-
3
-
-
0033578170
-
Reducing errors in medicine
-
(1999)
BMJ
, vol.319
, pp. 136-137
-
-
Berwick, D.1
-
9
-
-
0033576261
-
Drug interactions and the statins
-
(1999)
CMAJ
, vol.161
, pp. 1281-1286
-
-
Herman, R.1
-
10
-
-
0033588470
-
Clinical pharmacology of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
-
(1999)
Life Sci
, vol.65
, pp. 1329-1337
-
-
Moghadasian, M.1
-
11
-
-
0031680609
-
Extending therapy options in treating lipid disorders: A clinical review of cerivastatin, a novel HMG-CoA reductase inhibitor
-
(1998)
Drugs
, vol.56
, pp. 25-31
-
-
Stein, E.A.1
-
12
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival study (4S)
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
13
-
-
0032572086
-
Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
-
(1998)
JAMA
, vol.279
, pp. 1615-1622
-
-
Downs, J.R.1
Clearfield, M.2
Weis, S.3
-
14
-
-
0030841001
-
Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS])
-
(1997)
Am J Cardiol
, vol.80
, pp. 278-286
-
-
Herd, A.1
Ballantyne, C.2
Farmer, J.3
-
15
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
-
(1998)
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
19
-
-
0037140177
-
Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholestoral concentrations: The LIPID trial follow-up
-
(2002)
Lancet
, vol.359
, pp. 1379-1387
-
-
Simes, J.1
-
21
-
-
0035904807
-
Statins are the new aspirin, Oxford Researchers say
-
(2001)
BMJ
, vol.323
, pp. 1145
-
-
Kmietowitz, Z.1
-
23
-
-
0344653659
-
Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris. Findings from the Scandinavian Simvastatin Survival Study (4S)
-
(1997)
Circulation
, vol.96
, pp. 4211-4218
-
-
Miettinen, T.1
Pyorala, K.2
Olsson, A.3
-
24
-
-
0034635863
-
Coronary and cardiovascular risk estimation for primary prevention: Validation of a new Sheffield table in the 1995 Scottish health survey population
-
(2000)
BMJ
, vol.320
, pp. 671-676
-
-
Wallis, E.1
Ramsay, L.2
Ilaq, I.3
-
25
-
-
0034635906
-
Updated New Zealand cardiovascular disease risk-benefit prediction guide
-
(2000)
BMJ
, vol.320
, pp. 709
-
-
Jackson, R.1
-
28
-
-
0032884058
-
Evidence for the benefit of early intervention with pravastatin for secondary prevention of cardiovascular events
-
(1999)
Atherosclerosis
, vol.147
, pp. S17-S21
-
-
Arntz, H.-R.1
-
29
-
-
18044399234
-
US spending on prescription drugs rose by 19% in 2000
-
(2001)
BMJ
, vol.322
, pp. 1198
-
-
Charatan, F.1
-
32
-
-
0029942112
-
Cost effectiveness of lowering cholesterol concentration with statins in patients with and without pre-existing coronary heart disease: Life table method applied to health authority population
-
(1996)
BMJ
, vol.312
, pp. 1443-1446
-
-
Pharoah, P.1
Hollingworth, W.2
-
33
-
-
0028200059
-
Comparison of properties of four inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase
-
(1994)
Am J Cardiol
, vol.73
, pp. D3-D11
-
-
Blum, C.1
-
34
-
-
0023697436
-
Efficacy and long term adverse effect pattern of lovastatin
-
(1988)
Am J Cardiol
, vol.62
, pp. J28-J34
-
-
Tobert, J.1
-
36
-
-
18844469085
-
Expanded clinical evaluation of lovastatin (EXCEL) study results. IV. Additional perspectives on the tolerability of lovastatin
-
(1991)
Am J Med
, vol.91
, pp. S25-S30
-
-
Dujovne, C.1
Chremos, A.2
Pool, J.3
-
37
-
-
0030947754
-
Atorvastatin: A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias
-
(1997)
Drugs
, vol.53
, pp. 828-847
-
-
Lea, A.1
McTavish, D.2
-
40
-
-
18044404125
-
Bayer decides to withdraw cholesterol lowering drug
-
(2001)
BMJ
, vol.323
, pp. 359
-
-
Charatan, F.1
-
41
-
-
0023876839
-
HMG-CoA reductase inhibitors for the treatment of hypercholesterolaemia
-
(1988)
N Engl J Med
, vol.319
, pp. 24-33
-
-
Grundy, S.1
-
44
-
-
0031690802
-
Biochemical and clinical consequences of inhibiting coenzyme Q10 biosynthesis by lipid lowering HMG-CoA reductase inhibitors (statins): A critical overview
-
(1998)
Adv Ther
, vol.15
, pp. 218-228
-
-
Bliznakov, E.1
Wilkins, D.2
-
46
-
-
0027243348
-
Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
-
(1993)
JAMA
, vol.269
, pp. 3015-3123
-
-
-
60
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
-
(1999)
J Biol Chem
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
Zhu, Y.2
Wang, Z.3
-
64
-
-
0031034647
-
Pravastatin: A reappraisal of its pharmacological properties and clinical effectiveness in the management of coronary heart disease
-
(1997)
Drugs
, vol.53
, pp. 299-336
-
-
Haria, M.1
McTavish, D.2
-
65
-
-
0022485201
-
CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: Tissue-selective inhibition of sterol synthesis and hypolipidaemic effects on various animal species
-
(1986)
Biochim Biophys Acta
, vol.877
, pp. 50-60
-
-
Tsujita, Y.1
Kuroda, M.2
Shimada, Y.3
-
69
-
-
0025077819
-
Simvastatin: A review of its pharmacological properties and potential in hypercholesterolaemia
-
(1990)
Drugs
, vol.40
, pp. 583-607
-
-
Todd, P.1
Goa, K.2
-
74
-
-
0031658907
-
Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions
-
(1998)
Drugs
, vol.56
, pp. 15-23
-
-
Muck, W.1
-
85
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glyco-protein: Implications for drug delivery and activity in cancer chemotherapy
-
(1995)
Mol Carcinog
, vol.13
, pp. 129-134
-
-
Wacher, V.1
Wu, C.2
Benet, L.3
-
97
-
-
0028334550
-
Clinical implications of the biopharmaceutical properties of fluvastatin
-
(1994)
Am J Cardiol
, vol.73
, pp. D12-D17
-
-
Deslypere, J.1
-
100
-
-
0029947184
-
Fluvastatin. A review of its pharmacology and use in the management of hypercholesterolaemia
-
(1996)
Drugs
, vol.51
, pp. 433-459
-
-
Plosker, G.1
Wagstaff, A.2
-
113
-
-
0029126528
-
Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole
-
(1995)
N Engl J Med
, vol.333
, pp. 664-665
-
-
Lees, R.1
Lees, A.2
-
119
-
-
0032702855
-
Differential metabolism of statins: Importance of drug-drug interactions
-
(1999)
Eur Heart J
, vol.1
, pp. 7-12
-
-
Horsmans, Y.1
-
120
-
-
0034726386
-
Long-term safety of hepatic hydroxymethyl glutaryl coenzyme A reductase inhibitors - The role of metabolism: Monograph for physicians
-
(2000)
Arch Intern Med
, vol.160
, pp. 2273-2280
-
-
Bottorff, M.1
Hansten, P.2
-
126
-
-
0025095336
-
Biotransformation of lovastatin. III. Effect of cimetidine and famotidine on in-vitro metabolism of lovastatin by rat and human liver microsomes
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 67-73
-
-
Vyas, K.1
Kari, P.2
Wang, R.3
-
127
-
-
0025944905
-
Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
-
(1991)
Arch Biochem Biophys
, vol.290
, pp. 355-361
-
-
Wang, R.1
Kari, P.2
Lu, A.3
-
130
-
-
0023860312
-
Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation
-
(1988)
N Engl J Med
, vol.318
, pp. 48
-
-
Tobert, J.1
-
137
-
-
16044365226
-
Coadministration of itraconazole with hypolipidaemic agents may induce rhabdomyolysis in healthy individuals
-
(1996)
Arch Dermatol
, vol.132
, pp. 1254
-
-
Horn, M.1
-
144
-
-
0033009311
-
Effect of orlistat, a novel anti-obesity agent, on the pharmacokinetics and pharmacodynamics of pravastatin in patients with mild hypercholesterolaemia
-
(1999)
Clin Drug Invest
, vol.17
, pp. 217-233
-
-
Oo, C.1
Akbari, B.2
Lee, S.3
-
147
-
-
0027377733
-
Plasma concentration profiles of simvastatin 3-hydroxy-3 methylglutaryl-co-enzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin
-
(1993)
Nephron
, vol.65
, pp. 410-413
-
-
Arnadottir, M.1
Eriksson, L.2
Thysell, H.3
-
167
-
-
0035949327
-
Bayer faces potential fine over cholesterol lowering drug
-
(2001)
BMJ
, vol.323
, pp. 415a
-
-
Tuffs, A.1
-
181
-
-
0009629284
-
Bilateral subdural haematoma caused by simvastatin during warfarin treatment
-
(1997)
Acta Neurol Scand
, vol.96
, pp. 339
-
-
Rise, I.1
-
187
-
-
0032873946
-
Lack of mutual pharmacokinetic interaction between cerivastatin, a new HMG-CoA reductase inhibitor, and digoxin in healthy normocholesterolaemic volunteers
-
(1999)
Clin Ther
, vol.21
, pp. 1563-1575
-
-
Weber, P.1
Lettieri, J.2
Kaiser, L.3
-
193
-
-
0033592123
-
Polymorphism in high density lipoprotein paraoxonase gene and risk of acute myocardial infarction in men: Prospective nested case-control study
-
(1999)
BMJ
, vol.319
, pp. 487-489
-
-
Salonen, J.1
Malin, R.2
Tuomainen, T.-P.3
-
195
-
-
0029050796
-
Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: The Regression Growth Evaluation Statin study (REGRESS)
-
(1995)
Circulation
, vol.91
, pp. 2528-2540
-
-
Jukema, J.1
Bruschke, A.2
Van Boven, A.3
-
196
-
-
0029154360
-
The influence of pretreatment low density lipoprotein cholesterol concentrations on the effect of hypercholesterolaemic therapy on coronary atherosclerosis in angiographic trials
-
(1995)
Am J Cardiol
, vol.76
, pp. C78-C85
-
-
Sacks, F.1
Gibson, C.2
Rosner, B.3
-
199
-
-
0028283817
-
Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolaemia
-
(1994)
Circulation
, vol.85
, pp. 2419-2524
-
-
Egashira, K.1
Hirooka, Y.2
Kai, H.3
-
201
-
-
0028945643
-
Effects of pravastatin on cardiovascular reactivity to norepinephrine and angiotensin II in patients with hypercholesterolaemia and systemic hypertension
-
(1995)
Am J Cardiol
, vol.75
, pp. 582-586
-
-
Straznicky, N.1
Howes, L.2
Lam, W.3
-
206
-
-
0028866519
-
Hypercholesterolaemia and coronary disease: Correction of the increased thrombogenic potential with cholesterol reduction
-
(1995)
Circulation
, vol.92
, pp. 3172-3177
-
-
Lacoste, L.1
Lam, L.2
Hung, J.3
-
217
-
-
0035814598
-
The renaissance of C reactive protein: It may be a marker not only of acute illness but also of future cardiovascular disease
-
(2001)
BMJ
, vol.322
, pp. 4-5
-
-
Pepys, M.B.1
-
221
-
-
0032865010
-
Mechanisms modifying atherosclerotic disease-from lipids to vascular biology
-
(1999)
Atherosclerosis
, vol.147
, pp. S3-S10
-
-
Weissberg, P.1
-
223
-
-
0023232216
-
Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidaemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
(1987)
N Engl J Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.1
Elo, O.2
Haapa, K.3
-
231
-
-
38249020773
-
The hypolipidaemic effects of lovastatin and clofibrate alone and in combination in patients with type III hyperlipoproteinemia
-
(2001)
Metabolism
, vol.1990
, pp. 403-409
-
-
Illingworth, D.R.1
O'Malley, K.2
-
235
-
-
0033900967
-
A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy - A case report
-
(2000)
Angiology
, vol.51
, pp. 695-697
-
-
Ozdemir, O.1
Boran, M.2
Gokce, V.3
-
240
-
-
0028343111
-
Fluvastatin with and without niacin for hypercholesterolaemia
-
(1994)
Am J Cardiol
, vol.74
, pp. 149-154
-
-
Jacobson, T.1
-
247
-
-
0023929374
-
Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients
-
(1988)
JAMA
, vol.260
, pp. 239-241
-
-
Corpier, C.1
Jones, P.2
Suki, W.3
-
248
-
-
0029008233
-
A preliminary report of the safety and efficacy of fluvastatin for hypercholesterolaemia in renal transplant patients receiving cyclosporine
-
(1995)
Am J Cardiol
, vol.76
, pp. A107-A109
-
-
Goldberg, R.1
Roth, D.2
|