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Volumn 21, Issue 8, 2000, Pages 391-397

Immunotherapeutic perspective for bispecific antibodies

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ANTINEOPLASTIC AGENT; BISPECIFIC ANTIBODY; CD11B ANTIGEN; CD16 ANTIGEN; CD18 ANTIGEN; CD2 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD38 ANTIGEN; CD56 ANTIGEN; CD64 ANTIGEN; CD8 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DIPEPTIDYL PEPTIDASE IV; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HERMES ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MANNOSE RECEPTOR; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

EID: 0033859727     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(00)01659-5     Document Type: Review
Times cited : (137)

References (55)
  • 2
    • 0008408954 scopus 로고
    • Bispecific antibodies, R.G. Landes Publishers
    • (1995)
    • Fanger, M.W.1
  • 4
  • 8
    • 0038867807 scopus 로고    scopus 로고
    • A dimeric bispecific miniantibody combines two specificities with avidity
    • (1998) FEBS Lett. , vol.432 , pp. 45-49
    • Muller, K.M.1
  • 9
    • 0344654890 scopus 로고    scopus 로고
    • Novel tetravalent and bispecific IgG-like antibody molecules combining single-chain diabodies with the immunoglobulinγ1 Fc or CH3 region
    • (1999) FEBS Lett. , vol.454 , pp. 90-94
    • Alt, M.1
  • 10
    • 0008355115 scopus 로고    scopus 로고
    • Bispecific fusion protein, in Antibody fusion proteins (Chamow, S.M., Ashkenazi, A., eds.), Wiley-Liss
    • (1999) , pp. 189-218
    • Goldstein, J.1
  • 12
    • 0031567893 scopus 로고    scopus 로고
    • Cytolytic and cytostatic properties of an anti-human FcγRI (CD64) x epidermal growth factor bispecific fusion protein
    • (1997) J. Immunol. , vol.158 , pp. 872-879
    • Goldstein, J.1
  • 13
    • 0033986656 scopus 로고    scopus 로고
    • Resolution of cutaneous inflammation after local elimination of macrophages
    • (2000) Nat. Biotechnol. , vol.18 , pp. 48-51
    • Thepen, T.1
  • 14
    • 0027315755 scopus 로고
    • Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma
    • (1993) Nature , vol.362 , pp. 755-758
    • Tao, M.H.1    Levy, R.2
  • 16
    • 0033961486 scopus 로고    scopus 로고
    • Recombinant lipid-tagged antibody fragments as functional cell-surface receptors
    • (2000) Nat. Med. , vol.6 , pp. 223-227
    • De Kruif, J.1
  • 17
    • 0031026481 scopus 로고    scopus 로고
    • Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
    • (1997) Science , vol.275 , pp. 547-550
    • Huang, X.1
  • 19
    • 0028227751 scopus 로고
    • Cure of xenografted human tumors by bispecific monoclonal antibodies and human T cells
    • (1994) Science , vol.264 , pp. 833-835
    • Renner, C.1
  • 20
    • 0032146168 scopus 로고    scopus 로고
    • In vivo retargeting of T cell effector function by recombinant bispecific single chain Fv (anti-CD3 x anti-idiotype) induces long-term survival in the murine BCL1 lymphoma model
    • (1998) J. Immunol. , vol.161 , pp. 1454-1461
    • De Jonge, J.1
  • 22
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tum
    • (1999) J. Exp. Med. , vol.190 , pp. 355-366
    • Van Elsas, A.1
  • 23
    • 0030974954 scopus 로고    scopus 로고
    • Treatment of refractory Hodgkin's disease with an anti-CD16/CD30 bispecific antibody
    • (1997) Blood , vol.6 , pp. 2042-2047
    • Hartmann, F.1
  • 26
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • (2000) Nat. Med. , vol.6 , pp. 443-446
    • Clynes, R.A.1
  • 27
    • 0031297669 scopus 로고    scopus 로고
    • Generation of Her2/neu-specific cytotoxic neutrophils in vivo: Efficient arming of neutrophils by combined administration of granulocyte colony-stimulating factor and Fcγ Receptor I bispecific antibodies
    • (1997) J. Immunol. , vol.159 , pp. 5629-5639
    • Heijnen, I.A.F.M.1
  • 28
    • 0033564979 scopus 로고    scopus 로고
    • The FcγRI (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR γ-chain
    • (1999) Blood , vol.94 , pp. 808-817
    • Van Vugt, M.J.1
  • 29
    • 13344259328 scopus 로고    scopus 로고
    • Antigen targeting to myeloid-specific human FcγRI/CD64 triggers enhanced antibody responses in transgenic mice
    • (1996) J. Clin. Invest. , vol.97 , pp. 331-338
    • Heijnen, I.A.F.M.1
  • 30
    • 0030613845 scopus 로고    scopus 로고
    • FcαRI (CD89) as a novel trigger molecule for bispecific antibody therapy
    • (1997) Blood , vol.11 , pp. 4485-4492
    • Valerius, T.1
  • 31
    • 0008408956 scopus 로고    scopus 로고
    • FcαRI-directed bispecific antibody improves effector cell recruitment for CD20-directed immunotherapy
    • in press
    • J. Immunol.
    • Stockmeyer, B.1
  • 32
    • 0033398577 scopus 로고    scopus 로고
    • Effective phagocytosis and killing of Candida albicans via targeting FcγRI (CD64) or FcαRI (CD89) on neutrophils
    • (1999) J. Infect. Dis. , vol.197 , pp. 661-669
    • Van Spriel, A.B.1
  • 33
    • 0033625773 scopus 로고    scopus 로고
    • + liver Kupffer cells: Reappraisal of the role of immunoglobulin A in immunity
    • (2000) Nat. Med. , vol.6 , pp. 680-685
    • Van Egmond, M.1
  • 34
    • 0031114044 scopus 로고    scopus 로고
    • Bispecific antibodies overcome the opsonin-receptor mismatch of cystic fibrosis in vitro
    • (1997) J. Immunol. , vol.158 , pp. 3474-3482
    • McCormick, L.L.1
  • 35
    • 0028327382 scopus 로고
    • Targeting HIV-1 to FcγR on human phagocytes via bispecific antibodies reduces infectivity of HIV-1 to T cells
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 385-391
    • Howell, A.L.1
  • 38
    • 0032055874 scopus 로고    scopus 로고
    • Bispecific monoclonal antibody directed against both the membrane-bound complement regulator CD55 and the renal tumor-associated antigen G250 enhances C3 deposition and tumor cell lysis by complement
    • (1998) J. Immunol. , vol.160 , pp. 3437-3443
    • Blok, V.T.1
  • 39
    • 0030829805 scopus 로고    scopus 로고
    • Clinical evaluation of the bispecific antibody MDX-H210 (anti-Fc gamma RI x anti-HER-2/neu) in combination with granulocyte colony-stimulating factor (filgrastim) for treatment of advanced breast cancer
    • (1997) Cancer Immunol. Immunother. , vol.45 , pp. 207-209
    • Van Ojik, H.H.1
  • 41
    • 4244096544 scopus 로고    scopus 로고
    • Immunotherapy with bispecific antibody MDX-H210 (anti-HER-2 x anti-CD64) combined with GM-CSF in HER-2-positive hormone resistant prostate cancer
    • (1999) Proc. Am. Soc. Clin. Oncol. , pp. 1197
    • James, N.D.1
  • 42
    • 0032700376 scopus 로고    scopus 로고
    • Bispecific antibodies in cancer therapy, from the laboratory to the clinic
    • (1999) J. Immunother. , vol.22 , pp. 514-524
    • Koelemij, R.1
  • 43
    • 0032919486 scopus 로고    scopus 로고
    • A phase I study of a HER2/neu bispecific antibody with granulocyte colony-stimulating factor in patients with metastatic breast cancer that overexpresses HER2/neu
    • (1999) Cancer Immunol. Immunother. , vol.48 , pp. 9-21
    • Pullarkat, V.1
  • 44
    • 0025161953 scopus 로고
    • Preliminary trial of specific targeting therapy against malignant glioma
    • (1990) Lancet , vol.17 , pp. 368-371
    • Nitta, T.1
  • 45
    • 0028122745 scopus 로고
    • Phase I study of intravenously applied bispecific antibody in renal cell cancer patients receiving subcutaneous interleukin 2
    • (1994) Br. J. Cancer , pp. 652-661
    • Kroesen, B.J.1
  • 46
    • 0029117559 scopus 로고
    • Regression of advanced ovarian carcinoma by intraperitoneal treatment with autologous T lymphocytes retargeted by a bispecific monoclonal antibody
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1463-1469
    • Canevari, S.1
  • 47
    • 0028824721 scopus 로고
    • Clinical experience with CD3 x CD19 bispecific antibodies in patients with B cell malignancies
    • (1995) J. Hematother. , vol.4 , pp. 433-437
    • De Gast, G.C.1
  • 48
    • 0032995774 scopus 로고    scopus 로고
    • A pilot trial of GM-CSF and MDX-H210 in patients with erbB-2-positive advanced malignancies
    • (1999) J. Immunother. , vol.22 , pp. 371-379
    • Posey, J.A.1
  • 49
    • 0029095589 scopus 로고
    • Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2281-2292
    • Valone, F.H.1
  • 50
    • 0028822836 scopus 로고
    • Phase I trial of 2B1, a bispecific monoclonal antibody targeting c-erbB-2 and FcγRIII
    • (1995) Cancer Res. , vol.55 , pp. 4586-4593
    • Weiner, L.M.1
  • 52
    • 0008401999 scopus 로고    scopus 로고
    • Adoptive immunotherapy in ovarian cancer with monocyte derived activated killer cells mixed with anti HER-2/neu x anti FcγRI bispecific antibody
    • (2000) Proc. Am. Soc. Clin. Oncol. , pp. 1795
    • De Gramont, A.1
  • 53
    • 0033618624 scopus 로고    scopus 로고
    • An activating immunoreceptor complex formed by NKG2D and DAP10
    • (1999) Science , vol.285 , pp. 730-732
    • Wu, J.1
  • 54
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1
  • 55
    • 0034681121 scopus 로고    scopus 로고
    • Double trans-chromosomic mice: Maintenance of two individual human chromosome fragments containing Ig heavy and x loci and expression of fully human antibodies
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 722-727
    • Tomizuka, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.