메뉴 건너뛰기




Volumn 46, Issue 1, 1998, Pages 49-53

Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin

Author keywords

Fluvastatin; Interaction; Itraconazole; Lovastatin; Pharmacokinetics

Indexed keywords

FLUINDOSTATIN; ITRACONAZOLE; MEVINOLIN;

EID: 0031803373     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.00034.x     Document Type: Article
Times cited : (168)

References (21)
  • 1
    • 0024513882 scopus 로고
    • The physiological disposition of lovastatin
    • Duggan DE, Chen IW, Bayne WF, et al. The physiological disposition of lovastatin. Drug Metab Dispos 1989; 17: 166-173.
    • (1989) Drug Metab Dispos , vol.17 , pp. 166-173
    • Duggan, D.E.1    Chen, I.W.2    Bayne, W.F.3
  • 2
    • 0025944905 scopus 로고
    • Biotransformation of lovastatin. IV. Identification of cytochrome P450, 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
    • Wang RW, Kan PH, Lu AYH, Thomas PE, Guengerich FP, Vyas KP. Biotransformation of lovastatin. IV. Identification of cytochrome P450, 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes. Arch Biochem Biophys 1991; 290: 355-361.
    • (1991) Arch Biochem Biophys , vol.290 , pp. 355-361
    • Wang, R.W.1    Kan, P.H.2    Lu, A.Y.H.3    Thomas, P.E.4    Guengerich, F.P.5    Vyas, K.P.6
  • 3
    • 0008551902 scopus 로고
    • Selective in vitro P450 inhibition profile by fluvastatin indicates its potential in vivo drug interactions
    • Transon C, Leemann T, Dayer P. Selective in vitro P450 inhibition profile by fluvastatin indicates its potential in vivo drug interactions. Clin Pharmacol Ther 1993; 53: 188.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 188
    • Transon, C.1    Leemann, T.2    Dayer, P.3
  • 4
    • 0028846142 scopus 로고
    • In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±) -fluvastatin
    • Transon C, Leemann T, Vogt N, Dayer P. In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±) -fluvastatin. Clin Pharmacol Ther 1995; 58: 412-417.
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 412-417
    • Transon, C.1    Leemann, T.2    Vogt, N.3    Dayer, P.4
  • 5
    • 0023839115 scopus 로고
    • Myolysis and acute renal failure in a heart-transplant patient receiving lovastatin
    • Norman DJ, Illingworth DR, Munson J, Hosenpud J. Myolysis and acute renal failure in a heart-transplant patient receiving lovastatin. N Engl J Med 1988; 318: 46-47.
    • (1988) N Engl J Med , vol.318 , pp. 46-47
    • Norman, D.J.1    Illingworth, D.R.2    Munson, J.3    Hosenpud, J.4
  • 6
    • 0023697436 scopus 로고
    • Efficacy and long-term adverse effect pattern of lovastatin
    • Tobert JA. Efficacy and long-term adverse effect pattern of lovastatin. Am J Cardiol 1988; 62: 28J-34J.
    • (1988) Am J Cardiol , vol.62
    • Tobert, J.A.1
  • 7
    • 0029126528 scopus 로고
    • Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole
    • Lees RS, Lees AM. Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole. N Engl J Med 1995; 333: 664-665.
    • (1995) N Engl J Med , vol.333 , pp. 664-665
    • Lees, R.S.1    Lees, A.M.2
  • 8
    • 0029015986 scopus 로고
    • More on lovastatin
    • Marinella MA. More on lovastatin. West J Med 1995; 162: 176-177.
    • (1995) West J Med , vol.162 , pp. 176-177
    • Marinella, M.A.1
  • 9
    • 0029758869 scopus 로고    scopus 로고
    • Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
    • Neuvonen PJ, Jalava K-M. Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1996; 60: 54-61.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 54-61
    • Neuvonen, P.J.1    Jalava, K.-M.2
  • 10
    • 0022859501 scopus 로고
    • Determination of mevinolin and mevinolinic acid in plasma and bile by reversed-phase high-performance liquid chromatography
    • Stubbs RJ, Schwanz M, Bayne WF. Determination of mevinolin and mevinolinic acid in plasma and bile by reversed-phase high-performance liquid chromatography. J Chromatogr 1986; 383: 438-443.
    • (1986) J Chromatogr , vol.383 , pp. 438-443
    • Stubbs, R.J.1    Schwanz, M.2    Bayne, W.F.3
  • 11
    • 0030943908 scopus 로고    scopus 로고
    • Liquid chromatographic determination of fluvastatin and its enantiomers in blood plasma by automated solid-phase extraction
    • Toreson H, Eriksson B-M. Liquid chromatographic determination of fluvastatin and its enantiomers in blood plasma by automated solid-phase extraction. Chromatographia 1997; 45: 29-34.
    • (1997) Chromatographia , vol.45 , pp. 29-34
    • Toreson, H.1    Eriksson, B.-M.2
  • 12
    • 0025049990 scopus 로고
    • Determination of itraconazole in serum with high-performance liquid chromatography and fluorescence detection
    • Allenmark S, Edebo A, Lindgren K. Determination of itraconazole in serum with high-performance liquid chromatography and fluorescence detection. J Chromatogr 1990; 532: 203-206.
    • (1990) J Chromatogr , vol.532 , pp. 203-206
    • Allenmark, S.1    Edebo, A.2    Lindgren, K.3
  • 13
    • 0030953045 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors
    • Lennernäs H, Fager G. Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Clin Pharmacokinet 1997; 32: 403-425.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 403-425
    • Lennernäs, H.1    Fager, G.2
  • 14
    • 0030463459 scopus 로고    scopus 로고
    • Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine
    • Goldberg R, Roth D. Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine. Transplantation 1996; 62: 1559-1564.
    • (1996) Transplantation , vol.62 , pp. 1559-1564
    • Goldberg, R.1    Roth, D.2
  • 15
    • 0029582977 scopus 로고
    • The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interactions
    • Kivistö KT, Kroemer HK, Eichelbaum M. The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions. Br J Clin Pharmacol 1995; 40: 523-530.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 523-530
    • Kivistö, K.T.1    Kroemer, H.K.2    Eichelbaum, M.3
  • 16
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ, Granneman GR. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 1997; 32: 210-258.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 17
    • 0029040951 scopus 로고
    • Rhabdomyolysis in patients treated with simvastatin and cyclosporin: Role of the hepatic cytochrome P450 enzyme system activity
    • Meier C, Stey C, Brack T, Maggiorini M, Risti B, Krahenbuhl S. Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of the hepatic cytochrome P450 enzyme system activity. Schweiz Med Wochenschr 1995; 125: 1342-1346.
    • (1995) Schweiz Med Wochenschr , vol.125 , pp. 1342-1346
    • Meier, C.1    Stey, C.2    Brack, T.3    Maggiorini, M.4    Risti, B.5    Krahenbuhl, S.6
  • 18
    • 16044365226 scopus 로고    scopus 로고
    • Coadimnistration of itraconazole with hypolipidemic agents may induce rhabdomyolysis in healthy individuals
    • Horn M. Coadimnistration of itraconazole with hypolipidemic agents may induce rhabdomyolysis in healthy individuals. Arch Dermatol 1996; 132: 1254.
    • (1996) Arch Dermatol , vol.132 , pp. 1254
    • Horn, M.1
  • 20
    • 0008101843 scopus 로고    scopus 로고
    • Myositis and rhabdomyolysis associated with concurrent use of simvastatin and nefazodone
    • Jacobson RH, Wang P, Glueck CJ. Myositis and rhabdomyolysis associated with concurrent use of simvastatin and nefazodone. JAMA 1997; 277: 296-297.
    • (1997) JAMA , vol.277 , pp. 296-297
    • Jacobson, R.H.1    Wang, P.2    Glueck, C.J.3
  • 21
    • 0031892901 scopus 로고    scopus 로고
    • Simvastatin but not pravastatm is very susceptible to interaction with the CYP3A4 inhibitor itraconazole
    • Neuvonen PJ, Kantola T, Kivistö KT. Simvastatin but not pravastatm is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 1998; 63: 332-341.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 332-341
    • Neuvonen, P.J.1    Kantola, T.2    Kivistö, K.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.