Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization

Journal of the American Chemical Society

Volumn 122, Issue 38, 2000, Pages 9071-9077

  He, Lin ^a   Musick, Michael D ^a   Nicewarner, Sheila R ^a   Salinas, Frank G ^a   Benkovic, Stephen J ^a   Natan, Michael J ^a   Keating, Christine D ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GOLD; NANOPARTICLE; OLIGONUCLEOTIDE;

ANALYTIC METHOD; ARTICLE; COLLOID; DIELECTRIC CONSTANT; DNA DENATURATION; DNA DETERMINATION; DNA HYBRIDIZATION; NUCLEOTIDE SEQUENCE; SURFACE PLASMON RESONANCE;

EID: 0034721456     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja001215b     Document Type: Article

References (71)

1. Raether, H. Surface Plasmons on Smooth and Rough Surfaces and on Gratings, Vol. III; Springer-Verlag: Berlin Heidelberg, 1988.
2. Sambles, J. R.; Bradbery, G. W.; Yang, F. Contemp. Phys. 1991, 32, 173-183.
3. Homola, J.; Yee, S. S.; Gauglitz, G. Sens. Actuators, B 1999, 54, 3-15.
4. http://www.biacore.com/indexanim.html (accessed February 2000).
5. Fivash, M.; Towler, E. M.; Fisher, R. J. Curr. Opin. Biotechnol. 1998, 9, 97-101.
6. Malmborg, A. C.; Borrebaeck, C. A. K. J. Immnunol. Methods 1995, 183, 7-13.
7. Nice, E. C.; Catimel, B. Bioessays 1999, 4, 339-352.
8. Silin, V.; Plant, A. Trends Biotechnol. 1997, 15, 353-359.
9. Haseley, S. R.; Talaga, P.; Kamerling, J. P.; Vliegenthart, J. F. G. Anal. Biochem. 1999, 274, 203-210.
10. Choulier, L.; Rauffer-Bruyere, N.; Khalifa, B. M.; Martin, F.; Vernet, T.; Altschuh, D. Biochemistry 1999, 38, 3530-3537.
11. Pfeifer, P.; Aldinger, U.; Schwotzer, G.; Diekmann, S.; Steinrucke P. Sens. Actuators, B 1999, 54, 166-175.
12. Cooper, M. A.; Williams, D. H. Anal. Biochem. 1999, 276, 36-47.
13. Wink, T.; van Zuilen, S. J.; Bull, A.; van Bennekom, W. P. Anal. Chem. 1998, 70, 827-832.
14. Kubitschko, S.; Spinke, J.; Brückner, T.; Pohl, S.; Oranth, N. Anal. Biochem. 1997, 253, 112-122.
15. Ortega-Vinuesa, J. L.; Hidalgo-Alvarez, R.; de las Nieves, F. J.; Davey, C. L.; Newman, D. J.; Price, C. P. J. Colloid Interface Sci. 1998, 204, 300-311.
16. de Vries, E. F. A.; Schasfoort, R. B. M.; van der Plas, J.; Greve, J. Biosens. Bioelectron. 1994, 9, 509-514.
17. Jordon, C. E.; Frutos, A. G.; Thiel, A. J.; Corn, R. M. Anal. Chem. 1997, 69, 4939-4947.
18. Sadeghi, H.; Wang, B. BIA Symposium Meeting Review; Pharmacia Biosensor: Piscataway, NJ, 1992; p 56.
19. Buckle, P. E.; Davies, R. J.; Kinning, T.; Yeung, D.; Edwards, P. R.; Pollard-Knight, D.; Lowe, C. R. Biosens. Bioelectron. 1993, 8, 355-363.
20. Choi, K.; Youn, H. J.; Ha, Y. C.; Kim, K. J.; Choi, J. D. J. Microbiology 1998, 36, 43-48.
21. Lyon, L. A.; Musick, M. D.; Natan, M. J. Anal. Chem. 1998, 70, 5177-5183.
22. Lyon, L. A.; Musick, M. D.; Smith, P. C.; Reiss, B. D.; Peña, D. J.; Natan, M. J. Sens. Actuators, B 1999, 54, 118-124.
23. Lyon, L. A.; Holliway, W. D.; Natan, M. J. Rev. Sci. Instrum. 1999, 70, 2076-2081.
24. Lyon, L. A.; Peña, D. J.; Natan, M. J. J. Phys. Chem. B 1999, 103, 5826-5831.
25. He, L.; Smith, E. A.; Natan, M. J.; Keating, C. D. Manuscript in preparation.
26. Gu, J. H.; Lu, H.; Chen, Y. W.; Liu, L. Y.; Wang, P.; Ma, J. M.; Lu, Z. H. Supramol. Sci. 1998, 5, 695-698.
27. Hayat, M., Ed.; Colloidal Au: Principles, Methods and Apllications; Academic Press: San Diego, 1989; Vol. 1.
28. Bier, F. F.; Kleinjung, F.; Scheller, F. W. Sens. Actuators, B 1997, 38-39, 78-82.
29. Kukanskis, K.; Elkind, J.; Melendez, J.; Murphy, T.; Miller, G.; Garner, H. Anal. Biochem. 1999, 274, 7-17.
30. Brockman, J. M.; Frutos, A. G.; Corn, R. M. J. Am. Chem. Soc. 1999, 121, 8044-8051.
31. Peterlinz, K. A.; Georgiadis, R. M.; Herne, T. M.; Tarlov, M. J. J. Am. Chem. Soc. 1997, 119, 3401-3402.
32. Feriotto, G.; Lucci, M.; Bianchi, N.; Mischiati, C.; Gambari, R. Human Mutation 1999, 13, 390-400.
33. Kai E.; Sawata, S.; Ikebukuro, K.; Iida, T.; Honda, T.; Karube, I. Anal. Chem. 1999, 71, 796-800.
34. Thiel, A. J.; Frutos, A. G.; Jordan, C. E.; Corn, R. M.; Smith, L. M. Anal. Chem. 1997, 69, 4948-4956.
35. Piscevic, D.; Lawall, R.; Veith, M.; Liley, M.; Okahata, Y.; Knoll, W. Appl Surf. Sci. 1995, 90, 425-436.
36. Duggan, D. J.; Bittner, M.; Chen, Y.; Meltzer, P.; Trent, J. M. Nat. Genet. Suppl. 1999, 21, 10-15.
37. Grabar, K. C.; Freeman, R. G.; Hommer, M. B.; Natan, M. J. Anal. Chem. 1995, 67, 735-743.
38. Grabar, K. C.; Smith, P. C.; Musick, M. D.; Davis, J. A.; Walter, D. G.; Jackson, M. A.; Guthrie, A. P.; Natan, M. J. J. Am. Chem. Soc. 1996, 118, 1148-1153.
39. Mirkin, C. A.; Letsinger, R. L.; Mucic, R. C.; Storhoff, J. J. Nature 1996, 382, 607-609.
40. Elghanian, R.; Storhoff, J. J.; Mucic, R. C; Letsinger, R. L.; Mirkin, C. A. Science 1997, 277, 1078-1081.
41. Storhoff, J. J.; Elghanian, R.; Mucic, R. C.; Mirkin, C. A.; Letsinger, R. L. J. Am. Chem. Soc. 1998, 120, 1959-1964.
42. Storhoff, J. J.; Mirkin, C. A. Chem. Rev. 1999, 99, 1849-1862.
43. Mucic, R. C.; Storhoff, J. J.; Mirkin, C. A.; Letsinger, R. L. J. Am. Chem. Soc. 1998, 120, 12674-12675.
44. http://rsb.info.nih.gov/nih-image/ (accessed September 1999).
45. Lehninger, A. L.; Nelson, D. L.; Cox, M. M. Principles of Biochemistry, 2nd ed.; Worth Publishers: New York, 1993.
46. Adding untagged DNA probes (S3), with sequence complementary to the other half of S2, caused an indiscernible angle shift (data not shown). This is not unexpected since the mass change is relatively small, and biomolecules usually have low dielectric constants. 47
47. Refractive index of protein is approximately 1.45-1.46, while bulk Au is 0.167 + 3.44i. 48
48. http://corndog.chem.wisc.edu/fresnel/fcform.html (accessed March 1999).
49. Note that a broadening in curve C can also be perceived. This may be attributed to a slight perturbation of the alkanethiol monolayer upon heating the surface. 50,51 However, no discernible particle coverage decrease was observed on the AFM image of the control surface (exposed to the conjugates in the absence of the linking oligos) after increasing the surface temperature. Presumably, the loss of Au particles, i.e., the SPR angle shift, caused by surface perturbation from temperature elevation was negligible.
50. Murty, K. V. G. K.; Venkataramanan, M.; Pradeep, T. Langmuir 1998, 14, 5446-5456.
51. Nuzzo, R. G.; Fusco, F. A.; Allara, D. L. J. Am. Chem. Soc. 1987, 109, 2358-2368.
52. Mallamaci, M. A.; Reed, D. P.; Winkle, S. A. J. Biomol. Struct. Dyn. 1992, 10, 73-82.
53. Herne, T. M.; Tarlov, M. J. J. Am. Chem. Soc. 1997, 119, 8916-8920.
54. Jung, L. S.; Nelson, K. E.; Campbell, C. T.; Stayton, P. S.; Yee, S. S.; Perez-Luna, V.; Lopez, G. P. Sens. Actuators, B 1999, 54, 137-144.
55. Lahiri, J.; Isaacs, L.; Grzyhowski, B.; Carbeck, J. D.; Whitesides, G. M. Langmuir 1999, 15, 7186-7198.
56. Lahiri, J.; Isaacs, L.; Tien, J.; Whitesides, G. M. Anal. Chem. 1999, 71, 777-790.
57. Surface coverage was obtained by manually counting the number of Au particles present on the captured AFM images. The nonspecific-adsorption was then calculated as the ratio of the number of nonspecifically adsorbed particles to that of the surface with the linking oligonucleotides.
58. Nicewarner, S. R.; Natan, M. J.; Keating, C. D. Manuscript in preparation.
59. http://www.bioimage.com (accessed January 2000).
60. Brockman, J. M.; Frutos, A. G.; Corn, R. M. J. Am. Chem. Soc. 1999, 121, 8044-8051.
61. Strobel, H. A.; Heineman, W. R. Chemical Instrumentation: A Systematic Approach, 3rd ed.; Wiley: New York. 1989; pp 373-377.
62. Note that a 10 nM concentration of oligonucleotides has been detected by the Corn group via imaging SPR under different conditions.
63. Corn, R. M. Personal communication.
64. Cheung, V. G.; Morley, M.; Aguilar, F.; Massimi, A.; Kucherlapati, R.; Childs, G. Nat. Genet. Suppl. 1999, 21, 15-19.
65. Lipshutz, R. J.; Fodor, S. P. A.; Gingeras, T. R.; Lockhart, D. J. Nat. Genet. Suppl. 1999, 21, 20-24.
66. Bowtell, D. D. L. Nat. Genet. Suppl. 1999, 21, 25-32.
67. 2 detection limit can be expected for 45 nm diameter particles. 24 This theoretically corresponds to ∼60 copies of DNA detectable at 50 μm diameter spot size, 68 assuming 100% hybridization efficiency.
68. The capability of surface plasmon microscopy to detect surface features at sizes much smaller than 50 μm has been widely demonstrated. 69,70
69. Baida, F. I.; van Labeke, D.; Vigoureux, J. M. Phys. Rev. B: Condens. Matter 1999, 60, 7812-7815.
70. Berger, C. E. H.; Kooyman, R. P. H.; Greve. J. Rev. Sci. Instrum. 1994, 65, 2829-2836.
71. Schwarz, T.; Yeung, D.; Hawkins, E.; Heaney, P.; McDougall, A. Trends Biotechnol. 1991, 9, 339-340.