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Volumn 53, Issue 8, 1999, Pages 358-370

The genetics of multiple sclerosis. A review

Author keywords

Genetics; Multiple sclerosis; Pathogenesis

Indexed keywords

CYTOKINE; GLYCOPROTEIN; GROWTH FACTOR; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 0033197842     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(99)80107-3     Document Type: Article
Times cited : (52)

References (183)
  • 1
    • 0028228832 scopus 로고
    • Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles
    • Allen M, Sandberg-Wollheim M, Sjogrn K, et al. Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles. Hum Immunol 1994 ; 39 : 41-8.
    • (1994) Hum Immunol , vol.39 , pp. 41-48
    • Allen, M.1    Sandberg-Wollheim, M.2    Sjogrn, K.3
  • 2
    • 0000439545 scopus 로고
    • Multiple sclerosis in Israel: Prevalence among immigrants and native inhabitants
    • Alter M, Hapern L, Kurland LT, et al. Multiple sclerosis in Israel: Prevalence among immigrants and native inhabitants. Arch Neurol 1962 ; 7 : 253-63.
    • (1962) Arch Neurol , vol.7 , pp. 253-263
    • Alter, M.1    Hapern, L.2    Kurland, L.T.3
  • 3
    • 0013950284 scopus 로고
    • Risk of multiple sclerosis related to age of immigration to Israel
    • Alter M, Leibowitz U, Speer J. Risk of multiple sclerosis related to age of immigration to Israel. Arch Neurol 1966 ; 15 : 234-7.
    • (1966) Arch Neurol , vol.15 , pp. 234-237
    • Alter, M.1    Leibowitz, U.2    Speer, J.3
  • 4
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • Anderson S, Bankier AT, Barell BG, et al. Sequence and organization of the human mitochondrial genome. Nature 1981 ; 290 : 457-64.
    • (1981) Nature , vol.290 , pp. 457-464
    • Anderson, S.1    Bankier, A.T.2    Barell, B.G.3
  • 5
    • 0027235992 scopus 로고
    • Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175 kb region of the TCR Vβ-chain locus and HLA class II genes
    • Beall SS, Biddison WE, McFarlin DE, et al. Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175 kb region of the TCR Vβ-chain locus and HLA class II genes. J Neuroimmunol 1993 ; 45 : 53-60.
    • (1993) J Neuroimmunol , vol.45 , pp. 53-60
    • Beall, S.S.1    Biddison, W.E.2    McFarlin, D.E.3
  • 6
    • 0024592009 scopus 로고
    • The germline repertoire of T-cell receptor β-chain genes in patients with chronic progressive multiple sclerosis
    • Beall SS, Concannon P, Charmley P, et al. The germline repertoire of T-cell receptor β-chain genes in patients with chronic progressive multiple sclerosis. J Neuroimmunol 1989 ; 21 : 59-66.
    • (1989) J Neuroimmunol , vol.21 , pp. 59-66
    • Beall, S.S.1    Concannon, P.2    Charmley, P.3
  • 7
    • 0029009385 scopus 로고
    • The relationship of TAP1 and TAP2 dimorphisms to multiple sclerosis susceptibility
    • Bell RB, Ramachandran S. The relationship of TAP1 and TAP2 dimorphisms to multiple sclerosis susceptibility. J Neuroimmunol 1995 ; 59 : 201-4.
    • (1995) J Neuroimmunol , vol.59 , pp. 201-204
    • Bell, R.B.1    Ramachandran, S.2
  • 8
    • 0029039786 scopus 로고
    • TAP2 polymorphisms in Australian multiple sclerosis patients
    • Bennetts BH, Teutsch SM, Heard RN, et al. TAP2 polymorphisms in Australian multiple sclerosis patients. J Neuroimmunol 1995 ; 59 ; 113-21.
    • (1995) J Neuroimmunol , vol.59 , pp. 113-121
    • Bennetts, B.H.1    Teutsch, S.M.2    Heard, R.N.3
  • 9
    • 0017851427 scopus 로고
    • Twin study of multiple sclerosis. An epidemiologic inquiry
    • Bobowick AR, Kurtzke JF, Brody JF, et al. Twin study of multiple sclerosis. An epidemiologic inquiry. Neurology 1978 ; 28 : 978-87.
    • (1978) Neurology , vol.28 , pp. 978-987
    • Bobowick, A.R.1    Kurtzke, J.F.2    Brody, J.F.3
  • 10
    • 0025317768 scopus 로고
    • DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis
    • Boylan KB, Takahashi N, Paty DW et al. DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis. Ann Neurol 1990 ; 27 : 291-7.
    • (1990) Ann Neurol , vol.27 , pp. 291-297
    • Boylan, K.B.1    Takahashi, N.2    Paty, D.W.3
  • 11
    • 0030572673 scopus 로고    scopus 로고
    • Gene polymorphism at position-308 of the tumor necrosis factor alpha (TNFα) in multiple sclerosis and its influence on the regulation of TNFα production
    • Braun N, Michel U, Ernst BP, et al. Gene polymorphism at position-308 of the tumor necrosis factor alpha (TNFα) in multiple sclerosis and its influence on the regulation of TNFα production. Neurosci Lett 1996 ; 215 : 75-8.
    • (1996) Neurosci Lett , vol.215 , pp. 75-78
    • Braun, N.1    Michel, U.2    Ernst, B.P.3
  • 12
    • 0031034482 scopus 로고    scopus 로고
    • Clustering of Caucasian Leber hereditary optic neuropathy patients containing the 11,778 or 14,484 mutations on an mtDNA lineage
    • Brown MD, Sun F, Wallace DC. Clustering of Caucasian Leber hereditary optic neuropathy patients containing the 11,778 or 14,484 mutations on an mtDNA lineage. Am J Hum Genet 1997 ; 60 : 381-7.
    • (1997) Am J Hum Genet , vol.60 , pp. 381-387
    • Brown, M.D.1    Sun, F.2    Wallace, D.C.3
  • 13
    • 0003006753 scopus 로고
    • The geography of multiple sclerosis reflects genetic susceptibility
    • Bulman DE, Ebers GC. The geography of multiple sclerosis reflects genetic susceptibility. J Trop Geograph Neurol 1992 ; 2 : 66-72.
    • (1992) J Trop Geograph Neurol , vol.2 , pp. 66-72
    • Bulman, D.E.1    Ebers, G.C.2
  • 15
    • 0029014947 scopus 로고
    • Sequence of the human homologue of a mitochondrially encoded murine transplantation antigen in patients with multiple sclerosis
    • Chalmers RM, Robertson N, Kellar-Wood H, Compston DAS, Harding AE. Sequence of the human homologue of a mitochondrially encoded murine transplantation antigen in patients with multiple sclerosis. J Neurol 1995 ; 242 : 332-4.
    • (1995) J Neurol , vol.242 , pp. 332-334
    • Chalmers, R.M.1    Robertson, N.2    Kellar-Wood, H.3    Compston, D.A.S.4    Harding, A.E.5
  • 16
    • 17444436401 scopus 로고    scopus 로고
    • The genetics of multiple sclerosis: Principles, background and updated results of the United Kingdom systematic genome screen
    • Chataway J, Feakes R, Coraddu F, et al. The genetics of multiple sclerosis: Principles, background and updated results of the United Kingdom systematic genome screen. Brain 1998 ; 121 : 1869-87.
    • (1998) Brain , vol.121 , pp. 1869-1887
    • Chataway, J.1    Feakes, R.2    Coraddu, F.3
  • 17
    • 0026948591 scopus 로고
    • Tumor necrosis factor a production as a possible predictor of relapse in patients with multiple sclerosis
    • Chofflon M, Juillard C, Juillard P, et al. Tumor necrosis factor a production as a possible predictor of relapse in patients with multiple sclerosis. Eur Cytokine Netw 1992 ; 3 : 523-31.
    • (1992) Eur Cytokine Netw , vol.3 , pp. 523-531
    • Chofflon, M.1    Juillard, C.2    Juillard, P.3
  • 18
    • 0026454518 scopus 로고
    • Restriction fragment length polymorphism analysis of HLA-DR- and DQ-linked alleles in multiple sclerosis in Spain
    • Clerici N, Fernandez M. Restriction fragment length polymorphism analysis of HLA-DR- and DQ-linked alleles in multiple sclerosis in Spain. J Neuroimmunol 1992 ; 41 : 245-8.
    • (1992) J Neuroimmunol , vol.41 , pp. 245-248
    • Clerici, N.1    Fernandez, M.2
  • 19
    • 0003082857 scopus 로고    scopus 로고
    • Genetic factors in the aetiology of multiple sclerosis
    • McDonald WI, Silberberg DH, eds. Toronto: Butterworths; 19XX
    • Compston A. Genetic factors in the aetiology of multiple sclerosis. In: McDonald WI, Silberberg DH, eds. Multiple Sclerosis. Toronto: Butterworths; 19XX. p. 56-73.
    • Multiple Sclerosis , pp. 56-73
    • Compston, A.1
  • 20
    • 0026049670 scopus 로고
    • HLA-DR and -DQ allelic sequences in multiple sclerosis patients are identical to those found in the general population
    • Cowan EP, Pierce ML, McFarland HF, McFarlin DE. HLA-DR and -DQ allelic sequences in multiple sclerosis patients are identical to those found in the general population. Hum Immunol 1991 ; 32 : 203-10.
    • (1991) Hum Immunol , vol.32 , pp. 203-210
    • Cowan, E.P.1    Pierce, M.L.2    McFarland, H.F.3    McFarlin, D.E.4
  • 21
    • 0029145466 scopus 로고
    • Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis
    • Crusius JBA, Pena AS, van Osten BW, et al. Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis. Lancet 1995 ; 346 : 979.
    • (1995) Lancet , vol.346 , pp. 979
    • Crusius, J.B.A.1    Pena, A.S.2    Van Osten, B.W.3
  • 23
    • 51849180305 scopus 로고
    • Multiple sklerose und erbanlage II. Z.ges
    • Curtius F, Speer H. Multiple sklerose und erbanlage II. Z.ges. Neurol Psychiat 1937 ; 160 : 226-45.
    • (1937) Neurol Psychiat , vol.160 , pp. 226-245
    • Curtius, F.1    Speer, H.2
  • 24
    • 0001882253 scopus 로고
    • Multiple sclerosis from the standpoint of geographic distribution and race
    • Davenport CB. Multiple sclerosis from the standpoint of geographic distribution and race. Arch Neurol 1922 ; 8 : 51-8.
    • (1922) Arch Neurol , vol.8 , pp. 51-58
    • Davenport, C.B.1
  • 25
    • 0014209372 scopus 로고
    • Annual incidence, prevalence and mortality of multiple sclerosis in white South African born and in white immigrants to South Africa
    • Dean G. Annual incidence, prevalence and mortality of multiple sclerosis in white South African born and in white immigrants to South Africa. Br Med J 1967 ; 2 : 724-30.
    • (1967) Br Med J , vol.2 , pp. 724-730
    • Dean, G.1
  • 26
    • 0027339942 scopus 로고
    • HLA-DPB1 alleles correlate with risk for multiple sclerosis in Caucasoid and Cantonese patients lacking the high-risk DQB1 *0601 allele
    • Dekker JW, Easteal S, Jakobsen IB, et al. HLA-DPB1 alleles correlate with risk for multiple sclerosis in Caucasoid and Cantonese patients lacking the high-risk DQB1 *0601 allele. Tissue Antigens 1993 ; 41 : 31-6.
    • (1993) Tissue Antigens , vol.41 , pp. 31-36
    • Dekker, J.W.1    Easteal, S.2    Jakobsen, I.B.3
  • 27
    • 0025089312 scopus 로고
    • Multiple sclerosis in sibling pairs: Clustered onset and familial predisposition
    • Doolittle TH, Myers RH, Lehrich JR et al. Multiple sclerosis in sibling pairs: Clustered onset and familial predisposition. Neurology 1990 ; 40 : 1546-52.
    • (1990) Neurology , vol.40 , pp. 1546-1552
    • Doolittle, T.H.1    Myers, R.H.2    Lehrich, J.R.3
  • 28
    • 0020800552 scopus 로고
    • Genetic factors in multiple sclerosis
    • Ebers GC. Genetic factors in multiple sclerosis. Neurol Clin 1983 ; 1 : 645-54.
    • (1983) Neurol Clin , vol.1 , pp. 645-654
    • Ebers, G.C.1
  • 29
    • 0010502309 scopus 로고    scopus 로고
    • Multiple sclerosis and other demyelinating diseases
    • Asbury A, McKahnn G, McDonald I, eds. Philadelphia: WB Saunders Company; 19XX
    • Ebers GC. Multiple sclerosis and other demyelinating diseases. In: Asbury A, McKahnn G, McDonald I, eds. Diseases of the Nervous System. Philadelphia: WB Saunders Company; 19XX. p. 1268-81.
    • Diseases of the Nervous System , pp. 1268-1281
    • Ebers, G.C.1
  • 30
    • 0022868088 scopus 로고
    • A population-based twin study in multiple sclerosis
    • Ebers GC, Bulman DE, Sadovnick AD, et al. A population-based twin study in multiple sclerosis. N Eng J Med 1986 ; 315 : 1638-42.
    • (1986) N Eng J Med , vol.315 , pp. 1638-1642
    • Ebers, G.C.1    Bulman, D.E.2    Sadovnick, A.D.3
  • 31
    • 15844366743 scopus 로고    scopus 로고
    • A full genome search in multiple sclerosis
    • Ebers GC, Kukay K, Bulman DE, et al. A full genome search in multiple sclerosis. Nature Genet 1996 ; 13 : 472-6.
    • (1996) Nature Genet , vol.13 , pp. 472-476
    • Ebers, G.C.1    Kukay, K.2    Bulman, D.E.3
  • 32
    • 0019954493 scopus 로고
    • HLA typing in multiple sclerosis sibling pairs
    • Ebers GC, Paty DW, Stiller CR, et al. HLA typing in multiple sclerosis sibling pairs. Lancet 1982 ; i : 88-90.
    • (1982) Lancet , vol.1 , pp. 88-90
    • Ebers, G.C.1    Paty, D.W.2    Stiller, C.R.3
  • 33
    • 0027985358 scopus 로고
    • The role of genetic factors in multiple sclerosis susceptibility
    • Ebers GC, Sadovnick AD. The role of genetic factors in multiple sclerosis susceptibility. J Neuroimmunol 1994 ; 54 : 1-17.
    • (1994) J Neuroimmunol , vol.54 , pp. 1-17
    • Ebers, G.C.1    Sadovnick, A.D.2
  • 34
    • 0029121088 scopus 로고
    • A genetic basis for familial aggregation in multiple sclerosis
    • Ebers GC, Sadovnick AD, Risch NJ, et al. A genetic basis for familial aggregation in multiple sclerosis. Nature 1995 ; 377 : 150-1.
    • (1995) Nature , vol.377 , pp. 150-151
    • Ebers, G.C.1    Sadovnick, A.D.2    Risch, N.J.3
  • 35
    • 34447615420 scopus 로고
    • Uber infantile und hereditare multiple Sklerose
    • Eichhorst H. Uber infantile und hereditare multiple Sklerose. Virchows Arch Path Anat 1896 ; 146 : 173-92.
    • (1896) Virchows Arch Path Anat , vol.146 , pp. 173-192
    • Eichhorst, H.1
  • 36
    • 0023357004 scopus 로고
    • HLA association with multiple sclerosis in Sicily and Malta
    • Elian M, Alonso A, Awad J, et al. HLA association with multiple sclerosis in Sicily and Malta. Dis Markers 1987 ; 5 : 89-99.
    • (1987) Dis Markers , vol.5 , pp. 89-99
    • Elian, M.1    Alonso, A.2    Awad, J.3
  • 37
    • 0025129723 scopus 로고
    • Multiple sclerosis among the United Kingdom born children of immigrants from the Indian subcontinent, Africa and the West Indies
    • Elian M, Nightingale S, Dean G. Multiple sclerosis among the United Kingdom born children of immigrants from the Indian subcontinent, Africa and the West Indies. J Neurol Neurosurg Psychiatry 1990 ; 53 : 906-11.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 906-911
    • Elian, M.1    Nightingale, S.2    Dean, G.3
  • 38
    • 0017839794 scopus 로고
    • Multiple sclerosis among Spanish surnamed Californians
    • Enstrom JE, Operskalski EA. Multiple sclerosis among Spanish surnamed Californians. Neurology 1978 ; 28 : 434-8.
    • (1978) Neurology , vol.28 , pp. 434-438
    • Enstrom, J.E.1    Operskalski, E.A.2
  • 39
    • 0028810117 scopus 로고
    • Evidence of linkage between susceptibility to multiple sclerosis and HLA class II loci in Italian multiplex families
    • Eoli M, Pandolfo M, Amoroso A, et al. Evidence of linkage between susceptibility to multiple sclerosis and HLA class II loci in Italian multiplex families. Eur J Hum Genet 1995 ; 3 : 303-11.
    • (1995) Eur J Hum Genet , vol.3 , pp. 303-311
    • Eoli, M.1    Pandolfo, M.2    Amoroso, A.3
  • 40
    • 1842410720 scopus 로고    scopus 로고
    • Genetic predisposition to multiple sclerosis as revealed by immunoprinting
    • Epplen C, Jackel S, Eduardo JM, et al. Genetic predisposition to multiple sclerosis as revealed by immunoprinting. Ann Neurol 1997 ; 41 : 341-52.
    • (1997) Ann Neurol , vol.41 , pp. 341-352
    • Epplen, C.1    Jackel, S.2    Eduardo, J.M.3
  • 41
    • 0031737082 scopus 로고    scopus 로고
    • Susceptibility to multiple sclerosis and the immunoglobulin heavy chain gene cluster
    • Feakes R, Chataway J, Sawcer S, et al. Susceptibility to multiple sclerosis and the immunoglobulin heavy chain gene cluster Ann Neurol 1998 ; 44 : 984.
    • (1998) Ann Neurol , vol.44 , pp. 984
    • Feakes, R.1    Chataway, J.2    Sawcer, S.3
  • 42
    • 0027731794 scopus 로고
    • Association of the 11,778 mitochondrial DNA mutation and demyelinating disease
    • Flanigan KM, Johns DR. Association of the 11,778 mitochondrial DNA mutation and demyelinating disease. Neurology 1993 ; 43 : 2720-2.
    • (1993) Neurology , vol.43 , pp. 2720-2722
    • Flanigan, K.M.1    Johns, D.R.2
  • 43
    • 0028982538 scopus 로고
    • The multiple sclerosis and narcolepsy-associated HLA class II haplotype includes the DRB5*0101 allele
    • Fogdell A, Hillert J, Sachs C, et al. The multiple sclerosis and narcolepsy-associated HLA class II haplotype includes the DRB5*0101 allele. Tissue Antigens 1995 ; 46 : 333-6.
    • (1995) Tissue Antigens , vol.46 , pp. 333-336
    • Fogdell, A.1    Hillert, J.2    Sachs, C.3
  • 44
    • 0030935570 scopus 로고    scopus 로고
    • Linkage analysis of HLA class II genes in Swedish multiplex families with multiplex sclerosis
    • Fogdell A, Olerup O, Fredrikson S, et al. Linkage analysis of HLA class II genes in Swedish multiplex families with multiplex sclerosis. Neurology 1997 ; 48 : 758-62.
    • (1997) Neurology , vol.48 , pp. 758-762
    • Fogdell, A.1    Olerup, O.2    Fredrikson, S.3
  • 45
    • 0023114458 scopus 로고
    • Multiple sclerosis in north-east Scotland. An association with HLA-DQw1
    • Francis DA, Batchelor JR, McDonald WI, et al. Multiple sclerosis in north-east Scotland. An association with HLA-DQw1. Brain 1987 ; 110 : 181-96.
    • (1987) Brain , vol.110 , pp. 181-196
    • Francis, D.A.1    Batchelor, J.R.2    McDonald, W.I.3
  • 47
    • 0026091158 scopus 로고
    • Multiple sclerosis and HLA: Is the susceptibility gene really HLA-DR or HLA-DQ?
    • Francis DA, Thompson AJ, Brookes P, et al. Multiple sclerosis and HLA: Is the susceptibility gene really HLA-DR or HLA-DQ? Hum Immunol 1991 ; 32 : 119-24.
    • (1991) Hum Immunol , vol.32 , pp. 119-124
    • Francis, D.A.1    Thompson, A.J.2    Brookes, P.3
  • 48
    • 0026772532 scopus 로고
    • Conjugal multiple sclerosis: Immunogenetic characterization and analysis of T-and B-cell reactivity to myelin proteins
    • Fredrikson S, Michelsberg J, Hillert J, et al. Conjugal multiple sclerosis: Immunogenetic characterization and analysis of T-and B-cell reactivity to myelin proteins. Neurology 1992 ; 42 : 577-82.
    • (1992) Neurology , vol.42 , pp. 577-582
    • Fredrikson, S.1    Michelsberg, J.2    Hillert, J.3
  • 49
    • 0026497413 scopus 로고
    • Multiple Sclerosis in 54 twinship: Concordance rate is independent of zygosity
    • French Research Group on Multiple Sclerosis. Multiple Sclerosis in 54 twinship: Concordance rate is independent of zygosity. Ann Neurol 1992 ; 32 : 724-7.
    • (1992) Ann Neurol , vol.32 , pp. 724-727
  • 50
    • 0025329622 scopus 로고
    • The germline repertoire of T-cell receptor β-chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis
    • Fugger L, Sandberg-Wollheim M, Morling N, et al. The germline repertoire of T-cell receptor β-chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis. Immunogenet 1990 ; 31 : 178-80.
    • (1990) Immunogenet , vol.31 , pp. 178-180
    • Fugger, L.1    Sandberg-Wollheim, M.2    Morling, N.3
  • 51
    • 0030587583 scopus 로고    scopus 로고
    • Tumor Necrosis Factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion
    • Garcia-Merino A, Alper CA, Usuku K, et al. Tumor Necrosis Factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion. Hum Immunol 1996 ; 50 : 11-21.
    • (1996) Hum Immunol , vol.50 , pp. 11-21
    • Garcia-Merino, A.1    Alper, C.A.2    Usuku, K.3
  • 52
    • 0029037577 scopus 로고
    • Importance of HLA-DRB1 and DQA1 genes and of the amino acid polymorphisms in the functional domain of DRβ1-chain in multiple sclerosis
    • Ghabanbasani MZ, Gu XX, Spaepen M, et al. Importance of HLA-DRB1 and DQA1 genes and of the amino acid polymorphisms in the functional domain of DRβ1-chain in multiple sclerosis. J Neuroimmunol 1995 ; 59 : 77-82.
    • (1995) J Neuroimmunol , vol.59 , pp. 77-82
    • Ghabanbasani, M.Z.1    Gu, X.X.2    Spaepen, M.3
  • 53
    • 0022504170 scopus 로고
    • Immunogenetic profile of multiple sclerosis in Mexicans
    • Gorodezky C, Najera R, Rangel BE, et al. Immunogenetic profile of multiple sclerosis in Mexicans. Hum Immunol 1986 ; 6 : 364-74.
    • (1986) Hum Immunol , vol.6 , pp. 364-374
    • Gorodezky, C.1    Najera, R.2    Rangel, B.E.3
  • 54
    • 0022360744 scopus 로고
    • Multiple sclerosis in the two northernmost counties of Norway
    • Gronning M, Mellgren SI. Multiple sclerosis in the two northernmost counties of Norway. Acta Neurol Scand 1985 ; 72 : 321-7.
    • (1985) Acta Neurol Scand , vol.72 , pp. 321-327
    • Gronning, M.1    Mellgren, S.I.2
  • 55
    • 0019410424 scopus 로고
    • The HLA antigen distribution in a gypsy population in Hungary
    • Gyodi E, Tauszik T, Petranyi G, et al. The HLA antigen distribution in a gypsy population in Hungary. Tissue Antigen 1981 ; 18 : 1-12.
    • (1981) Tissue Antigen , vol.18 , pp. 1-12
    • Gyodi, E.1    Tauszik, T.2    Petranyi, G.3
  • 56
    • 0026712402 scopus 로고
    • Contribution of a single DQ β-chain residue to multiple sclerosis in French Canadians
    • Haegert DG, Francis GS. Contribution of a single DQ β-chain residue to multiple sclerosis in French Canadians. Hum Immunol 1992 ; 34 : 85-90.
    • (1992) Hum Immunol , vol.34 , pp. 85-90
    • Haegert, D.G.1    Francis, G.S.2
  • 57
    • 0027159240 scopus 로고
    • HLA-DQ polymorphisms do not explain HLA class II associations with multiple sclerosis in two Canadian patient groups
    • Haegert DG, Francis GS. HLA-DQ polymorphisms do not explain HLA class II associations with multiple sclerosis in two Canadian patient groups. Neurology 1993 ; 43 : 1207-10.
    • (1993) Neurology , vol.43 , pp. 1207-1210
    • Haegert, D.G.1    Francis, G.S.2
  • 58
    • 0024383372 scopus 로고
    • HLA-DR β, DQ α and DQ β restriction fragment length polymorphisms in multiple sclerosis
    • Haegert DG, Michaud M, Schwab C, et al. HLA-DR β, DQ α and DQ β restriction fragment length polymorphisms in multiple sclerosis. J Neurosci Res 1989 ; 23 : 46-54.
    • (1989) J Neurosci Res , vol.23 , pp. 46-54
    • Haegert, D.G.1    Michaud, M.2    Schwab, C.3
  • 59
    • 85089317675 scopus 로고    scopus 로고
    • Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland
    • Haegert DG, Swift FV, Benedikz J. Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland. Neurology 1996 ; 46 : 1107-11.
    • (1996) Neurology , vol.46 , pp. 1107-1111
    • Haegert, D.G.1    Swift, F.V.2    Benedikz, J.3
  • 60
    • 7344223861 scopus 로고    scopus 로고
    • Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity
    • Haines JL, Terwedow HA, Burgess K, et al. Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. Hum Mol Genet 1998 ; 7 : 1229-34.
    • (1998) Hum Mol Genet , vol.7 , pp. 1229-1234
    • Haines, J.L.1    Terwedow, H.A.2    Burgess, K.3
  • 61
    • 0028595987 scopus 로고
    • Leber's hereditary optic neuropathy mitochondrial DNA mutations in childhood multiple sclerosis
    • Hanefeld FA, Ernst BP, Wilichowski E, Cristen HJ. Leber's hereditary optic neuropathy mitochondrial DNA mutations in childhood multiple sclerosis. Neuropediatrics 1994 ; 25 : 331.
    • (1994) Neuropediatrics , vol.25 , pp. 331
    • Hanefeld, F.A.1    Ernst, B.P.2    Wilichowski, E.3    Cristen, H.J.4
  • 62
    • 0026782507 scopus 로고
    • Occurrence of multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation
    • Harding AE, Sweeney MG, Miller DH, et al. Occurrence of multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation. Brain 1992 ; 115 : 979-89.
    • (1992) Brain , vol.115 , pp. 979-989
    • Harding, A.E.1    Sweeney, M.G.2    Miller, D.H.3
  • 63
    • 0026774406 scopus 로고
    • T-cell receptor α-chain polymorphism in multiple sclerosis
    • Hashimoto LL, Mak TW, Ebers GC. T-cell receptor α-chain polymorphism in multiple sclerosis. J Neuroimmunol 1992 ; 40 : 41-8.
    • (1992) J Neuroimmunol , vol.40 , pp. 41-48
    • Hashimoto, L.L.1    Mak, T.W.2    Ebers, G.C.3
  • 64
    • 0027252104 scopus 로고
    • Immunoglobulin heavy chain variable region polymorphisms and multiple sclerosis susceptibility
    • Hashimoto LL, Walter MA, Cox DW, Ebers GC. Immunoglobulin heavy chain variable region polymorphisms and multiple sclerosis susceptibility. J Neuroimmunol 1993 ; 47 : 77-84.
    • (1993) J Neuroimmunol , vol.47 , pp. 77-84
    • Hashimoto, L.L.1    Walter, MA.2    Cox, D.W.3    Ebers, G.C.4
  • 65
    • 0024533562 scopus 로고
    • Extended major histocompatibility complex haplotypes in patients with multiple sclerosis
    • Hauser SL, Fleischnick E, Weiner HL, et al. Extended major histocompatibility complex haplotypes in patients with multiple sclerosis. Neurology 1989 ; 39 : 275-7.
    • (1989) Neurology , vol.39 , pp. 275-277
    • Hauser, S.L.1    Fleischnick, E.2    Weiner, H.L.3
  • 66
    • 0023894731 scopus 로고
    • No apparent association between HLA and multiple sclerosis in southern Chinese
    • Hawkins BR, Yu YL, Huang CY. No apparent association between HLA and multiple sclerosis in southern Chinese. J Neurol Neurosurg Psychiatry 1988 ; 51 : 443-5.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 443-445
    • Hawkins, B.R.1    Yu, Y.L.2    Huang, C.Y.3
  • 68
    • 0029563072 scopus 로고
    • Tumor necrosis factor alpha 308 alleles in multiple sclerosis
    • He B, Navikas V, Lundahl J, et al. Tumor necrosis factor alpha 308 alleles in multiple sclerosis. J Neuroimmunol 1995 ; 63 : 143-7.
    • (1995) J Neuroimmunol , vol.63 , pp. 143-147
    • He, B.1    Navikas, V.2    Lundahl, J.3
  • 69
    • 0032100761 scopus 로고    scopus 로고
    • Linkage and association analysis of genes encoding cytokines and myelin proteins in multiple sclerosis
    • He B, Xu C, Yang B, et al. Linkage and association analysis of genes encoding cytokines and myelin proteins in multiple sclerosis. J Neuroimmunol 1998 ; 86 : 13-9.
    • (1998) J Neuroimmunol , vol.86 , pp. 13-19
    • He, B.1    Xu, C.2    Yang, B.3
  • 70
    • 0031964047 scopus 로고    scopus 로고
    • The myelin basic protein gene in multiple sclerosis: Identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence
    • He B, Yang B. Lundahl J, et al. The myelin basic protein gene in multiple sclerosis: Identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence. Acta Neurol Scand 1998 ; 97 : 46-51.
    • (1998) Acta Neurol Scand , vol.97 , pp. 46-51
    • He, B.1    Yang, B.2    Lundahl, J.3
  • 71
    • 0020477385 scopus 로고
    • Concordance in twins and recurrence in sibship in multiple sclerosis
    • Heltberg A, Holm NV. Concordance in twins and recurrence in sibship in multiple sclerosis. Lancet 1982 ; i : 1068.
    • (1982) Lancet , vol.1 , pp. 1068
    • Heltberg, A.1    Holm, N.V.2
  • 72
    • 0028227135 scopus 로고
    • Human leukocyte antigen studies in multiple sclerosis
    • Hillert J. Human leukocyte antigen studies in multiple sclerosis. Ann Neurol 1994 ; 36 Suppl : S15-17.
    • (1994) Ann Neurol , vol.36 , Issue.SUPPL.
    • Hillert, J.1
  • 73
    • 0027474075 scopus 로고
    • Immunoglobulin constant region gene polymorphism in multiple sclerosis
    • Hillert J. Immunoglobulin constant region gene polymorphism in multiple sclerosis. J Neuroimmunol 1993 ; 43 : 9-14.
    • (1993) J Neuroimmunol , vol.43 , pp. 9-14
    • Hillert, J.1
  • 74
    • 0028153827 scopus 로고
    • The HLA-Dw2 haplotype segregates closely with multiple sclerosis in multiplex families
    • Hillert J, Kall T, Vrethem M, et al. The HLA-Dw2 haplotype segregates closely with multiple sclerosis in multiplex families. J Neuroimmunol 1994 ; 50 : 95-100.
    • (1994) J Neuroimmunol , vol.50 , pp. 95-100
    • Hillert, J.1    Kall, T.2    Vrethem, M.3
  • 75
    • 0025907869 scopus 로고
    • No association with germline T-cell receptor β-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis
    • Hillert J, Leng C, Olerup O. No association with germline T-cell receptor β-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis. J Neuroimmunol 1991 ; 32 : 141-7.
    • (1991) J Neuroimmunol , vol.32 , pp. 141-147
    • Hillert, J.1    Leng, C.2    Olerup, O.3
  • 76
    • 0027492226 scopus 로고
    • Multiple sclerosis is associated with genes within and close to the HLA-DR-DQ subregion on a normal DR15,DQ6,Dw2 haplotype
    • Hillert J, Olerup O. Multiple sclerosis is associated with genes within and close to the HLA-DR-DQ subregion on a normal DR15,DQ6,Dw2 haplotype. Neurology 1993 ; 43 : 163-8.
    • (1993) Neurology , vol.43 , pp. 163-168
    • Hillert, J.1    Olerup, O.2
  • 77
    • 0031911063 scopus 로고    scopus 로고
    • Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of TCR β locus: Use of effected family-based controls
    • Hockertz MK, Paty DW, Beall SS. Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of TCR β locus: Use of effected family-based controls. Am J Hum Genet 1998 ; 62 : 373-85.
    • (1998) Am J Hum Genet , vol.62 , pp. 373-385
    • Hockertz, M.K.1    Paty, D.W.2    Beall, S.S.3
  • 78
    • 0025780303 scopus 로고
    • No association between susceptibility to multiple sclerosis and HLA-DPB1 alleles in the French Canadian population
    • Howell WM, Sage DA, Evans PR, et al. No association between susceptibility to multiple sclerosis and HLA-DPB1 alleles in the French Canadian population. Tissue Antigens 1991 ; 37 : 156-60.
    • (1991) Tissue Antigens , vol.37 , pp. 156-160
    • Howell, W.M.1    Sage, D.A.2    Evans, P.R.3
  • 79
    • 0015733713 scopus 로고
    • Histocompatibility determinants of multiple sclerosis, with special reference to clinical course
    • Jersild C, Fog T, Hansen GS, et al. Histocompatibility determinants of multiple sclerosis, with special reference to clinical course. Lancet 1973 ; ii : 1221-5.
    • (1973) Lancet , vol.2 , pp. 1221-1225
    • Jersild, C.1    Fog, T.2    Hansen, G.S.3
  • 80
    • 0027495346 scopus 로고
    • Multiple sclerosis in the Faro Islands. VI. Studies of HLA markers
    • Jershild C, Kurtzke JF, Riisom K, et al. Multiple sclerosis in the Faro Islands. VI. Studies of HLA markers. Tissue Antigens 1993 ; 42 : 105-10.
    • (1993) Tissue Antigens , vol.42 , pp. 105-110
    • Jershild, C.1    Kurtzke, J.F.2    Riisom, K.3
  • 81
    • 0031656952 scopus 로고    scopus 로고
    • Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis?
    • Kalman B, Alder H. Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis? Acta Neurol Scand 1998 ; 98 : 232-7.
    • (1998) Acta Neurol Scand , vol.98 , pp. 232-237
    • Kalman, B.1    Alder, H.2
  • 82
    • 0032897253 scopus 로고    scopus 로고
    • Large screening of the mitochondrial DNA reveals no pathogenic or polymorphic mutations but a haplotype associated with multiple sclerosis in Caucasians
    • Kalman B, Li S, Chatterjee D, O'Connor D, Voehl MR, Brown MD, et al. Large screening of the mitochondrial DNA reveals no pathogenic or polymorphic mutations but a haplotype associated with multiple sclerosis in Caucasians. Acta Neurol Scand 1999 ; 99 : 16-25.
    • (1999) Acta Neurol Scand , vol.99 , pp. 16-25
    • Kalman, B.1    Li, S.2    Chatterjee, D.3    O'Connor, D.4    Voehl, M.R.5    Brown, M.D.6
  • 83
    • 0029279163 scopus 로고
    • Mitochondrial DNA mutations in multiple sclerosis
    • Kalman B, Lublin FD, Alder H. Mitochondrial DNA mutations in multiple sclerosis. Multiple Sclerosis 1995 ; 1 : 32-6.
    • (1995) Multiple Sclerosis , vol.1 , pp. 32-36
    • Kalman, B.1    Lublin, F.D.2    Alder, H.3
  • 84
    • 0030247011 scopus 로고    scopus 로고
    • Characterization of the mitochondrial DNA in multiple sclerosis
    • Kalman B, Lublin FD, Alder H. Characterization of the mitochondrial DNA in multiple sclerosis. J Neurol Sci 1996 ; 140 : 75-89.
    • (1996) J Neurol Sci , vol.140 , pp. 75-89
    • Kalman, B.1    Lublin, F.D.2    Alder, H.3
  • 85
    • 0030640474 scopus 로고    scopus 로고
    • Screening for Leber's hereditary optic neuropathy associated mitochondrial DNA mutations in patients with prominent optic neuritis
    • Kalman B, Rodriguez-Valdez JL, Bosch U, Lublin FD. Screening for Leber's hereditary optic neuropathy associated mitochondrial DNA mutations in patients with prominent optic neuritis. Multiple Sclerosis 1997 ; 2 : 279-82.
    • (1997) Multiple Sclerosis , vol.2 , pp. 279-282
    • Kalman, B.1    Rodriguez-Valdez, J.L.2    Bosch, U.3    Lublin, F.D.4
  • 87
  • 88
    • 0029072687 scopus 로고
    • Multiple sclerosis and the HLA D region: Linkage and association studies
    • Kellar-Wood HF, Wood NW, Holmans P, et al. Multiple sclerosis and the HLA D region: Linkage and association studies. J Neuroimmunol 1995 ; 58 : 183-90.
    • (1995) J Neuroimmunol , vol.58 , pp. 183-190
    • Kellar-Wood, H.F.1    Wood, N.W.2    Holmans, P.3
  • 89
    • 0023731175 scopus 로고
    • Genetic susceptibility to multiple sclerosis: A co-twin study of a nationwide series
    • Kinnunen E, Juntunen J, Ketonen L, et al. Genetic susceptibility to multiple sclerosis: A co-twin study of a nationwide series. Arch Neurol 1988 ; 45 : 1108-11.
    • (1988) Arch Neurol , vol.45 , pp. 1108-1111
    • Kinnunen, E.1    Juntunen, J.2    Ketonen, L.3
  • 90
    • 0021229786 scopus 로고
    • Histocompatibility antigens in familial multiple sclerosis in a high-risk area of the disease
    • Kinnunen E. Koskimies S, Lagerstedt A, Wikstrom J. Histocompatibility antigens in familial multiple sclerosis in a high-risk area of the disease. J Neurol Sci 1984 ; 65 : 147-55.
    • (1984) J Neurol Sci , vol.65 , pp. 147-155
    • Kinnunen, E.1    Koskimies, S.2    Lagerstedt, A.3    Wikstrom, J.4
  • 91
    • 0024423248 scopus 로고
    • An epidemiological study of multiple sclerosis
    • Koch-Henriksen N. An epidemiological study of multiple sclerosis. Acta Neurol Scand 1989 ; 124 : 1-123.
    • (1989) Acta Neurol Scand , vol.124 , pp. 1-123
    • Koch-Henriksen, N.1
  • 92
    • 17344367913 scopus 로고    scopus 로고
    • Genome-wide scan of multiple sclerosis in Finnish multiplex families
    • Kuokannen S, Gschwend M, Rioux JD, et al. Genome-wide scan of multiple sclerosis in Finnish multiplex families. Am J Hum Genet 1997 ; 61 : 1379-87.
    • (1997) Am J Hum Genet , vol.61 , pp. 1379-1387
    • Kuokannen, S.1    Gschwend, M.2    Rioux, J.D.3
  • 93
    • 0017626149 scopus 로고
    • Different B-lymphocyte alloantigens associated with multiple sclerosis in Arabs and northern Europeans
    • Kurdi A, Ayesh I, Abdallat A, et al. Different B-lymphocyte alloantigens associated with multiple sclerosis in Arabs and northern Europeans. Lancet 1977 ; i : 1123-5.
    • (1977) Lancet , vol.1 , pp. 1123-1125
    • Kurdi, A.1    Ayesh, I.2    Abdallat, A.3
  • 94
    • 0021023964 scopus 로고
    • Prevalence of multiple sclerosis and its north to south gradient in Japan
    • Kuroiwa Y, Shibasaki H, Ikeda M. Prevalence of multiple sclerosis and its north to south gradient in Japan. Neuroepidemiol 1983 ; 2 : 62-9.
    • (1983) Neuroepidemiol , vol.2 , pp. 62-69
    • Kuroiwa, Y.1    Shibasaki, H.2    Ikeda, M.3
  • 95
    • 0016435596 scopus 로고
    • A reassessment of the distribution of multiple sclerosis. Part one
    • Kurtzke JF. A reassessment of the distribution of multiple sclerosis. Part one. Acta Neurol Scand 1975 ; 51 : 110-36.
    • (1975) Acta Neurol Scand , vol.51 , pp. 110-136
    • Kurtzke, J.F.1
  • 96
    • 0016428403 scopus 로고
    • A reassessment of the distribution of multiple sclerosis. Part two
    • Kurtzke JF. A reassessment of the distribution of multiple sclerosis. Part two. Acta Neurol Scand 1975 ; 51 : 137-57.
    • (1975) Acta Neurol Scand , vol.51 , pp. 137-157
    • Kurtzke, J.F.1
  • 97
    • 0027421126 scopus 로고
    • Epidemiologie evidence for multiple sclerosis as an infection
    • Kurtzke JF. Epidemiologie evidence for multiple sclerosis as an infection. Clin Microbiol Rev 1993 ; 6 : 382-427.
    • (1993) Clin Microbiol Rev , vol.6 , pp. 382-427
    • Kurtzke, J.F.1
  • 98
    • 0018355870 scopus 로고
    • Epidemiology of multiple sclerosis in US veterans, 1. Race, sex and geographic distribution
    • Kurtzke JF, Beebe GW, Norman JE. Epidemiology of multiple sclerosis in US veterans, 1. Race, sex and geographic distribution. Neurology 1979 ; 29 : 1228-35.
    • (1979) Neurology , vol.29 , pp. 1228-1235
    • Kurtzke, J.F.1    Beebe, G.W.2    Norman, J.E.3
  • 99
    • 0016675545 scopus 로고
    • Multiple sclerosis: An epidemic disease in the Faroes
    • Kurtzke J, Hyllested K. Multiple sclerosis: An epidemic disease in the Faroes. Trans Am Neurol Assoc 1975 ; 100 : 213-5.
    • (1975) Trans Am Neurol Assoc , vol.100 , pp. 213-215
    • Kurtzke, J.1    Hyllested, K.2
  • 101
    • 0027155587 scopus 로고
    • Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis
    • Liblau R, van Endert PM, Sandberg-Wollheim M, et al. Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis. Neurology 1993 ; 43 : 1192-7.
    • (1993) Neurology , vol.43 , pp. 1192-1197
    • Liblau, R.1    Van Endert, P.M.2    Sandberg-Wollheim, M.3
  • 102
    • 0002211652 scopus 로고
    • The geographic distribution of multiple sclerosis and its estimated prevalence in the United States
    • Limburg CC. The geographic distribution of multiple sclerosis and its estimated prevalence in the United States. Proc Assoc Res Nerv Ment Dis 1950 ; 28 : 15-24.
    • (1950) Proc Assoc Res Nerv Ment Dis , vol.28 , pp. 15-24
    • Limburg, C.C.1
  • 103
    • 0025364096 scopus 로고
    • The inheritance of MS susceptibility
    • Lord D, O'Fareil AG, Stauton H, et al. The inheritance of MS susceptibility. Ir J Med Sci 1990 ; 159 : 1-20.
    • (1990) Ir J Med Sci , vol.159 , pp. 1-20
    • Lord, D.1    O'Fareil, A.G.2    Stauton, H.3
  • 104
    • 0025986996 scopus 로고
    • Discordance of T-cell receptor β-chain genes in familial multiple sclerosis
    • Lynch SG, Rose JW, Petajan JH, et al. Discordance of T-cell receptor β-chain genes in familial multiple sclerosis. Ann Neurol 1991 ; 30 : 402-10.
    • (1991) Ann Neurol , vol.30 , pp. 402-410
    • Lynch, S.G.1    Rose, J.W.2    Petajan, J.H.3
  • 105
    • 0026609572 scopus 로고
    • Discordance of the T-cell receptor α-chain in familial multiple sclerosis
    • Lynch SG, Rose J, Petajan JH, Leppert M. Discordance of the T-cell receptor α-chain in familial multiple sclerosis. Neurology 1992 ; 42 : 839-44.
    • (1992) Neurology , vol.42 , pp. 839-844
    • Lynch, S.G.1    Rose, J.2    Petajan, J.H.3    Leppert, M.4
  • 106
    • 0013965180 scopus 로고
    • Multiple sclerosis in twins and their relatives. Final report
    • Mackay RP, Myrianthopoulos NC. Multiple sclerosis in twins and their relatives. Final report. Arch Neurol Psych 1966 ; 15 : 449-62.
    • (1966) Arch Neurol Psych , vol.15 , pp. 449-462
    • Mackay, R.P.1    Myrianthopoulos, N.C.2
  • 107
    • 0028803574 scopus 로고
    • Polymorphic tri- and tetranucleotide repeats in exon 1 and 8 of the Myelin Oligodendrocyte Glycoprotein (MOG) gene
    • Malfroy R, Viratelle C, Coppin H, et al. Polymorphic tri- and tetranucleotide repeats in exon 1 and 8 of the Myelin Oligodendrocyte Glycoprotein (MOG) gene. Hum Genet 1995 ; 96 : 737-8.
    • (1995) Hum Genet , vol.96 , pp. 737-738
    • Malfroy, R.1    Viratelle, C.2    Coppin, H.3
  • 108
    • 0022391877 scopus 로고
    • Association of class II HLA-DQ beta chain restriction fragments with multiple sclerosis
    • Marcadet A, Massart C, Semana G, et al. Association of class II HLA-DQ beta chain restriction fragments with multiple sclerosis. Immunogenet 1985 ; 22 : 93-6.
    • (1985) Immunogenet , vol.22 , pp. 93-96
    • Marcadet, A.1    Massart, C.2    Semana, G.3
  • 109
    • 0023727531 scopus 로고
    • Sardinian multiple sclerosis is associated with HLA-DR4: A serologic and molecular analysis
    • Marrosu MG, Muntoni F, Murru MR, et al. Sardinian multiple sclerosis is associated with HLA-DR4: A serologic and molecular analysis. Neurology 1988 ; 38 : 1749-53.
    • (1988) Neurology , vol.38 , pp. 1749-1753
    • Marrosu, M.G.1    Muntoni, F.2    Murru, M.R.3
  • 110
    • 0029759665 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in multiple sclerosis patients with severe optic involvement
    • Mayr-Wohlfart U, Paulus C, Henneberg A, Rodel G. Mitochondrial DNA mutations in multiple sclerosis patients with severe optic involvement. Acta Neurol Scand 1996 ; 94 : 167-71.
    • (1996) Acta Neurol Scand , vol.94 , pp. 167-171
    • Mayr-Wohlfart, U.1    Paulus, C.2    Henneberg, A.3    Rodel, G.4
  • 111
    • 0028008933 scopus 로고
    • Epidemiology of multiple sclerosis in Australia
    • McLeod J, Hammond S, Hallpike J. Epidemiology of multiple sclerosis in Australia. Med J Aust 1994 ; 160 : 117-22.
    • (1994) Med J Aust , vol.160 , pp. 117-122
    • McLeod, J.1    Hammond, S.2    Hallpike, J.3
  • 112
    • 0031722260 scopus 로고    scopus 로고
    • A systemic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS
    • Mertens C, Brassat D, Reboul J, et al. A systemic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS. Neurology 1998 ; 51 : 748-53.
    • (1998) Neurology , vol.51 , pp. 748-753
    • Mertens, C.1    Brassat, D.2    Reboul, J.3
  • 113
    • 0025165910 scopus 로고
    • Multiple sclerosis in Australia and New Zealand: Are the determinants genetic or environmental?
    • Miller D, Hammond S, McLeod J, et al. Multiple sclerosis in Australia and New Zealand: Are the determinants genetic or environmental? J Neurol Neurosurg Psychiatry 1990 ; 53 : 903-5.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 903-905
    • Miller, D.1    Hammond, S.2    McLeod, J.3
  • 114
    • 0028128084 scopus 로고
    • The British Isles survey of multiple sclerosis in twins
    • Mumford CJ, Wood NW, Kellar-Wood H, et al. The British Isles survey of multiple sclerosis in twins. Neurology 1994 ; 44 : 11-5.
    • (1994) Neurology , vol.44 , pp. 11-15
    • Mumford, C.J.1    Wood, N.W.2    Kellar-Wood, H.3
  • 115
    • 0032522204 scopus 로고    scopus 로고
    • Multiple sclerosis: The frequency of allelic forms of tumor necrosis factors and lymphotoxin-alpha
    • Mycko M, Kowalski W, Kwinkowski M, et al. Multiple sclerosis: The frequency of allelic forms of tumor necrosis factors and lymphotoxin-alpha. J Neuroimmunol 1998 ; 84 : 198-206.
    • (1998) J Neuroimmunol , vol.84 , pp. 198-206
    • Mycko, M.1    Kowalski, W.2    Kwinkowski, M.3
  • 116
    • 0031947049 scopus 로고    scopus 로고
    • Multiple Sclerosis: The increased frequency of the ICAM-1 exon 6 gene point mutation genetic type K469
    • Mycko MP, Kwinkowski M, Tronczynska E, et al. Multiple Sclerosis: The increased frequency of the ICAM-1 exon 6 gene point mutation genetic type K469. Ann Neurol 1998 ; 44 : 70-5.
    • (1998) Ann Neurol , vol.44 , pp. 70-75
    • Mycko, M.P.1    Kwinkowski, M.2    Tronczynska, E.3
  • 117
  • 118
    • 0029153643 scopus 로고
    • No association of the 11,778 mitochondrial DNA mutation and multiple sclerosis in Japan
    • Nishimura M, Obayashi H, Ohta M, Uchiyama T, Hao Q, Saida T. No association of the 11,778 mitochondrial DNA mutation and multiple sclerosis in Japan. Neurology 1995 ; 45 : 1333-4.
    • (1995) Neurology , vol.45 , pp. 1333-1334
    • Nishimura, M.1    Obayashi, H.2    Ohta, M.3    Uchiyama, T.4    Hao, Q.5    Saida, T.6
  • 120
    • 0024555653 scopus 로고
    • T-cell receptor Vα and Cαa alleles associated with multiple sclerosis and myasthenia gravis
    • Oksenberg JR, Sherritt M, Begovich AB, et al. T-cell receptor Vα and Cαa alleles associated with multiple sclerosis and myasthenia gravis. Proc Natl Acad Sci 1989 ; 86 : 988-92.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 988-992
    • Oksenberg, J.R.1    Sherritt, M.2    Begovich, A.B.3
  • 122
    • 0025767289 scopus 로고
    • HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation
    • Olerup O, Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation. Tissue Antigens 1991 ; 38 : 1-15.
    • (1991) Tissue Antigens , vol.38 , pp. 1-15
    • Olerup, O.1    Hillert, J.2
  • 123
    • 0024436331 scopus 로고
    • Primary chronic progressive and relapsing/remitting multiple sclerosis: Two immunogenetically distinct disease entities
    • Olerup O, Hillert J, Fredrikson S, et al. Primary chronic progressive and relapsing/remitting multiple sclerosis: Two immunogenetically distinct disease entities. Proc Natl Acad Sci 1989 ; 86 : 7113-7.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 7113-7117
    • Olerup, O.1    Hillert, J.2    Fredrikson, S.3
  • 124
    • 0028957580 scopus 로고
    • Leber's hereditary optic neuropathy associated with a disorder indistinguishable from multiple sclerosis in a male harboring the mitochondrial DNA 11,778 mutation
    • Olsen NK, Hansen AW, Norby S, Edal AL, Jorgensen JR, Rosenberg T. Leber's hereditary optic neuropathy associated with a disorder indistinguishable from multiple sclerosis in a male harboring the mitochondrial DNA 11,778 mutation. Acta Neurol Scand 1995 ; 91 : 326-9.
    • (1995) Acta Neurol Scand , vol.91 , pp. 326-329
    • Olsen, N.K.1    Hansen, A.W.2    Norby, S.3    Edal, A.L.4    Jorgensen, J.R.5    Rosenberg, T.6
  • 125
    • 0019424530 scopus 로고
    • Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis
    • Pandey JP, Goust JM, Salier JP. Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis. J Clin Invest 1981 ; 67 : 1797-800.
    • (1981) J Clin Invest , vol.67 , pp. 1797-1800
    • Pandey, J.P.1    Goust, J.M.2    Salier, J.P.3
  • 126
    • 0026317133 scopus 로고
    • Factor B (BF) allotypes and multiple sclerosis in north-east England
    • Papiha SS, Duggan-Keen M, Roberts DF. Factor B (BF) allotypes and multiple sclerosis in north-east England. Hum Heredity 1991 ; 41 : 397-402.
    • (1991) Hum Heredity , vol.41 , pp. 397-402
    • Papiha, S.S.1    Duggan-Keen, M.2    Roberts, D.F.3
  • 127
    • 0028020987 scopus 로고
    • The dissemination of multiple sclerosis: A Viking saga? A historical essay
    • Poser CM. The dissemination of multiple sclerosis: A Viking saga? A historical essay. Ann Neurol 1994 ; 36 Suppl 2 : S231-43.
    • (1994) Ann Neurol , vol.36 , Issue.SUPPL. 2
    • Poser, C.M.1
  • 129
    • 0001741970 scopus 로고
    • The familial incidence of multiple sclerosis and its significance
    • Pratt RTC, Compston ND, McAlpine D. The familial incidence of multiple sclerosis and its significance. Brain 1951 ; 74 : 191-232.
    • (1951) Brain , vol.74 , pp. 191-232
    • Pratt, R.T.C.1    Compston, N.D.2    McAlpine, D.3
  • 130
    • 0028949749 scopus 로고
    • The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation
    • Riordan-Eva P, Sanders MD, Govan GG, Sweeney MG, Da Costa J, Harding AE. The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation. Brain 1995 ; 118 : 319-37.
    • (1995) Brain , vol.118 , pp. 319-337
    • Riordan-Eva, P.1    Sanders, M.D.2    Govan, G.G.3    Sweeney, M.G.4    Da Costa, J.5    Harding, A.E.6
  • 131
    • 0026077774 scopus 로고
    • Consanguinity and multiple sclerosis in Orkney
    • Roberts DF. Consanguinity and multiple sclerosis in Orkney. Gen Epidemiol 1991 ; 8 : 147-51.
    • (1991) Gen Epidemiol , vol.8 , pp. 147-151
    • Roberts, D.F.1
  • 133
    • 0029810384 scopus 로고    scopus 로고
    • Clinical concordance in sibling pairs with multiple sclerosis
    • Robertson NP, Clayton D, Fraser MA, et al. Clinical concordance in sibling pairs with multiple sclerosis. Neurology 1996 ; 47 : 347-52.
    • (1996) Neurology , vol.47 , pp. 347-352
    • Robertson, N.P.1    Clayton, D.2    Fraser, MA.3
  • 134
    • 0009508827 scopus 로고
    • Incidence of MS in Macomer, Sardinia, 1912-1981
    • Rosati G, Aiello I, Granieri E, et al. Incidence of MS in Macomer, Sardinia, 1912-1981. Neurology 1986 ; 36 : 1419.
    • (1986) Neurology , vol.36 , pp. 1419
    • Rosati, G.1    Aiello, I.2    Granieri, E.3
  • 135
    • 0026010242 scopus 로고
    • HLA-DPB1 gene polymorphism and multiple sclerosis: A large case-control study in the southwest of France
    • Roth MP, Coppin H, Descoins P, et al. HLA-DPB1 gene polymorphism and multiple sclerosis: A large case-control study in the southwest of France. J Neuroimmunol 1991 ; 34 : 215-22.
    • (1991) J Neuroimmunol , vol.34 , pp. 215-222
    • Roth, M.P.1    Coppin, H.2    Descoins, P.3
  • 136
    • 0028835240 scopus 로고
    • Myelin Oligodendrocyte Glycoprotein (MOG) gene polymorphism and multiple sclerosis: No evidence of disease association with MOG
    • Roth MP, Dolbois L, Borot N, et al. Myelin Oligodendrocyte Glycoprotein (MOG) gene polymorphism and multiple sclerosis: No evidence of disease association with MOG. J Neuroimmunol 1995 ; 61 : 117-22.
    • (1995) J Neuroimmunol , vol.61 , pp. 117-122
    • Roth, M.P.1    Dolbois, L.2    Borot, N.3
  • 137
    • 0028288398 scopus 로고
    • Tumor necrosis factor polymorphism in multiple sclerosis: No additional association independent of HLA
    • Roth MP, Nogueira L, Coppin H, et al. Tumor necrosis factor polymorphism in multiple sclerosis: No additional association independent of HLA. J Neuroimmunol 1994 ; 51 : 93-9.
    • (1994) J Neuroimmunol , vol.51 , pp. 93-99
    • Roth, M.P.1    Nogueira, L.2    Coppin, H.3
  • 138
    • 0027164123 scopus 로고
    • Familial recurrence risk and inheritance of multiple sclerosis
    • Sadovnick AD. Familial recurrence risk and inheritance of multiple sclerosis. Curr Opin Neurol Neurosurg 1993 ; 6 : 189-94.
    • (1993) Curr Opin Neurol Neurosurg , vol.6 , pp. 189-194
    • Sadovnick, A.D.1
  • 139
    • 0027537583 scopus 로고
    • A population-based twin study of multiple sclerosis in twins: Update
    • Sadovnick AD, Armstrong H, Rice GPA, et al. A population-based twin study of multiple sclerosis in twins: Update. Ann Neurol 1993 ; 33 : 281-5.
    • (1993) Ann Neurol , vol.33 , pp. 281-285
    • Sadovnick, A.D.1    Armstrong, H.2    Rice, G.P.A.3
  • 140
    • 0023898286 scopus 로고
    • The familial nature of multiple sclerosis: Age-corrected empiric recurrence risks for children and siblings of patients
    • Sadovnick AD, Baird PA. The familial nature of multiple sclerosis: Age-corrected empiric recurrence risks for children and siblings of patients. Neurology 1988 ; 38 : 990-1.
    • (1988) Neurology , vol.38 , pp. 990-991
    • Sadovnick, A.D.1    Baird, P.A.2
  • 141
    • 0023897491 scopus 로고
    • Multiple sclerosis: Updated risks for relatives
    • Sadovnick AD, Baird PA, Ward RH. Multiple sclerosis: Updated risks for relatives. Am J Med Gen 1988 ; 29 : 533-41.
    • (1988) Am J Med Gen , vol.29 , pp. 533-541
    • Sadovnick, A.D.1    Baird, P.A.2    Ward, R.H.3
  • 142
    • 0026013435 scopus 로고
    • Parent-child concordance in multiple sclerosis
    • Sadovnick AD, Bulman D, Ebers GC. Parent-child concordance in multiple sclerosis. Ann Neurol 1991 ; 29 : 252-5.
    • (1991) Ann Neurol , vol.29 , pp. 252-255
    • Sadovnick, A.D.1    Bulman, D.2    Ebers, G.C.3
  • 143
    • 0030007661 scopus 로고    scopus 로고
    • Evidence for genetic basis of multiple sclerosis
    • Sadovnick AD, Ebers GC, Dyment DA, et al. Evidence for genetic basis of multiple sclerosis. Lancet 1996 ; 347 : 1728-30.
    • (1996) Lancet , vol.347 , pp. 1728-1730
    • Sadovnick, A.D.1    Ebers, G.C.2    Dyment, D.A.3
  • 144
    • 0019499988 scopus 로고
    • Familial nature of multiple sclerosis: Empiric risks for first, second and third degree relatives of patients
    • Sadovnick AD, MacLeod PMJ. Familial nature of multiple sclerosis: Empiric risks for first, second and third degree relatives of patients. Neurology 1981 ; 31 : 1039-41.
    • (1981) Neurology , vol.31 , pp. 1039-1041
    • Sadovnick, A.D.1    MacLeod, P.M.J.2
  • 146
    • 0022468146 scopus 로고
    • Combined influences of Gm and HLA phenotypes upon multiple sclerosis susceptibility and severity
    • Salier JP, Sesboue R, Martin-Moncliere C, et al. Combined influences of Gm and HLA phenotypes upon multiple sclerosis susceptibility and severity. J Clin Invest 1986 ; 78 : 533-8.
    • (1986) J Clin Invest , vol.78 , pp. 533-538
    • Salier, J.P.1    Sesboue, R.2    Martin-Moncliere, C.3
  • 147
    • 0029395614 scopus 로고
    • An evaluation of tumor necrosis factor microsatellite alleles in genetic susceptibility to multiple sclerosis
    • Sandberg-Wollheim M, Ciusani E, Salmaggi A, et al. An evaluation of tumor necrosis factor microsatellite alleles in genetic susceptibility to multiple sclerosis. Multiple Sclerosis 1995 ; 1 : 181-5.
    • (1995) Multiple Sclerosis , vol.1 , pp. 181-185
    • Sandberg-Wollheim, M.1    Ciusani, E.2    Salmaggi, A.3
  • 148
    • 15844368830 scopus 로고    scopus 로고
    • A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
    • Sawcer S, Jones HB, Feakes R, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nature Genet 1996 ; 13 : 464-8.
    • (1996) Nature Genet , vol.13 , pp. 464-468
    • Sawcer, S.1    Jones, H.B.2    Feakes, R.3
  • 149
    • 0024406282 scopus 로고
    • A susceptibility locus for multiple sclerosis is linked to the T-cell receptor β-chain complex
    • Seboun E, Robinson MA, Doolittle TH, et al. A susceptibility locus for multiple sclerosis is linked to the T-cell receptor β-chain complex. Cell 1989 ; 57 : 1095-100.
    • (1989) Cell , vol.57 , pp. 1095-1100
    • Seboun, E.1    Robinson, MA.2    Doolittle, T.H.3
  • 150
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Canella B, Brosnan CF. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991 ; 87 : 949-54.
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Canella, B.3    Brosnan, C.F.4
  • 151
    • 0009508829 scopus 로고
    • HLA genetic factors involved in familial MS: RFLP study defines a particular DQw1 subtype associated with the disease
    • Confavreux C, Aimard G, Deic M, eds. New York: Elsevier
    • Semana G, Quillivic F, Madigand M, et al. HLA genetic factors involved in familial MS: RFLP study defines a particular DQw1 subtype associated with the disease. In: Confavreux C, Aimard G, Deic M, eds. Trends in European Multiple Sclerosis. New York: Elsevier; 1988. p. 21-6.
    • (1988) Trends in European Multiple Sclerosis , pp. 21-26
    • Semana, G.1    Quillivic, F.2    Madigand, M.3
  • 152
    • 0023099852 scopus 로고
    • Occurrence of multiple sclerosis in the north and south of New Zealand
    • Skegg D, Corwin P, Craven R, et al. Occurrence of multiple sclerosis in the north and south of New Zealand. J Neurol Neurosurg Psychiatry 1987 ; 50 : 134-9.
    • (1987) J Neurol Neurosurg Psychiatry , vol.50 , pp. 134-139
    • Skegg, D.1    Corwin, P.2    Craven, R.3
  • 153
    • 0030918147 scopus 로고    scopus 로고
    • The HLA-DQ (alpha 1 *0102, beta 1 *0602) heterodimer may confer susceptibility to multiple sclerosis in the absence of the HLA-DR (alpha 1 *01, beta 1 *1501) heterodimer
    • Spurkland A, Celius EG, Knutsen I, el al. The HLA-DQ (alpha 1 *0102, beta 1 *0602) heterodimer may confer susceptibility to multiple sclerosis in the absence of the HLA-DR (alpha 1 *01, beta 1 *1501) heterodimer. Tissue Antigens 1997 ; 50 : 15-22.
    • (1997) Tissue Antigens , vol.50 , pp. 15-22
    • Spurkland, A.1    Celius, E.G.2    Knutsen, I.3
  • 154
    • 0028285712 scopus 로고
    • No association of multiple sclerosis to alleles at the TAP2 locus
    • Spurkland A, Knutsen I, Undlien DE, Vandal F. No association of multiple sclerosis to alleles at the TAP2 locus. Hum Immunol 1994 ; 39 : 299-301.
    • (1994) Hum Immunol , vol.39 , pp. 299-301
    • Spurkland, A.1    Knutsen, I.2    Undlien, D.E.3    Vandal, F.4
  • 155
    • 0026003986 scopus 로고
    • HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis
    • Spurkland A, Ronningen KS, Vandvik B, et al. HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis. Hum Immunol 1991 ; 30 : 69-75.
    • (1991) Hum Immunol , vol.30 , pp. 69-75
    • Spurkland, A.1    Ronningen, K.S.2    Vandvik, B.3
  • 156
    • 0018645864 scopus 로고
    • Strong linkage disequilibrium between HLA-Dw2 and BfS in multiple sclerosis ad in normal population
    • Stewart GJ, Basten A, Kirk RL. Strong linkage disequilibrium between HLA-Dw2 and BfS in multiple sclerosis ad in normal population. Tissue Antigens 1979 ; 14 : 86-97.
    • (1979) Tissue Antigens , vol.14 , pp. 86-97
    • Stewart, G.J.1    Basten, A.2    Kirk, R.L.3
  • 157
    • 0030939801 scopus 로고    scopus 로고
    • HLA-DR, DQA1 and DQB1 associations in Australian multiple sclerosis patients
    • Stewart GJ, Teutsch SM, Castle M, et al. HLA-DR, DQA1 and DQB1 associations in Australian multiple sclerosis patients. Eur J Immunogen 1997 ; 24 : 81-92.
    • (1997) Eur J Immunogen , vol.24 , pp. 81-92
    • Stewart, G.J.1    Teutsch, S.M.2    Castle, M.3
  • 158
    • 85058253507 scopus 로고
    • Multiple sclerosis susceptibility and the tumor necrosis factors
    • Sumner SM, Ebers GC. Multiple sclerosis susceptibility and the tumor necrosis factors. Am J Hum Genet 1993 ; 53 : S1086.
    • (1993) Am J Hum Genet , vol.53
    • Sumner, S.M.1    Ebers, G.C.2
  • 159
    • 0000134011 scopus 로고
    • Observation on the prevalence of multiple sclerosis in northern Scotland
    • Sutherland JM. Observation on the prevalence of multiple sclerosis in northern Scotland. Brain 1956 ; 79 : 635-54.
    • (1956) Brain , vol.79 , pp. 635-654
    • Sutherland, J.M.1
  • 160
    • 0022507079 scopus 로고
    • The distribution of multiple sclerosis in the United Kingdom
    • Swingler RJ, Compston DAS. The distribution of multiple sclerosis in the United Kingdom. J Neurol Neurosurg Psychiatry 1986 ; 49 : 1115-24.
    • (1986) J Neurol Neurosurg Psychiatry , vol.49 , pp. 1115-1124
    • Swingler, R.J.1    Compston, D.A.S.2
  • 163
    • 0027793427 scopus 로고
    • Reappraisal of HLA in multiple sclerosis: Close linkage in multiplex families
    • Tienari PJ, Wikstrom J, Koskimies S, et al. Reappraisal of HLA in multiple sclerosis: Close linkage in multiplex families. Eur J Hum Genet 1993 ; 1 : 257-68.
    • (1993) Eur J Hum Genet , vol.1 , pp. 257-268
    • Tienari, P.J.1    Wikstrom, J.2    Koskimies, S.3
  • 164
    • 0026670087 scopus 로고
    • Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene
    • Tienari PJ, Wikstrom J, Sajantila A, et al. Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene. Lancet 1992 ; 340 : 987-91.
    • (1992) Lancet , vol.340 , pp. 987-991
    • Tienari, P.J.1    Wikstrom, J.2    Sajantila, A.3
  • 165
    • 0002621639 scopus 로고
    • Multiple sclerosis
    • Tiwari JL, Terasaki PI, eds. New York: Springier-Verlag
    • Tiwari JL, Terasaki PI. Multiple sclerosis. In: Tiwari JL, Terasaki PI, eds. HLA and Disease Associations. New York: Springier-Verlag; 1985. p. 152-67.
    • (1985) HLA and Disease Associations , pp. 152-167
    • Tiwari, J.L.1    Terasaki, P.I.2
  • 166
    • 0009573338 scopus 로고    scopus 로고
    • A complete genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex
    • The Multiple Sclerosis Genetics Group. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex. Nature Genet 1996 ; 13 : 469-71.
    • (1996) Nature Genet , vol.13 , pp. 469-471
  • 168
    • 0028095263 scopus 로고
    • mtDNA and the origin of Caucasians: Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region
    • Torroni A, Lott MT, Cabell MF, Chen YS, Lavergne L, Wallace DC. mtDNA and the origin of Caucasians: Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region. Am J Hum Genet 1994 ; 55 : 760-76.
    • (1994) Am J Hum Genet , vol.55 , pp. 760-776
    • Torroni, A.1    Lott, M.T.2    Cabell, M.F.3    Chen, Y.S.4    Lavergne, L.5    Wallace, D.C.6
  • 169
  • 170
    • 0031794471 scopus 로고    scopus 로고
    • Interferon-γ gene polymorphism-associated risk for multiple sclerosis in Sardinia
    • Vandenbroeck K, Opdenakker G, Goris A, et al. Interferon-γ gene polymorphism-associated risk for multiple sclerosis in Sardinia. Ann Neurol 1998 ; 44 : 841.
    • (1998) Ann Neurol , vol.44 , pp. 841
    • Vandenbroeck, K.1    Opdenakker, G.2    Goris, A.3
  • 171
    • 0028170324 scopus 로고
    • Polymorphism of the tumor necrosis factor beta gene in multiple sclerosis and rheumatoid arthritis
    • Vandevyver C, Raus P, Stinissen P, et al. Polymorphism of the tumor necrosis factor beta gene in multiple sclerosis and rheumatoid arthritis. Eur J Immunogenet 1994 ; 21 : 377-82.
    • (1994) Eur J Immunogenet , vol.21 , pp. 377-382
    • Vandevyver, C.1    Raus, P.2    Stinissen, P.3
  • 172
    • 0027985360 scopus 로고
    • TAP1 and TAP2 transporter gene polymorphisms in multiple sclerosis: No evidence for disease association with TAP
    • Vandevyver C, Stinissen P, Cassiman JJ, Raus J. TAP1 and TAP2 transporter gene polymorphisms in multiple sclerosis: No evidence for disease association with TAP. J Neuroimmunol 1994 ; 54 : 35-40.
    • (1994) J Neuroimmunol , vol.54 , pp. 35-40
    • Vandevyver, C.1    Stinissen, P.2    Cassiman, J.J.3    Raus, J.4
  • 173
    • 0024394725 scopus 로고
    • Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences
    • Vartdal F, Dollid L, Vandvik B, et al. Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences. Hum Immunol 1989 ; 25 : 103-10.
    • (1989) Hum Immunol , vol.25 , pp. 103-110
    • Vartdal, F.1    Dollid, L.2    Vandvik, B.3
  • 174
    • 0027409378 scopus 로고
    • A functional basis for the association of HLA class II genes and susceptibility to multiple sclerosis: Cellular immune response to myelin basic protein in a multiplex family
    • Voskuhl RR, Martin R, McFarland HF. A functional basis for the association of HLA class II genes and susceptibility to multiple sclerosis: Cellular immune response to myelin basic protein in a multiplex family. J Neuroimmunol 1993 ; 42 : 187-92.
    • (1993) J Neuroimmunol , vol.42 , pp. 187-192
    • Voskuhl, R.R.1    Martin, R.2    McFarland, H.F.3
  • 175
    • 0029899731 scopus 로고    scopus 로고
    • DR2/DQw1 inheritance and haplotype sharing in affected siblings from multiple sclerosis families
    • Voskuhl R, Goldstein AM, Simonis T, et al. DR2/DQw1 inheritance and haplotype sharing in affected siblings from multiple sclerosis families. Ann Neurol 1996 ; 39 : 804-7.
    • (1996) Ann Neurol , vol.39 , pp. 804-807
    • Voskuhl, R.1    Goldstein, A.M.2    Simonis, T.3
  • 176
    • 0028949050 scopus 로고
    • Human T-cell receptor V β gene polymorphism and multiple sclerosis
    • Wei S, Charmley P, Birchfield RI, et al. Human T-cell receptor V β gene polymorphism and multiple sclerosis. Am J Hum Genet 1995 ; 56 : 963-9.
    • (1995) Am J Hum Genet , vol.56 , pp. 963-969
    • Wei, S.1    Charmley, P.2    Birchfield, R.I.3
  • 177
    • 0028928973 scopus 로고
    • The natural history of multiple sclerosis
    • Weinshenker BG. The natural history of multiple sclerosis. Neurol Clin 1995 ; 13 : 119-46.
    • (1995) Neurol Clin , vol.13 , pp. 119-146
    • Weinshenker, B.G.1
  • 178
    • 0031783392 scopus 로고    scopus 로고
    • Major histocompatibility complex class II alleles and the course and outcome of MS. A population-based study
    • Weinshenker BG, Santrach P, Bissonet AS, et al. Major histocompatibility complex class II alleles and the course and outcome of MS. A population-based study. Neurology 1998 ; 51 : 742-7.
    • (1998) Neurology , vol.51 , pp. 742-747
    • Weinshenker, B.G.1    Santrach, P.2    Bissonet, A.S.3
  • 179
    • 0030766640 scopus 로고    scopus 로고
    • Genetic variation in the tumor necrosis factor alpha gene and the outcome of multiple sclerosis
    • Weinshenker BG, Wingerchuk DM, Liu Q, et al. Genetic variation in the tumor necrosis factor alpha gene and the outcome of multiple sclerosis. Neurology 1997 ; 49 : 378-85.
    • (1997) Neurology , vol.49 , pp. 378-385
    • Weinshenker, B.G.1    Wingerchuk, D.M.2    Liu, Q.3
  • 181
    • 0030845612 scopus 로고    scopus 로고
    • A population-based case-control study of the tumor necrosis factor alpha 308 polymorphism in multiple sclerosis
    • Wingerchuk D, Liu Q, Sobell J, et al. A population-based case-control study of the tumor necrosis factor alpha 308 polymorphism in multiple sclerosis. Neurology 1997 ; 49 : 626-8.
    • (1997) Neurology , vol.49 , pp. 626-628
    • Wingerchuk, D.1    Liu, Q.2    Sobell, J.3
  • 182
    • 0028117904 scopus 로고
    • No linkage or association between multiple sclerosis and the myelin basic protein gene in affected sibling pairs
    • Wood NW, Holmans P, Clayton D, et al. No linkage or association between multiple sclerosis and the myelin basic protein gene in affected sibling pairs. J Neurol Neurosurg Psychiatry 1994 ; 57 : 1191-4.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 1191-1194
    • Wood, N.W.1    Holmans, P.2    Clayton, D.3
  • 183
    • 0028808578 scopus 로고
    • A susceptibility gene for multiple sclerosis linked to immunoglobulin heavy chain variable region
    • Wood NW, Sawcer S, Kellar Wood HF, et al. A susceptibility gene for multiple sclerosis linked to immunoglobulin heavy chain variable region. J Neurol 1995 ; 242 : 677-82.
    • (1995) J Neurol , vol.242 , pp. 677-682
    • Wood, N.W.1    Sawcer, S.2    Kellar Wood, H.F.3


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