Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus

Journal of Physiology

Volumn 533, Issue 1, 2001, Pages 237-252

  Gao, Xiao Bing ^a   Van Den Pol, Anthony N ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; AMINO ACID; BACLOFEN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE; NEUROTRANSMITTER; OREXIN; PERTUSSIS TOXIN; POSTSYNAPTIC RECEPTOR; POTASSIUM; POTASSIUM CHANNEL; SODIUM; TETRODOTOXIN; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; CONTROLLED STUDY; EVOKED RESPONSE; GABAERGIC SYSTEM; GENE EXPRESSION; HORMONE ACTION; LATERAL HYPOTHALAMUS; NERVE CELL; NERVE CELL MEMBRANE POTENTIAL; NERVE EXCITABILITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SYNAPSE; SYNAPTIC INHIBITION; ACTION POTENTIAL; BRAIN NERVE CELL; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; INHIBITORY POSTSYNAPTIC POTENTIAL; NERVE CELL MEMBRANE CONDUCTANCE; POTASSIUM CURRENT; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL PATCH CLAMP;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ACTION POTENTIALS; ANIMALS; BICUCULLINE; CARRIER PROTEINS; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; FETUS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GTP-BINDING PROTEINS; HYPOTHALAMIC AREA, LATERAL; HYPOTHALAMIC HORMONES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MELANINS; NEURONS; NEUROPEPTIDES; PATCH-CLAMP TECHNIQUES; PITUITARY HORMONES; POTASSIUM; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, GLUTAMATE; RECEPTORS, NEUROPEPTIDE; SODIUM; SYNAPTIC TRANSMISSION; TETRODOTOXIN;

EID: 0035867028     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0237b.x     Document Type: Article

References (70)

1. Hypothalamic control of food intake in rats and cats
2. Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
3. Quantal analysis of EPSCs recorded from small numbers of synapses in hippocampal culture
4. The melanin-concentrating hormone system of the rat brain: An immuno- and hybridization histochemical characterization
5. Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors
6. Hypocretin/orexin and melanin-concentrating hormone-expressing cells from distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and Agouti gene-related protein systems
7. Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures
8. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
9. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
10. Multiple NPY receptors coexist in pre- and postsynaptic sites: Inhibition of GABA release in isolated self-innervating SCN neurons
11. Adenosine modulation of calcium currents and presynaptic inhibition of GABA release in suprachiasmatic and arcuate nucleus neurons
12. B autoreceptor modulation of P/Q-type calcium channels and GABA release in rat suprachiasmatic nucleus neurons
13. Detection of spontaneous synaptic events with an optimally scaled template
14. The hypocretins: Hypothalamus-specific peptides with neuro-excitatory activity
15. Melanin-concentrating hormone
16. The effect of the orexins on food intake: Comparison with neuropeptide Y, melanin-concentrating hormone and galanin
17. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
18. Forebrain origins and terminations of the medial forebrain bundle metabolically activated by rewarding stimulation or by reward-blocking doses of pimozide
19. GABA-dependent firing of glutamate-evoked action potentials at AMPA/Kainate receptors in developing hypothalamic neurons
20. Neurotrophin-3 potentiates excitatory GABAergic synaptic transmission in cultured developing hypothalamic neurones of the rat
21. Pleasure and brain activity in man
22. Modulation, slow synaptic action, and second messengers
23. Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in metabolic and endocrine regulations
24. ob mice
25. 2+ channel α1 subunits
26. 2+ channels via heterotrimeric G-proteins in neurons
27. Characterization of melanin-concentrating hormone in chum salmon pituitaries
28. Intracellular electrophysiological study of suprachiasmatic nucleus neurons in rodents: Inhibitory synaptic mechanisms
29. Protein kinase A-mediated enhancement of miniature IPSC frequency by noradrenaline in rat cerebellar stellate cells
30. NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus
31. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor
32. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
33. Alpha-adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium-channel gating
34. 2+ channels in central neurons
35. Calcium control of transmitter release at a cerebellar synapse
36. Melanin-concentrating hormone (MCH) modifies memory retention in rats
37. Intracranial self-stimulation in 3 day old rats
38. The rat melanin-concentrating hormone mRNA encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus
39. Hypocretin (orexin) deficiency in human narcolepsy
40. Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: A novel form of calcium long-term depression
41. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
42. Neurons containing hypocretin (orexin) project to multiple neuronal systems
43. A role of melanin-concentrating hormone in the central regulation of feeding behavior
44. Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase
45. Regulation of neurotransmission in the arcuate nucleus of the rat by different neuropeptide Y receptors
46. The neurophysiology of feeding
47. Investigation of the feeding effects of melanin concentrating hormone on food intake - Action independent of galanin and the melanocortin receptors
48. Molecular characterization of the melanin-concentrating-hormone receptor
49. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
50. Toward a new neurobiology of energy balance, appetite, and obesity: The anatomists weigh in
51. 2+ current in rat sympathetic neurons via a G-protein
52. Substance P and somatostatin inhibits calcium channels in rat sympathetic neurons via different G protein pathways
53. Mice lacking melanin-concentrating hormone are hypophagic and lean
54. Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor
55. Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain
56. The physiology of motivation
57. Intrahypothalamic injections of kainic acid produce feeding and drinking deficits in rats
58. Reduced number of hyocretin neurons in human epilepsy
59. Pharmacological characterization of presynaptic calcium channels using subsecond biochemical measurements of synaptosomal neurosecretion
60. Medial forebrain bundle-lateral hypothalamic area and reinforcing brain stimulation
61. Hypothalamic hypocretin (orexin): Robust innervation of the spinal cord
62. Narcolepsy, a neurodegenerative disease of the hypocretin system?
63. Pre- and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin
64. Neuropeptide Y-mediated long-term depression of excitatory activity in suprachiasmatic nucleus neurons
65. Glutamate neurons in hypothalamus regulate excitatory transmission
66. Glutamate, the dominant excitatory transmitter in neuroendocrine regulation
67. 17 Beta-estradiol regulation of melanin-concentrating hormone and neuropeptide-E-I contents in cynomolgus monkeys: A preliminary study
68. Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus
69. Presynaptic inhibition of elicited neurotransmitter release
70. Calcium channel types contributing to excitatory and inhibitory synaptic transmission between individual hypothalamic neurons