Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation

Current Biology

Volumn 10, Issue 6, 2000, Pages 325-328

  Agace, W W ^a   Amara, A ^b   Roberts, A I ^c   Pablos, J L ^d   Thelen, S ^e   Uguccioni, M ^e   Li, X Y ^a   Marsal, J ^a   Arenzana Seisdedos, F ^b   Delaunay, T ^f   Ebert, E C ^c   Moser, B ^e   Parker, C M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b INSTITUT PASTEUR   (France)

^c ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^e UNIVERSITY OF BERN   (Switzerland)

^f CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA; SIMIAE;

EID: 0034704853     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00380-8     Document Type: Article

References (25)

1. Fauci AS: Host factors and the pathogenesis of HIV-induced disease. Nature 1996, 384:529-534.
2. Zhu T, Wang N, Carr A, Nam DS, Moor-Jankowski R, Cooper DA, et al.: Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission. J Virol 1996, 70:3098-3107.
3. van't Wout AB, Kootstra NA, Mulder-Kampinga GA, Albrecht-van Lent N, Scherpbier HJ, Veenstra J, et al.: Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J Clin Invest 1994, 94:2060-2067.
4. Delwart EL, Mullins JI, Gupta P, Learn GH Jr, Holodniy M, Katzenstein D, et al.: Human immunodeficiency virus type 1 populations in blood and semen. J Virol 1998, 72:617-623.
5. Lapenta C, Boirivant M, Marini M, Santini SM, Logozzi M, Viora M, et al.: Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection. Eur J Immunol 1999, 29:1202-1208.
6. Harouse JM, Gettie A, Tan RCH, Blanchard J, Cheng-Mayer C: Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs. Science 1999, 284:816-819.
7. Zagury D, Lachgar A, Chams V, Fall LS, Bernard J, Zagury JF, et al.: C-C chemokines, pivotal in protection against HIV type 1 infection. Proc Natl Acad Sci USA 1998, 95:3857-3861.
8. Paxton WA, Martin SR, Tse D, O'Brien TR, Skurnick J, VanDevanter NL, et al.: Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat Med 1996, 2:412-417.
9. Garzino-Demo A, DeVico AL, Cocchi F, Gallo RC: Beta-chemokines and protection from HIV type 1 disease. AIDS Res Hum Retroviruses 1998, 14(Suppl 2):S177-S184.
10. Amara A, Lorthioir O, Valenzuela A, Magerus A, Thelen M, Montes M, et al.: Stromal cell-derived factor-1 alpha associates with heparan sulfates through the first beta-strand of the chemokine. J Biol Chem 1999, 274:23916-23925.
11. Amara A, Gall SL, Schwartz O, Salamero J, Montes M, Loetscher P, et al.: HIV coreceptor downregulation as antiviral principle: SDF-1 alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med 1997, 186:139-146.
12. Signoret N, Oldridge J, Pelchen-Matthews A, Klasse PJ, Tran T, Brass LF, et al.: Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J Cell Biol 1997, 139:651-664.
13. Ebert EC: Proliferative responses of human intraepithelial lymphocytes to various T-cell stimuli. Gastroenterology 1989, 97:1372-1381.
14. Bermejo M, Martin-Serrano J, Oberlin E, Pedraza MA, Serrano A, Santiago B, et al.: Activation of blood T lymphocytes down-regulates CXCR4 expression and interferes with propagation of X4 HIV strains. Eur J Immunol 1998, 28:3192-3204.
15. Peacock JW, Jirik FR: TCR activation inhibits chemotaxis toward stromal cell-derived factor-1 : evidence for reciprocal regulation between CXCR4 and the TCR. J Immunol 1999, 162:215-223.
16. + T cells. Science 1997, 276:273-276.
17. Zoeteweij JP, Golding H, Mostowski H, Blauvelt A: Cytokines regulate expression and function of the HIV coreceptor CXCR4 on human mature dendritic cells. J Immunol 1998, 161:3219-3223.
18. Galli G, Annunziato F, Mavilia C, Romagnani P, Cosmi L, Manetti R, et al.: Enhanced HIV expression during Th2-oriented responses explained by the opposite regulatory effect of IL-4 and IFN-gamma of fusin/CXCR4. Eur J Immunol 1998, 28:3280-3290.
19. Gupta SK, Lysko PG, Pillarisetti K, Ohlstein E, Stadel JM: Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J Biol Chem 1998, 273:4282-4287.
20. + T cell depletion and viral replication in SIV infection. Science 1998, 280:427-431.
21. + T cells. Science 1999, 286:1353-1357.
22. Zaitseva M, Blauvelt A, Lee S, Lapham CK, Klaus-Kovtun V, Mostowski H, et al.: Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection. Nat Med 1997, 3:1369-1375.
23. Reece JC, Handley AJ, Anstee EJ, Morrison WA, Crowe SM, Cameron PU: HIV-1 selection by epidermal dendritic cells during transmission across human skin. J Exp Med 1998, 187:1623-1631.
24. Shirozu M, Nakano T, Inazawa J, Tashiro K, Tada H, Shinohara T, et al.: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics 1995, 28:495-500.
25. Zabel BA, Agace WW, Campbell JJ, Heath HM, Parent D, Roberts AI, et al.: Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 1999, 190:1241-1256.