Semi-synthetic nucleic acid-protein conjugates: Applications in life sciences and nanobiotechnology

Reviews in Molecular Biotechnology

Volumn 82, Issue 1, 2001, Pages 47-66

  Niemeyer, Christof M ^a  

^a UNIVERSITY OF BREMEN   (Germany)

Author keywords

Analytical methods; Microtechnology; Nanostructures; Nucleic acids; Proteins

Indexed keywords

DNA; NUCLEIC ACID; PROTEIN; STREPTAVIDIN;

BIOTECHNOLOGY; BIOTINYLATION; CHEMISTRY; NANOTECHNOLOGY; REVIEW; SYNTHESIS;

BIOTECHNOLOGY; BIOTINYLATION; DNA; NANOTECHNOLOGY; NUCLEIC ACIDS; PROTEINS; STREPTAVIDIN;

EID: 0035715753     PISSN: 13890352     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-0352(01)00027-7     Document Type: Article

References (115)

1. Molecular computation of solutions to combinatorial problems
2. Organization of 'nanocrystal molecules' using DNA
3. Phase imaging of moving DNA-molecules and DNA-molecules replicated in the atomic-force microscope
4. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
5. Changing functionality of surfaces by directed self-assembly using oligonucleotides - The Oligo-Tag
6. Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation
7. New developments in microarray technology
8. Antibodies in diagnostics - From immunoassays to protein chips
9. Surface plasmon resonance imaging measurements of ultrathin organic films
10. Quantifying DNA-protein interactions by double-stranded DNA arrays
11. Gene synthesis machines: DNA chemistry and its uses
12. Tumour immunotherapy: Developments and strategies
13. Cofactor regeneration for enzyme-catalysed synthesis
14. Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution
15. Electronically configurable molecular-based logic gates
16. 48000-Fold acceleration of hybridization by chemically modified oligonucleotides
17. Generation of a hybrid sequence-specific single-stranded deoxyribonuclease
18. Identification of an RNA-protein bridge spanning the ribosomal subunit interface
19. Nanotubes as nanoprobes in scanning probe microscopy
20. Antibody arrays for high-throughput screening of antibody-antigen interactions
21. Molecular engineering: An approach to the development of general capabilities for molecular manipulation
22. Electric field directed nucleic acid hybridization on microchips
23. Atomic force microscopy: A forceful way with single molecules
24. Towards a chemical etiology of nucleic acid structure
25. Disaccharid-mimetica durch enzymatische tandem-aldoladdition
26. Nucleic acid aptamers: From selection in vitro to applications in vivo
27. 'Künstliche Metabolismen' zur asymmetrischen eintopfsynthese verzweigter saccharide
28. Thermoprecipitation of streptavidin via oligonucleotide-mediated self-assembly with poly(N-isopropylacrylamide)
29. Translating biomolecular recognition into nanomechanics
30. High quality mapping of DNA-protein complex by dynamic scanning force microscopy
31. Use of maleimide-thiol coupling chemistry for efficient syntheses of oligonucleotide-enzyme conjugate hybridization probes
32. A method of one-step enzyme labelling of short oligonucleotide probes for filter hybridisation
33. Manual manufacturing of oligonucleotide, DNA, and protein microchips
34. Flexibility of DNA
35. In vitro selection methods for screening of peptide and protein libraries
36. Properties of biomolecules measured from atomic-force microscope images - A review
37. Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization
38. High sensitivity multianalyte immunoassay using covalent DNA-labeled antibodies and polymerase chain reaction
39. Small-molecule microarrays: Covalent attachment and screening of alcohol-containing small molecules on glass slides
40. Multiple ink nanolithography: Toward a multiple-Pen nano-plotter
41. Accelerated hybridization of oligonucleotides to duplex DNA
42. Analyte detection with DNA-labeled antibodies and polymerase chain-reaction
43. Escherichia coli RNA-polymerase activity observed using atomic-force microscopy
44. Reaction microarrays: A method for rapidly determining the enantiomeric excess of thousands of samples
45. Neandertal DNA sequences and the origin of modern humans
46. DNA computing on surfaces
47. Proteomanalyse-ein weg zur funktionsanalyse von proteinen
48. Protein microarrays for gene expression and antibody screening
49. Printing small molecules as microarrays and detecting protein-ligand interactions en masse
50. Printing proteins as microarrays for high-throughput function determination
51. Logical computation using algorithmic self-assembly of DNA triple-crossover molecules
52. A nanomechanical device based on the B-Z transition of DNA
53. High-throughput microarray-based enzyme-linked immunosorbent assay (ELISA)
54. A DNA-based method for rationally assembling nanoparticles into macroscopic materials
55. DNA probes on chip surfaces studied by scanning force microscopy using specific binding of colloidal gold
56. Die polymerase-kettenreaktion (Nobel-Vortrag)
57. In vitro virus: Bonding of mRNA bearing puromycin at the 3′-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro
58. Visualization of RNA crystal-growth by atomic-force microscopy
59. Peptide nucleic acid. A molecule with two identities
60. Oligonucleotide-directed self-assembly of proteins: Semisynthetic DNA-streptavidin hybrid molecules as connectors for the generation of macroscopic arrays and the construction of supramolecular bioconjugates
61. Fluorometric polymerase chain reaction (PCR) enzyme-linked immunosorbent assay for quantification of immuno-PCR products in microplates
62. Hybridization characteristics of biomolecular adaptors, covalent DNA-streptavidin conjugates
63. Covalent DNA-streptavidin conjugates as building blocks for the fabrication of novel biometallic nanostructures
64. DNA-microarrays
65. Self-assembly of DNA-streptavidin nanostructures and their use as reagents in immuno-PCR
66. DNA-directed immobilization (DDI): A new technique for fabricating protein-biochips
67. DNA-directed immobilization: Efficient, reversible and site-selective surface binding of proteins by means of covalent DNA-streptavidin conjugates
68. Evaluation of single-stranded nucleic acids as carriers in the DNA-directed assembly of macromolecules
69. Functionalization of covalent DNA-streptavidin conjugates by means of biotinylated modulator components
70. Self-assembled nanostructures based on DNA: Towards the development of a nanobiotechnology
71. Supramolecular nanocircles consisting of streptavidin and DNA
72. Bioorganic applications of semisynthetic DNA-protein conjugates
73. Nanoparticles, proteins and nucleic acids: Biotechnology meets material sciences
74. Nanostructured DNA-protein aggregates consisting of covalent oligonucleotide-streptavidin conjugates
75. Nucleic-acid supercoiling as a means for construction of switchable DNA-nanoparticle networks
76. Site-selective immobilization of gold nanoparticles functionalized with DNA oligomers
77. Hapten-functionalized DNA-streptavidin nanocircles as supramolecular reagents in a novel competitive immuno-PCR assay
78. The structural basis of ribosome activity in peptide bond synthesis
79. Rapid identification of DNA-binding proteins by mass spectrometry
80. Dendritic amplification of DNA analysis by oligonucleotide-functionalized Au-nanoparticles
81. 'Dip-Pen' nanolithography
82. Direct measurement of electrical transport through DNA molecules
83. Protein-modulated DNA electron transfer
84. Covalent protein-oligonucleotide conjugates for efficient delivery of antisense molecules
85. Advances in surface plasmon resonance biosensor analysis
86. RNA-peptide fusions for the in vitro selection of peptides and proteins
87. An array immunosensor for simultaneous detection of clinical analytes
88. Array biosensor for simultaneous identification of bacterial, viral, and protein analytes
89. Photolithographische immobilisierung von biopolymeren auf festen trägern
90. Immuno-PCR: Very sensitive antigen detection by means of specific antibody-DNA conjugates
91. Nucleic acid junctions and lattices
92. DNA engineering and its application to nanotechnology
93. Mass-sensing, multianalyte microarray immunoassay with imaging detection
94. Nucleoprotein-based nanoscale assembly
95. Enhancement of strand invasion by oligonucleotides through manipulation of backbone charge
96. Programmed materials synthesis with DNA
97. Scanometric DNA array detection with nanoparticle probes
98. The DNA-mediated formation of supramolecular mono- and multilayered nanoparticle structures
99. Preparation of symmetrical and unsymmetrical DNA-protein conjugates with DNA as a molecular scaffold
100. Immunotherapeutic perspective for bispecific antibodies
101. Structural origins of high-affinity biotin binding to streptavidin
102. Avidin-biotin technology
103. Method for the detection and isolation of biomolecules via molecular recognition using immobilized pyranosyl nucleotide supramolecular structures (WO99/15893)
104. Design and self-assembly of two-dimensional DNA crystals
105. Covalently functionalized nanotubes as nanometre-sized probes in chemistry and biology
106. Direct haplotyping of kilobase-size DNA using carbon nanotube probes
107. Torsional control of double stranded DNA branch migration
108. Opposite effect between intercalator and minor groove binding drug on the higher order structure of DNA as is visualized by fluorescence microscopy
109. A DNA-fuelled molecular machine made of DNA
110. Protein arrays and microarrays