Expression and characterization of trypsinogen produced in the human male genital tract

American Journal of Pathology

Volumn 157, Issue 6, 2000, Pages 2011-2021

  Paju, Annukka ^a   Bjartell, Anders ^b   Zhang, Wan Ming ^a   Nordling, Stig ^a   Borgström, Anders ^b   Hansson, Jens ^b   Stenman, Ulf Håkan ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPSINOGEN;

ANTIGEN SPECIFICITY; ARTICLE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PURIFICATION; ENZYME RELEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE GENITAL SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINAL PLASMA; VASCULAR ENDOTHELIUM;

EID: 0033637858     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64840-7     Document Type: Article

References (40)

1. Two human trypsinogens. Purification, molecular properties and N terminal sequences
2. Nucleotide sequence of the human pancreatic trypsinogen III cDNA
3. Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase
4. Cyst fluid of ovarian cancer patients contains high concentrations of trypsinogen-2
5. Trypsinogen expression in human ovarian carcinomas
6. Expression of pancreatic trypsinogen/trypsin and cathepsin B in human cholangiocarcinomas and hepatocellular carcinomas
7. Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen
8. Expression of trypsin in vascular endothelial cells
9. Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse
10. Cloning of the cDNA encoding human brain trypsinogen and characterization of its product
11. Isolation of prostatic kallikrein hK2, also known as hGK-1, in human seminal plasma
12. Purification of a human prostate specific antigen
13. A kallikrein-like serine proteinase in prostatic fluid cleaves the predominant seminal vesicle protein
14. The human kallikrein gene family: A diversity of expression and function
15. Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein
16. Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2
17. Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis
18. A complex between prostate-specific antigen and alpha 1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: Assay of the complex improves clinical sensitivity for cancer
19. Complex formation between PSA isoenzymes and proteinase inhibitors
20. Measurement of the complex between prostate-specific antigen and alpha1-protease inhibitor in serum
21. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
22. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
23. LNCaP produces both putative zymogen and inactive, free form of prostate-specific antigen
24. Purification and characterization of different molecular forms of prostate-specific antigen in human seminal fluid
25. Radioimmunological determination and characterisation of cathodal trypsin-like immunoreactivity in normal human plasma
26. Immunoreactive anionic and cationic trypsin in human serum
27. Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens
28. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
29. Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA
30. Activation of type IV procollagenases by human tumor-associated trypsin-2
31. Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties
32. Molecular cloning of a potential proteinase activated receptor
33. 1-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2
34. Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen
35. Human prostate-specific antigen: Structural and functional similarity with serine proteinases
36. Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors
37. Production and activation of recombinant hK2 with propeptide mutations resulting in increased expression levels
38. Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids
39. Sodium, potassium, calcium, magnesium, zinc, citrate and chloride content of human prostatic and seminal fluid
40. Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors