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Volumn 19, Issue 6, 1999, Pages 4065-4078

Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription

Author keywords

[No Author keywords available]

Indexed keywords

DNA DEPENDENT PROTEIN KINASE;

EID: 0032973827     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.6.4065     Document Type: Article
Times cited : (27)

References (94)
  • 2
    • 0026506720 scopus 로고
    • Transcription factor loading on the MMTV promoter: A bimodal mechanism for promoter activation
    • Archer, T. K., P. Lefebvre, R. G. Wolford, and G. L. Hager. 1992. Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science 255:1573-1576.
    • (1992) Science , vol.255 , pp. 1573-1576
    • Archer, T.K.1    Lefebvre, P.2    Wolford, R.G.3    Hager, G.L.4
  • 3
    • 0023820456 scopus 로고
    • Alterations in the U3 region of the long terminal repeat of an infectious thymotropic type B retrovirus
    • Ball, J. K., H. Diggelmann, G. A. Dekaban, G. F. Grossi, R. Semmler, P. A. Waight, and R. F. Fletcher. 1988. Alterations in the U3 region of the long terminal repeat of an infectious thymotropic type B retrovirus. J. Virol. 62:2985-2993.
    • (1988) J. Virol. , vol.62 , pp. 2985-2993
    • Ball, J.K.1    Diggelmann, H.2    Dekaban, G.A.3    Grossi, G.F.4    Semmler, R.5    Waight, P.A.6    Fletcher, R.F.7
  • 4
    • 0031913215 scopus 로고    scopus 로고
    • Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex
    • Barlev, N. A., V. Poltoratsky, T. Owen-Hughes, C. Ying, L. Liu, J. L. Workman, and S. L. Berger. 1998. Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol. 18:1349-1358.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1349-1358
    • Barlev, N.A.1    Poltoratsky, V.2    Owen-Hughes, T.3    Ying, C.4    Liu, L.5    Workman, J.L.6    Berger, S.L.7
  • 5
    • 0029848624 scopus 로고    scopus 로고
    • Chromatin structure and the regulation of gene expression: Remodeling at the MMTV promoter
    • Beato, M. 1996. Chromatin structure and the regulation of gene expression: remodeling at the MMTV promoter. J. Mol. Med. 74:711-724.
    • (1996) J. Mol. Med. , vol.74 , pp. 711-724
    • Beato, M.1
  • 6
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato, M. 1989. Gene regulation by steroid hormones. Cell 56:335-344.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 7
    • 0027468265 scopus 로고
    • Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks
    • Blier, P. R., A. J. Griffith, J. Craft, and J. A. Hardin. 1993. Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J. Biol. Chem. 268:7594-7601.
    • (1993) J. Biol. Chem. , vol.268 , pp. 7594-7601
    • Blier, P.R.1    Griffith, A.J.2    Craft, J.3    Hardin, J.A.4
  • 9
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent nonhomologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton, S. J., and S. P. Jackson. 1998. Components of the Ku-dependent nonhomologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17:1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 10
    • 0025362718 scopus 로고
    • Nuclear factor I acts as a transcription factor on the MMTV promoter but competes with steroid hormone receptors for DNA binding
    • Brüggemeier, U., L. Rogge, E. L. Winnacker, and M. Beato. 1990. Nuclear factor I acts as a transcription factor on the MMTV promoter but competes with steroid hormone receptors for DNA binding. EMBO J. 9:2233-2239.
    • (1990) EMBO J. , vol.9 , pp. 2233-2239
    • Brüggemeier, U.1    Rogge, L.2    Winnacker, E.L.3    Beato, M.4
  • 11
    • 0028607553 scopus 로고
    • The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication
    • Brush, G. S., C. W. Anderson, and T. J. Kelly. 1994. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc. Natl. Acad. Sci. USA 91: 12520-12524.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12520-12524
    • Brush, G.S.1    Anderson, C.W.2    Kelly, T.J.3
  • 12
    • 0029931782 scopus 로고    scopus 로고
    • MMTV-induced mutations in mouse mammary tumors: Their potential relevance to human breast cancer
    • Callahan, R. 1996. MMTV-induced mutations in mouse mammary tumors: their potential relevance to human breast cancer. Breast Cancer Res. Treat. 39:33-44.
    • (1996) Breast Cancer Res. Treat. , vol.39 , pp. 33-44
    • Callahan, R.1
  • 13
    • 0023283609 scopus 로고
    • The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region
    • Cato, A. C., D. Henderson, and H. Ponta. 1987. The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region. EMBO J. 6:363-368.
    • (1987) EMBO J. , vol.6 , pp. 363-368
    • Cato, A.C.1    Henderson, D.2    Ponta, H.3
  • 14
    • 0022776986 scopus 로고
    • The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction
    • Cato, A. C., R. Miksicek, G. Schutz, J. Arnemann, and M. Beato. 1986. The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. EMBO J. 5:2237-2240.
    • (1986) EMBO J. , vol.5 , pp. 2237-2240
    • Cato, A.C.1    Miksicek, R.2    Schutz, G.3    Arnemann, J.4    Beato, M.5
  • 15
    • 0023789422 scopus 로고
    • Mineralocorticoid regulation of transcription of transfected mouse mammary tumor virus DNA in cultured kidney cells
    • Cato, A. C., and J. Weinmann. 1988. Mineralocorticoid regulation of transcription of transfected mouse mammary tumor virus DNA in cultured kidney cells. J. Cell Biol. 106:2119-2125.
    • (1988) J. Cell Biol. , vol.106 , pp. 2119-2125
    • Cato, A.C.1    Weinmann, J.2
  • 16
    • 0030783087 scopus 로고    scopus 로고
    • Double strand break repair
    • Chu, G. 1997. Double strand break repair. J. Biol. Chem. 272:24097-24100.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24097-24100
    • Chu, G.1
  • 18
    • 0023636837 scopus 로고
    • Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo
    • Cordingley, M. G., A. T. Riegel, and G. L. Hager. 1987. Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo. Cell 48:261-270.
    • (1987) Cell , vol.48 , pp. 261-270
    • Cordingley, M.G.1    Riegel, A.T.2    Hager, G.L.3
  • 19
    • 0024356877 scopus 로고
    • HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex
    • de Vries, E., W. van Driel, W. G. Bergsma, A. C. Arnberg, and P. C. van der Vliet 1989. HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex. J. Mol. Biol. 208:65-68.
    • (1989) J. Mol. Biol. , vol.208 , pp. 65-68
    • De Vries, E.1    Van Driel, W.2    Bergsma, W.G.3    Arnberg, A.C.4    Van Der Vliet, P.C.5
  • 20
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 21
    • 0022620026 scopus 로고
    • Molecular cloning and characterization of mouse mammary tumor provi-ruses from a T-cell lymphoma
    • Dudley, J. P., A. Arfsten, C.-L. L. Hsu, C. Kozak, and R. Risser. 1986. Molecular cloning and characterization of mouse mammary tumor provi-ruses from a T-cell lymphoma. J. Virol. 57:385-388.
    • (1986) J. Virol. , vol.57 , pp. 385-388
    • Dudley, J.P.1    Arfsten, A.2    Hsu, C.-L.L.3    Kozak, C.4    Risser, R.5
  • 22
    • 0027246193 scopus 로고
    • Purification and characterization of a template-associated protein kinase that phosphorylates RNa polymerase II
    • Dvir, A., L. Y. Stein, B. L. Calore, and W. S. Dynan. 1993. Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J. Biol. Chem. 268:10440-10447.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10440-10447
    • Dvir, A.1    Stein, L.Y.2    Calore, B.L.3    Dynan, W.S.4
  • 23
    • 0027156140 scopus 로고
    • EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- To double-strand transitions in DNA
    • Falzon, M., J. W. Fewell, and E. L. Kuf. 1993. EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA. J. Biol. Chem. 268:10546-10552.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10546-10552
    • Falzon, M.1    Fewell, J.W.2    Kuf, E.L.3
  • 24
    • 0028897304 scopus 로고
    • DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
    • Finnie, N. J., T. M. Gottlieb, T. Blunt, P. A. Jeggo, and S. P. Jackson. 1995. DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92:320-324.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 25
    • 0023856742 scopus 로고
    • Diethylpyrocarbonate and permanganate provide evidence for an unusual DNA conformation induced by binding of the antitumour antibiotics bleomycin and phleomycin
    • Fox, K. R., and G. W. Grigg. 1988. Diethylpyrocarbonate and permanganate provide evidence for an unusual DNA conformation induced by binding of the antitumour antibiotics bleomycin and phleomycin. Nucleic Acids Res. 16:2063-2075.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 2063-2075
    • Fox, K.R.1    Grigg, G.W.2
  • 26
    • 0028898262 scopus 로고
    • Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: Subunits with homology to Ku antigen
    • Genersch, E., C. Eckerskorn, F. Lottspeich, C. Herzog, K. Kuhn, and E. Poschl. 1995. Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen. EMBO J. 14:791-800.
    • (1995) EMBO J. , vol.14 , pp. 791-800
    • Genersch, E.1    Eckerskorn, C.2    Lottspeich, F.3    Herzog, C.4    Kuhn, K.5    Poschl, E.6
  • 27
    • 0029610414 scopus 로고
    • Nuclear factor binding to a DNA sequence element that represses MMTV transcription induces a structural transition and leads to the contact of single-stranded binding proteins with DNA
    • Giffin, W., and R. J. Haché. 1995. Nuclear factor binding to a DNA sequence element that represses MMTV transcription induces a structural transition and leads to the contact of single-stranded binding proteins with DNA. DNA Cell Biol. 14:1025-1035.
    • (1995) DNA Cell Biol. , vol.14 , pp. 1025-1035
    • Giffin, W.1    Haché, R.J.2
  • 29
    • 0031054252 scopus 로고    scopus 로고
    • Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor
    • Giffin, W., J. Kwast-Welfeld, D. J. Rodda, G. G. Préfontaine, M. Traykova-Andonova, Y. Zhang, N. L. Weigel, Y. A. Lefebvre, and R. J. Hache. 1997. Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J. Biol. Chem. 272:5647-5658.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5647-5658
    • Giffin, W.1    Kwast-Welfeld, J.2    Rodda, D.J.3    Préfontaine, G.G.4    Traykova-Andonova, M.5    Zhang, Y.6    Weigel, N.L.7    Lefebvre, Y.A.8    Hache, R.J.9
  • 30
    • 0029988716 scopus 로고    scopus 로고
    • Sequence-specific DNA binding by Ku autoantigen and its effects on transcription
    • Giffin, W., H. Torrance, D. J. Rodda, G. G. Préfontaine, L. Pope, and R. J. Haché. 1996. Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature 380:265-268.
    • (1996) Nature , vol.380 , pp. 265-268
    • Giffin, W.1    Torrance, H.2    Rodda, D.J.3    Préfontaine, G.G.4    Pope, L.5    Haché, R.J.6
  • 31
    • 0028057471 scopus 로고
    • Repression of mouse mammary tumor virus transcription by a transcription factor complex. Binding of individual components to separated DNA strands
    • Giffin, W., H. Torrance, H. Safran, H. L. MacLeod, and R. J. Haché. 1994. Repression of mouse mammary tumor virus transcription by a transcription factor complex. Binding of individual components to separated DNA strands. J. Biol. Chem. 269:1449-1459.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1449-1459
    • Giffin, W.1    Torrance, H.2    Safran, H.3    MacLeod, H.L.4    Haché, R.J.5
  • 32
    • 85038153541 scopus 로고    scopus 로고
    • Unpublished observations
    • Gong, W., and R. J. G. Haché. Unpublished observations.
    • Gong, W.1    Haché, R.J.G.2
  • 33
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb, T. M., and S. P. Jackson. 1993. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72:131-142.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 34
    • 0032076127 scopus 로고    scopus 로고
    • Yeast Ku as a regulator of chromosomal DNA end structure
    • Gravel, S., M. Larrivee, P. Labrecque, and R. J. Wellinger. 1998. Yeast Ku as a regulator of chromosomal DNA end structure. Science 280:741-744.
    • (1998) Science , vol.280 , pp. 741-744
    • Gravel, S.1    Larrivee, M.2    Labrecque, P.3    Wellinger, R.J.4
  • 35
    • 0026570651 scopus 로고
    • Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA
    • Griffith, A. J., P. R. Blier, T. Mimori, and J. A. Hardin. 1992. Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J. Biol. Chem. 267:331-338.
    • (1992) J. Biol. Chem. , vol.267 , pp. 331-338
    • Griffith, A.J.1    Blier, P.R.2    Mimori, T.3    Hardin, J.A.4
  • 36
    • 0030858967 scopus 로고    scopus 로고
    • Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
    • Gu, Y., S. Jin, Y. Gao, D. T. Weaver, and F. W. Alt. 1997. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc. Natl. Acad. Sci. USA 94:8076-8081.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8076-8081
    • Gu, Y.1    Jin, S.2    Gao, Y.3    Weaver, D.T.4    Alt, F.W.5
  • 38
    • 0031930488 scopus 로고    scopus 로고
    • DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
    • Hammarsten, O., and G. Chu. 1998. DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc. Natl. Acad. Sci. USA 95:525-530.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 525-530
    • Hammarsten, O.1    Chu, G.2
  • 39
    • 0026618893 scopus 로고
    • Human prolactin regulates transfected MMTV LTR-directed gene expression in a human breast-carcinoma cell line through synergistic interaction with steroid hormones
    • Haraguchi, S., R. A. Good, R. W. Engelman, and N. K. Day. 1992. Human prolactin regulates transfected MMTV LTR-directed gene expression in a human breast-carcinoma cell line through synergistic interaction with steroid hormones. Int. J. Cancer 52:928-933.
    • (1992) Int. J. Cancer , vol.52 , pp. 928-933
    • Haraguchi, S.1    Good, R.A.2    Engelman, R.W.3    Day, N.K.4
  • 40
    • 0024215263 scopus 로고
    • Mouse mammary tumor virus proviruses in T-cell lymphomas lack a negative regulatory element in the long terminal repeat
    • Hsu, C. L., C. Fabritius, and J. Dudley. 1988. Mouse mammary tumor virus proviruses in T-cell lymphomas lack a negative regulatory element in the long terminal repeat. J. Virol. 62:4644-4652.
    • (1988) J. Virol. , vol.62 , pp. 4644-4652
    • Hsu, C.L.1    Fabritius, C.2    Dudley, J.3
  • 41
    • 0030771917 scopus 로고    scopus 로고
    • Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase
    • Huang, J., A. Nueda, S. Yoo, and W. S. Dynan. 1997. Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase. J. Biol. Chem. 272:26009-26016.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26009-26016
    • Huang, J.1    Nueda, A.2    Yoo, S.3    Dynan, W.S.4
  • 42
    • 0030476721 scopus 로고    scopus 로고
    • Mouse mammary tumor virus and mammary tumorigenesis in wild mice
    • Imai, S. 1996. Mouse mammary tumor virus and mammary tumorigenesis in wild mice. Pathol. Int. 46:919-932.
    • (1996) Pathol. Int. , vol.46 , pp. 919-932
    • Imai, S.1
  • 44
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
    • Jackson, S. P., and P. A. Jeggo. 1995. DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20: 412-415.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 45
    • 0030922250 scopus 로고    scopus 로고
    • DNA-PK: At the cross-roads of biochemistry and genetics
    • Jeggo, P. A. 1997. DNA-PK: at the cross-roads of biochemistry and genetics. Mutat. Res. 384:1-14.
    • (1997) Mutat. Res. , vol.384 , pp. 1-14
    • Jeggo, P.A.1
  • 46
    • 0030900885 scopus 로고    scopus 로고
    • Functions of the DNA-dependent protein kinase
    • Jin, S., S. Inoue, and D. T. Weaver. 1997. Functions of the DNA-dependent protein kinase. Cancer Surv. 29:221-261.
    • (1997) Cancer Surv. , vol.29 , pp. 221-261
    • Jin, S.1    Inoue, S.2    Weaver, D.T.3
  • 47
    • 0030733163 scopus 로고    scopus 로고
    • Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions
    • Jin, S., and D. T. Weaver. 1997. Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions. EMBO J. 16: 6874-6885.
    • (1997) EMBO J. , vol.16 , pp. 6874-6885
    • Jin, S.1    Weaver, D.T.2
  • 49
    • 0028855064 scopus 로고
    • DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase I
    • Kuhn, A., T. M. Gottlich, S. P. Jackson, and I. Grummt. 1995. DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I. Genes Dev. 9:193-203.
    • (1995) Genes Dev. , vol.9 , pp. 193-203
    • Kuhn, A.1    Gottlich, T.M.2    Jackson, S.P.3    Grummt, I.4
  • 50
    • 0028905581 scopus 로고
    • DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I
    • Labhart, P. 1995. DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I. Proc. Natl. Acad. Sci. USA 92:2934-2938.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2934-2938
    • Labhart, P.1
  • 51
    • 0026351193 scopus 로고
    • Multipartite structure of a negative regulatory element associated with a steroid hormone-inducible promoter
    • Lee, J. W., P. G. Moffit, K. L. Morlev, and D. O. Peterson. 1991. Multipartite structure of a negative regulatory element associated with a steroid hormone-inducible promoter. J. Biol. Chem. 266:24101-24108.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24101-24108
    • Lee, J.W.1    Moffit, P.G.2    Morlev, K.L.3    Peterson, D.O.4
  • 52
    • 0026687883 scopus 로고
    • Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
    • Lees-Miller, S. P., K. Sakaguchi, S. J. Ullrich, E. Appella, and C. W. Anderson. 1992. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol. Cell. Biol. 12:5041-5049.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5041-5049
    • Lees-Miller, S.P.1    Sakaguchi, K.2    Ullrich, S.J.3    Appella, E.4    Anderson, C.W.5
  • 53
    • 0028200998 scopus 로고
    • The 86-kDa subunit of autoantigen Ku is a somatostatin receptor regulating protein phosphatase-2A activity
    • Le Romancer, M., F. Reyl-Desmars, Y. Cherifi, C. Pigeion, S. Bottari, O. Meyer, and M. J. M. Lewin. 1994. The 86-kDa subunit of autoantigen Ku is a somatostatin receptor regulating protein phosphatase-2A activity. J. Biol. Chem. 269:17464-17468.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17464-17468
    • Le Romancer, M.1    Reyl-Desmars, F.2    Cherifi, Y.3    Pigeion, C.4    Bottari, S.5    Meyer, O.6    Lewin, M.J.M.7
  • 55
    • 0025315172 scopus 로고
    • The long terminal repeat region of the mouse mammary tumour virus contains multiple regulatory elements
    • Mink, S., H. Ponta, and A. C. Cato. 1990. The long terminal repeat region of the mouse mammary tumour virus contains multiple regulatory elements. Nucleic Acids Res. 18:2017-2024.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 2017-2024
    • Mink, S.1    Ponta, H.2    Cato, A.C.3
  • 56
    • 0023651263 scopus 로고
    • Transcriptional repression of a hormone-responsive promoter
    • Morley, K. L., M. G. Toohey, and D. O. Peterson. 1987. Transcriptional repression of a hormone-responsive promoter. Nucleic Acids Res. 15:6973-6989.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 6973-6989
    • Morley, K.L.1    Toohey, M.G.2    Peterson, D.O.3
  • 59
    • 0031471226 scopus 로고    scopus 로고
    • Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development
    • Nussenzweig, A., K. Sokol, P. Burgman, L. Li, and G. C. Li. 1997. Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc. Natl. Acad. Sci. USA 94:13588-13593.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13588-13593
    • Nussenzweig, A.1    Sokol, K.2    Burgman, P.3    Li, L.4    Li, G.C.5
  • 61
    • 0028147898 scopus 로고
    • Production and characterization of recombinant Ku antigen
    • Ono, M., P. W. Tucker, and J. D. Capra. 1994. Production and characterization of recombinant Ku antigen. Nucleic Acids Res. 22:3918-3924.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3918-3924
    • Ono, M.1    Tucker, P.W.2    Capra, J.D.3
  • 63
    • 0026045833 scopus 로고
    • Analysis of the mechanism of interaction of simian Ku protein with DNA
    • Paillard, S., and F. Strauss. 1991. Analysis of the mechanism of interaction of simian Ku protein with DNA. Nucleic Acids Res. 19:5619-5624.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5619-5624
    • Paillard, S.1    Strauss, F.2
  • 64
    • 0027394555 scopus 로고
    • Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element
    • Pearce, D., and K. Yamamoto. 1993. Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science 259:1161-1165.
    • (1993) Science , vol.259 , pp. 1161-1165
    • Pearce, D.1    Yamamoto, K.2
  • 65
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-stranded-break-repair mutant mammalian cells
    • Peterson, S. R., A. Kurimasa, M. Oshimura, W. S. Dynan, E. M. Bradbury, and D. J. Chen. 1995. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-stranded-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92:3171-3174.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 66
    • 0031690794 scopus 로고    scopus 로고
    • Purification and characterization of a cellular protein that binds to the downstream activation sequence of the strict late UL38 promoter of herpes simplex virus type 1
    • Petroski, M. D., and E. K. Wagner. 1998. Purification and characterization of a cellular protein that binds to the downstream activation sequence of the strict late UL38 promoter of herpes simplex virus type 1. J. Virol. 72:8181-8190.
    • (1998) J. Virol. , vol.72 , pp. 8181-8190
    • Petroski, M.D.1    Wagner, E.K.2
  • 67
    • 0016744751 scopus 로고
    • Dexamethasone-mediated induction of mouse mammary tumor virus RNA: A system for studying glucocorticoid action
    • Ringold, G. M., K. R. Yamamoto, G. M. Tomkins, J. M. Bishop, and H. E. Varmus. 1975. Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action. Cell 6:299-305.
    • (1975) Cell , vol.6 , pp. 299-305
    • Ringold, G.M.1    Yamamoto, K.R.2    Tomkins, G.M.3    Bishop, J.M.4    Varmus, H.E.5
  • 68
    • 0028956637 scopus 로고
    • Multi-strand binding of nuclear factors to a repressor of mouse mammary tumor virus transcription can be distinguished kinetically
    • Rodda, D. J., W. Giffin, and R. J. G. Haché. 1995. Multi-strand binding of nuclear factors to a repressor of mouse mammary tumor virus transcription can be distinguished kinetically. Biochem. Biophys. Res. Commun. 209:379-384.
    • (1995) Biochem. Biophys. Res. Commun. , vol.209 , pp. 379-384
    • Rodda, D.J.1    Giffin, W.2    Haché, R.J.G.3
  • 70
    • 0023340611 scopus 로고
    • Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor
    • Rusconi, S., and K. R. Yamamoto. 1987. Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. EMBO J. 6:1309-1315.
    • (1987) EMBO J. , vol.6 , pp. 1309-1315
    • Rusconi, S.1    Yamamoto, K.R.2
  • 71
    • 0031741234 scopus 로고    scopus 로고
    • Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: Implications for V(D)J recombination
    • Smider, V., W. K. Rathmell, G. Brown, S. Lewis, and G. Chu. 1998. Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: implications for V(D)J recombination. Mol. Cell. Biol. 18:6853-6858.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6853-6858
    • Smider, V.1    Rathmell, W.K.2    Brown, G.3    Lewis, S.4    Chu, G.5
  • 72
    • 0028112944 scopus 로고
    • Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
    • Smider, V., W. K. Rathmell, M. R. Lieber, and G. Chu. 1994. Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266:288-292.
    • (1994) Science , vol.266 , pp. 288-292
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.R.3    Chu, G.4
  • 73
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stocklin, E., M. Wissler, F. Gouilleux, and B. Groner. 1996. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383:726-728.
    • (1996) Nature , vol.383 , pp. 726-728
    • Stocklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 76
    • 0025994742 scopus 로고
    • Identification and characterization of a cis-acting element that interferes with glucocorticoid-inducible activation of the mouse mammary tumor virus promoter
    • Tanaka, H., Y. Dong, Q. Li, S. Okret, and J. A. Gustafsson. 1991. Identification and characterization of a cis-acting element that interferes with glucocorticoid-inducible activation of the mouse mammary tumor virus promoter. Proc. Natl. Acad. Sci. USA 88:5393-5397.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5393-5397
    • Tanaka, H.1    Dong, Y.2    Li, Q.3    Okret, S.4    Gustafsson, J.A.5
  • 77
    • 0024314777 scopus 로고
    • Phorbol ester-inducible T-cell-specific expression of variant mouse mammary tumor virus long terminal repeats
    • Theunissen, H. J., M. Paardekooper, L. J. Maduro, R. J. Michalides, and R. Nusse. 1989. Phorbol ester-inducible T-cell-specific expression of variant mouse mammary tumor virus long terminal repeats. J. Virol. 63:3466-3471.
    • (1989) J. Virol. , vol.63 , pp. 3466-3471
    • Theunissen, H.J.1    Paardekooper, M.2    Maduro, L.J.3    Michalides, R.J.4    Nusse, R.5
  • 78
    • 0032516876 scopus 로고    scopus 로고
    • Sequence-specific binding of Ku autoantigen to single-stranded DNA
    • Torrance, H., W. Giffin, D. J. Rodda. L. Pope, and R. J. G. Hache. 1998. Sequence-specific binding of Ku autoantigen to single-stranded DNA. J. Biol. Chem. 273:20810-20819.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20810-20819
    • Torrance, H.1    Giffin, W.2    Rodda, D.J.3    Pope, L.4    Hache, R.J.G.5
  • 79
    • 0029034248 scopus 로고
    • Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo
    • Truss, M., J. Bartsch, A. Schelbert, R. J. G. Haché, and M. Beato. 1995. Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J. 14:1737-1751.
    • (1995) EMBO J. , vol.14 , pp. 1737-1751
    • Truss, M.1    Bartsch, J.2    Schelbert, A.3    Haché, R.J.G.4    Beato, M.5
  • 80
    • 0030964526 scopus 로고    scopus 로고
    • Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
    • Tsukamoto, Y., J. Kato, and H. Ikeda. 1997. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388: 900-903.
    • (1997) Nature , vol.388 , pp. 900-903
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 81
    • 0031003383 scopus 로고    scopus 로고
    • Mechanism of DNA-dependent protein kinase inhibition by cis-diamminedichloroplatinum(II)-damaged DNA
    • Turchi, J. J., S. M. Patrick, and K. M. Henkels. 1997. Mechanism of DNA-dependent protein kinase inhibition by cis-diamminedichloroplatinum(II)-damaged DNA. Biochemistry 36:7586-7593.
    • (1997) Biochemistry , vol.36 , pp. 7586-7593
    • Turchi, J.J.1    Patrick, S.M.2    Henkels, K.M.3
  • 83
    • 0021268344 scopus 로고
    • Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates
    • Ucker, D. S., and K. R. Yamamoto. 1984. Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates. J. Biol. Chem. 259:7416-7420.
    • (1984) J. Biol. Chem. , vol.259 , pp. 7416-7420
    • Ucker, D.S.1    Yamamoto, K.R.2
  • 84
    • 0029312503 scopus 로고
    • Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer
    • van Leeuwen, F., and R. Nusse. 1995. Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer. Semin. Cancer Biol. 6:127-133.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 127-133
    • Van Leeuwen, F.1    Nusse, R.2
  • 85
    • 0024991794 scopus 로고
    • Altered mouse mammary tumor virus transcript synthesis in T-cell lymphoma cells
    • van Ooyen, A., and J. Racevskis. 1990. Altered mouse mammary tumor virus transcript synthesis in T-cell lymphoma cells. J. Virol. 64:4043-4050.
    • (1990) J. Virol. , vol.64 , pp. 4043-4050
    • Van Ooyen, A.1    Racevskis, J.2
  • 86
    • 0028060111 scopus 로고
    • Similar DNA binding properties of free P70 (KU) subunit and P70/P80 heterodimer
    • Wang, J., M. Satoh, C. H. Chou, and W. H. Reeves. 1994. Similar DNA binding properties of free P70 (KU) subunit and P70/P80 heterodimer. FEBS Lett. 351:219-224.
    • (1994) FEBS Lett. , vol.351 , pp. 219-224
    • Wang, J.1    Satoh, M.2    Chou, C.H.3    Reeves, W.H.4
  • 87
    • 0029752779 scopus 로고    scopus 로고
    • Regulation and repair of double-strand DNA breaks
    • Weaver, D. T. 1996. Regulation and repair of double-strand DNA breaks. Crit. Rev. Eukaryot. Gene Expr. 6:345-375.
    • (1996) Crit. Rev. Eukaryot. Gene Expr. , vol.6 , pp. 345-375
    • Weaver, D.T.1
  • 88
    • 0031708232 scopus 로고    scopus 로고
    • Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini
    • West, R. B., M. Yaneva, and M. R. Lieber. 1998. Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini. Mol. Cell. Biol. 18:5908-5920.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5908-5920
    • West, R.B.1    Yaneva, M.2    Lieber, M.R.3
  • 89
    • 0029740571 scopus 로고    scopus 로고
    • Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86
    • Wu, X., and M. R. Lieber. 1996. Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. Mol. Cell. Biol. 16:5186-5193.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5186-5193
    • Wu, X.1    Lieber, A.M.R.2
  • 90
    • 0025346531 scopus 로고
    • Extra mouse mammary tumor proviruses in DBA/2 mouse lymphomas acquire a selective advantage in lymphocytes by alteration in the U3 region of the long terminal repeat
    • Yanagawa, S., A. Murakami, and H. Tanaka. 1990. Extra mouse mammary tumor proviruses in DBA/2 mouse lymphomas acquire a selective advantage in lymphocytes by alteration in the U3 region of the long terminal repeat. J. Virol. 64:2474-2483.
    • (1990) J. Virol. , vol.64 , pp. 2474-2483
    • Yanagawa, S.1    Murakami, A.2    Tanaka, H.3
  • 92
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
    • Yaneva, M., T. Kowalewski, and M. R. Lieber. 1997. Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J. 16:5098-5112.
    • (1997) EMBO J. , vol.16 , pp. 5098-5112
    • Yaneva, M.1    Kowalewski, T.2    Lieber, M.R.3
  • 93
    • 0028960865 scopus 로고
    • Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
    • Zdzienicka, M. Z. 1995. Mammalian mutants defective in the response to ionizing radiation-induced DNA damage. Mutat. Res. 336:203-213.
    • (1995) Mutat. Res. , vol.336 , pp. 203-213
    • Zdzienicka, M.Z.1
  • 94
    • 0030576534 scopus 로고    scopus 로고
    • Ku 86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., M. A. Bogue, D.-S. Lim, P. Hasty, and D. B. Roth. 1996. Ku 86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86:379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5


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