.4
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