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Volumn 54, Issue 11, 1999, Pages 851-855

Effect of itraconazole on cerivastatin pharmacokinetics

Author keywords

Cerivastatin; Interaction; Itraconazole

Indexed keywords

ANTIFUNGAL AGENT; CERIVASTATIN; CYPROTERONE ACETATE; DESOGESTREL; ETHINYLESTRADIOL; GESTODENE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ITRACONAZOLE; NORGESTIMATE; ORAL CONTRACEPTIVE AGENT; PLACEBO;

EID: 0032948727     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050566     Document Type: Article
Times cited : (53)

References (22)
  • 1
    • 0030914257 scopus 로고    scopus 로고
    • Cerivastatin, a new potent synthetic HMG-CoA reductase inhibitor: Effect of 0.2 mg daily in subjects with primary hypercholesterolemia
    • 1. Stein E, Sprecher D, Allenby KS, Tosiello RL (1997) Cerivastatin, a new potent synthetic HMG-CoA reductase inhibitor: Effect of 0.2 mg daily in subjects with primary hypercholesterolemia. J Cardiovasc Pharmacol 2: 7-16
    • (1997) J Cardiovasc Pharmacol , vol.2 , pp. 7-16
    • Stein, E.1    Sprecher, D.2    Allenby, K.S.3    Tosiello, R.L.4
  • 3
    • 0030893455 scopus 로고    scopus 로고
    • Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved
    • 3. Boberg M, Angerbauer R, Fey P, Kanhai WK, Karl W, Kern A, Ploschke J, Radtke M (1997) Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved. Drug Metab Dispos 25: 321-331
    • (1997) Drug Metab Dispos , vol.25 , pp. 321-331
    • Boberg, M.1    Angerbauer, R.2    Fey, P.3    Kanhai, W.K.4    Karl, W.5    Kern, A.6    Ploschke, J.7    Radtke, M.8
  • 4
    • 0002518012 scopus 로고    scopus 로고
    • Cerivastatin: High enzyme affinity and active metabolites contribute to its high pharmacological activity
    • 4. Bischoff H, Angerbauer R, Boberg M, Schmidt D (1997) Cerivastatin: High enzyme affinity and active metabolites contribute to its high pharmacological activity. Atherosclerosis 130 [Suppl]: S25
    • (1997) Atherosclerosis , vol.130 , Issue.SUPPL.
    • Bischoff, H.1    Angerbauer, R.2    Boberg, M.3    Schmidt, D.4
  • 5
    • 0027331597 scopus 로고
    • Pharmacokinetics of reversible metabolic systems
    • 5. Cheng H, Jusko WJ (1993) Pharmacokinetics of reversible metabolic systems. Biopharm Drug Dispos 14: 721-766
    • (1993) Biopharm Drug Dispos , vol.14 , pp. 721-766
    • Cheng, H.1    Jusko, W.J.2
  • 6
    • 0031892901 scopus 로고    scopus 로고
    • Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole
    • 6. Neuvonen PJ, Kantola T, Kivistö KT (1998) Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 63: 332-341
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 332-341
    • Neuvonen, P.J.1    Kantola, T.2    Kivistö, K.T.3
  • 7
    • 0029758869 scopus 로고    scopus 로고
    • Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
    • 7. Neuvonen PJ, Jalava K-M (1996) Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 60: 54-61
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 54-61
    • Neuvonen, P.J.1    Jalava, K.-M.2
  • 8
    • 0029126528 scopus 로고
    • Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole
    • 8. Lees RS, Lees AM (1995) Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole. N Engl J Med 333: 664-665
    • (1995) N Engl J Med , vol.333 , pp. 664-665
    • Lees, R.S.1    Lees, A.M.2
  • 9
    • 16044365226 scopus 로고    scopus 로고
    • Coadministration of itraconazole with hypolipidemic agents may induce rhabdomyolysis in healthy individuals
    • 9. Horn M (1996) Coadministration of itraconazole with hypolipidemic agents may induce rhabdomyolysis in healthy individuals. Arch Dermatol 132: 1254
    • (1996) Arch Dermatol , vol.132 , pp. 1254
    • Horn, M.1
  • 11
    • 0000979585 scopus 로고
    • A semi-automated, radioenzymatic assay for pravastatin and lovastatin in human serum
    • 11. Manning JA, Swanson BN, Emaus NA, Fry J (1989) A semi-automated, radioenzymatic assay for pravastatin and lovastatin in human serum. Pharm Res 6: S237
    • (1989) Pharm Res , vol.6
    • Manning, J.A.1    Swanson, B.N.2    Emaus, N.A.3    Fry, J.4
  • 13
    • 0025049990 scopus 로고
    • Determination of itraconazole in serum with high-performance liquid chromatography and fluorescence detection
    • 13. Allenmark S, Edebo A, Lindgren K (1990) Determination of itraconazole in serum with high-performance liquid chromatography and fluorescence detection. J Chromatogr 532: 203-206
    • (1990) J Chromatogr , vol.532 , pp. 203-206
    • Allenmark, S.1    Edebo, A.2    Lindgren, K.3
  • 14
    • 0025944905 scopus 로고
    • Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
    • 14. Wang RW, Kari PH, Lu AYH, Thomas PE, Guengerich FP, Vyas KP (1991) Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes. Arch Biochem Biophys 290: 355-361
    • (1991) Arch Biochem Biophys , vol.290 , pp. 355-361
    • Wang, R.W.1    Kari, P.H.2    Lu, A.Y.H.3    Thomas, P.E.4    Guengerich, F.P.5    Vyas, K.P.6
  • 16
    • 0030947754 scopus 로고    scopus 로고
    • Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias
    • 16. Lea AP, McTavish D (1997) Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs 53: 828-847
    • (1997) Drugs , vol.53 , pp. 828-847
    • Lea, A.P.1    McTavish, D.2
  • 17
    • 0031847115 scopus 로고    scopus 로고
    • Effect of itraconazole on the pharmacokinetics of atorvastatin
    • 17. Kantola T, Kivistö KT, Neuvonen PJ (1998) Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 64: 58-65
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 58-65
    • Kantola, T.1    Kivistö, K.T.2    Neuvonen, P.J.3
  • 18
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • 18. Bertz RJ, Granneman GR (1997) Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 32: 210-258
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 20
    • 0031034647 scopus 로고    scopus 로고
    • Pravastatin. A reappraisal of its pharmacological properties and clinical effectiveness in the management of coronary heart disease
    • 20. Haria M, McTavish D (1997) Pravastatin. A reappraisal of its pharmacological properties and clinical effectiveness in the management of coronary heart disease. Drugs 53: 299-336
    • (1997) Drugs , vol.53 , pp. 299-336
    • Haria, M.1    McTavish, D.2
  • 21
    • 0031803373 scopus 로고    scopus 로고
    • Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin
    • 21. Kivistö KT, Kantola T, Neuvonen PJ (1998) Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin. Br J Clin Pharmacol 46: 49-53
    • (1998) Br J Clin Pharmacol , vol.46 , pp. 49-53
    • Kivistö, K.T.1    Kantola, T.2    Neuvonen, P.J.3
  • 22
    • 0031969657 scopus 로고    scopus 로고
    • Influence of erythromycin pre-and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin
    • 22. Mück W, Ochmann K, Rohde G, Unger S, Kuhlmann J (1998) Influence of erythromycin pre-and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin. Eur J Clin Pharmacol 53: 469-473
    • (1998) Eur J Clin Pharmacol , vol.53 , pp. 469-473
    • Mück, W.1    Ochmann, K.2    Rohde, G.3    Unger, S.4    Kuhlmann, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.