-
1
-
-
0029901821
-
Genetic epidemiology of multiple sclerosis
-
1 Ebers GC. Genetic epidemiology of multiple sclerosis. Curr Opin Neurol 1996; 9:155-158.
-
(1996)
Curr Opin Neurol
, vol.9
, pp. 155-158
-
-
Ebers, G.C.1
-
2
-
-
0033600078
-
Progress in determining the causes and treatment of multiple sclerosis
-
2 Noseworthy JH. Progress in determining the causes and treatment of multiple sclerosis. Nature 1999; 399(Suppl):A40-A47. An excellent review of both recent and classic studies of clinical symptoms, pathogenesis and treatments.
-
(1999)
Nature
, vol.399
, Issue.SUPPL.
-
-
Noseworthy, J.H.1
-
3
-
-
0032788240
-
Benign multiple sclerosis? Clinical course, long term follow up, and assessment of prognostic factors
-
3 Hawkins SA, McDonnell GV. Benign multiple sclerosis? Clinical course, long term follow up, and assessment of prognostic factors. J Neurol Neurosurg Psychiatry 1999; 67:148-52. This is an excellent paper that follows patients with benign multiple sclerosis for over ten years. Every aspect of the clinical symptoms, onset and disease progession are discussed.
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 148-152
-
-
Hawkins, S.A.1
McDonnell, G.V.2
-
5
-
-
0033104698
-
Genetic analysis of disease subtypes and sexual dimorphisms in mouse experimental allergic encephalomyelitis (EAE): Relapsing/remitting and monophasic remitting/nonrelapsing EAE are immunogenetically distinct
-
5 Butterfield RJ, Blankenhorn EP, Roper RJ, Zachary JF, Doerge RW, Sudweeks J, et al. Genetic analysis of disease subtypes and sexual dimorphisms in mouse experimental allergic encephalomyelitis (EAE): relapsing/remitting and monophasic remitting/nonrelapsing EAE are immunogenetically distinct. J Immunol 1999; 162:3096-3102. It is suggested that the human multiple sclerosis subtypes may be controlled by modifier genes.
-
(1999)
J Immunol
, vol.162
, pp. 3096-3102
-
-
Butterfield, R.J.1
Blankenhorn, E.P.2
Roper, R.J.3
Zachary, J.F.4
Doerge, R.W.5
Sudweeks, J.6
-
6
-
-
0033615455
-
The genetic epidemiology of multiple sclerosis
-
6 Compston A. The genetic epidemiology of multiple sclerosis. Philos Trans R Soc Lond B Biol Sci 1999; 354:1623-1634. Family studies in multiple sclerosis and strategies to identify susceptibility genes are reviewed.
-
(1999)
Philos Trans R Soc Lond B Biol Sci
, vol.354
, pp. 1623-1634
-
-
Compston, A.1
-
7
-
-
0033549026
-
Familial factors influence disability in MS multiplex families
-
French Multiple Sclerosis Genetics Group
-
7 Brassat D, Azais-Vuillemin C, Yaouanq J, Semana G, Reboul J, Cournu I, et al. Familial factors influence disability in MS multiplex families. French Multiple Sclerosis Genetics Group. Neurology 1999; 52:1632-1636. Studies assessing inheritance of clinical features may help dissect susceptibility to multiple sclerosis.
-
(1999)
Neurology
, vol.52
, pp. 1632-1636
-
-
Brassat, D.1
Azais-Vuillemin, C.2
Yaouanq, J.3
Semana, G.4
Reboul, J.5
Cournu, I.6
-
8
-
-
0018355870
-
Epidemiology of multiple sclerosis in U.S. Veterans: 1. Race, sex, and geographic distribution
-
8 Kurtzke JF, Beebe GW, Norman Jr JE. Epidemiology of multiple sclerosis in U.S. veterans: 1. Race, sex, and geographic distribution. Neurology 1979; 29:1228-1235.
-
(1979)
Neurology
, vol.29
, pp. 1228-1235
-
-
Kurtzke, J.F.1
Beebe, G.W.2
Norman J.E., Jr.3
-
9
-
-
0017573360
-
Latitude, migration, and the prevalence of multiple sclerosis
-
9 Visscher BR, Detels R, Coulson AH, Malmgren RM, Dudley JP. Latitude, migration, and the prevalence of multiple sclerosis. Am J Epidemiol 1977; 106:470-475.
-
(1977)
Am J Epidemiol
, vol.106
, pp. 470-475
-
-
Visscher, B.R.1
Detels, R.2
Coulson, A.H.3
Malmgren, R.M.4
Dudley, J.P.5
-
10
-
-
0019406639
-
The incidence and prevalence of reported multiple sclerosis
-
10 Baum HM, Rothschild BB. The incidence and prevalence of reported multiple sclerosis. Ann Neurol 1981; 10:420-428.
-
(1981)
Ann Neurol
, vol.10
, pp. 420-428
-
-
Baum, H.M.1
Rothschild, B.B.2
-
11
-
-
0028100131
-
Descriptive epidemiology of multiple sclerosis in Europe in the 1980s: A critical overview
-
11 Rosati G. Descriptive epidemiology of multiple sclerosis in Europe in the 1980s: a critical overview. Ann Neurol 1994; 36 (Suppl 2):S164-S174.
-
(1994)
Ann Neurol
, vol.36
, Issue.SUPPL. 2
-
-
Rosati, G.1
-
12
-
-
0025165910
-
Multiple sclerosis in Australia and New Zealand: Are the determinants genetic or environmental?
-
12 Miller DH, Hammond SR, McLeod JG, Purdie G, Skegg DC. Multiple sclerosis in Australia and New Zealand: are the determinants genetic or environmental? [see comments]. J Neurol Neurosurg Psychiatry 1990; 53:903-905.
-
(1990)
J Neurol Neurosurg Psychiatry
, vol.53
, pp. 903-905
-
-
Miller, D.H.1
Hammond, S.R.2
McLeod, J.G.3
Purdie, G.4
Skegg, D.C.5
-
13
-
-
0028008933
-
Epidemiology of multiple sclerosis in Australia. With NSW and SA survey results
-
13 McLeod JG, Hammond SR, Hallpike JF. Epidemiology of multiple sclerosis in Australia. With NSW and SA survey results. Med J Aust 1994; 160:117-122.
-
(1994)
Med J Aust
, vol.160
, pp. 117-122
-
-
McLeod, J.G.1
Hammond, S.R.2
Hallpike, J.F.3
-
15
-
-
0033544321
-
Geographic variation of MS incidence in two prospective studies of US women
-
15 Hernan MA, Olek MJ, Ascherio A. Geographic variation of MS incidence in two prospective studies of US women. Neurology 1999; 53:1711-1718. A thorough study of incidence in multiple sclerosis. It is interesting how the incidence gradient changes over time.
-
(1999)
Neurology
, vol.53
, pp. 1711-1718
-
-
Hernan, M.A.1
Olek, M.J.2
Ascherio, A.3
-
16
-
-
0032845491
-
Genetic counselling in multiple sclerosis: Risks to sibs and children of affected individuals
-
16 Sadovnick AD, Dircks A, Ebers GC. Genetic counselling in multiple sclerosis: risks to sibs and children of affected individuals. Clin Genet 1999; 56:118-122.
-
(1999)
Clin Genet
, vol.56
, pp. 118-122
-
-
Sadovnick, A.D.1
Dircks, A.2
Ebers, G.C.3
-
17
-
-
0029121088
-
A genetic basis for familial aggregation in multiple sclerosis
-
Canadian Collaborative Study Group [see comments]
-
17 Ebers GC, Sadovnick AD, Risch NJ. A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group [see comments]. Nature 1995; 377:150-151.
-
(1995)
Nature
, vol.377
, pp. 150-151
-
-
Ebers, G.C.1
Sadovnick, A.D.2
Risch, N.J.3
-
18
-
-
0030007661
-
Evidence for genetic basis of multiple sclerosis
-
The Canadian Collaborative Study Group
-
18 Sadovnick AD, Ebers GC, Dyment DA, Risch NJ. Evidence for genetic basis of multiple sclerosis. The Canadian Collaborative Study Group. Lancet 1996; 347:1728-1730.
-
(1996)
Lancet
, vol.347
, pp. 1728-1730
-
-
Sadovnick, A.D.1
Ebers, G.C.2
Dyment, D.A.3
Risch, N.J.4
-
19
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
19 Risch N. Linkage strategies for genetically complex traits. I. Multilocus models [see comments]. Am J Hum Genet 1990; 46:222-228.
-
(1990)
Am J Hum Genet
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
20
-
-
0027537583
-
A population-based study of multiple sclerosis in twins: Update
-
20 Sadovnick AD, Armstrong H, Rice GP, Bulman D, Hashimoto L, Paty DW, et al. A population-based study of multiple sclerosis in twins: update. Ann Neurol 1993; 33:281-285.
-
(1993)
Ann Neurol
, vol.33
, pp. 281-285
-
-
Sadovnick, A.D.1
Armstrong, H.2
Rice, G.P.3
Bulman, D.4
Hashimoto, L.5
Paty, D.W.6
-
21
-
-
0027164123
-
Familial recurrence risks and inheritance of multiple sclerosis
-
21 Sadovnick AD. Familial recurrence risks and inheritance of multiple sclerosis. Curr Opin Neurol Neurosurg 1993; 6:189-194.
-
(1993)
Curr Opin Neurol Neurosurg
, vol.6
, pp. 189-194
-
-
Sadovnick, A.D.1
-
22
-
-
0031722705
-
The human genome project aims for 2003
-
22 Goodman L. The human genome project aims for 2003. Genome Res 1998; 8:997-999.
-
(1998)
Genome Res
, vol.8
, pp. 997-999
-
-
Goodman, L.1
-
23
-
-
1842333889
-
Genotype and phenotype in cystic fibrosis
-
passim
-
23 Tsui LC, Durie P. Genotype and phenotype in cystic fibrosis. Hosp Pract (Off Ed) 1997; 32:115-118, 123-9, 134, passim.
-
(1997)
Hosp Pract (Off Ed)
, vol.32
, pp. 115-118
-
-
Tsui, L.C.1
Durie, P.2
-
24
-
-
0032248397
-
Pathological mechanisms in Huntington's disease and other polyglutamine expansion diseases
-
24 Lunkes A, Trottier Y, Mandel JL. Pathological mechanisms in Huntington's disease and other polyglutamine expansion diseases. Essays Biochem 1998; 33:149-63.
-
(1998)
Essays Biochem
, vol.33
, pp. 149-163
-
-
Lunkes, A.1
Trottier, Y.2
Mandel, J.L.3
-
25
-
-
0033382503
-
The genetics of complex diseases
-
25 Thomson G, Esposito MS. The genetics of complex diseases. Trends Cell Biol 1999; 9:M17-M20. Discussion of techniques utilized for identifying genes involved in Mendelian traits and the application to complex traits.
-
(1999)
Trends Cell Biol
, vol.9
-
-
Thomson, G.1
Esposito, M.S.2
-
26
-
-
0025008677
-
Linkage strategies for genetically complex traits. II. The power of affected relative pairs
-
26 Risch N. Linkage strategies for genetically complex traits. II. The power of affected relative pairs [see comments]. Am J Hum Genet 1990; 46:229-241.
-
(1990)
Am J Hum Genet
, vol.46
, pp. 229-241
-
-
Risch, N.1
-
27
-
-
0031739621
-
Etiology and pathogenesis of multiple sclerosis
-
27 Sorensen TL, Ransohoff RM. Etiology and pathogenesis of multiple sclerosis. Semin Neurol 1998; 18:287-294.
-
(1998)
Semin Neurol
, vol.18
, pp. 287-294
-
-
Sorensen, T.L.1
Ransohoff, R.M.2
-
28
-
-
0032742379
-
Modelling multiple sclerosis
-
28 Ebers G. Modelling multiple sclerosis [news; comment]. Nat Genet 1999; 23:258-259.
-
(1999)
Nat Genet
, vol.23
, pp. 258-259
-
-
Ebers, G.1
-
29
-
-
0033978459
-
Animal models for autoimmune demyelinating disorders of the nervous system
-
29 Gold I, Hartung I, Toyka KV. Animal models for autoimmune demyelinating disorders of the nervous system. Mol Med Today 2000; 6:88-91.
-
(2000)
Mol Med Today
, vol.6
, pp. 88-91
-
-
Gold, I.1
Hartung, I.2
Toyka, K.V.3
-
30
-
-
0032772860
-
Immunopathogenesis of multiple sclerosis: The role of T cells
-
30 Martino G, Hartung HP. Immunopathogenesis of multiple sclerosis: the role of T cells. Curr Opin Neurol 1999; 12:309-321. The molecular aspects of T cells and their potential role in multiple sclerosis pathogenesis are discussed.
-
(1999)
Curr Opin Neurol
, vol.12
, pp. 309-321
-
-
Martino, G.1
Hartung, H.P.2
-
31
-
-
0032915806
-
Molecular mimicry and multiple sclerosis: Degenerate T-cell recognition and the induction of autoimmunity
-
31 Gran B, Hemmer B, Vergelli M, McFarland HF, Martin R. Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity. Ann Neurol 1999; 45:559-567. An interesting hypothesis about T cell immunology and multiple sclerosis.
-
(1999)
Ann Neurol
, vol.45
, pp. 559-567
-
-
Gran, B.1
Hemmer, B.2
Vergelli, M.3
McFarland, H.F.4
Martin, R.5
-
32
-
-
0032765901
-
Regression and spreading of self-recognition during the development of autoimmune demyelinating disease
-
32 Tuohy VK, Yu M, Yin L, Kawczak JA, Kinkel PR. Regression and spreading of self-recognition during the development of autoimmune demyelinating disease. J Autoimmun 1999; 13:11-20.
-
(1999)
J Autoimmun
, vol.13
, pp. 11-20
-
-
Tuohy, V.K.1
Yu, M.2
Yin, L.3
Kawczak, J.A.4
Kinkel, P.R.5
-
33
-
-
0034642534
-
Cbl-b regulates the CD28 dependence of T-cell activation
-
33 Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, et al. Cbl-b regulates the CD28 dependence of T-cell activation. Nature 2000; 403:216-220. Cbl-b knock out mice and the immunological consequences are investigated thoroughly in this paper.
-
(2000)
Nature
, vol.403
, pp. 216-220
-
-
Chiang, Y.J.1
Kole, H.K.2
Brown, K.3
Naramura, M.4
Fukuhara, S.5
Hu, R.J.6
-
34
-
-
0033980474
-
Multiple sclerosis as a neuronal disease
-
34 Waxman SG. Multiple sclerosis as a neuronal disease. Arch Neurol 2000; 57:22-24. A discussion of axonal pathology and its potential role in multiple sclerosis.
-
(2000)
Arch Neurol
, vol.57
, pp. 22-24
-
-
Waxman, S.G.1
-
35
-
-
0032837941
-
The path to damage in multiple sclerosis
-
35 McFarland HF. The path to damage in multiple sclerosis [editorial]. Ann Neurol 1999; 46:141-142.
-
(1999)
Ann Neurol
, vol.46
, pp. 141-142
-
-
McFarland, H.F.1
-
36
-
-
0032716144
-
Axonal degeneration in the pathogenesis of multiple sclerosis
-
36 Silber E, Sharief MK. Axonal degeneration in the pathogenesis of multiple sclerosis. J Neurol Sci 1999; 170:11-18. This paper raises questions about the causes and effects of axonal damage.
-
(1999)
J Neurol Sci
, vol.170
, pp. 11-18
-
-
Silber, E.1
Sharief, M.K.2
-
37
-
-
0033386468
-
Infectious etiology in multiple sclerosis: The debate continues
-
37 Gonzalez-Scorano F, Rima B. Infectious etiology in multiple sclerosis: the debate continues. Trends Microbiol 1999; 7:475-477.
-
(1999)
Trends Microbiol
, vol.7
, pp. 475-477
-
-
Gonzalez-Scorano, F.1
Rima, B.2
-
38
-
-
0032702603
-
The distinction blurs between an autoimmune versus microbial hypothesis in multiple sclerosis
-
38 Hafler DA. The distinction blurs between an autoimmune versus microbial hypothesis in multiple sclerosis. J Clin Invest 1999; 104:527-529. A discussion of potential causes of epitope spreading.
-
(1999)
J Clin Invest
, vol.104
, pp. 527-529
-
-
Hafler, D.A.1
-
40
-
-
0032402940
-
Inheritance of susceptibility to multiple sclerosis
-
40 Sawcer S, Goodfellow PN. Inheritance of susceptibility to multiple sclerosis. Curr Opin Immunol 1998; 10:697-703.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 697-703
-
-
Sawcer, S.1
Goodfellow, P.N.2
-
41
-
-
0033031926
-
Candidate autoantigens in multiple sclerosis
-
41 Schmidt S. Candidate autoantigens in multiple sclerosis. Mult Scler 1999; 5:147-60. The plausibility of T cell pathway genes and myelin related proteins as candidates is discussed.
-
(1999)
Mult Scler
, vol.5
, pp. 147-160
-
-
Schmidt, S.1
-
42
-
-
0033617472
-
A new look at major histocompatibility and autoimmune disease
-
42 Ridgway WM, Fasso M, Fathman CG. A new look at major histocompatibility and autoimmune disease. Science 1999; 284:749-751. A brief review of important aspects of the molecular action of major histocompatibility and its relation to diabetes and nod mice.
-
(1999)
Science
, vol.284
, pp. 749-751
-
-
Ridgway, W.M.1
Fasso, M.2
Fathman, C.G.3
-
43
-
-
0028227135
-
Human leukocyte antigen studies in multiple sclerosis
-
43 Hillert J. Human leukocyte antigen studies in multiple sclerosis. Ann Neurol 1994; 36(Suppl):S15-S17.
-
(1994)
Ann Neurol
, vol.36
, Issue.SUPPL.
-
-
Hillert, J.1
-
44
-
-
0033384955
-
Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster
-
44 Allcock RJ, de la Concha EG, Femandez-Arquero M, Vigil P, Conejero L, Arroyo R, et al. Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster. Hum Immunol 1999; 60:1266-1273. An interesting look at which locus within the human leukocyte antigen is responsible for the known DR2 association with multiple sclerosis.
-
(1999)
Hum Immunol
, vol.60
, pp. 1266-1273
-
-
Allcock, R.J.1
De La Concha, E.G.2
Femandez-Arquero, M.3
Vigil, P.4
Conejero, L.5
Arroyo, R.6
-
45
-
-
0032880710
-
Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosis
-
45 Fernandez-Arquero M, Arroyo R, Rubio A, Martin C, Vigil P, Conejero L, et al. Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosis. Neurology 1999; 53:1361-1363.
-
(1999)
Neurology
, vol.53
, pp. 1361-1363
-
-
Fernandez-Arquero, M.1
Arroyo, R.2
Rubio, A.3
Martin, C.4
Vigil, P.5
Conejero, L.6
-
46
-
-
0032739607
-
Gene polymorphism at position -308 of the tumor necrosis factor alpha promoter is not associated with disease progression in multiple sclerosis patients
-
46 Maurer M, Kruse N, Giess R, Kyriallis K, Toyka KV, Rieckmann P. Gene polymorphism at position -308 of the tumor necrosis factor alpha promoter is not associated with disease progression in multiple sclerosis patients. J Neurol 1999; 246:949-954.
-
(1999)
J Neurol
, vol.246
, pp. 949-954
-
-
Maurer, M.1
Kruse, N.2
Giess, R.3
Kyriallis, K.4
Toyka, K.V.5
Rieckmann, P.6
-
47
-
-
0033556578
-
Comparison of clinical and demographic features between affected pairs of Italian multiple sclerosis multiplex families; relation to tumour necrosis factor genomic polymorphisms
-
47 Trojano M, Liguori M, De Robertis F, Stella A, Guanti G, Avolio C, et al. Comparison of clinical and demographic features between affected pairs of Italian multiple sclerosis multiplex families; relation to tumour necrosis factor genomic polymorphisms. J Neurol Sci 1999; 162:194-200. Interesting results that need confirmation in a larger dataset.
-
(1999)
J Neurol Sci
, vol.162
, pp. 194-200
-
-
Trojano, M.1
Liguori, M.2
De Robertis, F.3
Stella, A.4
Guanti, G.5
Avolio, C.6
-
48
-
-
0032724614
-
Tumor necrosis factor 2 allele does not contribute to increased tumor necrosis factor-alpha production in Sardinian multiple sclerosis
-
48 Sotgiu S, Pugliatti M, Serra C, Rosati G, Dolei A, Marrosu MG. Tumor necrosis factor 2 allele does not contribute to increased tumor necrosis factor-alpha production in Sardinian multiple sclerosis. Ann Neurol 1999; 46:799-800.
-
(1999)
Ann Neurol
, vol.46
, pp. 799-800
-
-
Sotgiu, S.1
Pugliatti, M.2
Serra, C.3
Rosati, G.4
Dolei, A.5
Marrosu, M.G.6
-
49
-
-
0344076307
-
HLA-DRB1 and tumor necrosis factor gene polymorphisms in Japanese patients with multiple sclerosis
-
49 Ma JJ, Nishimura M, Mine H, Saji H, Ohta M, Saida K, et al. HLA-DRB1 and tumor necrosis factor gene polymorphisms in Japanese patients with multiple sclerosis. J Neuroimmunol 1998; 92:109-112.
-
(1998)
J Neuroimmunol
, vol.92
, pp. 109-112
-
-
Ma, J.J.1
Nishimura, M.2
Mine, H.3
Saji, H.4
Ohta, M.5
Saida, K.6
-
51
-
-
0032964170
-
The CTLA-4 gene is associated with multiple sclerosis
-
51 Ligers A, Xu C, Saarinen S, Hillert J, Olerup O. The CTLA-4 gene is associated with multiple sclerosis. J Neuroimmunol 1999; 97:182-190.
-
(1999)
J Neuroimmunol
, vol.97
, pp. 182-190
-
-
Ligers, A.1
Xu, C.2
Saarinen, S.3
Hillert, J.4
Olerup, O.5
-
52
-
-
0032719489
-
CTLA-4 gene polymorphism may modulate disease in Japanese multiple sclerosis patients
-
52 Fukazawa T, Yanagawa T, Kikuchi S, Yabe I, Sasaki H, Hamada T, et al. CTLA-4 gene polymorphism may modulate disease in Japanese multiple sclerosis patients. J Neurol Sci 1999; 171:49-55.
-
(1999)
J Neurol Sci
, vol.171
, pp. 49-55
-
-
Fukazawa, T.1
Yanagawa, T.2
Kikuchi, S.3
Yabe, I.4
Sasaki, H.5
Hamada, T.6
-
53
-
-
0033992193
-
Cytokines in genetic susceptibility to multiple sclerosis: A candidate gene approach
-
French Multiple Sclerosis Genetics Group
-
53 Reboul J, Mertens C, Levillayer F, Eichenbaum-Voline S, Vilkoren T, Cournu I, et al. Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group. J Neuroimmunol 2000; 102:107-112. Candidate gene approaches may be of particular value in the next few years of multiple sclerosis genetics research.
-
(2000)
J Neuroimmunol
, vol.102
, pp. 107-112
-
-
Reboul, J.1
Mertens, C.2
Levillayer, F.3
Eichenbaum-Voline, S.4
Vilkoren, T.5
Cournu, I.6
-
54
-
-
0033050206
-
Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients
-
54 Sciacca FL, Ferri C, Vandenbroeck K, Veglia F, Gobbi C, Martinelli F, et al. Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients. Neurology 1999; 52:1896-1898.
-
(1999)
Neurology
, vol.52
, pp. 1896-1898
-
-
Sciacca, F.L.1
Ferri, C.2
Vandenbroeck, K.3
Veglia, F.4
Gobbi, C.5
Martinelli, F.6
-
55
-
-
0032832164
-
No evidence for association of multiple sclerosis with the complement factors C6 and C7
-
55 Chataway J, Sawcer S, Sherman D, Hobart M, Fernie B, Coraddu F, et al. No evidence for association of multiple sclerosis with the complement factors C6 and C7. J Neuroimmunol 1999; 99:150-156.
-
(1999)
J Neuroimmunol
, vol.99
, pp. 150-156
-
-
Chataway, J.1
Sawcer, S.2
Sherman, D.3
Hobart, M.4
Fernie, B.5
Coraddu, F.6
-
56
-
-
0032746023
-
Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis
-
56 Pickard C, Mann C, Sinnott P, Boggild M, Hawkins C, Strange RC, et al. Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis. J Neuroimmunol 1999; 101:207-210.
-
(1999)
J Neuroimmunol
, vol.101
, pp. 207-210
-
-
Pickard, C.1
Mann, C.2
Sinnott, P.3
Boggild, M.4
Hawkins, C.5
Strange, R.C.6
-
57
-
-
0033613075
-
A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain
-
57 Shields DC, Schaecher KE, Saido TC, Banik NL. A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain. Proc Natl Acad Sci USA 1999; 96:11486-11491. An interesting novel candidate gene.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11486-11491
-
-
Shields, D.C.1
Schaecher, K.E.2
Saido, T.C.3
Banik, N.L.4
-
58
-
-
0034642499
-
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
-
58 Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature 2000; 403:211-216. The counterpart of [33•].
-
(2000)
Nature
, vol.403
, pp. 211-216
-
-
Bachmaier, K.1
Krawczyk, C.2
Kozieradzki, I.3
Kong, Y.Y.4
Sasaki, T.5
Oliveira-Dos-Santos, A.6
-
59
-
-
0033975024
-
Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D(3)
-
59 Mattner F, Smiroldo S, Galbiati F, Muller M, Di Lucia P, Poliani PL, et al. Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D(3). Eur J Immunol 2000; 30:498-508.
-
(2000)
Eur J Immunol
, vol.30
, pp. 498-508
-
-
Mattner, F.1
Smiroldo, S.2
Galbiati, F.3
Muller, M.4
Di Lucia, P.5
Poliani, P.L.6
-
60
-
-
0033563742
-
Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese
-
60 Fukazawa T, Yabe I, Kikuchi S, Sasaki H, Hamada T, Miyasaka K, et al. Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese. J Neurol Sci 1999; 166:47-52. Interesting to see whether associations found in Japanese patients can be confirmed in Northern European patients.
-
(1999)
J Neurol Sci
, vol.166
, pp. 47-52
-
-
Fukazawa, T.1
Yabe, I.2
Kikuchi, S.3
Sasaki, H.4
Hamada, T.5
Miyasaka, K.6
-
61
-
-
0034620555
-
Genetic analysis of vitamin D related genes in Canadian multiple sclerosis genes
-
61 Steckley JL, Dyment DA, Sadovnick AD, Risch N, Hayes C, Ebers GC, et al and the Canadian Collaborative Study Group. Genetic analysis of vitamin D related genes in Canadian multiple sclerosis genes. Neurology 2000; 54:729-732.
-
(2000)
Neurology
, vol.54
, pp. 729-732
-
-
Steckley, J.L.1
Dyment, D.A.2
Sadovnick, A.D.3
Risch, N.4
Hayes, C.5
Ebers, G.C.6
-
62
-
-
0032856198
-
More evidence that founder effects exist in the European population
-
62 Chataway J, Sawcer S, Feakes R, Coraddu F, Broadley S, Gray J, et al. More evidence that founder effects exist in the European population [letter]. Eur J Hum Genet 1999; 7:623-624.
-
(1999)
Eur J Hum Genet
, vol.7
, pp. 623-624
-
-
Chataway, J.1
Sawcer, S.2
Feakes, R.3
Coraddu, F.4
Broadley, S.5
Gray, J.6
-
63
-
-
0033960291
-
Increased numbers of CCR5+ interferon-gamma- and tumor necrosis factor-alpha-secreting T lymphocytes in multiple sclerosis patients
-
63 Strunk T, Bubel S, Mascher B, Schlenke P, Kirchner H, Wandinger KP. Increased numbers of CCR5+ interferon-gamma- and tumor necrosis factor-alpha-secreting T lymphocytes in multiple sclerosis patients. Ann Neurol 2000; 47:269-73.
-
(2000)
Ann Neurol
, vol.47
, pp. 269-273
-
-
Strunk, T.1
Bubel, S.2
Mascher, B.3
Schlenke, P.4
Kirchner, H.5
Wandinger, K.P.6
-
64
-
-
0031444113
-
The CCR5 deletion mutation fails to protect against multiple sclerosis
-
64 Bennetts BH, Teutsch SM, Buhler MM, Heard RN, Stewart GJ. The CCR5 deletion mutation fails to protect against multiple sclerosis. Hum Immunol 1997; 58:52-69.
-
(1997)
Hum Immunol
, vol.58
, pp. 52-69
-
-
Bennetts, B.H.1
Teutsch, S.M.2
Buhler, M.M.3
Heard, R.N.4
Stewart, G.J.5
-
65
-
-
0032859555
-
APOE and risk of cognitive impairment in multiple sclerosis
-
65 Oliveri RL, Cittadella R, Sibilia G, Manna I, Valentine P, Gambardella A, et al. APOE and risk of cognitive impairment in multiple sclerosis. Acta Neurol Scand 1999; 100:290-295.
-
(1999)
Acta Neurol Scand
, vol.100
, pp. 290-295
-
-
Oliveri, R.L.1
Cittadella, R.2
Sibilia, G.3
Manna, I.4
Valentine, P.5
Gambardella, A.6
-
66
-
-
0032588236
-
Association of the APOE epsilon4 allele with disease activity in multiple sclerosis
-
66 Evangelou N, Jackson M, Beeson D, Palace J. Association of the APOE epsilon4 allele with disease activity in multiple sclerosis. J Neurol Neurosurg Psychiatry 1999; 67:203-205.
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 203-205
-
-
Evangelou, N.1
Jackson, M.2
Beeson, D.3
Palace, J.4
-
67
-
-
0033046020
-
A screen of candidates from peaks of linkage: Evidence for the involvement of myeloperoxidase in multiple sclerosis
-
67 Chataway J, Sawcer S, Feakes R, Coraddu F, Broadley S, Jones HB, et al. A screen of candidates from peaks of linkage: evidence for the involvement of myeloperoxidase in multiple sclerosis. J Neuroimmunol 1999; 98:208-213. A thorough analysis of a number of candidate genes, integrating genome scans and candidate gene methodologies.
-
(1999)
J Neuroimmunol
, vol.98
, pp. 208-213
-
-
Chataway, J.1
Sawcer, S.2
Feakes, R.3
Coraddu, F.4
Broadley, S.5
Jones, H.B.6
-
68
-
-
0032892619
-
Chromosome 19 locus apolipoprotein C-ll association with multiple sclerosis
-
68 Zouali H, Faure-Delanef L, Lucotte G. Chromosome 19 locus apolipoprotein C-ll association with multiple sclerosis. Mult Scler 1999; 5:134-136.
-
(1999)
Mult Scler
, vol.5
, pp. 134-136
-
-
Zouali, H.1
Faure-Delanef, L.2
Lucotte, G.3
-
69
-
-
15844368830
-
A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
-
69 Sawcer S, Jones HB, Feakes R, Gray J, Smaldon N, Chataway J, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996; 13:464-468.
-
(1996)
Nat Genet
, vol.13
, pp. 464-468
-
-
Sawcer, S.1
Jones, H.B.2
Feakes, R.3
Gray, J.4
Smaldon, N.5
Chataway, J.6
-
70
-
-
17344367913
-
Genomewide scan of multiple sclerosis in Finnish multiplex families
-
70 Kuokkanen S, Gschwend M, Rioux JD, Daly MJ, Terwilliger JD, Tienari PJ, et al. Genomewide scan of multiple sclerosis in Finnish multiplex families. Am J Hum Genet 1997; 61:1379-1387.
-
(1997)
Am J Hum Genet
, vol.61
, pp. 1379-1387
-
-
Kuokkanen, S.1
Gschwend, M.2
Rioux, J.D.3
Daly, M.J.4
Terwilliger, J.D.5
Tienari, P.J.6
-
71
-
-
0009573338
-
A complete genomic screen for multiple sclerosis underscores a role for the major histocompatabitity complex
-
The Multiple Sclerosis Genetics Group [see comments]
-
71 Haines JL, Ter-Minassian M, Bazyk A, Gusella JF, Kim DJ, Terwedow H, et al. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatabitity complex. The Multiple Sclerosis Genetics Group [see comments]. Nat Genet 1996; 13:469-471.
-
(1996)
Nat Genet
, vol.13
, pp. 469-471
-
-
Haines, J.L.1
Ter-Minassian, M.2
Bazyk, A.3
Gusella, J.F.4
Kim, D.J.5
Terwedow, H.6
-
72
-
-
15844366743
-
A full genome search in multiple sclerosis
-
72 Ebers GC, Kukay K, Bulman DE, Sadovnick AD, Rice G, Anderson C, et al. A full genome search in multiple sclerosis [see comments]. Nat Genet 1996; 13:472-476.
-
(1996)
Nat Genet
, vol.13
, pp. 472-476
-
-
Ebers, G.C.1
Kukay, K.2
Bulman, D.E.3
Sadovnick, A.D.4
Rice, G.5
Anderson, C.6
-
73
-
-
0031748194
-
Clinical demographics of multiplex families with multiple sclerosis
-
73 Multiple Sclerosis Genetics Group. Clinical demographics of multiplex families with multiple sclerosis. Ann Neurol 1998; 43:530-534.
-
(1998)
Ann Neurol
, vol.43
, pp. 530-534
-
-
-
74
-
-
0031656952
-
Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis?
-
74 Kalman B, Alder H. Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis? Acta Neurol Scand 1998; 98:232-237.
-
(1998)
Acta Neurol Scand
, vol.98
, pp. 232-237
-
-
Kalman, B.1
Alder, H.2
-
75
-
-
0345580611
-
Nitric oxide, mitochondria and neurological disease
-
75 Heales SJ, Bolanos JP, Stewart VC, Brookes PS, Land JM, Clark JB. Nitric oxide, mitochondria and neurological disease. Biochim Biophys Acta 1999; 1410:215-228. Discussion of the involvement of the mitochondrial respiratory chain in the pathogenesis of neurological diseases such as Alzheimer's, and multiple sclerosis.
-
(1999)
Biochim Biophys Acta
, vol.1410
, pp. 215-228
-
-
Heales, S.J.1
Bolanos, J.P.2
Stewart, V.C.3
Brookes, P.S.4
Land, J.M.5
Clark, J.B.6
-
76
-
-
0032897253
-
Large scale screening of the mitochondrial DNA reveals no pathogenic mutations but a haplotype associated with multiple sclerosis in Caucasians
-
76 Kalman B, Li S, Chatterjee D, O'Connor J, Voehl MR, Brown MD, el al. Large scale screening of the mitochondrial DNA reveals no pathogenic mutations but a haplotype associated with multiple sclerosis in Caucasians. Acta Neurol Scand 1999; 99:16-25.
-
(1999)
Acta Neurol Scand
, vol.99
, pp. 16-25
-
-
Kalman, B.1
Li, S.2
Chatterjee, D.3
O'Connor, J.4
Voehl, M.R.5
Brown, M.D.6
-
77
-
-
14844358372
-
Do HLA genes play a prominent role in determining T cell receptor V alpha segment usage in humans?
-
77 Gulwani-Akolkar B, Shi B, Akolkar PN, Ito K, Bias WB, Silver J. Do HLA genes play a prominent role in determining T cell receptor V alpha segment usage in humans? J Immunol 1995; 154:3843-3851.
-
(1995)
J Immunol
, vol.154
, pp. 3843-3851
-
-
Gulwani-Akolkar, B.1
Shi, B.2
Akolkar, P.N.3
Ito, K.4
Bias, W.B.5
Silver, J.6
-
78
-
-
0032605624
-
Diversity of V delta-J delta gene rearrangement in peripheral blood lymphocytes and intrathecal IgG synthesis in multiple sclerosis
-
78 Michalowska-Wender G, Nowak J, Losy J, Januszkiewicz D, Wender M. Diversity of V delta-J delta gene rearrangement in peripheral blood lymphocytes and intrathecal IgG synthesis in multiple sclerosis. Folia Neuropathol 1999; 37:113-116.
-
(1999)
Folia Neuropathol
, vol.37
, pp. 113-116
-
-
Michalowska-Wender, G.1
Nowak, J.2
Losy, J.3
Januszkiewicz, D.4
Wender, M.5
-
79
-
-
0027170328
-
Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis
-
79 Utz U, Biddison WE, McFarland HF, McFarlin DE, Flerlage M, Martin R. Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis [see comments]. Nature 1993; 364:243-247.
-
(1993)
Nature
, vol.364
, pp. 243-247
-
-
Utz, U.1
Biddison, W.E.2
McFarland, H.F.3
McFarlin, D.E.4
Flerlage, M.5
Martin, R.6
-
80
-
-
0033546652
-
Does a shift in the T-cell receptor repertoire precede the onset of MS?
-
80 Haegert DG, Cowan T, Murray TJ, Gadag V, O'Connor P. Does a shift in the T-cell receptor repertoire precede the onset of MS? Neurology 1999; 53:485-490.
-
(1999)
Neurology
, vol.53
, pp. 485-490
-
-
Haegert, D.G.1
Cowan, T.2
Murray, T.J.3
Gadag, V.4
O'Connor, P.5
-
81
-
-
0032803760
-
Concepts of viral pathogenesis of multiple sclerosis
-
81 Meinl E. Concepts of viral pathogenesis of multiple sclerosis. Curr Opin Neurol 1999; 12:303-307. Mainly a discussion of HHV-6 and multiple sclerosis associated retrovirus.
-
(1999)
Curr Opin Neurol
, vol.12
, pp. 303-307
-
-
Meinl, E.1
-
82
-
-
0033083404
-
Herpesviruses - A rationale for antiviral treatment in multiple sclerosis
-
82 Bergstrom T. Herpesviruses - a rationale for antiviral treatment in multiple sclerosis. Antiviral Res 1999; 41:1-19. Proposed models of pathogenesis and a potential treatment are linked.
-
(1999)
Antiviral Res
, vol.41
, pp. 1-19
-
-
Bergstrom, T.1
-
83
-
-
0032846754
-
A pilot study on the antibodies to HHV-6 variants and HHV-7 in CSF of MS patients
-
83 Ongradi J, Rajda C, Marodi CL, Csiszar A, Vecsei L. A pilot study on the antibodies to HHV-6 variants and HHV-7 in CSF of MS patients. J Neurovirol 1999; 5:529-532.
-
(1999)
J Neurovirol
, vol.5
, pp. 529-532
-
-
Ongradi, J.1
Rajda, C.2
Marodi, C.L.3
Csiszar, A.4
Vecsei, L.5
-
84
-
-
0032728026
-
The association of the human herpesvirus-6 and MS
-
84 Friedman JE, Lyons MJ, Cu G, Ablashl DV, Whitman JE, Edgar M, et al. The association of the human herpesvirus-6 and MS. Mult Scler 1999; 5:355-362.
-
(1999)
Mult Scler
, vol.5
, pp. 355-362
-
-
Friedman, J.E.1
Lyons, M.J.2
Cu, G.3
Ablashl, D.V.4
Whitman, J.E.5
Edgar, M.6
-
85
-
-
0032441219
-
Human Herpesvirus-6 (HHV-6) infection in multiple sclerosis: A preliminary report
-
85 Ablashi DV, Lapps W, Kaplan M, Whitman JE, Richert JR, Pearson GR. Human Herpesvirus-6 (HHV-6) infection in multiple sclerosis: a preliminary report. Mult Scler 1998; 4:490-496.
-
(1998)
Mult Scler
, vol.4
, pp. 490-496
-
-
Ablashi, D.V.1
Lapps, W.2
Kaplan, M.3
Whitman, J.E.4
Richert, J.R.5
Pearson, G.R.6
-
86
-
-
0032837685
-
Human herpesvirus 6 is latent in peripheral blood of patients with relapsing-remitting multiple sclerosis
-
86 Rotola A, Cassai E, Tola MR, Granieri E, Di Luca D. Human herpesvirus 6 is latent in peripheral blood of patients with relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 1999; 67:529-531.
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 529-531
-
-
Rotola, A.1
Cassai, E.2
Tola, M.R.3
Granieri, E.4
Di Luca, D.5
-
87
-
-
0032943438
-
Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis
-
87 Goldberg SH, Albright AV, Lisak RP, Gonzalez-Scarano F. Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis. J Neurovirol 1999; 5:134-139.
-
(1999)
J Neurovirol
, vol.5
, pp. 134-139
-
-
Goldberg, S.H.1
Albright, A.V.2
Lisak, R.P.3
Gonzalez-Scarano, F.4
-
88
-
-
0032860267
-
Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients
-
88 Mirandola P, Stefan A, Brambilla E, Campadelli-Fiume G, Grimaldi LM. Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients. Neurology 1999; 53:1367-1368.
-
(1999)
Neurology
, vol.53
, pp. 1367-1368
-
-
Mirandola, P.1
Stefan, A.2
Brambilla, E.3
Campadelli-Fiume, G.4
Grimaldi, L.M.5
-
89
-
-
0033985785
-
Does Chlamydia pneumoniae play a role in the pathogenesis of multiple sclerosis?
-
89 Stratton CW, Mitchell WM, Sriram S. Does Chlamydia pneumoniae play a role in the pathogenesis of multiple sclerosis? [editorial]. J Med Microbiol 2000; 49:1-3.
-
(2000)
J Med Microbiol
, vol.49
, pp. 1-3
-
-
Stratton, C.W.1
Mitchell, W.M.2
Sriram, S.3
-
90
-
-
0033043952
-
Chlamydia: A role for multiple sclerosis or more confusion?
-
90 Gilden DH. Chlamydia: a role for multiple sclerosis or more confusion? Ann Neurol 1999; 46:4-5. A brief review of Chlamydia studies in multiple sclerosis research.
-
(1999)
Ann Neurol
, vol.46
, pp. 4-5
-
-
Gilden, D.H.1
-
91
-
-
0033011178
-
Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis
-
91 Sriram S, Stratton CW, Yao S, Tharp A, Ding L, Bannan JD, et al. Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis. Ann Neurol 1999; 46:6-14.
-
(1999)
Ann Neurol
, vol.46
, pp. 6-14
-
-
Sriram, S.1
Stratton, C.W.2
Yao, S.3
Tharp, A.4
Ding, L.5
Bannan, J.D.6
-
92
-
-
0033985658
-
Failure to detect Chlamydia pneumoniae in the central nervous system of patients with MS
-
92 Boman J, Roblin PM, Sundstrom P, Sandstrom M, Hammerschlag MR. Failure to detect Chlamydia pneumoniae in the central nervous system of patients with MS. Neurology 2000; 54:265-266.
-
(2000)
Neurology
, vol.54
, pp. 265-266
-
-
Boman, J.1
Roblin, P.M.2
Sundstrom, P.3
Sandstrom, M.4
Hammerschlag, M.R.5
-
93
-
-
0033049329
-
Endogenous retroviruses: Are they the cause of multiple sclerosis?
-
93 Fujinami RS, Libbey JE. Endogenous retroviruses: are they the cause of multiple sclerosis? Trends Microbiol 1999; 7:263-264.
-
(1999)
Trends Microbiol
, vol.7
, pp. 263-264
-
-
Fujinami, R.S.1
Libbey, J.E.2
-
94
-
-
0032786127
-
Nidovirus infections: Experimental model systems of human neurologic diseases
-
94 Lavi E, Schwartz T, Jin YP, Fu L. Nidovirus infections: experimental model systems of human neurologic diseases. J Neuropathol Exp Neurol 1999; 58:1197-206.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1197-1206
-
-
Lavi, E.1
Schwartz, T.2
Jin, Y.P.3
Fu, L.4
-
95
-
-
0033023304
-
Herpes zoster and multiple sclerosis
-
95 Ross RT, Cheang M, Landry G, Klassen L, Doerksen K. Herpes zoster and multiple sclerosis. Can J Neurol Sci 1999; 26:29-32. A large-scale epidemiological approach to answering questions of viruses in multiple sclerosis.
-
(1999)
Can J Neurol Sci
, vol.26
, pp. 29-32
-
-
Ross, R.T.1
Cheang, M.2
Landry, G.3
Klassen, L.4
Doerksen, K.5
-
96
-
-
0028606220
-
Aspects of canine distemper virus and measles virus encephalomyelitis
-
96 Summers BA, Appel MJ. Aspects of canine distemper virus and measles virus encephalomyelitis. Neuropathol Appl Neurobiol 1994; 20:525-534.
-
(1994)
Neuropathol Appl Neurobiol
, vol.20
, pp. 525-534
-
-
Summers, B.A.1
Appel, M.J.2
-
97
-
-
0030626495
-
The implications of Epstein-Barr virus in multiple sclerosis - A review
-
97 Munch M, Hvas J, Christensen T, Moller-Larsen A, Haahr S. The implications of Epstein-Barr virus in multiple sclerosis - a review. Acta Neurol Scand Suppl 1997; 169:59-64.
-
(1997)
Acta Neurol Scand Suppl
, vol.169
, pp. 59-64
-
-
Munch, M.1
Hvas, J.2
Christensen, T.3
Moller-Larsen, A.4
Haahr, S.5
|