The Binding of Ku Antigen to Homeodomain Proteins Promotes Their Phosphorylation by DNA-dependent Protein Kinase

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 16848-16856

  Schild Poulter, Caroline ^a   Pope, Louise ^a   Giffin, Ward ^a   Kochan, Jeff C ^a   Ngsee, Johnny K ^a,b   Traykova Andonova, Maya ^a   Haché, Robert J G ^a,b,c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIGENS; DNA; GENETIC ENGINEERING; PROTEINS;

GENE TRANSCRIPTION;

BIOCHEMISTRY;

COMPLEMENTARY DNA; DIMER; DNA; DNA DEPENDENT PROTEIN KINASE; DOCKING PROTEIN; HETERODIMER; HOMEODOMAIN PROTEIN; KU ANTIGEN; LYSINE; OCTAMER TRANSCRIPTION FACTOR 1; OCTAMER TRANSCRIPTION FACTOR 2; PROTEIN HOXC4; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX2; UNCLASSIFIED DRUG; CELL NUCLEUS ANTIGEN; CORTICOTROPIN; DNA BINDING PROTEIN; FUNGAL PROTEIN; GAL4 PROTEIN, S CEREVISIAE; HELICASE; HIGH AFFINITY DNA BINDING FACTOR, S CEREVISIAE; HIGH AFFINITY DNA-BINDING FACTOR, S CEREVISIAE; HOXC4 PROTEIN, HUMAN; HOXC4 PROTEIN, MOUSE; NUCLEAR PROTEIN; POU2F2 PROTEIN, HUMAN; POU2F2 PROTEIN, MOUSE; PRKDC PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; XRCC5 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; DNA LIBRARY; DNA RECOMBINATION; DNA SEQUENCE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME SUBUNIT; HOMEOBOX; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CHICKEN; DIMERIZATION; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HAMSTER; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SYNTHESIS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TICK; XENOPUS;

ADRENOCORTICOTROPIC HORMONE; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NUCLEAR; CHICKENS; CLONING, MOLECULAR; CRICETINAE; DIMERIZATION; DNA HELICASES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; JURKAT CELLS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTOR-2; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TICKS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS;

EID: 0035907345     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100768200     Document Type: Article

References (64)

1. Critchlow, S. E., and Jackson, S. P. (1998) Trends Biochem. Sci. 23, 394-398
2. Haber, J. E. (1999) Cell 97, 829-832
3. Giffin, W., Torrance, H., Rodda, D. J., Prefontaine, G. G., Pope, L., and Haché, R. J. (1996) Nature 380, 265-268
4. Smith, G. C., and Jackson, S. P. (1999) Genes Dev. 13, 916-934
5. Tuteja, R., and Tuteja, N. (2000) Crit. Rev. Biochem. Mol. Biol. 35, 1-33
6. Weaver, D. T. (1998) Curr. Biol. 8, R492-R494
7. Gu, Y., Seidl, K. J., Rathbun, G. A., Zhu, C., Manis, J. P., van der Stoep, N., Davidson, L., Cheng, H. L., Sekigucki, J. M., Frank, K., Stankope-Baker, P., Schlissel, M. S., Roth, D. B., and Alt, F. W. (1997) Immunity 7, 653-665
8. Nussenzweig, A., Chen, C., da Costa Soares, V., Sanchez, M., Sokol, K., Nussenzweig, M. C., and Li, G. C. (1996) Nature 382, 551-555
9. Ouyang, H., Nussenzweig, A., Kurimasa, A., Soares, V. C., Li, X., Cordon-Cardo, C., Li, W., Cheong, N., Nussenzweig, M., Iliakis, G., Chen, D. J., and Li, G. C. (1997) J. Exp. Med. 186, 921-929
10. Zhu, C., Bogue, M. A., Lim, D. S., Hasty, P., and Roth, D. B. (1996) Cell 86, 379-389
11. Difilippantonio, M. J., Zhu, J., Chen, H. T., Meffre, E., Nussenzweig, M. C., Max, E. E., Ried, T., and Nussenzweig, A. (2000) Nature 404, 510-514
12. Ferguson, D. O., Sekiguchi, J. M., Chang, S., Frank, K. M., Gao, Y., DePinho, R. A., and Alt, F. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 6630-6633
13. Hsu, H. L., Gilley, D., Galande, S. A., Hande, M. P., Allen, B., Kim, S. H., Li, G. C., Campisi, J., Kohwi-Shigematsu, T., and Chen, D. J. (2000) Genes Dev. 14, 2807-2812
14. Li, G. C., Ouyang, H., Li, X., Nagasawa, H., Little, J. B., Chen, D. J., Ling, C. C., Fuks, Z., and Cordon-Cardo, C. (1998) Mol. Cell 2, 1-8
15. Vogel, H., Lim, D. S., Karsenty, G., Finegold, M., and Hasty, P. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 10770-10775
16. Jin, S., Inoue, S., and Weaver, D. T. (1997) Cancer Surv. 29, 221-261
17. Hartley, K. O., Gell, D., Smith, G. C., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W., and Jackson, S. P. (1995) Cell 82, 849-856
18. Zakian, V. A. (1995) Cell 82, 685-687
19. Hammarsten, O., and Chu, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 525-530
20. Yaneva, M., Kowalewski, T., and Lieber, M. R. (1997) EMBO J. 16, 5098-5112
21. Lees-Miller, S. P. (1996) Biochem. Cell Biol. 74, 503-512
22. Giffin, W., Kwast-Welfeld, J., Rodda, D. J., Prefontaine, G. G., Traykova-Andonova, M., Zhang, Y., Weigel, N. L., Lefebvre, Y. A., and Haché, R. J. (1997) J. Biol. Chem. 272, 5647-5658
23. Anderson, C. W., and Lees-Miller, S. P. (1992) Crit. Rev. Eukaryot. Gene Exp. 2, 283-314
24. Anderson, C. W., Connelly, M. A., Lees-Miller, S. P., Lintott, L. G., Zhang, H., Sipley, J. A., Sakagushi, K., and Appella, P. (1995) in Methods in Protein Structure and Analysis (Atassi, M. Z., and Appella, E., eds) pp. 395-406, Plenum Press, New York
25. Jackson, S. P., MacDonald, J. J., Lees-Miller, S., and Tjian, R. (1990) Cell 63, 155-165
26. Giffin, W., Gong, W., Schild-Poulter, C., and Haché, R. J. (1999) Mol. Cell. Biol. 19, 4065-4078
27. Barlev, N. A., Poltoratsky, V., Owen-Hughes, T., Ying, C., Liu, L., Workman, J. L., and Berger, S. L. (1998) Mol. Cell. Biol. 18, 1349-1358
28. Leber, R., Wise, T. W., Mizuta, R., and Meek, K. (1998) J. Biol. Chem. 273, 1794-1801
29. Kharbanda, S., Pandey, P., Jin, S., Inoue, S., Bharti, A., Yuan, Z. M., Weichselbaum, R., Weaver, D., and Kufe, D. (1997) Nature 386, 732-735
30. Jin, S., Kharbanda, S., Mayer, B., Kufe, D., and Weaver, D. T. (1997) J. Biol. Chem. 272, 24763-24766
31. Modesti, M., Hesse, J. E., and Gellert, M. (1999) EMBO J. 18, 2008-2018
32. Sartorius, C. A., Takimoto, G. S., Richer, J. K., Tung, L., and Horwitz, K. B. (2000) J. Mol. Endocrinol. 24, 165-182
33. Préfontaine, G. G., Lemieux, M. E., Giffin, W., Schild-Poulter, C., Pope, L., LaCasse, E., Walker, P., and Haché, R. J. (1998) Mol. Cell. Biol. 18, 3416-3430
34. Martincic, I., Peralta, M. E., and Ngsee, J. K. (1997) J. Biol. Chem. 272, 26991-26998
35. Romero, F., Dargemont, C., Pozo, F., Reeves, W. H., Camonis, J., Gisselbrecht, S., and Fischer, S. (1996) Mol. Cell. Biol. 16, 37-44
36. Andrews, N. C., and Faller, D. V. (1991) Nucleic Acids Res. 19, 2499
37. Kornberg, T. B. (1993) J. Biol. Chem. 268, 26813-26816
38. Manak, J. R., and Scott, M. P. (1994) Dev. Suppl. 1994, 61-71
39. Gehring, W. J., Qian, Y. Q., Billeter, M., Furukubo-Tokunaga, K., Schier, A. F., Resendez-Perez, D., Affolter, M., Otting, G., and Wuthrich, K. (1994) Cell 78, 211-223
40. Gehring, W. J., Affolter, M., and Burglin, T. (1994) Annu. Rev. Biochem. 63, 487-526
41. Phelan, M. L., and Featherstone, M. S. (1997) J. Biol. Chem. 272, 8635-8643
42. Akimenko, M. A., Ekker, M., Wegner, J., Lin, W., and Westerfield, M. (1994) J. Neurosci. 14, 3475-3486
43. Clerc, R. G., Corcoran, L. M., LeBowitz, J. H., Baltimore, D., and Sharp, P. A. (1988) Genes Dev. 2, 1570-1581
44. Hinkley, C. S., Martin, J. F., Leibham, D., and Perry, M. (1992) Mol. Cell. Biol. 12, 638-649
45. Hoeffler, J. P., Meyer, T. E., Yun, Y., Jameson, J. L., and Habener, J. F. (1988) Science 242, 1430-1433
46. Tanaka, M., and Herr, W. (1990) Cell 60, 375-386
47. Pawson, T. (1995) Nature 373, 573-580
48. Faux, M. C., and Scott, J. D. (1996) Cell 85, 9-12
49. Chariot, A., Gielen, J., Merville, M. P., and Bours, V. (1999) Biochem. Pharmacol. 58, 1851-1857
50. Scott, M. P. (1999) Nature 397, 649-651
51. Vershon, A. K. (1996) Curr. Opin. Biotechnol. 7, 392-396
52. Lai, J. S., Cleary, M. A., and Herr, W. (1992) Genes Dev. 6, 2058-2065
53. Laherty, C. D., Billin, A. N., Lavinsky, R. M., Yochum, G. S., Bush, A. C., Sun, J. M., Mullen, T. M., Davie, J. R., Rose, D. W., Glass, C. K., Rosenfeld, M. G., Ayer, D. E., and Eisenman, R. N. (1998) Mol. Cell 2, 33-42
54. Xu, L., Lavinsky, R. M., Dasen, J. S., Flynn, S. E., McInerney, E. M., Mullen, T. M., Heinzel, T., Szeto, D., Korzus, E., Kurokawa, R., Aggarwal, A. K., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. (1998) Nature 395, 301-306
55. Wang, J. M., Prefontaine, G. G., Lemieux, M. E., Pope, L., Akimenko, M. A., and Haché, R. J. (1999) Mol. Cell. Biol. 19, 7106-7122
56. Edelman, G. M., and Jones, F. S. (1993) J. Biol. Chem. 268, 20683-20686
57. Ryan, A. K., and Rosenfeld, M. G. (1997) Genes Dev. 11, 1207-1225
58. Lowndes, N. F., and Murguia, J. R. (2000) Curr. Opin. Genet. Dev. 10, 17-25
59. Weinert, T. (1998) Cell 94, 555-558
60. Meighan-Mantha, R. L., Riegel, A. T., Suy, S., Harris, V., Wang, F. H., Lozano, C., Whiteside, T. L., and Kasid, U. (1999) Mol. Cell. Biochem. 199, 209-215
61. Zhao, H., Jin, S., Fan, F., Fan, W., Tong, T., and Zhan, Q. (2000) Cancer Res. 60, 6276-6280
62. Grande, M. A., van der Kraan, I., de Jong, L., and van Driel, R. (1997) J. Cell Sci. 110, 1781-1791
63. Imai, S., Nishibayashi, S., Takao, K., Tomifuji, M., Fujino, T., Hasegawa, M., and Takano, T. (1997) Mol. Biol. Cell 8, 2407-2419
64. Kim, M. K., Lesoon-Wood, L. A., Weintraub, B. D., and Chung, J. H. (1996) Mol. Cell. Biol. 16, 4366-4377