Tissue architecture: The ultimate regulator of epithelial function?

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 353, Issue 1370, 1998, Pages 857-870

  Hagios, Carmen ^a   Lochter, André ^a,b   Bissell, Mina J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTER FOR CLINICAL AND BASIC RESEARCH   (Denmark)

Author keywords

Basement membrane; Cell adhesion; Epithelium; Intestine; Mammary gland

Indexed keywords

ANIMALIA;

EID: 0032578020     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.1998.0250     Document Type: Article

References (160)

1. Adams, J. G. & Watt, F. M. 1993 Regulation of development and differentiation by the extracellular matrix. Development 117, 1183-1198.
2. Alexander, C. M., Howard, E.W., Bissell, M.J. & Werb, Z. 1996 Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 trans-gene. J. Cell Biol. 135, 1669-1677.
3. Alford, D. & Taylor-Papadimitriou, J. 1996 Cell adhesion molecules in the normal and the cancerous mammary gland. J. Mam. Gland Biol. Neoplasia 1, 207-218.
4. Alman, B. A., Li, C., Pajerski, M. E., Diaz-Cano, S. & Wolfe, H. J. 1997 Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors). Am. J. Pathol. 151, 329-334.
5. Ballard, S. T., Hunter, J. H. & Taylor, A. E. 1995 Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium. A. Rev. Nutr. 15, 35-55.
6. Barcellos-Hoff, M. H., Aggelcr, J., Ram, T. G. & Bissell, M. J. 1989 Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development 105, 223-235.
7. Earth, A. I., Pollack, A. L., Altschuler, Y, Mostov, K. E. & Nelson, W. J. 1997 NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J. Cell Biol. 136, 693-706.
8. Beaulieu, J. F. & Vachon, P. H. 1994 Reciprocal expression of laminin A-chain isoforms along the crypt-villus axis in the human small intestine. Gastroenterology 106, 829-839.
9. Behrens, J., Marcel, M. M., Van Roy, F. M. & Birchmeier, W. 1989 Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J. Cell Biol. 108, 2435-2447.
10. Behrens, J., Vakaet, L., Friis, R., Winterhager, E., Van Roy, F., Marcel, M. M. & Birchmeier, W. 1993 Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J. Cell Biol. 120, 757-766.
11. Behrens, J., von Kries, J. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R. & Birchmeier, W. 1996 Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382, 638-642.
12. Berdichevsky, F., Wetzels, R., Shearer, M., Martignone, S., Ramaekers, F. C. S. & Taylor-Papadimitriou, J. 1994 Integrin expression in relation to cell phenotype and malignant change in the human breast. Molec. Cell. Diff. 3, 255-274.
13. Bissell, M. J. & Barcellos-Hoff, M. H. 1987 The influence of extracellular matrix on gene expression: is structure the message? J. Cell Sci. 8(Suppl.), 327-343.
14. Bissell, M. J., Hall, H. G. & Parry, G. 1982 How does the extra-cellular matrix direct gene expression? J. Theor. Biol. 99, 31-68.
15. Borradori, L. & Sonnenberg, A. 1996 Hemidesmosomes: roles in adhesion, signaling and human diseases. Curr. Opin. Cell Biol. 8, 647-656.
16. Boudreau, N., Sympson, C. J., Werb, Z. & Bissell, M. J. 1995 Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267, 891-893.
17. Boudreau, N., Werb, Z. & Bisseil, M. J. 1996 Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc. Natn. Acad. Sci. USA 93, 3509-3513.
18. Boyer, B., Valles, A. M., Tucker, G. C., Delouvee, A. & Thiery, J. P. 1993 Involvement of cell motility in tumor progression. Symp. Soc. Exp. Biol. 47, 183-195.
19. Briand, P., Petersen, O. W. & Van Deurs, B. 1987 A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium. In Vitro Cell. Devl Biol. 23, 181-188.
20. Briand, P., Nielsen, K.V., Madsen, M.W. & Petersen, O. W. 1996 Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal. Cancer Res. 56, 2039-2044.
21. Bruckner-Tuderman, L. 1994 Collagen VII and bullous disorders of the skin. Dermatology 189 (Suppl. 2), 16-20.
22. Bruckner-Tuderman, L. 1996 Blistering skin diseases: models for studies on epidermal-dermal adhesion. Biochem. Cell. Biol. 74, 729-736.
23. Burgeson, R. E. (and others) 1994 A new nomenclature for the laminins. Matrix Biol. 14, 209-211.
24. Campbell, K. P. 1995 Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage. Cell 80, 675-679.
25. Chen, L. H. & Bissell, M. J. 1989 A novel regulatory mechanism for whey acidic protein gene expression. Cell Regul. 1, 45-54.
26. Chiquet, M., Matthisson, M., Koch, M., Tannheimer, M. & Chiquet-Ehrismann, R. 1996 Regulation of extracellular matrix synthesis by mechanical stress. Biochem. Cell Biol. 74, 737-744.
27. Chiquet-Ehrismann, R., Tannheimer, M., Koch, M., Brunner, A., Spring, J., Martin, D., Baumgartner, S. & Chiquet, M. 1994 Tenascin-C expression by fibroblasts is elevated in stressed collagen gels. J. Cell Biol. 127, 2093-2101.
28. Cress, A. E., Rabinovitz, L, Zhu, W. & Nagle, R. B. 1995 The alpha 6 beta 1 and alpha 6 beta 4 integrins in human prostate cancer progression. Cancer Metastasis Rev. 14, 219-228.
29. Damsky, C. H., Richa, J., Solter, D.( Knudsen, K. & Buck, C. A. 1983 Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. Cell 34, 455-466.
30. Daniel, C. W., Strickland, P. & Friedmann, Y. 1995 Expression and functional role of E- and P-cadherins in mouse mammary ductal morphogenesis and growth. Devl Biol. 169, 511-519.
31. Dauca, M., Bouziges, E, Colin, S., Kedinger, M., Keller, M. K., Schilt, J., Simon-Assmann, P. & Haffen, K. 1990 Development of the vertebrate small intestine and mechanisms of cell differentiation. Int. J. Devl Biol. 34, 205-218.
32. Deng, G., Lu,Y., Zlotnikov, G.,Thor, A. D. & Smith, H. S. 1996 Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 274, 2057-2059.
33. Dimitratos, S. D., Woods, D. F. & Bryant, P. J. 1997 Camguk, Lin-2, and CASK: novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains. Mech. Dev: 63, 127-130.
34. Doyle, J. P. & Colman, D. R. 1993 Glial-neuron interactions and the regulation of myelin formation. Curr. Opin. Cell Biol. 5, 779-785.
35. Doyle, J. P., Stempak, J. G., Cowin, P., Colman, D. R. & D'Urso, D. 1995 Protein zero, a nervous system adhesion molecule, triggers epithelial reversion in host carcinoma cells. J. Cell Biol. 131, 465-482.
36. Dufour, S., Saint-Jeannet, J. P., Broders, F., Wedlich, D. & Thiery, J. P. 1994 Differential perturbations in the morphogenesis of anterior structures induced by overexpression of truncated XB- and N-cadherins in Xenopus embryos. J. Cell Biol. 127, 521-535.
37. Ekblom, P. & Timpl, R. 1996 Cell-to-cell contact and extra-cellular matrix. A multifaceted approach emerging. Curr. Opin. Cell Biol. 8, 599-601.
38. Fannon, A. M., Sherman, D. L., Ilyina-Gragerova, G., Brophy, P. J., Friedrich, V. L. Jr & Colman, D. R. 1995 Novel E-cadherin-mediated adhesion in peripheral nerve: Schwann cell architecture is stabilized by autotypic adherens junctions J. Cell Biol. 129, 189-202. [Published erratum appears in J. Cell Biol. 129, 1721 (1995).]
39. Friedrichs, K., Ruiz, R, Franke, F., Gille, I., Terpe, H. J. & Imhof, B. A. 1995 High expression level of alpha 6 integrin in human breast carcinoma is correlated with reduced survival. Cancer Res. 55, 901-906.
40. Frixen, U. H., Behrens, J., Sachs, M., Eberle, G.,Voss, B., Warda, A., Lochner, D. & Birchmeier, W. 1991 E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J. Cell Biol. 113, 173-185.
41. Fujimori.T. & Takeichi, M. 1993 Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. Molec. Biol. Cell 4, 37-47.
42. Fujita, S., Suzuki, H., Kinoshita, M. & Hirohashi, S. 1992 Inhibition of cell attachment, invasion and metastasis of human carcinoma cells by anti-integrin β1 subunit antibody. Jap. J. Cancer Res. 83, 1317-1326.
43. Fujita, S., Watanabe, M., Kubota, T., Teramoto, T. & Kitajima, M. 1995 Alteration of expression in integrin pi subunit correlates with invasion and metastasis in colorectal cancer. Cancer Lett. 91, 145-149.
44. Gamallo, C., Palacios, J., Suarcz, A., Pizarro, A., Navarro, P., Quintanilla, M. & Cano, A. 1993 Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am. J. Pathol. 142, 987-993.
45. Glukhova, M., Koteliansky, V., Sastre, X. & Thiery, J. P. 1995 Adhesion systems in normal breast and in invasive breast carcinoma. Am. J. Pathol. 146, 706-716.
46. Gould, K. A. & Dove, W. F. 1997 Localized gene action controlling intestinal neoplasia in mice. Proc. Natn. Acad. Sci. USA 94, 5848-5853.
47. Gumbiner, B. M. 1996 Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.
48. Gumbiner, B. M. 1997 Carcinogenesis: a balance between beta-catenin and APC. Curr. Biol. 7, R443-446.
49. Hahn, U, Stallmach, A., Hahn, E. G. & Riecken, E. O. 1990 Basement membrane components are potent promoters of rat intestinal epithelial cell differentiation in vitro. Gastroenterology 98, 322-335.
50. Hay, E. D. & Zuk, A. 1995 Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am. J. Kidney Dis. 26, 678-690.
51. Hazan, R. B., Rang, L., Whooley, B. P. & Borgen, P. I. 1997 N-cadherin promotes adhesion between invasive breast cancer cells and the stroma. Cell Adhes. Commun. 4, 399-411.
52. Hermiston, M. L. & Gordon, J. I. 1995a In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J. Cell Biol. 129, 489-506.
53. Hermiston, M. L. & Gordon, J. I. 19954 Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270, 1203-1207.
54. Hermiston, M. L., Wong, M. H. & Gordon, J. I. 1996 Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev. 10, 985-996.
55. Hilkens, J., Vos, H. L., Wesseling, J., Boer, M., Storm, J., van der Valk, S., Calafat, J. & Patriarca, C. 1995 Is episialin/MUCl involved in breast cancer progression? Cancer Lett. 90, 27-33.
56. Holt, C. E., Lemaire, P. & Gurdon, J. B. 1994 Cadherinmediated cell interactions are necessary for the activation of MyoD in Xenopus mesoderm. Proc. Natn. Acad. Sci. USA 91, 10844-10848.
57. Howlett, A. R., Bailey, N., Damsky, C., Petersen, O. W. & Bissell, M. J. 1995 Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma. J. Cell Sci. 108, 1945-1957.
58. Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G. & Kemler, R. 1996 Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-10.
59. Hynes, R. O. 1992 Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
60. Hynes, R. O. 1996 Targeted mutations in cell adhesion genes: what have we learned from them? Devl Biol. 180, 402-412.
61. Ingber, D. E. 1993 Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J. Cell Sci. 104, 613-627.
62. Ingber, D. E. 1997 Tensegrity: the architectural basis of cellular mechanotransduction. A. Rev. Physiol. 59, 575-599.
63. Inomata, M., Ochiai, A., Akimoto, S., Kitano, S. & Hirohashi, S. 1996 Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients. Cancer Res. 56, 2213-2217.
64. Jesaitis, L. A. & Goodenough, D. A. 1994 Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J. Cell Biol. 124, 949-961.
65. Jones, P. H. & Watt, F. M. 1993 Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73, 713-724.
66. Jones, P. L., Schmidhauser, C. & Bissell, M.J. 1993 Regulation of gene expression and cell function by extracellular matrix. Crit. Rev. Eukaryot. Gene Expr. 3, 137-154.
67. Kato, M., Saunders, S., Nguycn, H. & Bernfield, M. 1995 Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells. Molec. Biol. Cell 6, 559-576.
68. Kedinger, M., Simon-Assmann, P. M., Lacroix, B. & Haffen, K. 1983 Role of glucocorticoids on the maturation of brush border enzymes in fetal rat gut endoderm. Experientia 39, 1150-1152.
69. Kedinger, M., Simon-Assmann, P., Bouziges, F. & Haffen, K. 1988 Epithelial-mesenchymal interactions in intestinal epithelial differentiation. Scand. J. Gastmenterol. 151(Suppl.), 62-69.
70. Keely, P. J., Wu, J. E. & Santoro, S. A. 1995 The spatial and temporal expression of the alpha 2 beta 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis. Differentiation 59, 1-13.
71. Kemler, R. 1993 From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321.
72. Kemperman, H., Wijnands, Y., Wesseling, J., Niessen, C. M., Sonnenberg, A. & Roos, E. 1994 The mucin epiglycanin on TA3/Ha carcinoma cells prevents alpha 6 beta 4-mediated adhesion to laminin and kalinin and E-cadherin-mediated cell-cell interaction. J. Cell Biol. 127, 2071-2080.
73. Kim, S. K. 1995 Tight junctions, membrane-associated guanylate kinases and cell signaling. Curr. Opin. Cell Biol. 7, 641-649.
74. Kintner, C. 1992 Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 69, 225-236.
75. Kinzler, K. W. & Vogelstein, B. 1996 Lessons from hereditary colorectal cancer. Cell 87, 159-170.
76. Koretz, K., Schlag, P., Boumsell, L. & Moller, P. 1991 Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases. Am. J. Pathol. 138, 741-750.
77. Korinek, V, Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B. & Clevers, H. 1997 Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275, 1784-1787.
78. Koukoulis, G. K., Virtanen, L, Korhonen, M., Laitinen, L., Quaranta, V. & Gould, V. E. 1991 Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules. Am. J. Pathol. 139, 787-799.
79. Kuhl, M. & Wedlich, D. 1997 Wnt signalling goes nuclear. Bioessays 19, 101-104.
80. Leivo, I.,Tani, T., Laitinen, L., Bruns, R., Kivilaakso, E., Lehto, V. P., Burgeson, R. E. & Virtanen, I. 1996 Anchoring complex components laminin-5 and type VII collagen in intestine: association with migrating and differentiating enterocytes. J. Histochem. Cytochem. 44, 1267-1277.
81. Lelievre, S., Weaver, V. M. & Bissell, M. J. 1996 Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation. Recent Prog. Horm. Res. 51, 417-432.
82. Li, M. L., Aggeler, J., Parson, D. A., Hatier, C., Hassell, J. & Bissell, M. J. 1987 Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc. Natn. Acad. Sci. USA 84, 136-140.
83. Ligtenberg, M. J., Buijs, P., Vos, H. L. & Hilkens, J. 1992 Suppression of cellular aggregation by high levels of episialin. Cancer Res. 52, 2318-2324.
84. Lin, C. Q., Dempsey, P. J., Coffcy, R. J. & Bissell, M. J. 1995 Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. J. Cell Biol. 129, 1115-1126.
85. Lochter, A. & Bissell, M. J. 1995 Involvement of extracellular matrix constituents in breast cancer. Semin. Cancer Biol. 6, 165-173.
86. Lochter, A., Srebrow, A., Sympson, C. J., Terracio, N., Werb, Z. & Bissell, M. J. 1997a Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties. J. Biol. Chem. 272, 5007-5015.
87. Lochter, A., Galosy, S., Muschler, J., Freedman, N., Werb, Z. & Bissell, M. J. 1997A Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and premalignant phenotype in mammary epithelial cells. J. Cell Biol. 139, 1861-1872.
88. Lund, L. R., Romer, J., Thomasset, N., Solberg, H., Pyke, C., Bissell, M. J., Dano, K. & Werb, Z. 1996 Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development 122, 181-193.
89. Madara, J. L. 1990 Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physio logical rearrangement of tight junctions. J. Membr. Biol. 116, 177-184.
90. Madsen, M.W., Lykkesfeldt, A. E., Laursen, L, Nielsen, K. V. & Briand, P. 1992 Altered gene expression of c-myc, epidermal growth factor receptor, transforming growth factor-alpha, and c-erb-B2 in an immortalized human breast epithelial cell line, HMT-3522, is associated with decreased growth factor requirements. Cancer Res. 52, 1210-1217.
91. Mareel, M. M., Van Roy, F. M. & De Baetselier, P. 1990 The invasive phenotypes. Cancer Metastasis Rev. 9, 45-62.
92. Mareel, M. M., Van Roy, F. M. & Bracke, M. E. 1993 How and when do tumor cells metastasize? Cut. Rev. Oncogen. 4, 559-594.
93. Marti, A., Feng, Z., Altermatt, H. J. & Jaggi, R. 1997 Milk accumulation triggers apoptosis of mammary epithelial cells. Eur. J. Cell Biol. 73, 158-165.
94. Matsuyoshi, N., Hamaguchi, M., Taniguchi, S., Nagafuchi, A., Tsukita, S. & Takeichi, M. 1992 Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118, 703-714.
95. Mercurio, A. M. 1995 Laminin receptors: achieving specificity through cooperation. Trends Cell Biol. 5, 419-423.
96. Moyret, C., Madsen, M.W., Cooke, J., Briand, P. & Theillet, C. 1994 Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522. Expl Cell Res. 215, 380-385.
97. Myers, C. A., Schmidhauser, C., Mellentin-Michelotti, J., Fragoso, G., Roskelley, C. D., Casperson, G., Mossi, R., Pujuguet, P., Hager, G. & Bissell, M. J. 1998 Characterization of BCE-1: a transcriptional enhancer regulated by prolactin and extracellular matrix and modulated by the state of histone acetylation. Molec. Cell Biol. (In the press.)
98. Natali, P. G., Nicotra, M. R., Botti, C., Mottolese, M., Bigotti, A. & Segatto, O. 1992 Changes in expression of alpha 6/beta 4 integrin heterodimer in primary and metastatic breast cancer. Br. J. Cancer 66, 318-322.
99. Nielsen, K. V. & Briand, P. 1989 Cytogenetic analysis of in vitro karyotype evolution in a cell line established from nonmalignant human mammary epithelium. Cancer Genet. Cytogenet. 39, 103-118.
100. Nielsen, K. V., Madsen, M. W. & Briand, P. 1994 In vitro karyotype evolution and cytogcnetic instability in the non-tumorigenic human breast epithelial cell line HMT-3522. Cancer Genet. Cytogenet. 78, 189-199.
101. Orian-Rousseau, V, Aberdam, D., Fontao, L., Chevalier, L., Meneguzzi, G., Kedinger, M. & Simon-Assmann, P. 1996 Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition. Devl Dyn. 206, 12-23.
102. Palacios, J., Benito, N., Pizarro, A., Suarez, A., Espada, J., Cano, A. & Gamallo, C. 1995 Anomalous expression of P-cadherin in breast carcinoma. Correlation with E-cadhcrin expression and pathological features. Am. J. Pathol. 146, 605-612.
103. Perreault, N., Vachon, P. H. & Beaulieu, J. F. 1995 Appearance and distribution of laminin A chain isoforms and integrin alpha 2, alpha 3, alpha 6, beta 1, and beta 4 subunits in the developing human small intestinal mucosa. Anat. Rec. 242, 242-250.
104. Petersen, O. W., Ronnov-Jessen, L., Howlett, A. R. & Bissell, M. J. 1992 Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natn. Acad. Sci. USA 89, 9064-9068.
105. [Published crratum appears in Proc. Natn. Acad. Sci. USA 90, 2556 (1993).]
106. Pujuguet, P., Hammann, A., Martin, F. & Martin, M. 1994 Abnormal basement membrane in tumors induced by rat colon cancer cells. Gastroenterology 107, 701-711.
107. Ranscht, B. 1994 Cadherins and catenins: interactions and functions in embryonic development. Curr. Opin. Cell Biol. 6, 740-746.
108. Rasbridge, S. A., Gillett, C. E., Sampson, S. A., Walsh, F. S. & Millis, R. R. 1993 Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma. J. Pathol. 169, 245-250.
109. Reichmann, E., Ball, R., Groner, B. & Friis, R. R. 1989 New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionallly. J. Cell Biol. 108, 1127-1138.
110. Reichmann, E., Schwarz, H., Deiner, E. M., Leitner, I., Eilers, M., Berger, J., Busslinger, M. & Beug, H. 1992 Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. Cell 71, 1103-1116.
111. Resnick, N. & Gimbrone, M. A. Jr 1995 Hemodynamic forces arc complex regulators of endothelial gene expression. FASEB J. 9, 874-882.
112. Resnick, N., Collins, T., Atkinson, W, Bonthron, D. T., Dewey, C. F. Jr & Gimbron, M. A. Jr 1993 Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc. Natn. Acad. Sci. USA 90, 7908.
113. Ronnov-Jessen, L., Petersen, O.W. & Bissell, M. J. 1996 Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol. Rev. 76, 69-125.
114. Roskelley, C. D. & Bissell, M. J. 1995 Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function. Biochem. Cell Biol. 73, 391-397.
115. Roskelley, C. D., Desprez, P. Y. & Bissell, M. J. 1994 Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc. Natn. Acad. Sci. USA 91, 12378-12382.
116. Roskelley, C. D., Srebrow, A. & Bissell, M. J. 1995 A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression. Ctirr. Opin. Cell Biol. 7, 736-747.
117. Rousselle, P., Keene, D. R., Ruggiero, F., Champliaud, M. F., Rest, M. & Burgeson, R. E. 1997 Laminin 5 binds the NC-1 domain of type VII collagen. J. Cell Biol. 138, 719-728.
118. Rubinfeld, B., Robbins, P., El-Gamil, M., Albert, I., Porfiri, E. & Polakis, P. 1997 Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science 275, 1790-1792.
119. Ryan, M. C., Christiano, A. M., Engvall, E., Wewer, U. M., Miner, J. H., Sanes, J. R. & Burgeson, R. E. 1996 The functions of laminins: lessons from in vivo studies. Matrix Biol. 15, 369-381.
120. Sakakura, T. 1991 New aspects of stroma-parenchyma relations in mammary gland differentiation. Int. Rev. Cytol. 125, 165-202.
121. Sanderson, I. R., Ezzell, R. M., Kedinger, M., Erlanger, M., Xu, Z. X., Pringault, E., Leon-Robine, S., Louvard, D. & Walker, W. A. 1996 Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix. Proc. Natn. Acad. Sci. USA 93, 7717-7722.
122. Schmidhauser, C., Casperson, G. F., Myers, C. A., Sanzo, K. T., Bolten, S. & Bissell, M. J. 1992 A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression. Molec. Biol. Cell 3, 699-709.
123. Schmidhauser, C., Casperson, G. F. & Bissell, M. J. 1994 Transcriptional activation by viral enhancers: critical dependence on extracellular matrix-cell interactions in mammary epithelial cells. Molec. Carcinog. 10, 66-71.
124. Shaw, L. M., Chao, C., Wewer, U. M. & Mercurio, A. M. 1996 Function of the integrin alpha 6 beta 1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor. Cancer Res. 56, 959-963.
125. Simon-Assmann, P. & Kedinger, M. 1993 Heterotypic cellular cooperation in gut morphogenesis and differentiation. Semin. Cell Biol. 4, 221-230.
126. Simon-Assmann, P., Duclos, B., Orian-Rousseau, V., Arnold, C., Mathelin, C., Engvall, E. & Kedinger, M. 1994 Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine. Devl Dyn. 201, 71-85.
127. Simon-Assmann, P., Kedinger, M., De Arcangelis, A., Rousseau, V. & Simo, P. 1995 Extracellular matrix components in intestinal development. Experientia 51, 883-900.
128. Sommers, C. L. 1996 The role of cadherin-mediated adhesion in breast cancer. J. Mam. Gland Biol. Neoplasia 1, 219-229.
129. Sommers, C. L., Gelmann, E. P., Kemler, R., Cowin, P. & Byers, S. W. 1994 Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res. 54, 3544-3552.
130. Sonnenberg, A., de Melker, A. A., Martinez de Velasco, A. M., Janssen, H., Calafat, J. & Niessen, C. M. 1993 Formation of hemidesmosomes in cells of a transformed murine mammary tumor cell line and mechanisms involved in adherence of these cells to laminin and kalinin. J. Cell Sci. 106, 1083-1102.
131. Stahl, S., Weitzman, S. & Jones, J. G. 1997 The role of laminin-5 and its receptors in mammary epithelial cell branching morphogenesis. J. Cell Sci. 110, 55-63.
132. Stetler-Stevenson, W. G., Aznavoorian, S. & Liotta, L. A. 1993 Tumor cell interactions with the extracellular matrix during invasion and metastasis. A. Rev. Cell Biol. 9, 541-573.
133. Stoker, A.W., Streuli, C. H., Martins-Green, M. & Bissell, M. J. 1990 Designer microenvironments for the analysis of cell and tissue function. Curr. Opin. Cell Biol. 2, 864-874.
134. Streuli, C. H. 1993 Extracellular matrix and gene expression in mammary epithelium. Semin. Cell Biol. 4, 203-212.
135. Streuli, C. H. & Bissell, M. J. 1990 Expression of extracellular matrix components is regulated by substratum. J. Cell Biol. 110, 1405-1415.
136. Streuli, C. H., Bailey, N. & Bissell, M. J. 1991 Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity. J. Cell Biol. 115, 1383-1395.
137. Streuli, C. H., Schmidhauser, C., Bailey, N., Yurchenco, P., Skubitz, A. P., Roskelley, C. & Bissell, M. J. 1995 Laminin mediates tissue-specific gene expression in mammary epithelia. J. Cell Biol. 129, 591-603.
138. Sympson, C. J., Talhouk, R. S., Alexander, C. M., Chin, J. R., Clift, S. M., Bissell, M. J. & Werb, Z. 1994 Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. J. Cell Biol. 125, 681-693.
139. Sympson, G. J., Bissell, M. J. & Werb, Z. 1995 Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1. Semin. Cancer Biol. 6, 159-163.
140. Takeichi, M. 1993 Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol. 5, 806-811.
141. Talhouk, R. S., Bissell, M. J. & Werb, Z. 1992 Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution. J. Cell Biol. 118, 1271-1282.
142. Thompson, E. W.,Torri,J., Sabol, M., Sommers, C. L., Byers, S., Valverius, E. M., Martin, G. R., Lippman, M. E., Stampfer, M. R. & Dickson, R. B. 1994 Oncogene-induced basement membrane invasiveness in human mammary epithelial cells. Clin. Expl Metastasis 12, 181-194.
143. Uematsu, J., Nishizawa, Y, Sonnenberg, A. & Owaribe, K. 1994 Demonstration of type II hemidesmosomes in a mammary gland epithelial cell line, BMGE-H. J. Biochem., Tokyo 115, 469-476.
144. Utani, A., Kopp, J. B., Kozak, C. A., Matsuki,Y, Amizuka, N., Sugiyama, S. & Yamada, Y. 1995 Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution. Lab. Inrest. 72, 300-310.
145. Vleminckx, K., Vakaet, L. Jr, Marcel, M., Fiers, W. & van Roy, F. 1991 Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66, 107-119
146. Vleminckx, K. L., Deman, J. J., Bruyneel, E. A., Vandenbossche, G. M., Keirsebilck, A. A., Marcel, M. M. & van Roy, F. M. 1994 Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells. Cancer Res. 54, 873-877.
147. Wang, F., Weaver, V M., Petersen, O. W, Larabell, G. A., Dedhar, S., Chen, H.-M., Briand, P., Lupu, R. & Bissell, M. J. 1998 Reciprocal interactions between β1-integrin and EGFR signaling pathways in human breast epithelial cells in three dimensional cultures. (Submitted.)
148. Weaver, V. M., Hewlett, A. R., Langton-Webster, B., Petersen, O. W. & Bissell, M. J. 1995 The development of a functionally relevant cell culture model of progressive human breast cancer. Semin. Cancer Biol. 6, 175-184.
149. Weaver, V. M., Fischer A. H., Petersen, O. W. & Bissell, M. J. 1996 The importance of the microenvironmcnt in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay. Biochem. Cell Biol. 74, 833-851.
150. Weaver, V. M., Petersen, O. W., Wang, F., Larabell, C. A., Briand, P., Damsky, C. & Bissell, M. J. 1997 Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol. 137, 231-245.
151. Werb, Z., Sympson, G. J., Alexander, C. M., Thomasset, N., Lund, L. R., MacAuley, A., Ashkenas, J. & Bissell, M. J. 1996 Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution. Kidney Int. 54(Suppl.), S68-74.
152. Wesseling, J., van der Valk, S. W. & Hilkens, J. 1996 A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/ MUC1. Molec. Biol. Cell 7, 565-577.
153. Wewer, U. M. & Engvall, E. 1994 Laminins. Meth. Enzymol. 245, 85-104.
154. Wong, M. H., Hermiston, M. L., Syder, A. J. & Gordon, J. I. 1996 Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium. Proc. Natn. Acad. Sci. USA 93, 9588-9593.
155. Woods, D. F., Hough, C., Peel, D., Callaini, G. & Bryant, P. J. 1996 Dig protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia. J. Cell Biol. 134, 1469-1482.
156. Xia, Y., Gil, S. G. & Carter, W. G. 1996 Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein. J. Cell Biol. 132, 727-740.
157. Zettl, K. S., Sjaastad, M. D., Riskin, P. M., Parry, G., Machen, T. E. & Firestone, G. L. 1992 Glucocorticoid-induced formation of tight junctions in mouse mammary epithelial cells in vitro. Proc. Natn. Acad. Sci. USA 89, 9069-9073.
158. Zutter, M. M., Mazoujian, G. & Santoro, S. A. 1990 Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast. Am. J. Pathol. 137, 863-870.
159. Zutter, M. M., Krigman, H. R. & Santoro, S. A. 1993 Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization. Am. J. Pathol. 142, 1439-1448.
160. Zutter, M. M., Santoro, S. A., Staatz, W. D. & Tsung,Y. L. 1995 Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells. Proc. Natn. Acad. Sci. USA 92, 7411-7415.