메뉴 건너뛰기




Volumn 17, Issue 8, 1997, Pages 4611-4621

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: Key sequence features controlling mrna deadenylation and decay

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; MESSENGER RNA;

EID: 0030872398     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.8.4611     Document Type: Article
Times cited : (310)

References (33)
  • 1
    • 0030459516 scopus 로고    scopus 로고
    • Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC
    • Abe, R., E. Sakashita, K. Yamamoto, and H. Sakamoto. 1996. Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC. Nucleic Acids Res. 24:4895-4901.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4895-4901
    • Abe, R.1    Sakashita, E.2    Yamamoto, K.3    Sakamoto, H.4
  • 2
    • 0025934237 scopus 로고
    • Role of AUUU sequences in stabilization of granulocyte-macrophage colony-stimulating factor RNA in stimulated cells
    • Akashi, M., G. Shaw, M. Gross, M. Saito, and P. Koeffler. 1991. Role of AUUU sequences in stabilization of granulocyte-macrophage colony-stimulating factor RNA in stimulated cells. Blood 78:2005-2012.
    • (1991) Blood , vol.78 , pp. 2005-2012
    • Akashi, M.1    Shaw, G.2    Gross, M.3    Saito, M.4    Koeffler, P.5
  • 3
    • 0029053016 scopus 로고
    • Degradation of mRNA in eukaryotes
    • Beelman, C. A., and R. Parker. 1995. Degradation of mRNA in eukaryotes. Cell 81:179-183.
    • (1995) Cell , vol.81 , pp. 179-183
    • Beelman, C.A.1    Parker, R.2
  • 4
    • 0000370303 scopus 로고
    • Identification of a common nucleotide sequence in the 3′-untranslated regions of mRNA molecules specifying inflammatory mediators
    • Caput, D., B. Beutler, K. Hartog, R. Thayer, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′-untranslated regions of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83:1670-1674.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1670-1674
    • Caput, D.1    Beutler, B.2    Hartog, K.3    Thayer, R.4    Brown-Shimer, S.5    Cerami, A.6
  • 5
    • 0028153705 scopus 로고
    • Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function
    • Chen, C.-Y. A., T.-M. Chen, and A.-B. Shyu. 1994. Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function. Mol. Cell. Biol. 14:416-426.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 416-426
    • Chen, C.-Y.A.1    Chen, T.-M.2    Shyu, A.-B.3
  • 6
    • 0028131915 scopus 로고
    • Selective degradation of early-response-gene mRNAs: Functional analyses of sequence features of the AU-rich elements
    • Chen, C.-Y. A. and A.-B. Shyu. 1994. Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements. Mol. Cell. Biol. 14:8471-8482.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8471-8482
    • Chen, C.-Y.A.1    Shyu, A.-B.2
  • 7
    • 0028788194 scopus 로고
    • AU-rich elements: Characterization and importance in mRNA degradation
    • Chen, C.-Y. A., and A.-B. Shyu. 1995. AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem. Sci. 20:465-470.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 465-470
    • Chen, C.-Y.A.1    Shyu, A.-B.2
  • 8
    • 0029126879 scopus 로고
    • mRNA decay mediated by two distinct AU-rich elements from c-fos and GM-CSF transcripts: Different deadenylation kinetics and uncoupling from translation
    • Chen, C.-Y. A., N. Xu, and A.-B. Shyu. 1995. mRNA decay mediated by two distinct AU-rich elements from c-fos and GM-CSF transcripts: different deadenylation kinetics and uncoupling from translation. Mol. Cell. Biol. 15:5777-5788.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5777-5788
    • Chen, C.-Y.A.1    Xu, N.2    Shyu, A.-B.3
  • 9
    • 0027320701 scopus 로고
    • A turnover pathway for both stable and unstable mRNAs in yeast: Evidence for a requirement for deadenylation
    • Decker, C. J., and R. Parker. 1993. A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev. 7:1632-1643.
    • (1993) Genes Dev. , vol.7 , pp. 1632-1643
    • Decker, C.J.1    Parker, R.2
  • 10
    • 0021213870 scopus 로고
    • Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
    • Greenberg, M. E., and E. Ziff. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (London) 311:433-438.
    • (1984) Nature (London) , vol.311 , pp. 433-438
    • Greenberg, M.E.1    Ziff, E.2
  • 11
    • 0027523417 scopus 로고
    • Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences
    • Hamilton, B. J., E. Nagy, J. S. Malter, B. A. Arrick, and W. F. Rigby. 1993. Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences. J. Biol. Chem. 268:8881-8887.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8881-8887
    • Hamilton, B.J.1    Nagy, E.2    Malter, J.S.3    Arrick, B.A.4    Rigby, W.F.5
  • 12
    • 0001823786 scopus 로고
    • Recombinant PCR
    • M. A. Innis, D. H. Gelfand, J. J. Sninsky, and T. J. White (ed.), Academic Press, San Diego, Calif.
    • Higuchi, R. 1990. Recombinant PCR, p. 177-183. In M. A. Innis, D. H. Gelfand, J. J. Sninsky, and T. J. White (ed.), PCR protocols: a guide to methods and applications. Academic Press, San Diego, Calif.
    • (1990) PCR Protocols: A Guide to Methods and Applications , pp. 177-183
    • Higuchi, R.1
  • 13
    • 0029973094 scopus 로고    scopus 로고
    • Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
    • Jacobson, A., and S. W. Peltz. 1996. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu. Rev. Biochem. 65: 693-740.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 693-740
    • Jacobson, A.1    Peltz, S.W.2
  • 14
    • 0002799007 scopus 로고    scopus 로고
    • Poly(A) metabolism and translation: The closed loop model
    • J. Hershey, M. Mathews, and N. Sonenberg (ed.), Cold Spring Harbor Press, New York, N.Y.
    • Jacobson, A. 1996. Poly(A) metabolism and translation: the closed loop model, p. 451-480. In J. Hershey, M. Mathews, and N. Sonenberg (ed.), Translational control. Cold Spring Harbor Press, New York, N.Y.
    • (1996) Translational Control , pp. 451-480
    • Jacobson, A.1
  • 15
    • 0028089754 scopus 로고
    • AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/ A)
    • Lagnado, C. A., C. Y. Brown, and G. J. Goodall. 1994. AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/ A). Mol. Cell. Biol. 14:7984-7995.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7984-7995
    • Lagnado, C.A.1    Brown, C.Y.2    Goodall, G.J.3
  • 16
    • 0027314350 scopus 로고
    • Hel-N1: An autoimmune RNA-binding protein with specificity for 3′ uridy-late-rich untranslated regions of growth factor mRNAs
    • Levine, T. D., F. Gao, P. H. King, L. G. Andrews, and J. D. Keene. 1993. Hel-N1: an autoimmune RNA-binding protein with specificity for 3′ uridy-late-rich untranslated regions of growth factor mRNAs. Mol. Cell. Biol. 13:3494-3504.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3494-3504
    • Levine, T.D.1    Gao, F.2    King, P.H.3    Andrews, L.G.4    Keene, J.D.5
  • 17
    • 0029873536 scopus 로고    scopus 로고
    • Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
    • Ma, W.-J., S. Cheng, A. Wright, C. Campbell, and H. M. Furneaux. 1996. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J. Biol. Chem. 271:8144-8151.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8144-8151
    • Ma, W.-J.1    Cheng, S.2    Wright, A.3    Campbell, C.4    Furneaux, H.M.5
  • 18
    • 0028202495 scopus 로고
    • Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→3′ digestion of the transcript
    • Muhlrad, D., and R. Parker. 1994. Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→3′ digestion of the transcript. Genes Dev. 8:855-866.
    • (1994) Genes Dev. , vol.8 , pp. 855-866
    • Muhlrad, D.1    Parker, R.2
  • 19
  • 20
  • 21
    • 0027484122 scopus 로고
    • Purification of an AU-rich RNA binding protein from Sarcophaga peregrina (flesh fly) and its identification as a thiolase
    • Nanbu, R., T. Kubo, T. Hashimoto, and S. Natori. 1993. Purification of an AU-rich RNA binding protein from Sarcophaga peregrina (flesh fly) and its identification as a thiolase. J. Biochem. 114:432-437.
    • (1993) J. Biochem. , vol.114 , pp. 432-437
    • Nanbu, R.1    Kubo, T.2    Hashimoto, T.3    Natori, S.4
  • 22
    • 0029918710 scopus 로고    scopus 로고
    • Functional characterization of a non-AUUUa AU-rich element from the c-jun proto-oncogene mRNA: Evidence for a novel class of AU-rich elements
    • Peng, S. S.-Y., C.-Y. A. Chen, and A.-B. Shyu. 1996. Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements. Mol. Cell. Biol. 16:1490-1499.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1490-1499
    • Peng, S.S.-Y.1    Chen, C.-Y.A.2    Shyu, A.-B.3
  • 23
    • 0002888360 scopus 로고    scopus 로고
    • Dynamics of poly(A) addition and removal during development
    • J. Hershey, M. Mathews, and N. Sonenberg (ed.), Cold Spring Harbor Press, New York, N.Y.
    • Richter, J. D. 1996. Dynamics of poly(A) addition and removal during development, p. 481-504. In J. Hershey, M. Mathews, and N. Sonenberg (ed.), Translational control. Cold Spring Harbor Press, New York, N.Y.
    • (1996) Translational Control , pp. 481-504
    • Richter, J.D.1
  • 24
    • 0029165020 scopus 로고
    • mRNA stability in mammalian cells
    • Ross, J. 1995. mRNA stability in mammalian cells. Microbiol. Rev. 59:16-95.
    • (1995) Microbiol. Rev. , vol.59 , pp. 16-95
    • Ross, J.1
  • 25
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 26
    • 0026027749 scopus 로고
    • Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay
    • Shyu, A.-B., J. G. Belasco, and M. E. Greenberg. 1991. Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay. Genes Dev. 5:221-231.
    • (1991) Genes Dev. , vol.5 , pp. 221-231
    • Shyu, A.-B.1    Belasco, J.G.2    Greenberg, M.E.3
  • 27
    • 0038785142 scopus 로고    scopus 로고
    • Analysis of mRNA decay in mammalian cells
    • I. Lefkovits (ed.), Academic Press, London. United Kingdom
    • Shyu, A.-B., J. A. Garcia-Sanz, and E. Mullner. 1996. Analysis of mRNA decay in mammalian cells, p. 449-456. In I. Lefkovits (ed.), The immunology methods manual. Academic Press, London. United Kingdom.
    • (1996) The Immunology Methods Manual , pp. 449-456
    • Shyu, A.-B.1    Garcia-Sanz, J.A.2    Mullner, E.3
  • 28
    • 0024488977 scopus 로고
    • The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways
    • Shyu, A.-B., M. E. Greenberg, and J. G. Belasco. 1989. The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes Dev. 3:60-72.
    • (1989) Genes Dev. , vol.3 , pp. 60-72
    • Shyu, A.-B.1    Greenberg, M.E.2    Belasco, J.G.3
  • 29
    • 0028172176 scopus 로고
    • Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay
    • Stoecklin, G., S. Hahn, and C. Moroni. 1994. Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay. J. Biol. Chem. 269:28591-28597.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28591-28597
    • Stoecklin, G.1    Hahn, S.2    Moroni, C.3
  • 30
    • 0022137059 scopus 로고
    • Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequence
    • Treisman, R. 1985. Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequence. Cell 42:889-902.
    • (1985) Cell , vol.42 , pp. 889-902
    • Treisman, R.1
  • 31
    • 0024296025 scopus 로고
    • Removal of poly(A) tail and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequence
    • Wilson, T., and R. Treisman. 1988. Removal of poly(A) tail and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequence. Nature (London) 366:396-399.
    • (1988) Nature (London) , vol.366 , pp. 396-399
    • Wilson, T.1    Treisman, R.2
  • 33
    • 0028900073 scopus 로고
    • The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation
    • Zubiaga, A. M., J. G. Belasco, and M. E. Greenberg. 1995. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol. Cell. Biol. 15:2219-2230.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2219-2230
    • Zubiaga, A.M.1    Belasco, J.G.2    Greenberg, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.