Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins

Postgraduate Medical Journal

Volumn 75, Issue 889, 1999, Pages 680-681

  Edwards, S G M ^a   Hubbard, V ^a   Aylett, S ^b   Wren, D ^c  

^a ST MARY S HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ATKINSON MORLEY S HOSPITAL   (United Kingdom)

Author keywords

Carbamazepine; Epilepsy; Hypersensitivity; Twins

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE;

ADOLESCENT; ARTICLE; CASE REPORT; DRUG HYPERSENSITIVITY; GENERALIZED EPILEPSY; HUMAN; MALE; MONOZYGOTIC TWINS;

EID: 0032748789     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pgmj.75.889.680     Document Type: Article

References (4)

1. Shear NH, Spielberg SP, Cannon M, Miller M. Anticonvulsant hypersensitivity syndrome: in vitro risk assessment. J Clin Invest 1988;82:1826-32.
2. Gennis MA, Vemuri R, Burns EA, Hill JV, Miller MA, Spielberg SP. Familial occurrence of hypersensitivity to phenytoin. Am J Med 1991;91:631-4.
3. Berkovic SF, Howell RA, Hay DA, Hopper JL. Twin birth is not a risk factor for seizures. Neurology 1993;43:2515-9.
4. Ashmark H, Wilholm B. Epidemiology of adverse reactions to carbamazepine as seen in a spontaneous reporting system. Acta Neurol Scand 1990;81:131-40.