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Volumn 5, Issue 3, 2001, Pages 285-291

Applications of NMR in drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND;

EID: 0035358813     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00204-0     Document Type: Review
Times cited : (107)

References (61)
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    • NMR techniques for characterization of ligand binding: Utility for lead generation and optimization in drug discovery
    • (1999) Biopolymers , vol.51 , pp. 221-243
    • Moore, J.M.1
  • 10
    • 0034003170 scopus 로고    scopus 로고
    • Transverse relaxation optimised spin-state selective NMR experiments for measurement of residual dipolar couplings
    • (2000) J Biomol NMR , vol.16 , pp. 221-227
    • Permi, P.1    Annila, A.2
  • 12
    • 0037551646 scopus 로고    scopus 로고
    • Alignment of biological macromolecules in novel nonionic liquid crystalline media for NMR experiments
    • (2000) J Am Chem Soc , vol.122 , pp. 7793-7797
    • Rückert, M.1    Otting, G.2
  • 20
    • 0032494393 scopus 로고    scopus 로고
    • NOE pumping: A novel NMR technique for identification of compounds with binding affinity to macromolecules
    • (1998) J Am Chem Soc , vol.120 , pp. 10258-10259
    • Chen, A.1    Shapiro, M.J.2
  • 21
    • 0033963395 scopus 로고    scopus 로고
    • NOE pumping. 2. A high-throughput method to determine compounds with binding affinity to macromolecules by NMR
    • (2000) J Am Chem Soc , vol.122 , pp. 414-415
    • Chen, A.1    Shapiro, M.J.2
  • 30
    • 0034212746 scopus 로고    scopus 로고
    • Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy
    • (2000) J Med Chem , vol.43 , pp. 2093-2099
    • Mayer, M.1    Meyer, M.2
  • 32
    • 0034725387 scopus 로고    scopus 로고
    • Application of NMR based binding assays to identify key hydroxy groups for intermolecular recognition
    • (2000) J Am Chem Soc , vol.122 , pp. 6093-6099
    • Vogtherr, M.1    Peters, T.2
  • 33
    • 0034164238 scopus 로고    scopus 로고
    • Improving bioaffinity NMR spectra by means of zero-quantum dephasing
    • (2000) Magn Reson Chem , vol.38 , pp. 315-318
    • Weimar, T.1
  • 36
    • 0004371194 scopus 로고    scopus 로고
    • Group epitope mapping (GEM) to identify segments of a ligand in direct contact with a protein: STD NMR as a tool to characterize binding to Ricinus communis agglutinin
    • in press
    • (2001) J Am Chem Soc
    • Mayer, M.1    Meyer, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.