Novel G-protein-coupled receptor genes expressed in the brain: Continued discovery of important therapeutic targets

Expert Opinion on Therapeutic Targets

Volumn 6, Issue 2, 2002, Pages 185-202

  Lee, Dennis K ^a   George, Susan R ^a   O'Dowd, Brian F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Central nervous system distribution; Endogenous ligand; G protein coupled receptor; Homology cloning; Immunohistochemistry; In situ hybridisation; Orphan G protein coupled receptor; Reverse pharmacology; Transmembrane domain

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE RECEPTOR; ALPHA ADRENERGIC RECEPTOR; ANGIOTENSIN RECEPTOR; BETA CHEMOKINE; BOMBESIN RECEPTOR; BRADYKININ RECEPTOR; CANNABINOID RECEPTOR; G PROTEIN COUPLED RECEPTOR; GHRELIN; LIGAND; LYSOPHOSPHATIDIC ACID; MELANIN CONCENTRATING HORMONE; MONOCYTE CHEMOTACTIC PROTEIN; MOTILIN; NEUROMEDIN U; NEUROPEPTIDE FF; NEUROTRANSMITTER; OREXIN A; PEPTIDOLEUKOTRIENE; PROTIRELIN; PSYCHOSINE; PURINE P2Y RECEPTOR; RECEPTOR SUBTYPE; RHODOPSIN; SIGNAL PEPTIDE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSYLPHOSPHORYLCHOLINE; UNINDEXED DRUG; UROTENSIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; CELL SURFACE; CHEMOTAXIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG IDENTIFICATION; DRUG TARGETING; GENE EXPRESSION; HUMAN; LIGAND BINDING; MENTAL DISEASE; MOUSE; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RAT; RECEPTOR BINDING; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STOMACH MOTILITY; THROMBOCYTE AGGREGATION; UNINDEXED SEQUENCE; VASOCONSTRICTION; WOUND HEALING;

AMINES; AMINO ACID SEQUENCE; ANIMALS; BRAIN CHEMISTRY; CENTRAL NERVOUS SYSTEM AGENTS; DRUG DESIGN; GENE EXPRESSION PROFILING; HUMANS; LIGANDS; MAMMALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NERVE TISSUE PROTEINS; NEUROTRANSMITTER AGENTS; PROTEIN CONFORMATION; RATS; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 0036243672     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.6.2.185     Document Type: Review

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