Follicular homing T helper (Th) cells and the Th1/Th2 paradigm

Journal of Experimental Medicine

Volumn 192, Issue 11, 2000, Pages

  Mackay, Charles R ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD28 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; TRANSCRIPTION FACTOR;

ANTIBODY PRODUCTION; B LYMPHOCYTE; HELPER CELL; HUMAN; LYMPH FOLLICLE; LYMPHOID TISSUE; NONHUMAN; NOTE; PRIORITY JOURNAL;

EID: 0034606335     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.11.F31     Document Type: Note

References (30)

1. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
2. The role of helper T cell products in mouse B cell differentiation and isotype regulation
3. Functional diversity of helper T lymphocytes
4. Transcription factors in lymphocyte development - T and B cells get together
5. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
6. T-cell subsets: Transcriptional control in the Th1/Th2 decision
7. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
8. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
9. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
10. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils
11. T cell function and migration. Two sides of the same coin
12. CCR5 is characteristic of Th1 lymphocytes
13. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
14. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
15. Visualization of specific B and T lymphocyte interactions in the lymph node
16. Chemokines and cell migration in secondary lymphoid organs
17. In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines
18. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
19. A chemokine-driven positive feedback loop organizes lymphoid follicles
20. Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells
21. T-cell co-stimulation through B7RP-1 and ICOS
22. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
23. Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection
24. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
25. Essential role of Stat6 in IL-4 signalling
26. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
27. Immune responses of IL-4, IL-5, IL-6 deficient mice
28. + T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo
29. The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo
30. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations