Enhanced susceptibility to lupus contributed from the nonautoimmune C57BL/10, but not C57BL/6, genome

Journal of Immunology

Volumn 164, Issue 10, 2000, Pages 5515-5521

  Rozzo, Stephen J ^a,b   Vyse, Timothy J ^b,d   Menze, Katherine ^a   Izui, Shozo ^c   Kotzin, Brian L ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^d IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CHROMOSOME 13; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; IMMUNOPATHOGENESIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0034658345     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.10.5515     Document Type: Article

References (35)

1. Howie, J. B., and B. J. Helyer. 1968. The immunology and pathology of NZB mice. Adv. Immunol. 9:215.
2. Theofilopoulos, A. N. 1992. Murine models of systemic lupus erythematosus. In Systemic Lupus Erythematosus. R. G. Lahita, ed. Churchill Livingstone, New York, p. 121.
3. Kotzin, B. L. 1996. Systemic lupus erythematosus. Cell 85:303.
4. Madaio, M. P., J. Carlson, J. Cataldo, A. Ucci, P. Migliorini, and O. Pankewycz. 1987. Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. J. Immunol. 138:2883.
5. Raz, E., M. Brezis, E. Rosenmann, and D. Eilat. 1989. Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused kidney. J. Immunol. 142:3076.
6. Tsao, B. P., K. Ohnishi, H Cheroutre, B. Mitchell, M. Teitell, P. Mixter, M. Kronenberg, and B. H. Hahn. 1992. Failed self-tolerance and autoimmunity in IgG anti-DNA transgene mice. J. Immunol. 140:350.
7. Izui, S., P. J. McConahey, A. N. Theofilopoulos, and F. J. Dixon. 1979. Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. J. Exp. Med. 149:1099.
8. Izui, S., J. H. Elder, P. J. McConahey, and F. J. Dixon. 1981. Identification of retroviral gp70 and anti-gp70 antibodies involved in circulating immune complexes in NZB × NZW mice. J. Exp. Med. 153:1151.
9. 2 mice with murine lupus nephritis. J. Exp. Med. 154:517.
10. 1 hybrid and the correlation to renal disease. J. Immunol. 130:740.
11. Vyse, T. J., C. G. Drake, S. J. Rozzo, E. Roper, S. Izui, and B. L. Kotzin. 1996. Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice. J. Clin. Invest. 98:1762.
12. Vyse, T. J., and B. L. Kotzin. 1998. Genetic susceptibility to systemic lupus erythematosus. Annu. Rev. Immunol. 16:261.
13. b genes to lupus susceptibility in New Zealand mice. J. Immunol. 160:2757.
14. Rozzo, S. J., T. J. Vyse, C. S. David, E. Palmer, S. Izui, and B. L. Kotzin. 1999. Analysis of MHC class II genes in the susceptibility to lupus in New Zealand mice. J. Immunol. 162:2623.
15. Rozzo, S. J., T. J. Vyse, C. G. Drake, and B. L. Kotzin. 1996. Effect of genetic background on the contribution of New Zealand Black loci to autoimmune lupus nephritis. Proc. Natl. Acad. Sci. USA 93:15164.
16. Vyse, T. J., S. J. Rozzo, C. G. Drake, S. Izui, and B. L. Kotzin. 1997. Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand Black mice. J. Immunol. 158:5566.
17. 1 mice. J. Exp. Med. 165:1237.
18. Drake, C. G., S. J. Rozzo, H. F. Hirschfeld, N. P. Smarnworawong, E. Palmer, and B. L. Kotzin. 1995. Analysis of the New Zealand Black contribution to lupus-like renal disease: multiple genes that operate in a threshold manner. J. Immunol. 154:2441.
19. Burlingame, R. W., and R. L. Rubin. 1990. Subnucleosome structures as substrates in enzyme-linked immunosorbent assays. J. Immunol. Methods 133:187.
20. Izui, S., and G. Lange. 1983. Enzyme-linked immunosorbent assay for detection of retroviral gp70 and gp70-anti-gp70 immune complexes in sera from SLE mice. Clin. Exp. Immunol. 71:45.
21. Rosner, B. 1990. Hypothesis testing: categorical data. In Fundamentals of Biostatistics. PWS-KENT Publishing Co., Boston, p. 318.
22. Lander, E. S., P. Green, J. Abrahamson, A. Barlow, M. J. Daly, S. E. Lincoln, and L. Newburg. 1987. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1:174.
23. Lincoln, S. E., M. Daly, and E. S. Lander. 1992. Mapping Genes Controlling Quantitative Traits with MAPMAKER/QTL 1.1. Whitehead Institute, Cambridge.
24. Lander, E. S., and D. Botstein. 1989. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185.
25. Lander, E. S., and L. Kruglyak. 1995. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. 11:241.
26. Festing, M. F. W. 1992. Origins and characteristics of inbred strains of mice, 14th listing. Mouse Genome 90:231.
27. Slingsby, J. H., M. B. Hogarth, E. Simpson, M. J. Walport, and B. J. Morley. 1995. New microsatellite polymorphisms identified between C57BL/6, C57BL/10 and C57BL/KsJ inbred mouse strains. Immunogenetics 43:72.
28. McClive, P. J., D. Huang, and G. Morahan. 1994. C57BL/6 and C57BL/10 inbred mouse strains differ at multiple loci on chromosome 4. Immunogenetics 39:286.
29. Wakeland, E. K., A. E. Wandstrat, K. Liu, and L. Morel. 1999. Genetic dissection of systemic lupus erythematosus. Curr. Opin. Immunol. 11:701.
30. Vyse, T. J., R. K. Halterman, S. J. Rozzo, S. Izui, and B. L. Kotzin. 1999. Control of separate pathogenic autoantibody responses marks MHC gene contributions to murine lupus. Proc. Natl. Acad. Sci. USA 96:8098.
31. 1 mice. Eur. J. Immunol. 28:4257.
32. Frankel, W. N., J. P. Stoye, B. A. Taylor, and J. M. Coffin. 1990. A linkage map of endogenous murine leukemia proviruses. Genetics 124:221.
33. Vyse, T. J., L. Morel, F. J. Tanner, E. K. Wakeland, and B. L. Kotzin. 1996. Backcross analysis of genes linked to autoantibody production in New Zealand White mice. J. Immunol. 157:2719.
34. Morel, L., X.-H. Tian, B. P. Croker, and E. K. Wakeland. 1999. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity 11:131.
35. Wu, J.-M., J. A. Longmate, G. Adamus, P. A. Hargrave, and E. K. Wakeland. 1996. Interval mapping of quantitative trait loci controlling humoral immunity to exogenous antigens: evidence that non-MHC immune response genes may also influence susceptibility to autoimmunity. J. Immunol. 157:2498.