Structure-activity relationships of neuropeptide FF: Role of C-terminal regions

Peptides

Volumn 22, Issue 9, 2001, Pages 1471-1478

  Mazarguil, Honoré ^a   Gouardères, Christine ^a   Tafani, Jean André M ^b   Marcus, Delphine ^a   Kotani, Masato ^c   Mollereau, Catherine ^a   Roumy, Michel ^a   Zajac, Jean Marie ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b CHU PURPAN   (France)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Affinity; Agonist activity; Binding; NPFF receptors; Synthetic peptide

Indexed keywords

ADENYLATE CYCLASE; ALANINE DERIVATIVE; AMINO ACID; ARGININE; DIPEPTIDE; HOMOPHENYLALANINE; NEUROPEPTIDE FF; NEUROPEPTIDE FF2 RECEPTOR; NEUROPEPTIDE RECEPTOR; NOCICEPTIN; OCTAPEPTIDE; OPIATE; PHENYLALANINE; PHENYLGLYCINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG ACTIVATION; DRUG EFFECT; DRUG RECEPTOR BINDING; EXPERIMENTAL TEST; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; STRUCTURE ACTIVITY RELATION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; AUTORADIOGRAPHY; BINDING, COMPETITIVE; CELLS, CULTURED; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; HUMANS; MALE; OLIGOPEPTIDES; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE; RECEPTORS, OPIOID; SPINAL CORD; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0034889186     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00468-5     Document Type: Article

References (28)

1. Autoradiographic distribution of receptors to FLFQPQRFamide, a morphine-modulating peptide, in rat central nervous system
2. Identification and characterization of two G protein-coupled receptors for neuropeptide FF
3. Neuropeptide FF receptors in rat brain: A quantitative light-microscopic autoradiographic study using [125I][D.Tyr1, (NMe)Phe3]NPFF
4. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor
5. Anti-opioid efficacy of neuropeptide FF in morphine-tolerant mice
6. Neuropeptide FF receptors of mouse olfactory bulb: Binding properties, and stimulation of adenylate cyclase activity
7. Analogues of F8Famide resistant to degradation, with high affinity and in vivo effects
8. Structure-activity study of neuropeptide FF: Contribution of N-terminal regions to affinity and activity
9. Antinociceptive effects of intrathecally administered F8Famide and FMRFamide in the rat
10. Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues
11. 3]NPFF
12. 125I]EYF: A new high affinity radioligand to Neuropeptide FF receptors
13. Functional characterisation of a human receptor for neuropeptide FF and related peptides
14. IgG from neuropeptide FF antiserum reverses morphine tolerance in the rat
15. 2 receptors of the NPY ligands GR231118 and BIBP3226
16. Modulation of neuropeptide FF receptors by guanine nucleotides and cations in membranes of rat brain and spinal cord
17. Neuropeptide FF receptors: Structure-activity relationship, and effect of morphine
18. A human gene encoding morphine modulating peptides related to NPFF, and FMRFamide
19. 2+ channels in rat spinal ganglion neurones
20. 2+ in mouse spinal ganglion neurons
21. Neuropeptide FF, pain, and analgesia
22. Neuropeptide FF selectively attenuates the effects of nociceptin on acutely dissociated neurons of the rat dorsal raphe nucleus
23. Are neuropeptides FF and SF neurotransmitters in the rat?
24. ACTH: A short introductory review
25. Gene for pain modulatory neuropeptide NPFF: Induction in spinal cord by noxious stimuli
26. Effects of (1DMe)NPYF, a synthetic neuropeptide FF analogue, in different pain models
27. Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine
28. Neuropeptide FF receptors.