Evidence That the Same γδ T Cells Respond during Infection-Induced and Autoimmune Inflammation

Journal of Immunology

Volumn 159, Issue 12, 1997, Pages 5787-5794

  Mukasa, Akiko ^a   Lahn, Michael ^a   Pflum, Elizabeth K ^a   Born, Willi ^a,b   O'Brien, Rebecca L ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL; ARTICLE; AUTOIMMUNE DISEASE; C3H MOUSE; CELL MOTION; GENE REARRANGEMENT; GENETICS; HYBRIDOMA; IMMUNOLOGY; LISTERIOSIS; MALE; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; ORCHITIS; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION; TESTIS;

ANIMALS; AUTOIMMUNE DISEASES; BASE SEQUENCE; CELL MOVEMENT; GENE REARRANGEMENT, DELTA-CHAIN T-CELL ANTIGEN RECEPTOR; GENE REARRANGEMENT, GAMMA-CHAIN T-CELL ANTIGEN RECEPTOR; HYBRIDOMAS; LISTERIA INFECTIONS; MALE; MICE; MICE, INBRED C3H; MOLECULAR SEQUENCE DATA; ORCHITIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; TESTIS;

EID: 0031573625     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Hiromatsu, K., Y. Yoshikai, G. Matsuzaki, S. Ohga, K. Muramori, K. Matsumoto, J. A. Bluestone, and K. Nomoto. 1992. A protective role of γ/δ T cells in primary infection with Listeria monocytogenes in mice. J. Exp. Med. 175:49.
2. O'Brien, R. L., M. P. Happ, A. Dallas, E. Palmer, R. Kubo, and W. K. Born. 1989. Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from Mycobacterium tuberculosis. Cell 57:667.
3. Emoto, M., H. Danbara, and Y. Yoshikai. 1992. Induction of γ/δ T cells in murine salmonellosis by an avirulent but not by a virulent strain of Salmonella choleraesuis. J. Exp. Med. 176:363.
4. Fu, Y.-X., C. E. Roark, K. Kelly, D. Drevets, P. Campbell, R. O'Brien, and W. Born. 1994. Immune protection and control of inflammatory tissue necrosis by γδ T cells. J. Immunol. 153:3101.
5. Skeen, M. J., and H. K. Ziegler. 1993. Induction of murine peritoneal γ/δ T cells and their role in resistance to bacterial infection. J. Exp. Med. 178:971.
6. O'Brien, R. L., Y.-X. Fu, R. Cranfill, A. Dallas, C. Reardon, J. Lang, S. R. Carding, R. Kubo, and W. Born. 1992. Heat shock protein Hsp-60 reactive γδ cells: a large, diversified T lymphocyte subset with highly focused specificity. Proc. Natl. Acad. Sci. USA 89:4348.
7. Peterman, G. M., C. Spencer, A. I. Sperling, and J. A. Bluestone. 1993. Role of γδ T cells in murine collagen-induced arthritis. J. Immunol. 151:6546.
8. Mukasa, A., K. Hioromatsu, G. Matsuzaki, R. O'Brien, W. Born, and K. Nomoto. 1995. Bacterial infection of the testis leading to autoaggressive immunity triggers apparently opposed responses of αβ and γδ T cells. J. Immunol. 155:2047.
9. Roark, C. E., M. Vollmer, P. Campbell, W. K. Born, and R. L. O'Brien. 1996. Response of a γδ-TCR monomorphic subset during bacterial infection. J. Immunol. 156:2214.
10. D'Souza, C. D., A. M. Cooper, A. A. Frank, R. J. Mazzaccaro, B. R. Bloom, and I. M. Orme. 1997. An anti-inflammatory role for γδ T lymphocytes in acquired immunity to Mycobacterium tuberculosis. J. Immunol. 158:1217.
11. Wilde, D. B., K. Roberts, K. Sturmhofel, G. Kikuchi, J. E. Coligan, and E. M. Shevach. 1992. Mouse autoreactive γ/δ T cells. I. Functional properties of autoreactive T cell hybridomas. Eur. J. Immunol. 22:483.
12. + T cells. J. Exp. Med. 172:1225.
13. Matsuzaki, G., K. Hiromatsu, Y. Yoshikai, K. Muramori, and K. Nomoto. 1993. Characterization of T-cell receptor γδ T cells appearing at the early phase of murine Listeria monocytogenes infection. Immunology 78:22.
14. Sandor, M., A. I. Sperling, G. A. Cook, J. V. Weinstock, R. G. Lynch, and J. A. Bluestone. 1995. Two waves of γδ T cells expressing different Vδ genes are recruited into schistosome-induced liver granuloma. J. Immunol. 155:275.
15. Tung, K. S. K. 1980. Autoimmunity of the testis. In Immunological Aspects of Infertility and Fertility Regulation. D. H. Dhindsa and G. F. B. Schumaker, ed. Elsevier, New York.
16. Itoh, M., C. Hiarmine, and K. Hojo. 1991. A new murine model of autoimmune orchitis induced by immunization with viable syngeneic testicular germ cells alone. I. Immunological and histological studies. Clin. Exp. Immunol. 83:137.
17. Karasuyama, H., and F. Melchors. 1988. Establishment of mouse cell lines which constitutitively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18:97.
18. White, J., M. Blackman, J. Bill, J. Kappler, P. Marrack, D. Gold, and W. Born. 1989. Two better cell lines for making hybridomas expressing specific T cell receptors. J. Immunol. 143:1822.
19. Roark, C. E., M. K. Vollmer, R. L. Cranfill, S. R. Carding, W. K. Born, and R. L. O'Brien. 1993. Liver γδ T cells: TCR junctions reveal differences in HSP-60 reactive cells in liver and spleen. J. Immunol. 150:4867.
20. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
21. Maeda, K., N. Nakanishi, B. L. Rogers, W. G. Haser, K. Shitara, H. Yoshida, Y. Takagaki, A. A. Augustin, and S. Tonegawa. 1987. Expression of the T-cell receptor γ-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reactions. Proc. Natl. Acad. Sci. USA 84:6539.
22. Arden, B., S. P. Clark, D. Kabelitz, and T. W. Mak. 1995. Mouse T-cell receptor variable gene segment families. Immunogenetics 42:501.
23. Wang, K., C.-L. Kuo, B. F. Koop, and L. Hood. 1993. The expression of mouse T-cell receptor TCRVD genes in BALB/c spleen. Immunogenetics 40:271.
24. Kalataradi, H., C. L. Eyster, A. Fry, M. K. Vollmer, Y.-X. Fu, W. K. Born, and R. L. O'Brien. 1994. Allelic differences in TCR γ-chains alter γδ T cell antigen reactivity. J. Immunol. 153:1455.
25. Goodman, T., and L. Lefrancois. 1989. Intraepithelial lymphocytes: anatomical site, not T cell receptor form, dictates phenotype and function. J. Exp. Med. 170:1569.
26. Tomonari, K. 1988. A rat antibody against a structure functionally related to the mouse T cell receptor/T3 complex. Immunogenetics 28:455.
27. + cells are a major component of the γδ T cell response to Listeria monocytogenes. J. Immunol. 156:4280.
28. Dent, A. L., L. A. Matis, F. Hooshmand, S. M. Widacki, J. A. Bluestone, and S. M. Hedrick. 1990. Self-reactive γδ T cells are eliminated in the thymus. Nature 343:714.
29. + dendritic epidermal cells revealed by Vγ3-specific monoclonal antibody. Proc. Natl. Acad. Sci. USA 86:4185.
30. Pereira, P., D. Gerber, S. Y. Huang, and S. Tonegawa. 1995. Ontogenic development and tissue distribution of Vγ1-expressing γ/δ T lymphocytes in normal mice. J. Exp. Med. 182:1921.
31. Unkeless, J. C. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580.
32. Itohara, S., N. Nakanishi, O. Kanagawa, R. Kubo, and S. Tonegawa. 1989. Monoclonal antibodies specific to native murine T-cell receptor γδ: analysis of γδ T cells during thymic ontogeny and in peripheral lymphoid organs. Proc. Natl. Acad. Sci. USA 86:5094.
33. + dendritic epidermal cells. Cell 55:837.
34. Allison, J. P., and W. L. Havran. 1991. The immunobiology of T cells with invariant γδ antigen receptors. Annu. Rev. Immunol. 9:679.
35. Goldman, J. P., D. M. Spencer, and D. H. Raulet. 1993. Ordered rearrangement of variable region genes of the T cell receptor γ locus correlates with transcription of the unrearranged genes. J. Exp. Med. 177:729.
36. + lymphocytes are derived from a common distinct lineage. J. Immunol. 151:4523.
37. Takagaki, Y., N. Nakanishi, I. Ishida, O. Kanagawa, and S. Tonegawa. 1989. T cell receptor-γ and -δ genes preferentially utilized by adult thymocytes for the surface expression. J. Immunol. 142:2112.
38. Zhang, Y., D. Cado, D. M. Asarnow, T. Komori, F. W. Alt, D. H. Raulet, and J. P. Allison. 1995. The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus. Immunity 3:439.
39. Born, W., C. Miles, J. White, R. O'Brien, J. H. Freed, P. Marrack, J. Kappler, and R. T. Kubo. 1987. Peptide sequences of T-cell receptor δ and γ chains are identical to predicted X and γ proteins. Nature 330:572.
40. + regulatory T cells. Clin. Immunol. Immunopathol. 62:210.
41. Janis, E. M., S. H. E. Kaufmann, R. H. Schwartz, and D. M. Pardoll. 1989. Activation of γδ T cells in the primary immune response to Mycobacterium tuberculosis. Science 244:713.
42. Carding, S. R. 1990. A role for γ/δ T cells in the primary immune response to influenza virus. Res. Immunol. 141:603.
43. Itohara, S., A. G. Farr, J. J. Lafaille, M. Bonneville, Y. Takagaki, W. Haas, and A. Tonegawa. 1990. Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia. Nature 343:754.
44. Hayes, S. M., A. Sirr, S. Jacob, S. G.-K., and A. Augustin. 1996. Role of IL-7 in the shaping of the pulmonary γδ T cell repertoire. J. Immunol. 156:2723.