Protein kinase C-dependent mobilization of the α6β4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells

Journal of Cell Biology

Volumn 146, Issue 5, 1999, Pages 1147-1159

  Rabinovitz, Isaac ^a   Toker, Alex ^b   Mercurio, Arthur M ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Cell movement; Cytoskeleton; Hemidesmosomes; Integrins; PKC

Indexed keywords

ACTIN; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; INTEGRIN; LAMININ; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOTYROSINE; PROTEIN KINASE C;

ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CHEMOTAXIS; ENZYME ACTIVATION; HEMIDESMOSOME; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA;

ACTINS; ANTIGENS, SURFACE; CARBAZOLES; CARCINOMA, SQUAMOUS CELL; CELL MEMBRANE; CELL SIZE; CHEMOTAXIS; DESMOSOMES; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; INDOLES; INTEGRIN ALPHA6BETA4; INTEGRINS; KERATINS; LAMININ; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTYROSINE; PROTEIN KINASE C; PSEUDOPODIA; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0032845770     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.146.5.1147     Document Type: Article

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