-
1
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi, D. R., M. Andjelkovich, B. Caudwell, P. Cron, N. Morrice, P. Cohen, and B. A. Hemmings. 1996. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15:6541-6551.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovich, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
2
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B-alpha
-
Alessi, D. R., S. R. James, C. P. Downes, A. B. Holmes, P. R. Gaffney, C. B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B-alpha. Curr. Biol. 7:261-269.
-
(1997)
Curr. Biol.
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
3
-
-
85036604372
-
-
Unpublished data
-
2a. Burgering, B. M. T., et al. Unpublished data.
-
-
-
Burgering, B.M.T.1
-
4
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering, B. M. T., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.T.1
Coffer, P.J.2
-
5
-
-
0027450410
-
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity
-
Carpenter, C. L., K. R. Auger, B. C. Duckworth, W. M. Hou, B. Schaffhausen, and L. C. Cantley. 1993. A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol. Cell. Biol. 13: 1657-1665.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1657-1665
-
-
Carpenter, C.L.1
Auger, K.R.2
Duckworth, B.C.3
Hou, W.M.4
Schaffhausen, B.5
Cantley, L.C.6
-
6
-
-
0029890229
-
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1
-
Chou, M. M., and J. Blenis. 1996. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell 85:573.
-
(1996)
Cell
, vol.85
, pp. 573
-
-
Chou, M.M.1
Blenis, J.2
-
7
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross, D. A., D. R. Alessi, P. Cohen, M. Andjelkovich, and B. A. Hemmings. 1995. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
8
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Dalla, S. R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M. E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Dalla, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
10
-
-
0031055415
-
Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras
-
De Rooij, J., and J. L. Bos. 1997. Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene 14:623-625.
-
(1997)
Oncogene
, vol.14
, pp. 623-625
-
-
De Rooij, J.1
Bos, J.L.2
-
11
-
-
0026611053
-
Involvement of p21ras in activation of extracellular signal-regulated kinase 2
-
de Vries-Smits, A. M. M., B. M. T. Burgering, S. J. Leevers, C. J. Marshall, and J. L. Bos. 1992. Involvement of p21ras in activation of extracellular signal-regulated kinase 2. Nature 357:602-604.
-
(1992)
Nature
, vol.357
, pp. 602-604
-
-
De Vries-Smits, A.M.M.1
Burgering, B.M.T.2
Leevers, S.J.3
Marshall, C.J.4
Bos, J.L.5
-
12
-
-
0027953284
-
PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
-
Dhand, R., I. Hiles, G. Panayotou, S. Roche, M. J. Fry, I. Gout, N. F. Totty, O. Truong, P. Vicendo, and K. Yonezawa. 1994. PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J. 13:522-533.
-
(1994)
EMBO J.
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
-
13
-
-
0028063391
-
Evidence for the in vitro and in vivo interaction of Ras with protein kinase C-zeta
-
Diaz-Meco, M. T., J. Lozano, M. M. Municio, E. Berra, S. Frutos, L. Sanz, and J. Moscat. 1994. Evidence for the in vitro and in vivo interaction of Ras with protein kinase C-zeta. J. Biol. Chem. 269:31706-31710.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31706-31710
-
-
Diaz-Meco, M.T.1
Lozano, J.2
Municio, M.M.3
Berra, E.4
Frutos, S.5
Sanz, L.6
Moscat, J.7
-
14
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek, H., S. R. Datta, T. F. Franke, M. J. Birnbaum, R. Yao, G. M. Cooper, R. A. Segal, D. R. Kaplan, and M. E. Greenberg. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275: 661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
15
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
-
Fantl, W. J., J. A. Escobedo, G. A. Martin, C. W. Turck, M. del Rosario, and F. McCormick. 1992. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 69: 413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
Del Rosario, M.5
McCormick, F.6
-
17
-
-
0031039024
-
Direct regulation of the Akt proto-oncogenc product by phosphatidylinositol-3,4-bisphosphate
-
Franke, T. F., D. R. Kaplan, L. C. Cantley, and A. Toker. 1997. Direct regulation of the Akt proto-oncogenc product by phosphatidylinositol-3,4-bisphosphate. Science 275:665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
18
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke, T. F., S.-I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.-I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
19
-
-
0029278739
-
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
-
Hawkins, P. T., A. Eguinoa, R.-G. Qiu, D. Stokoe, F. T. Cooke, R. Walters, S. Wennström, L. Claesson-Welsh, T. Evans, M. Symons, and L. Stephens. 1995. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr. Biol. 5:393-403.
-
(1995)
Curr. Biol.
, vol.5
, pp. 393-403
-
-
Hawkins, P.T.1
Eguinoa, A.2
Qiu, R.-G.3
Stokoe, D.4
Cooke, F.T.5
Walters, R.6
Wennström, S.7
Claesson-Welsh, L.8
Evans, T.9
Symons, M.10
Stephens, L.11
-
20
-
-
0028918408
-
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
-
Hu, Q., A. Klippel, A. J. Muslin, W. J. Fantl, and L. T. Williams. 1995. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 268:100-102.
-
(1995)
Science
, vol.268
, pp. 100-102
-
-
Hu, Q.1
Klippel, A.2
Muslin, A.J.3
Fantl, W.J.4
Williams, L.T.5
-
21
-
-
0028865424
-
The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake
-
Isakoff, S. J., C. Taha, E. Rose, J. Marcusohn, A. Klip, and E. Y. Skolnik. 1995. The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake. Proc. Natl. Acad. Sci. USA 92:10247-10251.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10247-10251
-
-
Isakoff, S.J.1
Taha, C.2
Rose, E.3
Marcusohn, J.4
Klip, A.5
Skolnik, E.Y.6
-
22
-
-
0026674617
-
Receptor specificity ot growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells
-
Jackson, T. R., L. R. Stephens, and P. T. Hawkins. 1992. Receptor specificity ot growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells. J. Biol. Chem. 267:16627-16636.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16627-16636
-
-
Jackson, T.R.1
Stephens, L.R.2
Hawkins, P.T.3
-
23
-
-
0029993517
-
Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-triphosphate without subsequent activation
-
James, S. R., C. P. Downes, R. Gigg, S. J. Grove, A. B. Holmes, and D. R. Alessi. 1996. Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-triphosphate without subsequent activation. Biochem. J. 315: 709-713.
-
(1996)
Biochem. J.
, vol.315
, pp. 709-713
-
-
James, S.R.1
Downes, C.P.2
Gigg, R.3
Grove, S.J.4
Holmes, A.B.5
Alessi, D.R.6
-
24
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh, A., P. Rodriguez-Viciana, E. Ulrich, C. Gilbert, P. J. Coffer, J. Downward, and G. Evan. 1997. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385:544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.J.5
Downward, J.6
Evan, G.7
-
25
-
-
0024434183
-
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
-
Kazlauskas, A., and J. A. Cooper. 1989. Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58:1121-1133.
-
(1989)
Cell
, vol.58
, pp. 1121-1133
-
-
Kazlauskas, A.1
Cooper, J.A.2
-
26
-
-
0029831486
-
Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity
-
Klinghoffer, R. A., B. Duckworth, M. Valius, L. Cantley, and A. Kazlauskas. 1996. Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity. Mol. Cell. Biol. 16:5905-5914.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5905-5914
-
-
Klinghoffer, R.A.1
Duckworth, B.2
Valius, M.3
Cantley, L.4
Kazlauskas, A.5
-
27
-
-
0029943605
-
Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways
-
Klippel, A., C. Reinhard, W. M. Kavanaugh, G. Apell, M. A. Escobedo, and L. T. Williams. 1996. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol. Cell. Biol. 16:4117-4127.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4117-4127
-
-
Klippel, A.1
Reinhard, C.2
Kavanaugh, W.M.3
Apell, G.4
Escobedo, M.A.5
Williams, L.T.6
-
28
-
-
0031038131
-
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways
-
Marte, B. M., P. Rodriguez-Viciana, S. Wennström, P. H. Warne, and J. Downward. 1996. R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways. Curr. Biol. 7:63-70.
-
(1996)
Curr. Biol.
, vol.7
, pp. 63-70
-
-
Marte, B.M.1
Rodriguez-Viciana, P.2
Wennström, S.3
Warne, P.H.4
Downward, J.5
-
29
-
-
0028168073
-
Activation of p70/p85 S6 kinase by a pathway independent of p21ras
-
Ming, X.-F., B. M. T. Burgering, L. Claesson-Welsh, S. Wennström, C.-H. Heldin, J. L. Bos, S. C. Kozma, and G. Thomas. 1994. Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature 371:426-429.
-
(1994)
Nature
, vol.371
, pp. 426-429
-
-
Ming, X.-F.1
Burgering, B.M.T.2
Claesson-Welsh, L.3
Wennström, S.4
Heldin, C.-H.5
Bos, J.L.6
Kozma, S.C.7
Thomas, G.8
-
30
-
-
0028096233
-
The 3Rs of life: Ras, Raf and growth regulation
-
Moodie, S. A., and A. Wolfman. 1994. The 3Rs of life: Ras, Raf and growth regulation. Trends Genet. 10:44-48.
-
(1994)
Trends Genet.
, vol.10
, pp. 44-48
-
-
Moodie, S.A.1
Wolfman, A.2
-
31
-
-
0028258943
-
Rac p21 is involved in insulin-induced membrane ruffling and Rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells
-
Nishiyama, T., T. Sasaki, K. Takaishi, M. Kato, H. Yaku, K. Araki, Y. Matsuura, and Y. Takai. 1994. Rac p21 is involved in insulin-induced membrane ruffling and Rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. Mol. Cell. Biol. 14:2447-2456.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2447-2456
-
-
Nishiyama, T.1
Sasaki, T.2
Takaishi, K.3
Kato, M.4
Yaku, H.5
Araki, K.6
Matsuura, Y.7
Takai, Y.8
-
32
-
-
0028837170
-
Activation of the small GTP-binding proteins Rho and Rac by growth factor receptors
-
Nobes, C. D., P. Hawkins, L. Stephens, and A. Hall. 1995 Activation of the small GTP-binding proteins Rho and Rac by growth factor receptors. J. Cell Sci. 108:225-233.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 225-233
-
-
Nobes, C.D.1
Hawkins, P.2
Stephens, L.3
Hall, A.4
-
33
-
-
0026591788
-
Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-Ras
-
Nori, M., G. L'Allemain, and M. J. Weber. 1992. Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-Ras. Mol. Cell. Biol. 12:936-945.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 936-945
-
-
Nori, M.1
L'Allemain, G.2
Weber, M.J.3
-
34
-
-
0026487847
-
Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: Structural features and analysis of conformational changes
-
Panayotou, G., B. Bax, I. Gout, M. Ferderwisch, B. Wroblowski, R. Uhand, M. J. Fry, T. L. Blundell, A. Wollmer, and M. D. Waterfield. 1992. Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes. EMBO J. 11:4261-4272.
-
(1992)
EMBO J.
, vol.11
, pp. 4261-4272
-
-
Panayotou, G.1
Bax, B.2
Gout, I.3
Ferderwisch, M.4
Wroblowski, B.5
Uhand, R.6
Fry, M.J.7
Blundell, T.L.8
Wollmer, A.9
Waterfield, M.D.10
-
35
-
-
0026654125
-
The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
-
Ridley, A. J., H. F. Paterson, C. L. Johnston, D. Diekmann, and A. Hall. 1992. The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70:401-410.
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
36
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., P. H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M. J. Fry, M. D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370:527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
37
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., P. H. Warne, A. Khwaja, B. M. Marte, D. J. Pappin, P. Das, M. D. Waterfield, A. J. Ridley, and J. Downward. 1997. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 87:457-467.
-
(1997)
Cell
, vol.87
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.J.5
Das, P.6
Waterfield, M.D.7
Ridley, A.J.8
Downward, J.9
-
38
-
-
0029990003
-
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
-
Rodriguez-Viciana, P., P. H. Warne, B. Vanhaesebroeck, M. D. Waterfield, and J. Downward. 1996. Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J. 15:2442-2451.
-
(1996)
EMBO J.
, vol.15
, pp. 2442-2451
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Vanhaesebroeck, B.3
Waterfield, M.D.4
Downward, J.5
-
39
-
-
0028909206
-
Regulation of phosphatidylinositol 3′-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit
-
Rordorf-Nikolic, T., D. J. Van Horn, D. Chen, M. F. White, and J. M. Backer. 1995. Regulation of phosphatidylinositol 3′-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit. J. Biol. Chem. 270:3662-3666.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3662-3666
-
-
Rordorf-Nikolic, T.1
Van Horn, D.J.2
Chen, D.3
White, M.F.4
Backer, J.M.5
-
40
-
-
0028153711
-
An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: Evidence for a ret-specific signaling pathway
-
Santoro, M., W. T. Wong, P. Aroca, E. Santos, B. Matoskova, M. Grieco, A. Fusco, and P. P. Di Fiore. 1994. An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway. Mol. Cell. Biol. 14:663-675.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 663-675
-
-
Santoro, M.1
Wong, W.T.2
Aroca, P.3
Santos, E.4
Matoskova, B.5
Grieco, M.6
Fusco, A.7
Di Fiore, P.P.8
-
41
-
-
0027237273
-
A dominant-negative mutant of Raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic Ras
-
Schaap, D., J. Van der Wal, L. R. Howe, C. J. Marshall, and W. J. Blitterswijk. 1993. A dominant-negative mutant of Raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic Ras. J. Biol. Chem. 268:20232-20236.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20232-20236
-
-
Schaap, D.1
Van Der Wal, J.2
Howe, L.R.3
Marshall, C.J.4
Blitterswijk, W.J.5
-
42
-
-
0027366440
-
Agonist-stimulated synthesis of phosphatidylinositol (3,4,5)-triphosphate: A new intracellular signalling system
-
Stephens, L. R., T. R. Jackson, and P. T. Hawkins. 1993. Agonist-stimulated synthesis of phosphatidylinositol (3,4,5)-triphosphate: a new intracellular signalling system. Biochim. Biophys. Acta 1179:27-75.
-
(1993)
Biochim. Biophys. Acta
, vol.1179
, pp. 27-75
-
-
Stephens, L.R.1
Jackson, T.R.2
Hawkins, P.T.3
-
43
-
-
0029023942
-
Rho family GTPases bind to phosphoinositide kinases
-
Tolias, K. F., L. C. Cantley, and C. L. Carpenter. 1995. Rho family GTPases bind to phosphoinositide kinases. J. Biol. Chem. 270:17656-17659.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17656-17659
-
-
Tolias, K.F.1
Cantley, L.C.2
Carpenter, C.L.3
-
44
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich, A., and J. Schlessinger. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
45
-
-
0030805703
-
Phosphoinositide 3-kinases: A conserved family of signal transducers
-
Vanhaesebroeck, B., S. J. Leevers, G. Panayotou, and M. D. Waterfield. 1997. Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22:267-272.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 267-272
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Panayotou, G.3
Waterfield, M.D.4
-
46
-
-
0030953818
-
Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation
-
van Puijenbroek, A. A. F. L., D. H. J. van Weering, C. E. van den Brink, J. L. Bos, P. T. van der Saag, S. W. de Laat, and J. den Hertog. 1997. Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation. Oncogene 14:1147-1158.
-
(1997)
Oncogene
, vol.14
, pp. 1147-1158
-
-
Van Puijenbroek, A.A.F.L.1
Van Weering, D.H.J.2
Van Den Brink, C.E.3
Bos, J.L.4
Van Der Saag, P.T.5
De Laat, S.W.6
Den Hertog, J.7
-
47
-
-
0031034813
-
Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formation
-
van Weering, D. H. J., and J. L. Bos. 1997. Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formation. J. Biol. Chem. 272:249-254.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 249-254
-
-
Van Weering, D.H.J.1
Bos, J.L.2
-
49
-
-
0029565750
-
Ret receptor tyrosine kinase activates extracellular signal-regulated kinase 2 in SK-N-MC cells
-
van Weering, D. H. J., J. P. Medema, A. van Puijenbroek, B. M. T. Burgering, P. D. Baas, and J. L. Bos. 1995. Ret receptor tyrosine kinase activates extracellular signal-regulated kinase 2 in SK-N-MC cells. Oncogene 11: 2207-2214.
-
(1995)
Oncogene
, vol.11
, pp. 2207-2214
-
-
Van Weering, D.H.J.1
Medema, J.P.2
Van Puijenbroek, A.3
Burgering, B.M.T.4
Baas, P.D.5
Bos, J.L.6
-
50
-
-
0028338545
-
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85
-
Zheng, Y., S. Bagrodia, and R. A. Cerione. 1994. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J. Biol. Chem. 269: 18727-18730.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18727-18730
-
-
Zheng, Y.1
Bagrodia, S.2
Cerione, R.A.3
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