메뉴 건너뛰기




Volumn 20, Issue 2, 2000, Pages 246-251

Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; DEBRISOQUINE 4 HYDROXYLASE; DESIPRAMINE; DRUG METABOLIZING ENZYME; HALOPERIDOL; IMIPRAMINE; NEUROLEPTIC AGENT; NORTRIPTYLINE; PERPHENAZINE; RISPERIDONE; THIORIDAZINE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 0001697297     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-200004000-00019     Document Type: Article
Times cited : (211)

References (29)
  • 2
    • 0029834060 scopus 로고    scopus 로고
    • Clinical importance of genetic polymorphism of drug oxidation
    • Edeki T. Clinical importance of genetic polymorphism of drug oxidation. Mt Sinai J Med 1996;63:291-300.
    • (1996) Mt Sinai J Med , vol.63 , pp. 291-300
    • Edeki, T.1
  • 3
    • 0031023815 scopus 로고    scopus 로고
    • Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency
    • Linder MW, Prough RA, Valdes R Jr. Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency. Clin Chem 1997;43: 254-66.
    • (1997) Clin Chem , vol.43 , pp. 254-266
    • Linder, M.W.1    Prough, R.A.2    Valdes R., Jr.3
  • 4
    • 0028603653 scopus 로고
    • Pharmacogenetics and drug metabolism of newer antidepressant agents
    • DeVane CL. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry 1994;55[suppl]:38-47.
    • (1994) J Clin Psychiatry , vol.55 , Issue.SUPPL. , pp. 38-47
    • DeVane, C.L.1
  • 5
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • Marez D, Legrand M, Sabbagh N, Spire C, Lafitte JJ, Meyer UA, Broly F. Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 1997;7:193-202.
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Spire, C.4    Lafitte, J.J.5    Meyer, U.A.6    Broly, F.7
  • 6
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variant in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmöller J, Bauer S, Roots I. Cytochrome P450 2D6 variant in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 1997;60:284-95.
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmöller, J.2    Bauer, S.3    Roots, I.4
  • 8
    • 0024359574 scopus 로고
    • Clinical significance of the sparteine/debrisoquine oxidation polymorphism
    • Brøsen K, Gram LF. Clinical significance of the sparteine/debrisoquine oxidation polymorphism. Eur J Clin Pharmacol 1989; 36:537-47.
    • (1989) Eur J Clin Pharmacol , vol.36 , pp. 537-547
    • Brøsen, K.1    Gram, L.F.2
  • 9
    • 0028289040 scopus 로고
    • Clinical implications of genetic polymorphism in drug metabolism
    • Tucker GT. Clinical implications of genetic polymorphism in drug metabolism. J Pharm Pharmacol 1994;46[suppl 1]:417-24.
    • (1994) J Pharm Pharmacol , vol.46 , Issue.SUPPL. 1 , pp. 417-424
    • Tucker, G.T.1
  • 10
    • 0025746716 scopus 로고
    • Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450II D6 29/29-kilobase wild-type allele-a slowly reversible interaction with fluoxetine
    • Müller N, Brockmöller J, Roots I. Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450II D6 29/29-kilobase wild-type allele-a slowly reversible interaction with fluoxetine. Ther Drug Monit 1991;13:533-6.
    • (1991) Ther Drug Monit , vol.13 , pp. 533-536
    • Müller, N.1    Brockmöller, J.2    Roots, I.3
  • 11
    • 0027471030 scopus 로고
    • Genetically determined drug-metabolizing activity and desipramine-associated cardiotoxicity: A case report
    • Bluhm RE, Wilkinson GR, Shelton R, Branch RA. Genetically determined drug-metabolizing activity and desipramine-associated cardiotoxicity: a case report. Clin Pharmacol Ther 1993;53:89-95.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 89-95
    • Bluhm, R.E.1    Wilkinson, G.R.2    Shelton, R.3    Branch, R.A.4
  • 12
    • 0029049844 scopus 로고
    • Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia
    • Arthur H, Dahl ML, Siwers B, Sjoqvist F. Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia. J Clin Psychopharmacol 1995;15:211-6.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 211-216
    • Arthur, H.1    Dahl, M.L.2    Siwers, B.3    Sjoqvist, F.4
  • 13
    • 0030809767 scopus 로고    scopus 로고
    • Antipsychotic drug-induced movement disorders in schizophrenics in relation to CYP2D6 genotype
    • Armstrong M, Daly AK, Blennerhassett R, Ferrier N, Idle JR. Antipsychotic drug-induced movement disorders in schizophrenics in relation to CYP2D6 genotype. Br J Psychiatry 1997;170:23-6.
    • (1997) Br J Psychiatry , vol.170 , pp. 23-26
    • Armstrong, M.1    Daly, A.K.2    Blennerhassett, R.3    Ferrier, N.4    Idle, J.R.5
  • 14
    • 0030659112 scopus 로고    scopus 로고
    • Seizures and myoclonus associated with antidepressant treatment: Assessment of potential risk factors, including CYP2D6 and CYP2C19 polymorphisms, and treatment with CYP2D6 inhibitors
    • Spigset O, Hedenmalm K, Dahl ML, Wiholm BE, Dahlqvist R. Seizures and myoclonus associated with antidepressant treatment: assessment of potential risk factors, including CYP2D6 and CYP2C19 polymorphisms, and treatment with CYP2D6 inhibitors. Acta Psychiatr Scand 1997;96:379-84.
    • (1997) Acta Psychiatr Scand , vol.96 , pp. 379-384
    • Spigset, O.1    Hedenmalm, K.2    Dahl, M.L.3    Wiholm, B.E.4    Dahlqvist, R.5
  • 16
    • 0031028101 scopus 로고    scopus 로고
    • Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: A prospective study
    • Spina E, Gitto C, Avenso A, Campo GM, Caputi AP, Perucca E. Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study. Eur J Clin Pharmacol 1997;51:395-8.
    • (1997) Eur J Clin Pharmacol , vol.51 , pp. 395-398
    • Spina, E.1    Gitto, C.2    Avenso, A.3    Campo, G.M.4    Caputi, A.P.5    Perucca, E.6
  • 17
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
    • Agundez JAG, Ledesma MC, Ladero JM, Benitez J. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995;57: 265-9.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agundez, J.A.G.1    Ledesma, M.C.2    Ladero, J.M.3    Benitez, J.4
  • 18
    • 0021722956 scopus 로고
    • Adverse effects from metoprolol are not generally associated with oxidation status
    • Clark DW, Morgan AKW, Waal-Manning H. Adverse effects from metoprolol are not generally associated with oxidation status. Br J Clin Pharmacol 1984;18:965-7.
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 965-967
    • Clark, D.W.1    Morgan, A.K.W.2    Waal-Manning, H.3
  • 19
    • 25544468479 scopus 로고
    • Debrisoquine oxidation, phenotyping, and adverse drug reactions: Utility of phenotyping in general hospital admissions
    • Wynne H, Lancaster R, Oates NS, Crothers MJ, Idle JR, Smith RL. Debrisoquine oxidation, phenotyping, and adverse drug reactions: utility of phenotyping in general hospital admissions. Proc Br Pharmacol Soc 1985;20:254P-255P.
    • (1985) Proc Br Pharmacol Soc , vol.20
    • Wynne, H.1    Lancaster, R.2    Oates, N.S.3    Crothers, M.J.4    Idle, J.R.5    Smith, R.L.6
  • 22
    • 0007293059 scopus 로고    scopus 로고
    • Utrarapid metabolizers of debrisoquine: Characterization and CYP-based detection of alleles with duplication of the CYP2D6 gene
    • Lovlie R, Daly AK, Molven A, Idle JR, Steen VM. Utrarapid metabolizers of debrisoquine: characterization and CYP-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett 1996;392:30-4.
    • (1996) FEBS Lett , vol.392 , pp. 30-34
    • Lovlie, R.1    Daly, A.K.2    Molven, A.3    Idle, J.R.4    Steen, V.M.5
  • 24
    • 0029853664 scopus 로고    scopus 로고
    • A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: Association with diminished debrisoquine hydroxylase activity
    • Masimirembwa C, Persson I, Bertilsson L, Hasler J, Ingelman-Sundberg M. A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity. Br J Clin Pharmacol 1996;42:713-9.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 713-719
    • Masimirembwa, C.1    Persson, I.2    Bertilsson, L.3    Hasler, J.4    Ingelman-Sundberg, M.5
  • 25
    • 0025080352 scopus 로고
    • Genotyping of poor metabolizers of debrisoquine by allele-speciflc PCR amplification
    • Heim M, Meyer UA. Genotyping of poor metabolizers of debrisoquine by allele-speciflc PCR amplification. Lancet 1990;336: 529-32.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 26
    • 0030938177 scopus 로고    scopus 로고
    • Characterization of the 16+9 kb and 30+9 kb CYP2D6 XbaI haplotypes
    • Lovlie R, Daly AK, Idle JR, Steen VM. Characterization of the 16+9 kb and 30+9 kb CYP2D6 XbaI haplotypes. Pharmacogenetics 1997;7:149-52
    • (1997) Pharmacogenetics , vol.7 , pp. 149-152
    • Lovlie, R.1    Daly, A.K.2    Idle, J.R.3    Steen, V.M.4
  • 28
    • 0029915406 scopus 로고    scopus 로고
    • Cystic fibrosis mutation detection by hybridization to light generated DNA probe arrays
    • Cronin MT, Fusini RV, Kim SM, Masino RS, Wespi RM, Miyada CB. Cystic fibrosis mutation detection by hybridization to light generated DNA probe arrays. Hum Mutat 1996;7:244-55.
    • (1996) Hum Mutat , vol.7 , pp. 244-255
    • Cronin, M.T.1    Fusini, R.V.2    Kim, S.M.3    Masino, R.S.4    Wespi, R.M.5    Miyada, C.B.6
  • 29
    • 0031960093 scopus 로고    scopus 로고
    • Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine
    • Sachse C, Brockmöller J, Hildebrand M, Müller K, Roots I. Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine. Pharmacogenetics 1998;8:181-5.
    • (1998) Pharmacogenetics , vol.8 , pp. 181-185
    • Sachse, C.1    Brockmöller, J.2    Hildebrand, M.3    Müller, K.4    Roots, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.