Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse Chromosome 3

Mammalian Genome

Volumn 9, Issue 4, 1998, Pages 283-286

  Podolin, P L ^a   Denny, P ^b   Armitage, N ^c   Lord, C J ^c   Hill, N J ^c   Levy, E R ^d   Peterson, L B ^a   Todd, J A ^c   Wicker, L S ^a   Lyons, P A ^c  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MRC Mouse Genome Centre   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMAL LOCALIZATION; DISEASE DIAGNOSIS; MAMMALIAN GENETICS; MOUSE;

ANIMALS; CHROMOSOME MAPPING; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; MICE; MICE, INBRED NOD;

MAMMALIA;

EID: 7144263739     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900749     Document Type: Article

References (12)

1. Denny P, Lord CJ, Hill NJ, Goy JV, Levy ER, Podolin PL, Peterson LB, Wicker LS, Todd JA, Lyons PA (1997) Mapping of the IDDM locus, Idd3 to a 0.35-cM interval containing the Interleukin-2 gene. Diabetes 46, 695-700
2. Ghosh S, Palmer S, Rodrigues N, Cordell H, Hearne C, Cornall R, Prins J-B, McShane P, Lathrop G, Peterson L, Wicker L, Todd J (1993) Polygenic control of autoimmune diabetes in nonobese diabetic mice. Nat Genet 4, 404-409
3. Ikegami H, Makino S, Yamato E, Kawaguchi Y, Ueda H, Sakamoto T, Takekawa K, Ogihara T (1995) Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping. J Clin Invest 96, 1936-1942
4. Lord CJ, Bohlander SK, Hopes EA, Montague CT, Hill NJ, Prins J-B, Renjilian RJ, Peterson LB, Wicker LS, Todd JA, Denny P (1995) Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains. Mamm Genome 6, 563-570
5. Makino S, Kunimoto K, Muraoka Y, Mizushima Y, Katagiri K, Tochino Y (1980) Breeding of a non-obese diabetic strain of mice. Exp Anim 29, 1-13
6. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16, 7738
7. Podolin PL, Denny P, Lord CJ, Hill NJ, Todd JA, Peterson LB, Wicker LS, Lyons PA (1997) Congenic mapping of the insulin dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect, and eliminates the candidate Fcgrl. J Immunol 159, 1835-1843
8. Sundvall M, Jirholt J, Yang H-T, Jansson L, Engström Å, Pettersson U, Holmdahl R (1995) Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis. Nat Genet 10, 313-317
9. Tochino Y (1987) The NOD mouse as a model of type 1 diabetes. CRC Crit Rev Immunol 8, 49-81
10. Todd JA, Aitman TJ, Cornall RJ, Ghosh, S, Hall JRS, Hearne CM, Knight AM, Love JM, McAleer MA, Prins J-B, Rodrigues N, Lathrop M, Pressey A, DeLarato NH, Peterson LB, Wicker LS (1991) Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature 351, 542-547
11. Wicker LS, Todd JA, Prins J-B, Podolin PL, Renjilian RJ, Peterson LB (1994) Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3. Idd3 and Idd10, protect nonohese diabetic mice from diabetes. J Exp Med 180, 1705-1713
12. Wicker LS, Todd JA, Peterson LB (1995) Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 13, 179-200