The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function- associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules

Journal of Experimental Medicine

Volumn 191, Issue 1, 2000, Pages 61-75

  Stein, Jens V ^a   Rot, Antal ^b   Luo, Yi ^a   Narasimhaswamy, Manjunath ^a   Nakano, Hideki ^c   Gunn, Michael D ^d   Matsuzawa, Akio ^e   Quackenbush, Elizabeth J ^a   Dorf, Martin E ^a   Von Andrian, Ulrich H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Brunnerstra e 59   (Austria)

^c TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adhesion; Homing; Intravital microscopy; T cell

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; GREEN FLUORESCENT PROTEIN; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM; LYMPH NODE; LYMPH VESSEL; LYMPHOCYTE HOMING; LYMPHOID TISSUE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; STROMA CELL; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE; VENULE;

ANIMALS; CELL MOVEMENT; CHEMOKINES, CC; CHEMOKINES, CXC; ENDOTHELIUM, LYMPHATIC; LYMPH NODES; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; T-LYMPHOCYTES;

EID: 17144442408     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.1.61     Document Type: Article

References (64)

1. Gowans, J.L., and E.J. Knight. 1964. The route of re-circulation of lymphocytes in the rat. Proc. R. Soc. Lond. Ser. B. 159: 257-282.
2. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multi-step paradigm. Cell. 76:301-314.
3. Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science. 272:60-66.
4. Mondino, A., A. Khoruts, and M.K. Jenkins. 1996. The anatomy of T-cell activation and tolerance. Proc. Natl. Acad. Sci. USA. 93:2245-2252.
5. Catalina, M.D., M.C. Carroll, H. Arizpe, A. Takashima, P. Estess, and M.H. Siegelman. 1996. The route of antigen entry determines the requirement for L-selectin during immune responses. J. Exp. Med. 184:2341-2351.
6. Diacovo, T.G., M.D. Catalina, M.H. Siegelman, and U.H. von Andrian. 1998. Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice. J. Exp. Med. 187:197-204.
7. Warnock, R.A., S. Askari, E.C. Butcher, and U.H. von Andrian. 1998. Molecular mechanisms ot lymphocyte homing to peripheral lymph nodes. J. Exp. Med. 187:205-216.
8. Berg, E.L., M.K. Robinson, R.A. Warnock, and E.C. Butcher. 1991. The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor. J. Cell Biol. 114:343-349.
9. Streeter, P.R., B.T.N. Rouse, and E.C. Butcher. 1988. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J. Cell Biol. 107:1853-1862.
10. von Andrian, U.H. 1996. Intravital microscopy of the peripheral lymph node microcirculation in mice. Microcirculation. 3:287-300.
11. Gallatin, W.M., I.L. Weissman, and E.C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature. 304:30-34.
12. Arbonès, M.L., D.C. Ord, K. Ley, H. Ratech, C. Maynard-Curry, G. Otten, D.J. Capon, and T.F. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity. 1:247-260.
13. Hamann, A., D.J. Westrich, A. Duijvestijn, E.C. Butcher, H. Baisch, R. Harder, and H.G. Thiele. 1988. Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing. J. Immunol. 140:693-699.
14. Andrew, D.P., J.P. Spellberg, H. Takimoto, R. Schmits, T.W. Mak, and M.M. Zukowski. 1998. Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice. Eur. J. Immunol. 28:1959-1969.
15. Berlin-Rufenbach, C., F. Otto, M. Mathies, J. Westermann, M.J. Owen, A. Hamann, and N. Hogg. 1999. Lymphocyte migration in lymphocyte function-associated (LFA)-1-deficient mice. J. Exp. Med. 189:1467-1478.
16. Stewart, M., and N. Hogg. 1996. Regulation of leukocyte integrin function: affinity vs. avidity. J. Cell. Biochem. 61: 554-561.
17. Spangrude, G.J., B.A. Braaten, and R.A. Daynes. 1984. Molecular mechanisms of lymphocyte extravasation. I. Studies of two selective inhibitors of lymphocyte recirculation. J. Immunol. 132:354-362.
18. Rollins, B.J. 1997. Cheniokines. Blood. 90:909-928.
19. Kim, C.H., and H.E. Broxmeyer. 1999. Chemokines: signal lamps for trafficking of T and B cells for development and effector function. J. Leukoc, Biol. 65:6-15.
20. Tanabe, S., Z. Lu, Y. Luo, E.J. Quckenbush, M.A. Berman, L.A. Collins-Racie, S. Mi, C. Reilly, D. Lo, K.A. Jacobs, and M.E. Dorf. 1997. Identification of a new mouse β-chemokine, TCA-4, with activity on T lymphocytes and mesangial cells. J. Immunol. 159:5671-5679.
21. Hedrick, J.A., and A. Zlotnik. 1997. Identification and characterization of a novel β chemokine containing six conserved cysteines. Immunol 159:1589-1593.
22. Gunn, M.D., K. Tangemann, C. Tam, J.G. Cyster, S.D. Rosen, and L.T. Williams. 1998. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl. Acad. Sci. USA. 95:258-263.
23. Nagira, M., T. Imai, K. Hieshima, J. Kusuda, M. Ridanpaa, S. Takagi, M. Nishimura, M. Kakizaki, H. Nomiyama, and O. Yoshie. 1997. Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13 J. Biol. Chem. 272:19518-19524.
24. Campbell, J.J., E.P. Bowman, K. Murphy, K.R. Youngman, M.A. Siani, D.A. Thompson, L. Wu, A. Zlotnik, and E.C. Butcher. 1998. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7. J. Cell Biol. 141: 1053-1059.
25. Yoshida, R., M. Nagira, M. Kitaura, N. Imagawa, T. Imai, and O. Yoshie. 1998. Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. J. Biol. Chem. 273:7118-7122.
26. Yoshida, R., M. Nagira, T. Imai, M. Baba, S. Takagi, Y. Tabira, J. Akagi, H. Nomiyama, and O. Yoshie. 1998. EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC. Int. Imnumol. 10:901-910.
27. Ngo, V.N., H.L. Tang, and J.G. Cyster. 1998. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells. J. Exp. Med. 188:181-191.
28. Campbell, J.J., J. Hedrick, A. Zlotnik, M.A. Siani, D.A. Thompson, and E.C. Butcher. 1998. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science. 279:381-384.
29. Tangemann, K., M.D. Gunn, P. Giblin, and S.D. Rosen. 1998. A high-endothelial cell derived chemokine induces rapid, efficient, and subset-specific arrest of rolling T lymphocytes on a reconstituted endothelial substrate. J. Immunol. 161:6330-6337.
30. Pachynski, R.K., S.W. Wu, M.D. Gunn, and D.J. Erle. 1998. Secondary lymphoid-tissue chemokine (SLC) stimulates integrin α4β7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow. J. Immunol. 161:952-956.
31. Nakano, H., T. Tamura, T. Yoshimoto, H. Yagita, M. Miyasaka, E.C. Butcher, H. Nariuchi, T. Kakiuchi, and A. Matsuzawa. 1997. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur. J. Immunol. 27:215-221.
32. Nakano, H., S. Mori, H. Yonekawa, H. Nariuchi, A. Matsuzawa, and T. Kakiuchi. 1998. A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4. Blood. 91:2886-2895.
33. Gunn, M.D., S. Kyuwa, C. Tain, T. Kakiuchi, A. Matsuzawa, L.T. Williams, and H. Nakano. 1999. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189:451-460.
34. Sanchez-Madrid, F., P. Simon, S. Thompson, and T.A. Springer. 1983. Mapping of antigenic and functional epitopes on the alpha and beta subunits of two related glycoproteins involved in cell interactions, LFA-1 and Mac-1. J. Exp. Med. 158:586-602.
35. + effector T cell differentiation in vivo. Proc. Natl. Acad. Sci. USA. 96:13932-13937.
36. von Andrian, U.H., and C. M'rini. 1998. In situ analysis of lymphocyte migration to lymph nodes. Cell Adhes. Commun. 6:85-96.
37. Pries, A.R. 1988. A versatile video image analysis system for microcirculatory research. Int. J. Microcirc. Clin. Exp. 7:327-345.
38. Stockton, B.M., G. Cheng, N. Manjunath, B. Ardman, and D.H. von Andrian. 1998. Negative regulation of T cell homing by CD43. Immunity. 8:373-381.
39. Sawada, S., J.D. Scarborough, N. Killeen, and D.R. Littman. 1994. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell. 77:917-929.
40. Oberlin, E., A. Amara, F. Bachelerie, C. Bessia, J.-L. Virelizier, A. Arenzana-Seisdedos, O. Schwartz, J.-M. Heard, I. Clark-Lewis, D.F. Legler, et al. 1996. The CXC chemokine, stromal cell derived factor 1 (SDF-1), is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 382:833-835.
41. Bleul, C.C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, J. Sodroski, and T.A. Springer. 1996. The lymphocyte chemoattractant SHF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature. 382:829-833.
42. Bargatze, R.F., M.A. Jutila, and E.C. Butcher. 1995. Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined. Immunity. 3:99-108.
43. Nagira, M., T. Imai, R. Yoshida, S. Takagi, M. Iwasaki, M. Baba, Y. Tabira, J. Akagi, H. Nomiyama, and O. Yoshie. 1998. A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cells. Eur. J. Immunol. 28: 1516-1523.
44. Miura, S., Y. Tsuzuki, D. Fukumara, H. Serizawa, M. Suematsu, I. Kurose, H. Imaeda, H. Kimura, H. Nagata, M. Tsuchiya, et al. 1995. Intravital demonstration of sequential migration process ot lymphocyte subpopulations in rat Peyer's patches. Gastroenterology. 109:1113-1123.
45. Stevens, S.K., I.L. Weissman, and E.C. Butcher. 1982. Differences in the migration of B and T lymphocytes. Organ-selective localization in vivo and the role of lymphocyte-endothelial cell recognition. J. Immunol. 2:844-851.
46. Quackenbush, E. J., V. Aguirre, B.K. Wershil, and J.C. Gutierrez-Ramos. 1997. Eotaxin influences the development of embryonic hematopoietic progenitors in the mouse. J. Leukoc. Biol. 62:661-666.
47. Yoshida, R., T. Imai, K. Hieshima, J. Kusuda, M. Baba, M. Kitaura, M. Nishimura, M. Kakizaki, H. Nomiyama, and O. Yoshie. 1997. Molecular cloning of a novel human CC chemokine EB11-ligand chemokine that is a specific functional ligand for EB11. CCR7. J. Biol. Chem. 272:13803-13809.
48. Soto, H., W. Wang, R.M. Stricter, N.G. Copeland, D.J. Gilbert, N.A. Jenkins, J. Hedrick, and A. Zlotnik. 1998. The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc. Natl. Acad. Sci. USA. 95:8205-8210.
49. Ma, Q., D. Jones, and T.A. Springer. 1999. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity. 10:463-471.
50. Kim, C.H., L.M. Pelus, J.R. White, E. Applebaum, K. Johanson, and H.E. Broxmeyer. 1998. CKbeta-11/macrophage inflammatory protein-3beta/EB11-ligand chemokine is an efficacious chemoattractant for T and B cells. J. Immunol. 160: 2418-2424.
51. Bleul, C.C., R.C. Fuhlbrigge, J.M. Casasnovas, A. Aiuti, and T. A. Springer. 1996. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J. Exp. Med. 184:1101-1110.
52. Girard, J.-P., and T.A. Springer. 1995. High endothelial venules (HEVs): specialized endothelium for lymphocyte migration, Immunol. Today. 16:449-457.
53. Middleton, J., S. Neil, J. Winde, I. Clark-Lewis, H. Moore, C. Lam, M. Auer, E. Hub, and A. Rot. 1997. Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell. 91:1001-1011.
54. Rot, A. 1992. Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration. Immunol. Today. 13:291-294.
55. Tanaka, Y., D.H. Adams, S. Hubscher, H. Hirano, U. Siebenlist, and S. Shaw. 1993. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1beta. Nature. 361:79-82.
56. Hub, E., and A. Rot. 1998. Binding of RANTES, MCP-1, MCP-3, and MIP-1α to cells in human skin. Am. J. Pathol. 152:749-757.
57. Anderson, A.O., and S. Shaw. 1993. T cell adhesion to endothelium: the FRC conduit system and other anatomic and molecular features which facilitate the adhesion cascade in lymph node. Semin. Immunol. 5:271-282.
58. Gretz, J.E., E.P. Kaldjian, A.O. Anderson, and S. Shaw. 1996. Sophisticated strategies for information encounter in the lymph node. J. Immunol. 157:495-499.
59. Wagner, L., O.O. Yang, E.A. Garcia-Zepeda, Y. Ge, S.A. Kalams, B.D. Walker, M.S. Pasternack, and A.D. Luster. 1998. β-chemokines are released from HIV-1-specific cytolytic T-cell granules complexeed to proteoglycans. Nature. 391:908-911.
60. Hendriks, H.R., and I.L. Eestermans. 1983. Disappearance and reappearance of high endothelial venules and immigrating lymphocytes in lymph nodes deprived of afferent lymphatic vessels: a possible regulatory role of macrophages in lymphocyte migration. Eur. J. Immunol. 13:663-669.
61. Hendriks, H.R., A.M. Duijvestijn, and G. Kraal. 1987. Rapid decrease in lymphocyte adherence to high endothelial venules in lymph nodes deprived of afferent lymphatic vessels. Eur. J. Immunol. 17:1691-1695.
62. Mebius, R.E., P.R. Streeter, J. Breve, A.M. Duijvestijn, and G. Kraal. 1991. The influence of afferent lymphatic vessel interruption on vascular addressin expression. J. Cell Biol. 115: 85-95.
63. Tedla, N., H.W. Wang, H.P. McNeil, N. DiGirolamo, T. Hampartzoumain, D. Wakefield, and A. Lloyd. 1998. Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1α and MIP-1β. J. Immunol. 161: 5663-5672.
64. Vassileva, G., H. Soto, A. Zlotnik, H. Nakano, T. Kakiuchi, J.A. Hedrick, and S.A. Lira. 1999. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes. J. Exp. Med. 190:1183-1188.