-
1
-
-
0033518007
-
Cancer progression
-
E. R. Fearon (1999). Cancer progression. Curr. Biol. 9: 873-875.
-
(1999)
Curr. Biol.
, vol.9
-
-
Fearon, E.R.1
-
2
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan and R. A. Weinberg (2000). The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0024315423
-
Morphogenesis of the polarized epithelial cell phenotype
-
E. Rodriguez-Boulan and W. J. Nelson (1989). Morphogenesis of the polarized epithelial cell phenotype. Science 245:718-725.
-
(1989)
Science
, vol.245
, pp. 718-725
-
-
Rodriguez-Boulan, E.1
Nelson, W.J.2
-
4
-
-
0034075654
-
Form and function: The laminin family of heterotrimers
-
H. Colognato and P. Yurchenco (2000). Form and function: The laminin family of heterotrimers. Developmental Dynamics 218:213-234.
-
(2000)
Developmental Dynamics
, vol.218
, pp. 213-234
-
-
Colognato, H.1
Yurchenco, P.2
-
5
-
-
0031713433
-
Extracellular matrix signaling: Integration of form and function in normal and malignant cells
-
N. Boudreau and M. J. Bissell (1998). Extracellular matrix signaling: Integration of form and function in normal and malignant cells. Curr. Opin. Cell. Biol. 10:640-646.
-
(1998)
Curr. Opin. Cell. Biol.
, vol.10
, pp. 640-646
-
-
Boudreau, N.1
Bissell, M.J.2
-
6
-
-
0033119507
-
Tissue structure, nuclear organization, and gene expression in normal and malignant breast
-
M. J. Bissell, V. M. Weaver, S. A. Lelievre, F. Wang, O. W. Petersen, and K. L. Schmeichel (1999). Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res. 59: 757-1763s.
-
(1999)
Cancer Res.
, vol.59
-
-
Bissell, M.J.1
Weaver, V.M.2
Lelievre, S.A.3
Wang, F.4
Petersen, O.W.5
Schmeichel, K.L.6
-
8
-
-
0030669932
-
Pancreatic carcinomas deposit laminin-5, preferably adhere to laminin-5, and migrate on the newly deposited basement membrane
-
T. Tani, A. Lumme, A. Linnala, E. Kivilaakso, T. Kiviluoto, R. E. Burgeson, L. Kangas, I. Leivo, and I. Virtanen (1997). Pancreatic carcinomas deposit laminin-5, preferably adhere to laminin-5, and migrate on the newly deposited basement membrane. Am. J. Pathol. 151: 289-1302.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1289-1302
-
-
Tani, T.1
Lumme, A.2
Linnala, A.3
Kivilaakso, E.4
Kiviluoto, T.5
Burgeson, R.E.6
Kangas, L.7
Leivo, I.8
Virtanen, I.9
-
9
-
-
0030447227
-
Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors
-
H. Mizushima, H., Y. Miyagi, Y. Kikkawa, N. Yamanaka, H. Yasumitsu, K. Misugi, and K. Miyazaki (1996). Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors. J. Biochem. (Tokyo). 120:1196-1202.
-
(1996)
J. Biochem. (Tokyo)
, vol.120
, pp. 1196-1202
-
-
Mizushima, H.1
Miyagi, H.Y.2
Kikkawa, Y.3
Yamanaka, N.4
Yasumitsu, H.5
Misugi, K.6
Miyazaki, K.7
-
10
-
-
0031456065
-
Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion
-
L. M. Shaw, I. Rabinovitz, H. H. Wang, A. Toker, and A. M. Mercurio (1997). Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion. Cell 91: 949-960.
-
(1997)
Cell
, vol.91
, pp. 949-960
-
-
Shaw, L.M.1
Rabinovitz, I.2
Wang, H.H.3
Toker, A.4
Mercurio, A.M.5
-
11
-
-
0033615961
-
p53 inhibits α6β4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKt/PKB
-
R. E. Bachelder, M. J. Ribick, A. Marchetti, R. Falcioni, S. Soddu, K. R. Davis, and A. M. Mercurio (1999). p53 inhibits α6β4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKt/PKB. J. Cell. Biol. 147:1063-1072.
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 1063-1072
-
-
Bachelder, R.E.1
Ribick, M.J.2
Marchetti, A.3
Falcioni, R.4
Soddu, S.5
Davis, K.R.6
Mercurio, A.M.7
-
12
-
-
0031794915
-
Migration of breast epithelial cells on Laminin-5: Differential role of integrins in normal and transformed cell types
-
G. E. Plopper, S. Z. Domanico, V. Cirulli, W. B. Kiosses, and V. Quaranta (1998). Migration of breast epithelial cells on Laminin-5: Differential role of integrins in normal and transformed cell types. Breast Cancer Res. Treat. 51:57-69.
-
(1998)
Breast Cancer Res. Treat.
, vol.51
, pp. 57-69
-
-
Plopper, G.E.1
Domanico, S.Z.2
Cirulli, V.3
Kiosses, W.B.4
Quaranta, V.5
-
13
-
-
0034614939
-
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
-
N. Koshikawa, G. Giannelli, V. Cirulli, K. Miyazaki, and V. Quaranta (2000). Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J. Cell. Biol. 148:615-624.
-
(2000)
J. Cell. Biol.
, vol.148
, pp. 615-624
-
-
Koshikawa, N.1
Giannelli, G.2
Cirulli, V.3
Miyazaki, K.4
Quaranta, V.5
-
14
-
-
0028802948
-
Receptors for the laminins. Achieving specificity through cooperation
-
A. Mercurio (1995). Receptors for the laminins. Achieving specificity through cooperation. Trends in Cell biology 5:419-423.
-
(1995)
Trends in Cell Biology
, vol.5
, pp. 419-423
-
-
Mercurio, A.1
-
15
-
-
0033201938
-
Integrin function in breast carcinoma progression
-
L. M. Shaw (1999). Integrin function in breast carcinoma progression. J. Mammary Gland. Biol. Neoplasia 4:367-376.
-
(1999)
J. Mammary Gland Biol. Neoplasia
, vol.4
, pp. 367-376
-
-
Shaw, L.M.1
-
16
-
-
0028813315
-
High expression level of α6 integrin in human breast carcinoma is correlated with reduced survival
-
K. Friedrichs, P. Ruiz, F. Franke, I. Gille, H. J. Terpe, and B. A. Imhof (1995). High expression level of α6 integrin in human breast carcinoma is correlated with reduced survival. Cancer Res. 55:901-906.
-
(1995)
Cancer Res.
, vol.55
, pp. 901-906
-
-
Friedrichs, K.1
Ruiz, P.2
Franke, F.3
Gille, I.4
Terpe, H.J.5
Imhof, B.A.6
-
17
-
-
0031914189
-
Prognostic value of α6β4 integrin expression in breast carcinomas is affected by laminin production from tumor cells
-
E. Tagliabue, C. Ghirelli, P. Squicciarini, P. Aiello, M. I. Colnaghi, and S. Menard (1998). Prognostic value of α6β4 integrin expression in breast carcinomas is affected by laminin production from tumor cells. Clin. Cancer Res. 4:407-410.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 407-410
-
-
Tagliabue, E.1
Ghirelli, C.2
Squicciarini, P.3
Aiello, P.4
Colnaghi, M.I.5
Menard, S.6
-
18
-
-
0030695152
-
The integrin α6β1 promotes the survival of metastatic human breast carcinoma cells in mice
-
U. M. Wewer, L. M. Shaw, R. Albrechtsen, and A. M. Mercurio (1997). The integrin α6β1 promotes the survival of metastatic human breast carcinoma cells in mice. Am. J. Pathol. 151:1191-1198.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1191-1198
-
-
Wewer, U.M.1
Shaw, L.M.2
Albrechtsen, R.3
Mercurio, A.M.4
-
19
-
-
0033147378
-
Increased levels of α6 integrins are associated with the metastatic phenotype of human breast cancer cells
-
R. Mukhopadhyay, R. L. Theriault, and J. E. Price (1999). Increased levels of α6 integrins are associated with the metastatic phenotype of human breast cancer cells. Clin. Exp. Metastasis 17:325-332.
-
(1999)
Clin. Exp. Metastasis
, vol.17
, pp. 325-332
-
-
Mukhopadhyay, R.1
Theriault, R.L.2
Price, J.E.3
-
20
-
-
0027333411
-
Tumor cell interactions with the extracellular matrix during invasion and metastasis
-
W. G. Stetler-Stevenson, S. Aznavoorian, and L. A. Liotta (1993). Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell. Biol. 9:541-573.
-
(1993)
Annu. Rev. Cell. Biol.
, vol.9
, pp. 541-573
-
-
Stetler-Stevenson, W.G.1
Aznavoorian, S.2
Liotta, L.A.3
-
21
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
E. D. Hay (1995). An overview of epithelio-mesenchymal transformation. Acta. Anat. (Basel) 154:8-20.
-
(1995)
Acta Anat. (Basel)
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
22
-
-
0032848957
-
Epithelial cell plasticity in development and tumor progression
-
J. P. Thiery and D. Chopin (1999). Epithelial cell plasticity in development and tumor progression. Cancer Metastasis Rev. 18: 1-42.
-
(1999)
Cancer Metastasis Rev.
, vol.18
, pp. 31-42
-
-
Thiery, J.P.1
Chopin, D.2
-
24
-
-
0033930954
-
E-cadherin-catenin cell-cell adhesion complex and human cancer
-
B. P. Wijnhoven, W. N. Dinjens, and M. Pignatelli (2000). E-cadherin-catenin cell-cell adhesion complex and human cancer. Br. J. Surg. 87:992-1005.
-
(2000)
Br. J. Surg.
, vol.87
, pp. 992-1005
-
-
Wijnhoven, B.P.1
Dinjens, W.N.2
Pignatelli, M.3
-
25
-
-
0032843036
-
Cadherins and catenins: Role in signal transduction and tumor progression
-
J. Behrens (1999). Cadherins and catenins: Role in signal transduction and tumor progression. Cancer Metastasis Rev. 18:15-30.
-
(1999)
Cancer Metastasis Rev.
, vol.18
, pp. 15-30
-
-
Behrens, J.1
-
27
-
-
0029240438
-
E-cadherin as a tumor (invasion) suppressor gene
-
W. Birchmeier (1995). E-cadherin as a tumor (invasion) suppressor gene. Bioessays 17:97-99.
-
(1995)
Bioessays
, vol.17
, pp. 97-99
-
-
Birchmeier, W.1
-
29
-
-
0028806271
-
Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells
-
L. M. Bergstraesser, G. Srinivasan, J. C. Jones, S. Stahl, and S. A. Weitzman (1995). Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells. Am. J. Pathol. 147: 823-1839.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 1823-1839
-
-
Bergstraesser, L.M.1
Srinivasan, G.2
Jones, J.C.3
Stahl, S.4
Weitzman, S.A.5
-
30
-
-
0030325051
-
The integrin α6β4 and the biology of carcinoma
-
I. Rabinovitz and A. M. Mercurio (1996). The integrin α6β4 and the biology of carcinoma. Biochem. Cell. Biol. 74:811-821.
-
(1996)
Biochem. Cell. Biol.
, vol.74
, pp. 811-821
-
-
Rabinovitz, I.1
Mercurio, A.M.2
-
31
-
-
0029661897
-
A function for the integrin α6β4 in the invasive properties of colorectal carcinoma cells
-
C. Chao, M. M. Lotz, A. C. Clarke, and A. M. Mercurio (1996). A function for the integrin α6β4 in the invasive properties of colorectal carcinoma cells. Cancer Res. 56:4811-4819.
-
(1996)
Cancer Res.
, vol.56
, pp. 4811-4819
-
-
Chao, C.1
Lotz, M.M.2
Clarke, A.C.3
Mercurio, A.M.4
-
32
-
-
0032523825
-
Downstream events in mammary gland morphogenesis mediated by reexpression of the α2β1 integrin: The role of the α6 and β4 integrin subunits
-
H. Sun, S. A. Santoro, and M. M. Zutter (1998). Downstream events in mammary gland morphogenesis mediated by reexpression of the α2β1 integrin: The role of the α6 and β4 integrin subunits. Cancer Res. 58:2224-2233.
-
(1998)
Cancer Res.
, vol.58
, pp. 2224-2233
-
-
Sun, H.1
Santoro, S.A.2
Zutter, M.M.3
-
33
-
-
0032517857
-
Release of cAMP gating by the α6β4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells
-
K. L. O'Connor, L. M. Shaw, and A. M. Mercurio (1998). Release of cAMP gating by the α6β4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells. J. Cell. Biol. 143:1749-1760.
-
(1998)
J. Cell. Biol.
, vol.143
, pp. 1749-1760
-
-
O'Connor, K.L.1
Shaw, L.M.2
Mercurio, A.M.3
-
34
-
-
0034455571
-
Androgen receptor expression in prostate carcinoma cells suppresses α6β4 integrin-mediated invasive phenotype
-
L. Bonaccorsi, V. Carloni, M. Muratori, A. Salvadori, A. Giannini, M. Carini, M. Serio, G. Forti, and E. Baldi (2000). Androgen receptor expression in prostate carcinoma cells suppresses α6β4 integrin-mediated invasive phenotype. Endocrinology 141: 172-3182.
-
(2000)
Endocrinology
, vol.141
, pp. 3172-3182
-
-
Bonaccorsi, L.1
Carloni, V.2
Muratori, M.3
Salvadori, A.4
Giannini, A.5
Carini, M.6
Serio, M.7
Forti, G.8
Baldi, E.9
-
35
-
-
0030045346
-
Cell migration: A physically integrated molecular process
-
D. A. Lauffenburger and A. F. Horwitz (1996). Cell migration: A physically integrated molecular process. Cell 84:359-369.
-
(1996)
Cell
, vol.84
, pp. 359-369
-
-
Lauffenburger, D.A.1
Horwitz, A.F.2
-
36
-
-
0031283128
-
The integrin α6β4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin- containing motility structures
-
I. Rabinovitz and A. M. Mercurio (1997). The integrin α6β4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin- containing motility structures. J. Cell. Biol. 139:1873-1884.
-
(1997)
J. Cell. Biol.
, vol.139
, pp. 1873-1884
-
-
Rabinovitz, I.1
Mercurio, A.M.2
-
37
-
-
0029666451
-
The intracellular functions of alpha6beta4 integrin are regulated by EGF
-
F. Mainiero, A. Pepe, M. Yeon, Y. Ren, and F. G. Giancotti (1996). The intracellular functions of alpha6beta4 integrin are regulated by EGF. J. Cell. Biol. 134:241-253.
-
(1996)
J. Cell. Biol.
, vol.134
, pp. 241-253
-
-
Mainiero, F.1
Pepe, A.2
Yeon, M.3
Ren, Y.4
Giancotti, F.G.5
-
38
-
-
0032845770
-
Protein kinase C-dependent mobilization of the α6β4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells
-
I. Rabinovitz, A. Toker, and A. M. Mercurio (1999). Protein kinase C-dependent mobilization of the α6β4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells. J. Cell. Biol. 146:1147-1160.
-
(1999)
J. Cell. Biol.
, vol.146
, pp. 1147-1160
-
-
Rabinovitz, I.1
Toker, A.2
Mercurio, A.M.3
-
39
-
-
0032734174
-
Cell adhesion molecules, signal transduction and cell growth
-
A. E. Aplin, A. K. Howe, and R. Juliano (1999). Cell adhesion molecules, signal transduction and cell growth. Curr. Opin. Cell. Biol. 11:737-744.
-
(1999)
Curr. Opin. Cell. Biol.
, vol.11
, pp. 737-744
-
-
Aplin, A.E.1
Howe, A.K.2
Juliano, R.3
-
40
-
-
0031459917
-
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
-
P. J. Keely, J. K. Westwick, I. P. Whitehead, C. J. Der, and L. V. Parise (1997). Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 390:632-636.
-
(1997)
Nature
, vol.390
, pp. 632-636
-
-
Keely, P.J.1
Westwick, J.K.2
Whitehead, I.P.3
Der, C.J.4
Parise, L.V.5
-
41
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
A. Toker and L. C. Cantley (1997). Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387:673-676.
-
(1997)
Nature
, vol.387
, pp. 673-676
-
-
Toker, A.1
Cantley, L.C.2
-
43
-
-
0031563765
-
α6β4 and α6β1 integrins associate with ErbB-2 in human carcinoma cell lines
-
R. Falcioni, A. Antonini, P. Nistico, S. Di Stefano, M. Crescenzi, P. G. Natali, and A. Sacchi (1997). α6β4 and α6β1 integrins associate with ErbB-2 in human carcinoma cell lines. Exp. Cell. Res. 236:76-85.
-
(1997)
Exp. Cell. Res.
, vol.236
, pp. 76-85
-
-
Falcioni, R.1
Antonini, A.2
Nistico, P.3
Di Stefano, S.4
Crescenzi, M.5
Natali, P.G.6
Sacchi, A.7
-
44
-
-
0034615933
-
Cooperative signaling between α6β4 integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion
-
D. Gambaletta, A. Marchetti, L. Benedetti, A. M. Mercurio, A. Sacchi, and R. Falcioni (2000). Cooperative signaling between α6β4 integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion. J. Biol. Chem. 275:10604-10610.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10604-10610
-
-
Gambaletta, D.1
Marchetti, A.2
Benedetti, L.3
Mercurio, A.M.4
Sacchi, A.5
Falcioni, R.6
-
46
-
-
0032911020
-
Bidirectional signaling between the cytoskeleton and integrins
-
S. M. Schoenwaelder and K. Burridge (1999). Bidirectional signaling between the cytoskeleton and integrins. Curr. Opin. Cell. Biol. 11:274-286.
-
(1999)
Curr. Opin. Cell. Biol.
, vol.11
, pp. 274-286
-
-
Schoenwaelder, S.M.1
Burridge, K.2
-
47
-
-
0034616174
-
Motility powered by supramolecular springs and ratchets
-
L. Mahadevan and P. Matsudaira (2000). Motility powered by supramolecular springs and ratchets. Science 288:95-100.
-
(2000)
Science
, vol.288
, pp. 95-100
-
-
Mahadevan, L.1
Matsudaira, P.2
-
48
-
-
0032583205
-
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
-
E. E. Sander, S. van Delft, J. P. ten Klooster, T. Reid, R. A. van der Kammen, F. Michiels, and J. G. Collard (1998). Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J. Cell. Biol. 143:1385-1398.
-
(1998)
J. Cell. Biol.
, vol.143
, pp. 1385-1398
-
-
Sander, E.E.1
van Delft, S.2
ten Klooster, J.P.3
Reid, T.4
van der Kammen, R.A.5
Michiels, F.6
Collard, J.G.7
-
49
-
-
0031948845
-
Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras
-
D. H. van Weering, J. de Rooij, B. Marte, J. Downward, J. L. Bos, and B. M. Burgering (1998). Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras. Mol. Cell. Biol. 18: 802-1811.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1802-1811
-
-
van Weering, D.H.1
de Rooij, J.2
Marte, B.3
Downward, J.4
Bos, J.L.5
Burgering, B.M.6
-
50
-
-
0033560747
-
Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
-
R. Meili, C. Ellsworth, S. Lee, T. B. Reddy, H. Ma, and R. A. Firtel (1999). Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18: 2092-2105.
-
(1999)
EMBO J.
, vol.18
, pp. 2092-2105
-
-
Meili, R.1
Ellsworth, C.2
Lee, S.3
Reddy, T.B.4
Ma, H.5
Firtel, R.A.6
-
51
-
-
0034707597
-
RhoA function in lamellae formation and migration is regulated by the α6β4 integrin and cAMP metabolism
-
K. L. O'Connor, B. K. Nguyen, and A. M. Mercurio (2000). RhoA function in lamellae formation and migration is regulated by the α6β4 integrin and cAMP metabolism. J. Cell. Biol. 148:253-258.
-
(2000)
J. Cell. Biol.
, vol.148
, pp. 253-258
-
-
O'Connor, K.L.1
Nguyen, B.K.2
Mercurio, A.M.3
-
52
-
-
0030813029
-
Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants
-
C. Laudanna, J. J. Campbell, and E. C. Butcher (1997). Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants. J. Biol. Chem. 272:24141-24144.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24141-24144
-
-
Laudanna, C.1
Campbell, J.J.2
Butcher, E.C.3
-
53
-
-
0032935495
-
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
-
K. Itoh, K. Yoshioka, H. Akedo, M. Uehata, T. Ishizaki, and S. Narumiya (1999). An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat. Med. 5:221-225.
-
(1999)
Nat. Med.
, vol.5
, pp. 221-225
-
-
Itoh, K.1
Yoshioka, K.2
Akedo, H.3
Uehata, M.4
Ishizaki, T.5
Narumiya, S.6
-
54
-
-
0032570796
-
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
-
K. Yoshioka, F. Matsumura, H. Akedo, and K. Itoh (1998). Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells. J. Biol. Chem. 273:5146-5154.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5146-5154
-
-
Yoshioka, K.1
Matsumura, F.2
Akedo, H.3
Itoh, K.4
-
55
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
S. M. Frisch and H. Francis (1994). Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell. Biol. 124:619-626.
-
(1994)
J. Cell. Biol.
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
56
-
-
0033594105
-
Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling
-
N. Farrelly, Y. J. Lee, J. Oliver, C. Dive, and C. H. Streuli (1999). Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. J. Cell. Biol. 144:1337-1348.
-
(1999)
J. Cell. Biol.
, vol.144
, pp. 1337-1348
-
-
Farrelly, N.1
Lee, Y.J.2
Oliver, J.3
Dive, C.4
Streuli, C.H.5
-
57
-
-
0030661566
-
Integrins, oncogenes, and anchorage independence
-
M. A. Schwartz (1997). Integrins, oncogenes, and anchorage independence. J. Cell. Biol. 139:575-578.
-
(1997)
J. Cell. Biol.
, vol.139
, pp. 575-578
-
-
Schwartz, M.A.1
-
59
-
-
0033405294
-
The hypoxic cell: A target for selective cancer therapy - Eighteenth Bruce F. Cain Memorial Award lecture
-
J. M. Brown (1999). The hypoxic cell: A target for selective cancer therapy - eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res. 59:5863-5870.
-
(1999)
Cancer Res.
, vol.59
, pp. 5863-5870
-
-
Brown, J.M.1
-
60
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
D. Hanahan and J. Folkman (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86:353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
61
-
-
0031969264
-
Angiogenesis and tumor metastasis
-
B. R. Zetter (1998). Angiogenesis and tumor metastasis. Annu. Rev. Med. 49:407-424.
-
(1998)
Annu. Rev. Med.
, vol.49
, pp. 407-424
-
-
Zetter, B.R.1
-
62
-
-
0032752063
-
Cellular survival: A play in three Akts
-
S. R. Datta, A. Brunet, and M. E. Greenberg (1999). Cellular survival: A play in three Akts. Genes Dev. 13:2905-2927.
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
63
-
-
0034175984
-
Understanding Ras: 'It ain't over 'til it's over'
-
J. M. Shields, K. Pruitt, A. McFall, A. Shaub, and C. J. Der (2000). Understanding Ras: 'it ain't over 'til it's over'. Trends Cell. Biol. 10:147-154.
-
(2000)
Trends Cell. Biol.
, vol.10
, pp. 147-154
-
-
Shields, J.M.1
Pruitt, K.2
McFall, A.3
Shaub, A.4
Der, C.J.5
-
64
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
L. C. Cantley and B. G. Neel (1999). New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc. Natl. Acad. Sci. U.S.A. 96: 240-4245.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
65
-
-
0034708482
-
Akt/Protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
-
A. Toker and A. C. Newton (2000). Akt/Protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J. Biol. Chem. 275:8271-8274.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8271-8274
-
-
Toker, A.1
Newton, A.C.2
-
66
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
A. Khwaja, P. Rodriguez-Viciana, S. Wennstrom, P. H. Warne, and J. Downward (1997). Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16: 2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
67
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
V. Stambolic, A. Suzuki, J. L. de la Pompa, G. M. Brothers, C. Mirtsos, T. Sasaki, J. Ruland, J. M. Penninger, D. P. Siderovski, and T. W. Mak (1998). Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95:29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
de la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
68
-
-
0031936353
-
Ras signalling and apoptosis
-
J. Downward (1998). Ras signalling and apoptosis. Curr. Opin. Genet. Dev. 8:49-54.
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 49-54
-
-
Downward, J.1
-
69
-
-
0029127042
-
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
-
A. Bellacosa, D. de Feo, A. K. Godwin, D. W. Bell, J. Q. Cheng, D. A. Altomare, M. Wan, L. Dubeau, G. Scambia, V. Masciullo, et al. (1995). Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int. J. Cancer 64:280-285.
-
(1995)
Int. J. Cancer
, vol.64
, pp. 280-285
-
-
Bellacosa, A.1
de Feo, D.2
Godwin, A.K.3
Bell, D.W.4
Cheng, J.Q.5
Altomare, D.A.6
Wan, M.7
Dubeau, L.8
Scambia, G.9
Masciullo, V.10
-
70
-
-
0034604067
-
Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer
-
Z. Q. Yuan, M. Sun, R. I. Feldman, G. Wang, X. Ma, C. Jiang, D. Coppola, S. V. Nicosia, and J. Q. Cheng (2000). Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer. Oncogene 19: 324-2330.
-
(2000)
Oncogene
, vol.19
, pp. 2324-2330
-
-
Yuan, Z.Q.1
Sun, M.2
Feldman, R.I.3
Wang, G.4
Ma, X.5
Jiang, C.6
Coppola, D.7
Nicosia, S.V.8
Cheng, J.Q.9
-
71
-
-
0033986790
-
The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis
-
K. Jiang, D. Coppola, N. C. Crespo, S. V. Nicosia, A. D. Hamilton, S. M. Sebti, and J. Q. Cheng (2000). The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis. Mol. Cell. Biol. 20:139-148.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 139-148
-
-
Jiang, K.1
Coppola, D.2
Crespo, N.C.3
Nicosia, S.V.4
Hamilton, A.D.5
Sebti, S.M.6
Cheng, J.Q.7
-
72
-
-
0033618371
-
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
-
K. Nakatani, D. A. Thompson, A. Barthel, H. Sakaue, W. Liu, R. J. Weigel, and R. A. Roth (1999). Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J. Biol. Chem. 274:21528-21532.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21528-21532
-
-
Nakatani, K.1
Thompson, D.A.2
Barthel, A.3
Sakaue, H.4
Liu, W.5
Weigel, R.J.6
Roth, R.A.7
-
73
-
-
0030063313
-
Function of the integrin α6β1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor
-
L. M. Shaw, C. Chao, U. M. Wewer, and A. M. Mercurio (1996). Function of the integrin α6β1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor. Cancer Res. 56: 59-963.
-
(1996)
Cancer Res.
, vol.56
, pp. 959-963
-
-
Shaw, L.M.1
Chao, C.2
Wewer, U.M.3
Mercurio, A.M.4
-
74
-
-
0034074486
-
Protein kinases as mediators of phosphoinositide 3-kinase signaling
-
A. Toker (2000). Protein kinases as mediators of phosphoinositide 3-kinase signaling. Mol. Pharmacol. 57:652-658.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 652-658
-
-
Toker, A.1
|