Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor

Biochemical and Biophysical Research Communications

Volumn 283, Issue 5, 2001, Pages 1013-1018

  Mori, Masaaki ^a   Harada, Mioko ^a   Terao, Yasuko ^a   Sugo, Tsukasa ^a   Watanabe, Takuya ^a   Shimomura, Yukio ^a   Abe, Michiko ^a   Shintani, Yasushi ^a   Onda, Haruo ^a   Nishimura, Osamu ^a   Fujino, Masahiko ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

G protein coupled receptor; Melanin concentrating hormone; Orphan receptor; Receptor subtype; SLC 1; SLT

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE RECEPTOR; MELANIN CONCENTRATING HORMONE; RECEPTOR SUBTYPE; SOMATOSTATIN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CHO CELL; CORPUS CALLOSUM; DNA LIBRARY; DRUG RECEPTOR BINDING; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TARGET CELL; TISSUE DISTRIBUTION;

EID: 0034807075     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4893     Document Type: Article

References (23)

1. Orphan G-protein-coupled receptors and natural ligand discovery
2. Two important systems in energy homeostasis: Melanocortins and melanin-concentrating hormone
3. A role for melanin-concentrating hormone in the central regulation of feeding behaviour
4. Mice lacking melanin-concentrating hormone are hypophagic and lean
5. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
6. Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor
7. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
8. Molecular characterization of the melanin-concentrating-hormone receptor
9. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor
10. Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
11. Molecular cloning and functional expression of a human thyrotropin-releasing hormone (TRH) receptor gene
12. Molecular architecture of G protein-coupled receptors
13. Characterization of melanin-concentrating hormone in chum salmon pituitaries
14. Characterization of melanin-concentrating hormone from rat hypothalamus
15. Structure of the human melanin concentrating hormone mRNA
16. The rat melanin-concentrating hormone messenger ribonucleic acid encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus
17. Structure and regulation of the mouse melanin-concentrating hormone mRNA and gene
18. The melanin-concentrating hormone system of the rat brain: An immuno- and hybridization histochemical characterization
19. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat
20. Response to novelty after icv injection of melanin-concentrating hormone (MCH) in rats
21. Melanin-concentrating hormone (MCH) modifies memory retention in rats
22. Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype
23. Molecular cloning and functional characterisation of MCH2, a novel human MCH receptor